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M. Heikinheimo · SciRah

Researcher profile · Semantic Scholar

M. Heikinheimo

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M. Heikinheimo — researcher profile on SciRah

h-index: 52
Works: 214
Citations: 8,469

Most-cited papers

Role of the GATA family of transcription factors in endocrine development, function, and disease.
R. Viger, Séverine Mazaud Guittot, M. Anttonen, D. Wilson +1 more
2008Molecular Endocrinology273 citations Open access
Semantic Scholar
The FOXL2 C134W mutation is characteristic of adult granulosa cell tumors of the ovary
Stacey Jamieson, R. Bützow, N. Andersson, M. Alexiadis +4 more
2010Modern Pathology223 citations Open access
Semantic Scholar
Single cell transcriptomic analysis of murine lung development on hyperoxia-induced damage
M. Hurskainen, I. Mižíková, David P. Cook, N. Andersson +8 more
2021Nature Communications176 citations Open access
Semantic Scholar
GATA4 regulates Sertoli cell function and fertility in adult male mice
A. Kyrönlahti, Rosemarie Euler, M. Bielińska, E. Schoeller +4 more
2010Molecular and Cellular Endocrinology124 citations Open access
Semantic Scholar
Adrenocortical Zonation, Renewal, and Remodeling
M. Pihlajoki, Julia Dörner, Rebecca S. Cochran, M. Heikinheimo +1 more
2015Frontiers in Endocrinology106 citations Open access
Semantic Scholar
Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa
H. Haveri, M. Westerholm-Ormio, K. Lindfors, M. Mäki +3 more
2008BMC Gastroenterology99 citations Open access
Semantic Scholar
Pathogenesis and treatment of adult-type granulosa cell tumor of the ovary
A. Färkkilä, Ulla-Maija Haltia, J. Tapper, M. McConechy +2 more
2017Annals medicus88 citations Open access
Semantic Scholar
Molecularly Defined Adult Granulosa Cell Tumor of the Ovary: The Clinical Phenotype.
M. McConechy, A. Färkkilä, H. M. Horlings, A. Talhouk +22 more
2016Journal of the National Cancer Institute72 citations Open access
Semantic Scholar
The clinical utility of serum anti‐Müllerian hormone in the follow‐up of ovarian adult‐type granulosa cell tumors—A comparative study with inhibin B
A. Färkkilä, Sanna Koskela, S. Bryk, H. Alfthan +7 more
2015International Journal of Cancer71 citations Open access
Semantic Scholar
GATA-4 regulates Bcl-2 expression in ovarian granulosa cell tumors.
A. Kyrönlahti, Maarit Rämö, M. Tamminen, L. Unkila-Kallio +7 more
2008Endocrinology71 citations Open access
Semantic Scholar
Clinical Characteristics and Survival of Patients With an Adult-Type Ovarian Granulosa Cell Tumor: A 56-Year Single-Center Experience
S. Bryk, A. Färkkilä, R. Bützow, A. Leminen +4 more
2015International Journal of Gynecologic Cancer69 citations Open access
Semantic Scholar
Origin and Molecular Pathology of Adrenocortical Neoplasms
M. Bielińska, H. Parviainen, S. Kiiveri, M. Heikinheimo +1 more
2009Veterinary Pathology-Supplement62 citations Open access
Semantic Scholar
GATA4 Regulates Blood-Testis Barrier Function and Lactate Metabolism in Mouse Sertoli Cells.
Anja Schrade, A. Kyrönlahti, O. Akinrinade, M. Pihlajoki +7 more
2016Endocrinology61 citations Open access
Semantic Scholar
GATA4 Deficiency Impairs Ovarian Function in Adult Mice1
A. Kyrönlahti, M. Vetter, Rosemarie Euler, M. Bielińska +4 more
2011Biology of Reproduction61 citations Open access
Semantic Scholar
FOXL2, GATA4, and SMAD3 Co-Operatively Modulate Gene Expression, Cell Viability and Apoptosis in Ovarian Granulosa Cell Tumor Cells
M. Anttonen, M. Pihlajoki, N. Andersson, A. Georges +6 more
2014PLoS ONE60 citations Open access
Semantic Scholar
Transcription factor GATA-6 is expressed in quiescent myofibroblasts in idiopathic pulmonary fibrosis.
O. Leppäranta, V. Pulkkinen, K. Koli, Riika Vähätalo +4 more
2010American Journal of Respiratory Cell and Molecular Biology59 citations
Semantic Scholar
Adult ovarian granulosa cell tumor transcriptomics: prevalence of FOXL2 target genes misregulation gives insights into the pathogenic mechanism of the p.Cys134Trp somatic mutation
B. Benayoun, M. Anttonen, D. L'hôte, M. Bailly-Bechet +3 more
2013Oncogene56 citations
Semantic Scholar
Anti-Müllerian hormone inhibits growth of AMH type II receptor-positive human ovarian granulosa cell tumor cells by activating apoptosis
M. Anttonen, A. Färkkilä, Hanna Tauriala, M. Kauppinen +4 more
2011Laboratory Investigation53 citations Open access
Semantic Scholar
WNT4 is expressed in human fetal and adult ovaries and its signaling contributes to ovarian cell survival.
