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D. Fraser · SciRah

Researcher profile · Semantic Scholar

D. Fraser

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D. Fraser — researcher profile on SciRah

h-index: 35
Works: 80
Citations: 3,897

Most-cited papers

The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal
Marcela Rosas, Luke C. Davies, P. Giles, Chia-Te Liao +6 more
2014Science365 citations Open access
Semantic Scholar
Loss of MicroRNA-192 promotes fibrogenesis in diabetic nephropathy.
A. Krupa, R. Jenkins, D. Luo, Aled Lewis +2 more
2010Journal of the American Society of Nephrology362 citations Open access
Semantic Scholar
Distinct bone marrow-derived and tissue resident macrophage-lineages proliferate at key stages during inflammation
Luke C. Davies, Marcela Rosas, S. Jenkins, Chia-Te Liao +6 more
2013Nature Communications329 citations Open access
Semantic Scholar
A quantifiable proliferative burst of tissue macrophages restores homeostatic macrophage populations after acute inflammation
Luke C. Davies, Marcela Rosas, Paul J. Smith, D. Fraser +2 more
2011European Journal of Immunology236 citations
Semantic Scholar
MicroRNAs, transforming growth factor beta‐1, and tissue fibrosis
Timothy Bowen, R. Jenkins, D. Fraser
2013Journal of Pathology166 citations
Semantic Scholar
Hyaluronan Regulates Transforming Growth Factor-β1 Receptor Compartmentalization*
Takafumi Ito, John D. Williams, D. Fraser, A. Phillips
2004Journal of Biological Chemistry147 citations Open access
Semantic Scholar
MicroRNAs in Diabetic Nephropathy: From Biomarkers to Therapy
Kate Simpson, Alexa Wonnacott, D. Fraser, Timothy Bowen
2016Current Diabetes Reports146 citations Open access
Semantic Scholar
TGF-beta1-mediated alterations of renal proximal tubular epithelial cell phenotype.
Ya-Chung Tian, D. Fraser, L. Attisano, A. Phillips
2003AJP - Renal Physiology107 citations
Semantic Scholar
Kidney ischaemia reperfusion injury in the rat: the EGTI scoring system as a valid and reliable tool for histological assessment
R. Chavez, D. Fraser, Timothy Bowen, R. Jenkins +3 more
2016105 citations Open access
Semantic Scholar
Interleukin-6 in renal disease and therapy.
Simon A. Jones, D. Fraser, C. Fielding, Gareth W. Jones
2015Nephrology, Dialysis and Transplantation94 citations
Semantic Scholar
Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular epithelial cells.
Takafumi Ito, John D. Williams, D. Fraser, A. Phillips
2004American Journal of Pathology83 citations Open access
Semantic Scholar
Association of Elevated Urinary miR-126, miR-155, and miR-29b with Diabetic Kidney Disease.
C. Beltrami, Kate Simpson, M. Jesky, Alexa Wonnacott +11 more
2018American Journal of Pathology80 citations Open access
Semantic Scholar
Single-Nucleus RNA Sequencing Identifies New Classes of Proximal Tubular Epithelial Cells in Kidney Fibrosis
Yueh-an Lu, Chia-Te Liao, R. Raybould, Bnar Talabani +6 more
2021Journal of the American Society of Nephrology78 citations Open access
Semantic Scholar
Long-term exposure of proximal tubular epithelial cells to glucose induces transforming growth factor-beta 1 synthesis via an autocrine PDGF loop.
D. Fraser, N. Brunskill, Takafumi Ito, A. Phillips
2003American Journal of Pathology78 citations Open access
Semantic Scholar
Peritoneal macrophage heterogeneity is associated with different peritoneal dialysis outcomes
Chia-Te Liao, R. Andrews, Leah E Wallace, M. Khan +4 more
2017Kidney International75 citations Open access
Semantic Scholar
Post-Transcriptional Regulation of Transforming Growth Factor Beta-1 by MicroRNA-744
John Martin, R. Jenkins, Rasha Bennagi, A. Krupa +3 more
2011PLoS ONE75 citations Open access
Semantic Scholar
Independent regulation of transforming growth factor-beta1 transcription and translation by glucose and platelet-derived growth factor.
