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A. Kloos · SciRah

Researcher profile · Semantic Scholar

A. Kloos

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A. Kloos — researcher profile on SciRah

h-index: 21
Works: 64
Citations: 1,444

Most-cited papers

Measurable residual disease (MRD) monitoring by next-generation sequencing before allogeneic hematopoietic cell transplantation in AML
F. Thol, R. Gabdoulline, Alessandro Liebich, P. Klement +29 more
2018Blood275 citations Open access
Semantic Scholar
Viral Infection of Tumors Overcomes Resistance to PD-1-immunotherapy by Broadening Neoantigenome-directed T-cell Responses.
N. Woller, E. Gürlevik, B. Fleischmann-Mundt, A. Schumacher +8 more
2015Molecular Therapy193 citations Open access
Semantic Scholar
Posttransplantation MRD monitoring in patients with AML by next-generation sequencing using DTA and non-DTA mutations.
M. Heuser, B. Heida, K. Büttner, C. Wienecke +24 more
2021Blood Advances105 citations Open access
Semantic Scholar
Administration of Gemcitabine After Pancreatic Tumor Resection in Mice Induces an Antitumor Immune Response Mediated by Natural Killer Cells.
E. Gürlevik, B. Fleischmann-Mundt, J. Brooks, I. Demir +18 more
2016Gastroenterology81 citations Open access
Semantic Scholar
Scalable generation of functional human iPSC-derived CAR-macrophages that efficiently eradicate CD19-positive leukemia
S. Abdin, Daniela Paasch, A. Kloos, M. C. Oliveira +12 more
2023Journal for ImmunoTherapy of Cancer72 citations Open access
Semantic Scholar
Antitumoural immunity by virus-mediated immunogenic apoptosis inhibits metastatic growth of hepatocellular carcinoma
B. Boozari, B. Mundt, N. Woller, N. Strüver +8 more
2010Gut65 citations
Semantic Scholar
Molecular retargeting of antibodies converts immune defense against oncolytic viruses into cancer immunotherapy
Julia Niemann, N. Woller, J. Brooks, B. Fleischmann-Mundt +9 more
2019Nature Communications62 citations Open access
Semantic Scholar
Prognostic effect of calreticulin mutations in patients with myelofibrosis after allogeneic hematopoietic stem cell transplantation
V. Panagiota, F. Thol, B. Markus, B. Fehse +21 more
2014Leukemia62 citations
Semantic Scholar
Acute myeloid leukemia derived from lympho-myeloid clonal hematopoiesis
F. Thol, Sabrina Klesse, L. Köhler, R. Gabdoulline +25 more
2016Leukemia53 citations Open access
Semantic Scholar
Virus-induced tumor inflammation facilitates effective DC cancer immunotherapy in a Treg-dependent manner in mice.
N. Woller, Sarah Knocke, B. Mundt, E. Gürlevik +11 more
2011Journal of Clinical Investigation53 citations Open access
Semantic Scholar
Preclinical Assessment of Suitable Natural Killer Cell Sources for Chimeric Antigen Receptor Natural Killer–Based “Off-the-Shelf” Acute Myeloid Leukemia Immunotherapies
S. Kloess, O. Oberschmidt, Julia Dahlke, Xuan-Khang Vu +11 more
2019Human Gene Therapy46 citations
Semantic Scholar
Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in Acute Myeloid Leukemia
Sagarajit Mohanty, N. Jyotsana, Amit Sharma, A. Kloos +13 more
2020Cancers40 citations Open access
Semantic Scholar
Clinical Implications and Dynamics of Clonal Hematopoiesis in Anti-CD19 CAR T-cell Treated Patients
V. Panagiota, Johanna Franziska Kerschbaum, O. Penack, Catarina M Stein +24 more
2023HemaSphere35 citations Open access
Semantic Scholar
Adjuvant gemcitabine therapy improves survival in a locally induced, R0‐resectable model of metastatic intrahepatic cholangiocarcinoma
E. Gürlevik, B. Fleischmann-Mundt, Nina Armbrecht, T. Longerich +9 more
2013Hepatology34 citations Open access
Semantic Scholar
Improved Activity against Acute Myeloid Leukemia with Chimeric Antigen Receptor (CAR)-NK-92 Cells Designed to Target CD123
M. Morgan, A. Kloos, Daniela Lenz, Nadine Kattre +8 more
2021Viruses32 citations Open access
Semantic Scholar
An optimized lentiviral vector system for conditional RNAi and efficient cloning of microRNA embedded short hairpin RNA libraries.
