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G. Pavlakis · SciRah

Researcher profile · Semantic Scholar

G. Pavlakis

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G. Pavlakis — researcher profile on SciRah

h-index: 76
Works: 365
Citations: 20K

Most-cited papers

Efficient production and enhanced tumor delivery of engineered extracellular vesicles
Dionysios C. Watson, Defne Bayik, Avinash Srivatsan, C. Bergamaschi +11 more
2016Biomaterials356 citations Open access
Semantic Scholar
Labeling Extracellular Vesicles for Nanoscale Flow Cytometry
A. Morales-Kastresana, Bill Telford, Thomas Musich, K. McKinnon +13 more
2017Scientific Reports332 citations Open access
Semantic Scholar
Insights to SARS-CoV-2 life cycle, pathophysiology, and rationalized treatments that target COVID-19 clinical complications
I. Trougakos, K. Stamatelopoulos, E. Terpos, O. Tsitsilonis +5 more
2021Journal of Biomedical Sciences240 citations Open access
Semantic Scholar
Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients
C. Bergamaschi, E. Terpos, M. Rosati, M. Angel +11 more
2021Cell Reports223 citations Open access
Semantic Scholar
Scalable, cGMP-compatible purification of extracellular vesicles carrying bioactive human heterodimeric IL-15/lactadherin complexes
Dionysios C. Watson, Bryant C. Yung, C. Bergamaschi, B. Chowdhury +7 more
2018Journal of Extracellular Vesicles173 citations Open access
Semantic Scholar
Heterodimeric IL-15 delays tumor growth and promotes intratumoral CTL and dendritic cell accumulation by a cytokine network involving XCL1, IFN-γ, CXCL9 and CXCL10
C. Bergamaschi, Hrishikesh Pandit, Bethany A. Nagy, D. Stellas +7 more
2020Journal for ImmunoTherapy of Cancer126 citations Open access
Semantic Scholar
A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques
B. Mothe, Xin-Tao Hu, A. Llano, M. Rosati +17 more
2015Journal of Translational Medicine97 citations Open access
Semantic Scholar
HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition
M. Vaccari, S. Fourati, S. Gordon, Dallas R. Brown +29 more
2018Nature Medicine69 citations Open access
Semantic Scholar
Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes
Dionysios C. Watson, Eirini Moysi, A. Valentin, C. Bergamaschi +13 more
2018PLoS Pathogens68 citations Open access
Semantic Scholar
SARS-CoV-2 antibody kinetics eight months from COVID-19 onset: Persistence of spike antibodies but loss of neutralizing antibodies in 24% of convalescent plasma donors
E. Terpos, D. Stellas, M. Rosati, T. Sergentanis +13 more
2021European journal of internal medicine63 citations Open access
Semantic Scholar
Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge
B. Felber, Zhongyan Lu, Xin-Tao Hu, A. Valentin +33 more
2020Cell Reports54 citations Open access
Semantic Scholar
Accumulation of follicular CD8+ T cells in pathogenic SIV infection
S. Ferrando-Martínez, Eirini Moysi, A. Pegu, S. Andrews +11 more
2018Journal of Clinical Investigation52 citations Open access
Semantic Scholar
Heterodimeric IL-15 in Cancer Immunotherapy
C. Bergamaschi, Vasiliki Stravokefalou, D. Stellas, Sevasti Karaliota +2 more
2021Cancers46 citations Open access
Semantic Scholar
Correlates of HIV-1 control after combination immunotherapy
M. Peluso, D. Sandel, A. Deitchman, S. J. Kim +36 more
2025Nature44 citations Open access
Semantic Scholar
The Emerging Role of Convalescent Plasma in the Treatment of COVID-19
T. Psaltopoulou, T. Sergentanis, V. Pappa, M. Politou +4 more
2020HemaSphere44 citations Open access
Semantic Scholar
Phase I study of single agent NIZ985, a recombinant heterodimeric IL-15 agonist, in adult patients with metastatic or unresectable solid tumors
Kevin Conlon, Dionysios C. Watson, T. Waldmann, A. Valentin +18 more
2021Journal for ImmunoTherapy of Cancer42 citations Open access
Semantic Scholar
Comparison of Immunogenicity in Rhesus Macaques of Transmitted-Founder, HIV-1 Group M Consensus, and Trivalent Mosaic Envelope Vaccines Formulated as a DNA Prime, NYVAC, and Envelope Protein Boost
Sandrine L. Hulot, B. Korber, E. Giorgi, N. Vandergrift +26 more