D. Fraser, L. Wakefield, A. Phillips
2002American Journal of Pathology73 citations Open access
Semantic Scholar
Machine-learning algorithms define pathogen-specific local immune fingerprints in peritoneal dialysis patients with bacterial infections
Jingjing Zhang, Ida M. Friberg, A. Kift-Morgan, G. Parekh +11 more
2017Kidney International66 citations Open access
Semantic Scholar
Interleukin-1 beta regulates proximal tubular cell transforming growth factor beta-1 signalling.
D. Luo, C. Fielding, A. Phillips, D. Fraser
2009Nephrology, Dialysis and Transplantation58 citations Open access
Semantic Scholar
Biomarker research to improve clinical outcomes of peritoneal dialysis: consensus of the European Training and Research in Peritoneal Dialysis (EuTRiPD) network.
C. Aufricht, R. Beelen, M. Eberl, M. Fischbach +8 more
2017Kidney International56 citations Open access
Semantic Scholar
Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell Smad3 signaling via increased SnoN expression.
D. Luo, A. Phillips, D. Fraser
2010American Journal of Pathology56 citations Open access
Semantic Scholar
Toll-Like Receptors 2 and 4 Are Potential Therapeutic Targets in Peritoneal Dialysis-Associated Fibrosis.
A. Raby, Chantal S. Colmont, A. Kift-Morgan, J. Köhl +4 more
2017Journal of the American Society of Nephrology55 citations Open access
Semantic Scholar
Differential expression of microRNA miR-150-5p in IgA nephropathy as a potential mediator and marker of disease progression.
I. Pawluczyk, A. Didangelos, S. Barbour, L. Er +11 more
2021Kidney International53 citations Open access
Semantic Scholar
Unconventional human T-cells accumulate at the site of infection in response to microbial ligands and induce local tissue remodeling
A. R. Liuzzi, A. Kift-Morgan, Melisa Lopez-Anton, Ida M. Friberg +12 more
2016Journal of Immunology53 citations Open access
Semantic Scholar
Growth Factors, Cytokines, Cell Cycle Molecules ERK, p38, and Smad Signaling Pathways Differentially Regulate Transforming Growth Factor- 1 Autoinduction in Proximal Tubular Epithelial Cells
Mei Zhang, D. Fraser, A. Phillips
200652 citations
Semantic Scholar
Sp1 and Sp3 Mediate Constitutive Transcription of the Human Hyaluronan Synthase 2 Gene*
James Monslow, John D. Williams, D. Fraser, D. Michael +9 more
2006Journal of Biological Chemistry51 citations Open access
Semantic Scholar
miR-192 induces G2/M growth arrest in aristolochic acid nephropathy.
R. Jenkins, Luke C. Davies, P. Taylor, H. Akiyama +6 more
2014American Journal of Pathology50 citations Open access
Semantic Scholar
A urinary microRNA panel that is an early predictive biomarker of delayed graft function following kidney transplantation
U. Khalid, L. Newbury, Kate Simpson, R. Jenkins +5 more
2019Scientific Reports47 citations Open access
Semantic Scholar
Stabilization of Urinary MicroRNAs by Association with Exosomes and Argonaute 2 Protein
C. Beltrami, A. Clayton, L. Newbury, P. Corish +4 more
2015Non-Coding RNA47 citations Open access
Semantic Scholar
Transforming growth factor β1 represses proximal tubular cell microRNA-192 expression through decreased hepatocyte nuclear factor DNA binding.
R. Jenkins, John Martin, A. Phillips, Timothy Bowen +1 more
2012Biochemical Journal47 citations
Semantic Scholar
Analysis of urinary microRNAs in chronic kidney disease.
C. Beltrami, A. Clayton, A. Phillips, D. Fraser +1 more
2012Biochemical Society Transactions45 citations
Semantic Scholar
Targeting Toll-like receptors with soluble Toll-like receptor 2 prevents peritoneal dialysis solution-induced fibrosis.
A. Raby, G. Gónzalez-Mateo, Aled Williams, N. Topley +3 more
2018Kidney International42 citations Open access
Semantic Scholar
A Conserved Stem Loop Motif in the 5′Untranslated Region Regulates Transforming Growth Factor-β1 Translation