F. Adams, D. Heckl, Thomas Hoffmann, S. Talbot +6 more
2017Biomaterials28 citations Open access
Semantic Scholar
Optimized induction of mitochondrial apoptosis for chemotherapy-free treatment of BCR-ABL+acute lymphoblastic leukemia
M. Scherr, Hanna Kirchhoff, K. Battmer, K. Wohlan +10 more
2018Leukemia25 citations Open access
Semantic Scholar
Selectivity of oncolytic viral replication prevents antiviral immune response and toxicity, but does not improve antitumoral immunity.
E. Gürlevik, N. Woller, N. Strüver, P. Schache +5 more
2010Molecular Therapy24 citations Open access
Semantic Scholar
Fludarabine, cytarabine, and idarubicin with or without venetoclax in patients with relapsed/refractory acute myeloid leukemia
R. Shahswar, G. Beutel, R. Gabdoulline, A. Schwarzer +16 more
2023Haematologica23 citations Open access
Semantic Scholar
PolySia-Specific Retargeting of Oncolytic Viruses Triggers Tumor-Specific Immune Responses and Facilitates Therapy of Disseminated Lung Cancer
A. Kloos, N. Woller, E. Gürlevik, C. Ureche +7 more
2015Cancer immunology research23 citations Open access
Semantic Scholar
In vivo efficacy of mutant IDH1 inhibitor HMS-101 and structural resolution of distinct binding site
A. Chaturvedi, Ramya Goparaju, C. Gupta, J. Weder +13 more
2019Leukemia21 citations Open access
Semantic Scholar
Effective drug treatment identified by in vivo screening in a transplantable patient-derived xenograft model of chronic myelomonocytic leukemia
A. Kloos, Konstantinos Mintzas, Lina Winckler, R. Gabdoulline +15 more
2020Leukemia12 citations Open access
Semantic Scholar
A 19‐color single‐tube full spectrum flow cytometry assay for the detection of measurable residual disease in acute myeloid leukemia
H. Fokken, Julian Waclawski, Nadine Kattre, A. Kloos +6 more
2023Cytometry Part A10 citations Open access
Semantic Scholar
XPO1-dependency of DEK::NUP214 leukemia
Fiorella Charles Cano, A. Kloos, Rucha Y Hebalkar, Thomas Plenge +10 more
2025Leukemia9 citations Open access
Semantic Scholar
Retargeted oncolytic viruses provoke tumor-directed T-cell responses
A. Kloos, N. Woller, R. Gerardy-Schahn, F. Kühnel
2015Oncoimmunology9 citations Open access
Semantic Scholar
A Novel Inhibitor of Mutant IDH1 Induces Differentiation in Vivo and Prolongs Survival in a Mouse Model of Leukemia
A. Chaturvedi, Michelle Maria Araujo Cruz, Ramya Goparaju, N. Jyotsana +10 more
20148 citations
Semantic Scholar
Frequency and Clinical Characteristics Associated with Putative CAR Targets ADGRE2, CCR1, CD70, and LILRB2 in Acute Myeloid Leukemia
R. Shahswar, A. Kloos, R. Gabdoulline, Sagarajit Mohanty +18 more
2018Blood6 citations
Semantic Scholar
Meganuclease-mediated virus self-cleavage facilitates tumor-specific virus replication.
E. Gürlevik, P. Schache, A. Goez, A. Kloos +5 more
2013Molecular Therapy6 citations Open access
Semantic Scholar
Base edited “universal” donor CAR T-cell strategies for acute myeloid leukaemia
Renuka Kadirkamanathan, C. Georgiadis, A. Kloos, Akshay Joshi +7 more
2025Leukemia5 citations Open access
Semantic Scholar
Base edited “universal” donor CAR T cell strategies for acute myeloid leukaemia
Renuka Kadirkamanathan, C. Georgiadis, A. Kloos, Annie Etuk +6 more
2024bioRxiv5 citations Open access
Semantic Scholar
Single and Combinational Multiplex Base-Edited 'Universal' CAR T Cells in a Humanised Model of Primary CD7+CD33+ AML
A. Kloos, C. Georgiadis, Annie Etuk, S. A. Gkazi +11 more
2022Blood5 citations
Semantic Scholar
Fla-IDA Chemotherapy with or without Venetoclax in Patients with Relapsed/Refractory Acute Myeloid Leukemia
R. Shahswar, G. Beutel, R. Gabdoulline, A. Schwarzer +17 more
2022Blood4 citations Open access
Semantic Scholar
Allogeneic, CD34 +, Umbilical Cordblood-Derived NK Cell Adoptive Immunotherapy for the Treatment of Acute Myeloid Leukemia Patients with Measurable Residual Disease
M. Heuser, A. Tschan-Plessl, F. Thol, A. Schwarzer +5 more
2021Blood4 citations Open access
