Rebecca J. Griffin

Most-cited papers

1. Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling.

   Aileen M. Moloney, Rebecca J. Griffin, Suzanne Timmons, R. O'Connor +2 more

   2010Neurobiology of Aging751 citations

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2. Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology

   Rebecca J. Griffin, Aileen M. Moloney, M. Kelliher, J. Johnston +4 more

   2005Journal of Neurochemistry472 citations

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3. The age‐related attenuation in long‐term potentiation is associated with microglial activation

   Rebecca J. Griffin, R. Nally, Y. Nolan, Y. McCartney +2 more

   2006Journal of Neurochemistry277 citations

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4. IL‐4 attenuates the neuroinflammation induced by amyloid‐β in vivo and in vitro

   A. Lyons, Rebecca J. Griffin, C. Costelloe, Rachael M. Clarke +1 more

   2007Journal of Neurochemistry133 citations Open access

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5. Decreased neuronal CD200 expression in IL-4-deficient mice results in increased neuroinflammation in response to lipopolysaccharide.

   A. Lyons, Keith McQuillan, Brian F. Deighan, Julie-Ann O’Reilly +8 more

   2009Brain, behavior, and immunity99 citations

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6. Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain.

   D. Loane, Brian F. Deighan, Rachael M. Clarke, Rebecca J. Griffin +2 more

   2009Neurobiology of Aging88 citations

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7. P4‐222: Defects in IGF‐1 receptor, insulin receptor and insulin receptor substrate proteins in Alzheimer's disease neurons indicate resistance to insulin and IGF‐1 signaling

   Cora O' Neill, Aileen M. Moloney, Rebecca J. Griffin, Meghan F. Coakley +3 more

   20081 citations

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8. AKT signal transduction is impaired in the Alzheimer's disease brain

   Rebecca J. Griffin, C. Fennelly, R. O'Connor, C. O'Neill +3 more

   20021 citations

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9. P1–421: Impaired IGF–1 receptor and insulin receptor signal transduction in Alzheimer's disease

   Aileen M. Moloney, Rebecca J. Griffin, Suzanne Timmons, R. Ravid +2 more

   20060 citations

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10. O3–02–07: Excessive activation of Akt signalling links to neuronal cell death in Alzheimer's disease

    Cora O' Neill, Aileen M. Moloney, Suzanne Timmons, M. Kelliher +5 more

    20060 citations Open access

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11. P1-250 Loss and altered subcellular distribution of the phosphatase PTEN links to the development of Alzheimer's disease neurofibrillary pathology

    Aileen M. Moloney, Rebecca J. Griffin, R. Ravid, C. O'Neill

    20040 citations

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12. P1-278 Dying to survive: enhanced activation of AKT in AD temporal cortex, results in hyperphosphorylation of many AKT substrates including tau

    Rebecca J. Griffin, Suzanne Timmons, R. Ravid, C. O'Neill

    20040 citations

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13. Impairments in IGF-1-PKB signal transduction in Alzheimer's disease brain

    Rebecca J. Griffin, J. Johnston, C. H. Williams, R. Ravid +2 more

    20010 citations

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