R. Jenkins, Rasha Bennagi, John Martin, A. Phillips +2 more
2010PLoS ONE41 citations Open access
Semantic Scholar
miR-21 Promotes Fibrogenesis in Peritoneal Dialysis.
Melisa Lopez-Anton, M. Lambie, M. López-Cabrera, C. Schmitt +10 more
2017American Journal of Pathology39 citations Open access
Semantic Scholar
MicroRNAs and Their Delivery in Diabetic Fibrosis.
Alexa Wonnacott, L. Denby, Richard Jm Coward, D. Fraser +1 more
2021Advanced Drug Delivery Reviews38 citations Open access
Semantic Scholar
ERK, p38, and Smad signaling pathways differentially regulate transforming growth factor-beta1 autoinduction in proximal tubular epithelial cells.
M. Zhang, D. Fraser, A. Phillips
2006American Journal of Pathology35 citations Open access
Semantic Scholar
Neutrophil-derived miR-223 as local biomarker of bacterial peritonitis
Amy C. Brook, R. Jenkins, A. Clayton, A. Kift-Morgan +8 more
2019Scientific Reports34 citations Open access
Semantic Scholar
Pleiotropy of microRNA-192 in the kidney.
R. Jenkins, John Martin, A. Phillips, Timothy Bowen +1 more
2012Biochemical Society Transactions34 citations
Semantic Scholar
Control of neutrophil influx during peritonitis by transcriptional cross‐regulation of chemokine CXCL1 by IL‐17 and IFN‐γ
R. Catar, Lei Chen, S. Cuff, A. Kift-Morgan +15 more
2020Journal of Pathology26 citations Open access
Semantic Scholar
MicroRNA‐21 (miR‐21) expression in hypothermic machine perfusate may be predictive of early outcomes in kidney transplantation
U. Khalid, E. Ablorsu, L. Szabo, R. Jenkins +3 more
2016Clinical Transplantation26 citations
Semantic Scholar
Acute kidney injury: a paradigm for miRNA regulation of the cell cycle.
U. Khalid, Timothy Bowen, D. Fraser, R. Jenkins
2014Biochemical Society Transactions25 citations
Semantic Scholar
An unexpected and serious complication of treatment with the atypical antipsychotic drug clozapine.
D. Fraser, M. Jibani
2000Clinical Nephrology25 citations
Semantic Scholar
IL-17A as a Potential Therapeutic Target for Patients on Peritoneal Dialysis
Vanessa Marchant, Antonio Tejera-Muñoz, L. Márquez-Expósito, S. Rayego‐Mateos +10 more
2020Biomolecules18 citations Open access
Semantic Scholar
The Systemic Microcirculation In Dialysis Populations.
Jennifer Williams, M. Gilchrist, D. Strain, D. Fraser +1 more
2020Microcirculation18 citations Open access
Semantic Scholar
MicroRNAs as biomarkers in chronic kidney disease
Alexa Wonnacott, Timothy Bowen, D. Fraser
2017Current opinion in nephrology and hypertension18 citations Open access
Semantic Scholar
A Localized Ischemic Preconditioning Regimen Increases Tumor Necrosis Factor α Expression in a Rat Model of Kidney Ischemia-Reperfusion Injury.
U. Khalid, R. Jenkins, G. Pino-Chavez, Timothy Bowen +2 more
2015Experimental and Clinical Transplantation17 citations
Semantic Scholar
Polarity of Response to Transforming Growth Factor-β1 in Proximal Tubular Epithelial Cells Is Regulated by β-Catenin*
Mei Zhang, Chien-Hung Lee, D. Luo, A. Krupa +2 more
2007Journal of Biological Chemistry16 citations Open access
Semantic Scholar
BMP-6 emerges as a potential major regulator of fibrosis in the kidney.
R. Jenkins, D. Fraser
2011American Journal of Pathology14 citations Open access
Semantic Scholar
miR-141 mediates recovery from acute kidney injury
L. Newbury, Kate Simpson, U. Khalid, Imogen John +7 more
2021Scientific Reports12 citations Open access
Semantic Scholar
Biogenesis, Stabilization, and Transport of microRNAs in Kidney Health and Disease
M. Thomas, D. Fraser, Timothy Bowen
2018Non-Coding RNA10 citations Open access
Semantic Scholar

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R. Jenkins×19
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A. Phillips×18
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A. Kift-Morgan×7

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