2015Journal of Virology42 citations Open access
Semantic Scholar
Anti–SARS-CoV-2 Antibody Responses in Convalescent Plasma Donors Are Increased in Hospitalized Patients; Subanalyses of a Phase 2 Clinical Study
E. Terpos, M. Politou, T. Sergentanis, A. Mentis +29 more
2020Microorganisms41 citations Open access
Semantic Scholar
Sequential Analysis of Binding and Neutralizing Antibody in COVID-19 Convalescent Patients at 14 Months After SARS-CoV-2 Infection
M. Rosati, E. Terpos, I. Ntanasis-Stathopoulos, Mahesh Agarwal +9 more
2021Frontiers in Immunology38 citations Open access
Semantic Scholar
DNA Prime-Boost Vaccine Regimen To Increase Breadth, Magnitude, and Cytotoxicity of the Cellular Immune Responses to Subdominant Gag Epitopes of Simian Immunodeficiency Virus and HIV
Xin-Tao Hu, A. Valentin, F. Dayton, V. Kulkarni +10 more
2016Journal of Immunology38 citations Open access
Semantic Scholar
Towards a European strategy to address the COVID-19 pandemic
V. Priesemann, R. Balling, S. Bauer, P. Beutels +24 more
2021The Lancet37 citations Open access
Semantic Scholar
Control of Heterologous Simian Immunodeficiency Virus SIVsmE660 Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques
Shakti Singh, E. Ramírez-Salazar, Rami Doueiri, A. Valentin +27 more
2018Journal of Virology36 citations Open access
Semantic Scholar
Heterodimeric IL-15 Treatment Enhances Tumor Infiltration, Persistence and Effector Functions of Adoptively Transferred Tumor-specific T Cells in the Absence of Lymphodepletion
S. Ng, Bethany A. Nagy, S. Jensen, Xin-Tao Hu +5 more
2016Clinical Cancer Research33 citations Open access
Semantic Scholar
Comparative immunogenicity of an mRNA/LNP and a DNA vaccine targeting HIV gag conserved elements in macaques
A. Valentin, C. Bergamaschi, M. Rosati, M. Angel +11 more
2022Frontiers in Immunology29 citations Open access
Semantic Scholar
Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy
F. Barrenäs, Scott G. Hansen, Lynn Law, Connor B. Driscoll +34 more
2021PLoS Pathogens29 citations Open access
Semantic Scholar
Neutrophil vaccination dynamics and their capacity to mediate B-cell help in Rhesus Macaques
Thomas Musich, M. A. Rahman, V. Mohanram, Leia K. Miller-Novak +6 more
2018Journal of Immunology28 citations Open access
Semantic Scholar
Rapid transient and longer-lasting innate cytokine changes associated with adaptive immunity after repeated SARS-CoV-2 BNT162b2 mRNA vaccinations
M. Rosati, E. Terpos, Philip Homan, C. Bergamaschi +10 more
2023Frontiers in Immunology27 citations Open access
Semantic Scholar
Therapeutic conserved elements (CE) DNA vaccine induces strong T-cell responses against highly conserved viral sequences during simian-human immunodeficiency virus infection
P. Munson, Yi Liu, Debra L Bratt, J. Fuller +5 more
2018Human Vaccines & Immunotherapeutics27 citations Open access
Semantic Scholar
Optimized administration of hetIL-15 expands lymphocytes and minimizes toxicity in rhesus macaques
C. Bergamaschi, Dionysios C. Watson, A. Valentin, Jenifer Bear +4 more
2018Cytokine27 citations Open access
Semantic Scholar
The benefits, costs and feasibility of a low incidence COVID-19 strategy
T. Czypionka, Emil N. Iftekhar, Barbara Prainsack, V. Priesemann +19 more
2022The Lancet Regional Health - Europe25 citations Open access
Semantic Scholar
Heterodimeric IL-15 (hetIL-15) reduces circulating tumor cells and metastasis formation improving chemotherapy and surgery in 4T1 mouse model of TNBC
Vasiliki Stravokefalou, D. Stellas, Sevasti Karaliota, Bethany A. Nagy +4 more
2023Frontiers in Immunology23 citations Open access
Semantic Scholar
Anti-V2 antibodies virus vulnerability revealed by envelope V1 deletion in HIV vaccine candidates
Isabela Silva de Castro, Giacomo Gorini, R. Mason, J. Gorman +54 more
2020iScience23 citations Open access
Semantic Scholar
IL-15/IL-15Rα/CD80-expressing AML cell vaccines eradicate minimal residual disease in leukemic mice.
Yi-Min Shi, Lillia Dincheva-Vogel, Charles E Ayemoba, Jeffrey P. Fung +4 more
2018Blood Advances22 citations Open access
Semantic Scholar
