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A. Andiappan · SciRah

Researcher profile · Semantic Scholar

A. Andiappan

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A. Andiappan — researcher profile on SciRah

h-index: 29
Works: 89
Citations: 6,125

Most-cited papers

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
U. Võsa, A. Claringbould, H. Westra, M. Bonder +104 more
2021Nature Genetics2,043 citations Open access
Semantic Scholar
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
Angli Xue, Yang Wu, Zhihong Zhu, Futao Zhang +79 more
2018Nature Communications721 citations Open access
Semantic Scholar
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis
U. Võsa, A. Claringbould, H. Westra, M. Bonder +96 more
2018bioRxiv512 citations Open access
Semantic Scholar
Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood
Ting Qi, Yang Wu, Jian Zeng, Futao Zhang +82 more
2018Nature Communications408 citations Open access
Semantic Scholar
Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances
P. Timmers, N. Mounier, K. Läll, K. Fischer +80 more
2019eLife252 citations Open access
Semantic Scholar
Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19
G. Carissimo, Wei-Li Xu, Immanuel Kwok, M. Y. Abdad +20 more
2020Nature Communications157 citations Open access
Semantic Scholar
Allergic airway diseases in a tropical urban environment are driven by dominant mono-specific sensitization against house dust mites
A. Andiappan, K. Puan, B. Lee, A. Nardin +5 more
2014Allergy. European Journal of Allergy and Clinical Immunology156 citations Open access
Semantic Scholar
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour
M. Mills, Felix C. Tropf, D. Brazel, N. V. van Zuydam +202 more
2021Nature Human Behaviour130 citations Open access
Semantic Scholar
Identification of new susceptibility loci for IgA nephropathy in Han Chinese
Ming Li, J. Foo, Jin-Quan Wang, H. Low +37 more
2015Nature Communications127 citations Open access
Semantic Scholar
Cell Specific eQTL Analysis without Sorting Cells
H. Westra, D. Arends, T. Esko, M. Peters +55 more
2014bioRxiv121 citations Open access
Semantic Scholar
Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy
Hong Liu, A. Irwanto, Xi'an Fu, Gong-Qi Yu +28 more
2015Nature Genetics110 citations
Semantic Scholar
Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles
Akshamal M. Gamage, K. Tan, Wharton O. Y. Chan, Jing Liu +7 more
2020PLoS Pathogens107 citations Open access
Semantic Scholar
Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response
Z. Her, Terk-Shin Teng, Jeslin J. L. Tan, Teck-Hui Teo +16 more
2014EMBO Molecular Medicine106 citations Open access
Semantic Scholar
Genome-Wide Association Study for Atopy and Allergic Rhinitis in a Singapore Chinese Population
A. Andiappan, De-Yun Wang, Ramani Anantharaman, P. Parate +7 more
2011PLoS ONE102 citations Open access
Semantic Scholar
Whole-transcriptome sequencing reveals heightened inflammation and defective host defence responses in chronic rhinosinusitis with nasal polyps
Yang Peng, X. Zi, Teng-Fei Tian, Bernett Lee +9 more
2019European Respiratory Journal70 citations Open access
Semantic Scholar
Role of IL‐13Rα2 in modulating IL‐13‐induced MUC5AC and ciliary changes in healthy and CRSwNP mucosa
Jing Liu, Ying-Ying Li, A. Andiappan, Y. Yan +9 more
2018Allergy. European Journal of Allergy and Clinical Immunology58 citations
Semantic Scholar
Atopic dermatitis microbiomes stratify into ecological dermotypes enabling microbial virulence and disease severity.
A. Tay, Chenhao Li, T. Nandi, K. R. Chng +15 more