M. Jääskeläinen, R. Prunskaite-Hyyryläinen, Florence Naillat, H. Parviainen +7 more
2010Molecular and Cellular Endocrinology53 citations
Semantic Scholar
Characteristics and outcome of recurrence in molecularly defined adult-type ovarian granulosa cell tumors.
S. Bryk, A. Färkkilä, R. Bützow, A. Leminen +4 more
2016Gynecologic Oncology50 citations
Semantic Scholar
Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice.
M. Pihlajoki, Elisabeth Gretzinger, Rebecca S. Cochran, A. Kyrönlahti +8 more
2013Endocrinology50 citations Open access
Semantic Scholar
High Prevalence of Sacrococcygeal Teratoma in Finland – A Nationwide Population‐Based Study
Satu-Liisa K. Pauniaho, O. Heikinheimo, K. Vettenranta, Jonna Salonen +4 more
2013Acta paediatrica48 citations
Semantic Scholar
GATA4 is a key regulator of steroidogenesis and glycolysis in mouse Leydig cells.
Anja Schrade, A. Kyrönlahti, O. Akinrinade, M. Pihlajoki +7 more
2015Endocrinology47 citations Open access
Semantic Scholar
Vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 are highly expressed in ovarian granulosa cell tumors.
A. Färkkilä, M. Anttonen, Jurate Pociuviene, A. Leminen +3 more
2011European Journal of Endocrinology42 citations Open access
Semantic Scholar
GATA4 protects granulosa cell tumors from TRAIL-induced apoptosis.
A. Kyrönlahti, M. Kauppinen, E. Lind, L. Unkila-Kallio +5 more
2010Endocrine-Related Cancer41 citations Open access
Semantic Scholar
High survival rates after liver transplantation for hepatoblastoma and hepatocellular carcinoma
S. Kosola, Jouni Lauronen, H. Sairanen, M. Heikinheimo +2 more
2010Pediatric Transplantation39 citations
Semantic Scholar
The incidences of malignant gonadal and extragonadal germ cell tumors in males and females: a population-based study covering over 40 years in Finland
Satu-Liisa K. Pauniaho, Jonna Salonen, M. Helminen, K. Vettenranta +2 more
2012Cancer Causes and Control38 citations
Semantic Scholar
Serum FGF19 predicts outcomes of Kasai portoenterostomy in biliary atresia
I. Nyholm, M. Hukkinen, M. Pihlajoki, J. Davidson +10 more
2023Hepatology34 citations Open access
Semantic Scholar
HER2 and GATA4 are new prognostic factors for early-stage ovarian granulosa cell tumor—a long-term follow-up study
A. Färkkilä, N. Andersson, R. Bützow, A. Leminen +3 more
2014Cancer Medicine34 citations Open access
Semantic Scholar
Serum vascular endothelial growth factor A (VEGF) is elevated in patients with ovarian granulosa cell tumor (GCT), and VEGF inhibition by bevacizumab induces apoptosis in GCT in vitro.
A. Färkkilä, M. Pihlajoki, Hanna Tauriala, R. Bützow +4 more
2011Journal of Clinical Endocrinology and Metabolism33 citations
Semantic Scholar
Tumor markers AFP, CA 125, and CA 19-9 in the long-term follow-up of sacrococcygeal teratomas in infancy and childhood
Satu-Liisa K. Pauniaho, Olga Tatti, P. Lahdenne, H. Lindahl +3 more
2010Tumor Biology32 citations
Semantic Scholar
Systematic drug sensitivity testing reveals synergistic growth inhibition by dasatinib or mTOR inhibitors with paclitaxel in ovarian granulosa cell tumor cells.
Ulla-Maija Haltia, N. Andersson, B. Yadav, A. Färkkilä +12 more
2017Gynecologic Oncology31 citations
Semantic Scholar
Regulation of cell death in human fetal and adult ovaries--role of Bok and Bcl-X(L).
M. Jääskeläinen, Anni I. Nieminen, Reeta-Maria Pökkylä, M. Kauppinen +5 more
2010Molecular and Cellular Endocrinology31 citations Open access
Semantic Scholar
Novel markers of gonadectomy-induced adrenocortical neoplasia in the mouse and ferret
Maximiliaan Schillebeeckx, M. Pihlajoki, Elisabeth Gretzinger, Wei Yang +10 more
2014Molecular and Cellular Endocrinology28 citations Open access
Semantic Scholar
GATA4 is a critical regulator of gonadectomy-induced adrenocortical tumorigenesis in mice.
Justyna Krachulec, M. Vetter, Anja Schrade, Ann-Kathrin Löbs +8 more
2012Endocrinology28 citations Open access
Semantic Scholar
TRAIL pathway components and their putative role in granulosa cell apoptosis in the human ovary.
M. Jääskeläinen, A. Kyrönlahti, M. Anttonen, Y. Nishi +6 more
2009Differentiation; research in biological diversity26 citations
Semantic Scholar
Roles of human epididymis protein 4, carbohydrate antigen 125, inhibin B and anti-Müllerian hormone in the differential diagnosis and follow-up of ovarian granulosa cell tumors.
Ulla-Maija Haltia, M. Hallamaa, J. Tapper, J. Hynninen +7 more
2017Gynecologic Oncology25 citations Open access
Semantic Scholar
Expression of Wnt and TGF-β pathway components and key adrenal transcription factors in adrenocortical tumors – association to carcinoma aggressiveness