HIV Env conserved element DNA vaccine alters immunodominance in macaques
Xin-Tao Hu, A. Valentin, M. Rosati, Siriphan Manocheewa +9 more
2017Human Vaccines & Immunotherapeutics21 citations Open access
Semantic Scholar
Step-dose IL-7 treatment promotes systemic expansion of T cells and alters immune cell landscape in blood and lymph nodes
Hrishikesh Pandit, A. Valentin, M. Angel, C. Deleage +5 more
2023iScience17 citations Open access
Semantic Scholar
The Brighton Collaboration standardized template for collection of key information for benefit-risk assessment of nucleic acid (RNA and DNA) vaccines
Denny Kim, J. Robertson, J. Excler, R. Condit +9 more
2020Vaccine17 citations Open access
Semantic Scholar
Reduced Antibodies and Innate Cytokine Changes in SARS-CoV-2 BNT162b2 mRNA Vaccinated Transplant Patients With Hematological Malignancies
C. Bergamaschi, M. Pagoni, M. Rosati, M. Angel +13 more
2022Frontiers in Immunology16 citations Open access
Semantic Scholar
DNA is an efficient booster of dendritic cell-based vaccine
Jin-Yao Li, A. Valentin, R. K. Beach, C. Alicea +2 more
2015Human Vaccines & Immunotherapeutics16 citations Open access
Semantic Scholar
Control of SARS-CoV-2 infection after Spike DNA or Spike DNA+Protein co-immunization in rhesus macaques
M. Rosati, M. Agarwal, Xin-Tao Hu, Santhi Devasundaram +15 more
2021bioRxiv15 citations Open access
Semantic Scholar
Gag and env conserved element CE DNA vaccines elicit broad cytotoxic T cell responses targeting subdominant epitopes of HIV and SIV Able to recognize virus-infected cells in macaques
Xin-Tao Hu, Zhongyan Lu, A. Valentin, M. Rosati +6 more
2018Human Vaccines & Immunotherapeutics15 citations Open access
Semantic Scholar
Early T Follicular Helper Cell Responses and Germinal Center Reactions Are Associated with Viremia Control in Immunized Rhesus Macaques
Sabrina Helmold Hait, Diego A. Vargas-Inchaustegui, Thomas Musich, V. Mohanram +9 more
2018Journal of Virology15 citations Open access
Semantic Scholar
XBB.1.5 neutralizing antibodies upon bivalent COVID-19 vaccination are similar to XBB but lower than BQ.1.1
Santhi Devasundaram, E. Terpos, M. Rosati, I. Ntanasis-Stathopoulos +8 more
2023American journal of hematology/oncology14 citations Open access
Semantic Scholar
Low Spike Antibody Levels and Impaired BA.4/5 Neutralization in Patients with Multiple Myeloma or Waldenstrom’s Macroglobulinemia after BNT162b2 Booster Vaccination
M. Rosati, E. Terpos, Jenifer Bear, R. Burns +7 more
2022Cancers14 citations Open access
Semantic Scholar
A new step towards an HIV/AIDS vaccine.
G. Pavlakis, B. Felber
2018The Lancet14 citations
Semantic Scholar
Evaluation of chimeric antigen receptor T cell therapy in non-human primates infected with SHIV or SIV
N. Iwamoto, B. Patel, Kai-Mei Song, R. Mason +5 more
2021PLoS ONE13 citations Open access
Semantic Scholar
A Phase II Study on the Use of Convalescent Plasma for the Treatment of Severe COVID-19- A Propensity Score-Matched Control Analysis
V. Pappa, A. Bouchla, E. Terpos, T. Thomopoulos +26 more
2021Microorganisms13 citations Open access
Semantic Scholar
Distinct Neutralization Profile of Spike Variants by Antibodies Induced upon SARS-CoV-2 Infection or Vaccination
M. Rosati, E. Terpos, M. Agarwal, V. Karalis +9 more
2021American journal of hematology/oncology13 citations Open access
Semantic Scholar
The Immunogenicity of an HIV-1 Gag Conserved Element DNA Vaccine in People with HIV and Receiving Antiretroviral Therapy
Jeffrey M. Jacobson, B. Felber, Hui-Chao Chen, G. Pavlakis +21 more
2023AIDS (London)12 citations
Semantic Scholar
Temporal Dominance of B.1.1.7 over B.1.354 SARS-CoV-2 Variant: A Hypothesis Based on Areas of Variant Co-Circulation
E. Kostaki, Ioulia K. Tseti, S. Tsiodras, G. Pavlakis +2 more
2021Life12 citations Open access
Semantic Scholar
Delineating the SARS-CoV-2 Induced Interplay between the Host Immune System and the DNA Damage Response Network
C. Papanikolaou, V. Rapti, D. Stellas, D. Stefanou +3 more
2022Vaccines11 citations Open access
Semantic Scholar

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