2020Journal of Allergy and Clinical Immunology46 citations Open access
Semantic Scholar
Functional variants of 17q12-21 are associated with allergic asthma but not allergic rhinitis.
A. Andiappan, Y. Sio, Bernett Lee, B. K. Suri +10 more
2016Journal of Allergy and Clinical Immunology44 citations Open access
Semantic Scholar
Toll-like receptor gene polymorphisms are associated with allergic rhinitis: a case control study
D. Nilsson, A. Andiappan, C. Halldén, Wang-De Yun +3 more
2012BMC Medical Genetics43 citations Open access
Semantic Scholar
Systematic characterization of basophil anergy
K. Puan, A. Andiappan, Bernett Lee, Dilip Kumar +13 more
2017Allergy. European Journal of Allergy and Clinical Immunology39 citations
Semantic Scholar
Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease
M. Obeidat, Yunlong Nie, Virginia Chen, C. Shannon +12 more
2017Respiratory Research39 citations Open access
Semantic Scholar
Genome-Wide Analysis of Protein-Coding Variants in Leprosy.
Hong Liu, Zhen-Zhen Wang, Yi Li, Gong-Qi Yu +46 more
2017Journal of Investigative Dermatology38 citations Open access
Semantic Scholar
Genetic analysis of an allergic rhinitis cohort reveals an intercellular epistasis between FAM134B and CD39
R. Melchiotti, K. Puan, A. Andiappan, T. Poh +9 more
2014BMC Medical Genetics35 citations Open access
Semantic Scholar
Genome-wide analysis of the genetic regulation of gene expression in human neutrophils
A. Andiappan, R. Melchiotti, T. Poh, Michelle Nah +23 more
2015Nature Communications33 citations Open access
Semantic Scholar
A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus
Dilip Kumar, K. Puan, A. Andiappan, Bernett Lee +30 more
2017Genome Medicine32 citations Open access
Semantic Scholar
Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium.
N. Farzan, S. Vijverberg, A. Andiappan, Lambang Arianto +42 more
2017Pharmacogenomics (London)31 citations Open access
Semantic Scholar
Evaluating the transferability of Hapmap SNPs to a Singapore Chinese population
A. Andiappan, Ramani Anantharaman, Pallavi Parate Nilkanth, De-Yun Wang +1 more
2010BMC Genetics31 citations Open access
Semantic Scholar
XXIV World Allergy Congress 2015
Heung-Man Lee, Ii-Ho Park, Jae-Min Shin, H. Yoon +496 more
2016The World Allergy Organization Journal30 citations Open access
Semantic Scholar
A functional brain-derived neurotrophic factor (BDNF) gene variant increases the risk of moderate-to-severe allergic rhinitis.
P. Jin, A. Andiappan, Jia Min Quek, Bernett Lee +22 more
2015Journal of Allergy and Clinical Immunology30 citations
Semantic Scholar
Genetic variation in BDNF is associated with allergic asthma and allergic rhinitis in an ethnic Chinese population in Singapore.
A. Andiappan, P. Parate, Ramani Anantharaman, B. K. Suri +2 more
2011Cytokine29 citations
Semantic Scholar
Genome-wide association study identifies PERLD1 as asthma candidate gene
Ramani Anantharaman, A. Andiappan, Pallavi Parate Nilkanth, B. K. Suri +2 more
2011BMC Medical Genetics28 citations Open access
Semantic Scholar
Poor Reproducibility of Allergic Rhinitis SNP Associations
D. Nilsson, A. Andiappan, C. Halldén, C. F. Tim +3 more
2013PLoS ONE26 citations Open access
Semantic Scholar
RNA Sequencing of H3N2 Influenza Virus-Infected Human Nasal Epithelial Cells from Multiple Subjects Reveals Molecular Pathways Associated with Tissue Injury and Complications
K. Tan, A. Andiappan, Bernett Lee, Yan Yan +11 more
2019Cells23 citations Open access
Semantic Scholar
Investigating highly replicated asthma genes as candidate genes for allergic rhinitis
A. Andiappan, D. Nilsson, C. Halldén, Wang-De Yun +3 more