H. Parviainen, Anja Schrade, S. Kiiveri, R. Prunskaite-Hyyryläinen +5 more
2013Pathology, Research and Practice25 citations Open access
Semantic Scholar
SLC-0111, an inhibitor of carbonic anhydrase IX, attenuates hepatoblastoma cell viability and migration
K. Eloranta, M. Pihlajoki, Emmi Liljeström, Ruth Nousiainen +6 more
2023Frontiers in Oncology23 citations Open access
Semantic Scholar
GATA factors in endocrine neoplasia
M. Pihlajoki, A. Färkkilä, T. Soini, M. Heikinheimo +1 more
2015Molecular and Cellular Endocrinology23 citations Open access
Semantic Scholar
Chloroquine Triggers Cell Death and Inhibits PARPs in Cell Models of Aggressive Hepatoblastoma
K. Eloranta, S. Cairo, Emmi Liljeström, T. Soini +5 more
2020Frontiers in Oncology22 citations Open access
Semantic Scholar
Differential developmental expression of transcription factors GATA-4 and GATA-6, their cofactor FOG-2 and downstream target genes in testicular carcinoma in situ and germ cell tumors.
Jonna Salonen, Ewa Rajpert-De Meyts, S. Mannisto, J. Nielsen +3 more
2010European Journal of Endocrinology22 citations
Semantic Scholar
Prognostic and Pathophysiologic Significance of IL-8 (CXCL8) in Biliary Atresia
Nimish Godbole, I. Nyholm, M. Hukkinen, J. Davidson +10 more
2021Journal of Clinical Medicine21 citations Open access
Semantic Scholar
Functional Profiling of FSH and Estradiol in Ovarian Granulosa Cell Tumors
Ulla-Maija Haltia, M. Pihlajoki, N. Andersson, Lotta Mäkinen +11 more
2020Journal of the Endocrine Society21 citations Open access
Semantic Scholar
Transcription Factor GATA-4 Is Abundantly Expressed in Childhood but Not in Adult Liver Tumors
T. Soini, H. Haveri, Jenni M. Elo, M. Kauppinen +6 more
2012Journal of Pediatric Gastroenterology and Nutrition - JPGN21 citations Open access
Semantic Scholar
Downregulation of transcription factor GATA4 sensitizes human hepatoblastoma cells to doxorubicin-induced apoptosis
T. Soini, M. Pihlajoki, A. Kyrönlahti, L. Andersson +2 more
2017Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine20 citations Open access
Semantic Scholar
Transcription factor GATA6: a novel marker and putative inducer of ductal metaplasia in biliary atresia.
T. Soini, M. Pihlajoki, N. Andersson, J. Lohi +6 more
2018American Journal of Physiology - Gastrointestinal and Liver Physiology18 citations Open access
Semantic Scholar
Probing GATA factor function in mouse Leydig cells via testicular injection of adenoviral vectors
Gervette M. Penny, Rebecca B Cochran, M. Pihlajoki, A. Kyrönlahti +5 more
2017Reproduction18 citations Open access
Semantic Scholar
Transcription factor GATA4 associates with mesenchymal-like gene expression in human hepatoblastoma cells
T. Soini, K. Eloranta, M. Pihlajoki, A. Kyrönlahti +6 more
2018Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine17 citations Open access
Semantic Scholar
GLI1+ progenitor cells in the adrenal capsule of the adult mouse give rise to heterotopic gonadal-like tissue
Julia Dörner, V. M. Rodriguez, R. Ziegler, Theresa Röhrig +6 more
2016Molecular and Cellular Endocrinology17 citations Open access
Semantic Scholar

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D. Wilson×22
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D. Wilson — researcher profile on SciRah
M. Pihlajoki×19
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M. Pihlajoki — researcher profile on SciRah
M. Anttonen×18
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M. Anttonen — researcher profile on SciRah
L. Unkila-Kallio×15
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L. Unkila-Kallio — researcher profile on SciRah

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A. Kyrönlahti — researcher profile on SciRah

A. Färkkilä×14

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A. Färkkilä — researcher profile on SciRah

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R. Bützow — researcher profile on SciRah

N. Andersson×12

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N. Andersson — researcher profile on SciRah

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A. Leminen — researcher profile on SciRah

Anja Schrade×7

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Anja Schrade — researcher profile on SciRah

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T. Soini — researcher profile on SciRah

M. Pakarinen×6

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M. Pakarinen — researcher profile on SciRah