Semantic Scholar
Prognostic Impact of Subclinical FLT3-ITD Microclones in Patients with Acute Myeloid Leukemia
Paul Olson, R. Gabdoulline, R. Shahswar, A. Kloos +14 more
2024Blood3 citations Open access
Semantic Scholar
Post Transplantation Measurable Residual Disease (MRD) Monitoring Using Next-Generation Sequencing Is Highly Predictive for Relapseafter Allogeneic Stem Cell Transplantation
F. Thol, B. Heida, Konstatin Buettner, C. Wienecke +23 more
2019Blood3 citations
Semantic Scholar
Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in AML
Sagarajit Mohanty, N. Jyotsana, Amit Sharma, Basem Othman +8 more
2019Blood3 citations Open access
Semantic Scholar
Lymphotoxin alpha eradicates acute myeloid leukemia and simultaneously promotes healthy hematopoiesis in mice.
Ulrike Höckendorf, S. Dutta, A. Kloos, M. Runtsch +32 more
2025Science Translational Medicine2 citations
Semantic Scholar
Measurable residual disease (MRD) monitoring by next-generation sequencing before allogeneic hematopoietic cell transplantation in AML
F. Thol, R. Gabdoulline, Alessandro Liebich, P. Klement +20 more
20212 citations
Semantic Scholar
Unleashing intrinsic inflammation in AML using therapeutic cytokines overcomes pro-survival pathways and induces deep and durable remission In Vivo.
U. Hoeckendorf, S. Dutta, A. Kloos, M. Runtsch +20 more
2025Blood1 citations
Semantic Scholar
Characterizing Secondary-Site Mutations in Isocitrate-Dehydrogenase-1 (IDH1)
Jyoti Kandarp, A. Kloos, K. Goerlich, Nadine Kattre +2 more
2024Blood1 citations
Semantic Scholar
P1456: EARLY SAFETY AND CLINICAL COURSE OF PATIENTS WITH ACUTE MYELOID LEUKEMIA AND MEASURABLE RESIDUAL DISEASE RECEIVING GTA002, AN OFF-THE-SHELF, EX VIVO-CULTURED ALLOGENEIC NK CELL PREPARATION
M. Heuser, W. Fiedler, A. Block, D. D. de Leeuw +9 more
2022HemaSphere1 citations Open access
Semantic Scholar
Abstract 3984: Lymphotoxin alpha induces myeloid differentiation and programmed cell death in myeloid leukemic stem cells resulting in deep and sustained remission in vivo
Philipp J. Jost, Ulrike Höckendorf, S. Dutta, A. Kloos +32 more
2026Cancer Research0 citations
Semantic Scholar
Rapid and reproducible karyotyping with long-read sequencing in patients with AML
Michael Heuser, A. Dolnik, Isabell Arnhardt, Courteney K. Lai +21 more
2026Blood Advances0 citations Open access
Semantic Scholar
A platform of serially transplantable AML PDX models covering subgroups for which no cell lines exist
B. Vick, V. Jurinovic, Kristina Kuhbandner, Lena Lagally +42 more
2026HemaSphere0 citations Open access
Semantic Scholar
Umbilical cord blood CD34+ hematopoietic stem cell-derived natural killer cells in Acute Myeloid Leukemia – a phase I clinical study
M. Heuser, Anna-Maria Georgoudaki, Adrian Schwarzer, A. Kloos +19 more
2025Blood0 citations
Semantic Scholar
P1278: MEASURABLE RESIDUAL DISEASE ASSESSMENT IN THE PROSPECTIVE HAPLOMUD STUDY
Isabell Arnhardt, A. Kloos, Nadine Kattre, R. Gabdoulline +19 more
2023HemaSphere0 citations Open access
Semantic Scholar
P394: INSIGHTS INTO PATIENT-DERIVED XENOGRAFT MODELS FOR DEK-NUP214 LEUKEMIA
F. C. Cano, A. Kloos, T. Fangmann, N. Kattre +4 more
2022HemaSphere0 citations Open access
Semantic Scholar
P401: NEXT-GENERATION FLOW CYTOMETRY TO DETECT MEASURABLE RESIDUAL DISEASE IN ACUTE MYELOID LEUKEMIA USING A 19-COLOR FULL SPECTRUM FLOW CYTOMETRY PANEL
H. Fokken, N. Kattre, A. Kloos, M. Heuser +3 more
2022HemaSphere0 citations Open access
Semantic Scholar
DEK-NUP214 Acute Myeloid Leukemia Depends on CRM1 In Vivo
Fiorella Charles Cano, A. Kloos, Rucha Y Hebalkar, R. Gabdoulline +6 more
2022Blood0 citations Open access
Semantic Scholar
Correction: Effective drug treatment identified by in vivo screening in a transplantable patient-derived xenograft model of chronic myelomonocytic leukemia
A. Kloos, Konstantinos Mintzas, Lina Winckler, R. Gabdoulline +15 more
2021Leukemia0 citations Open access
Semantic Scholar

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