2013BMC Medical Genetics22 citations Open access
Semantic Scholar
Maternal stress triggers early-life eczema through fetal mast cell programming
N. Serhan, Nasser S. Abdullah, Nadine Gheziel, Alexia Loste +24 more
2025Nature21 citations Open access
Semantic Scholar
Predicting antipsychotic responsiveness using a machine learning classifier trained on plasma levels of inflammatory markers in schizophrenia
Yin-Yee Jie, Ser-Xian Phua, Mei-See Yuen, A. Andiappan +2 more
2025Translational Psychiatry21 citations Open access
Semantic Scholar
A comprehensive association analysis confirms ZMIZ1 to be a susceptibility gene for vitiligo in Chinese population
Yong-Hu Sun, X. Zuo, Xiao-Dong Zheng, Fu-Sheng Zhou +15 more
2014Journal of Medical Genetics21 citations
Semantic Scholar
Role of IL-13Ra2 in modulating IL-13 induced MUC5AC and ciliary changes in healthy and CRSwNP mucosa
Jing Liu, Ying-Ying Li, A. Andiappan, Yan Yan +9 more
2019Airway cell biology and immunopathology20 citations
Semantic Scholar
Neuropeptide Y associated with asthma in young adults.
Yan-Xia Lu, A. Andiappan, Bernett Lee, R. Ho +10 more
2016Neuropeptides20 citations
Semantic Scholar
Refining Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder Genetic Loci by Integrating Summary Data From Genome-wide Association, Gene Expression, and DNA Methylation Studies.
Anke R. Hammerschlag, E. Byrne, M. Bartels, N. Wray +118 more
2020Biological Psychiatry19 citations Open access
Semantic Scholar
Virus infection drives IL-2 antibody complexes into pro-inflammatory agonists in mice
Wendy W. L. Lee, Teck-Hui Teo, F. Lum, A. Andiappan +4 more
2016Scientific Reports19 citations Open access
Semantic Scholar
Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early prognostic marker for severe COVID-19
G. Carissimo, Wei-Li Xu, Immanuel Kwok, M. Y. Abdad +20 more
2020bioRxiv18 citations Open access
Semantic Scholar
Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn’s disease and leprosy
Yong-Hu Sun, A. Irwanto, Licht Toyo-oka, Myunghee Hong +24 more
2016Scientific Reports18 citations Open access
Semantic Scholar
Resistin expression in human monocytes is controlled by two linked promoter SNPs mediating NFKB p50/p50 binding and C-methylation
Dilip Kumar, Bernett Lee, K. Puan, Wendy W. L. Lee +12 more
2019Scientific Reports17 citations Open access
Semantic Scholar
Transcriptomics of rhinovirus persistence reveals sustained expression of RIG‐I and interferon‐stimulated genes in nasal epithelial cells in vitro
Hui-Ong Hsiao, A. Andiappan, Kaibo Duan, Josephine Lum +8 more
2022Allergy. European Journal of Allergy and Clinical Immunology15 citations
Semantic Scholar
Variation in Uteroglobin-Related Protein 1 (UGRP1) gene is associated with Allergic Rhinitis in Singapore Chinese
A. Andiappan, Wei Sheng Yeo, P. Parate, Ramani Anantharaman +3 more
2011BMC Medical Genetics15 citations Open access
Semantic Scholar
Genome-wide association studies of exacerbations in children using long-acting beta2-agonists
E. Slob, L. B. Richards, S. Vijverberg, C. Longo +18 more
2021Pediatric Allergy and Immunology14 citations Open access
Semantic Scholar
Data-Driven Analysis of COVID-19 Reveals Persistent Immune Abnormalities in Convalescent Severe Individuals
Jackwee Lim, K. Puan, L. Wang, K. Teng +29 more
2021Frontiers in Immunology13 citations Open access
Semantic Scholar
Replication of genome-wide association study loci for allergic rhinitis and house dust mite sensitization in an Asian population of ethnic Chinese in Singapore.
A. Andiappan, De-Yun Wang, Ramani Anantharaman, B. K. Suri +4 more
2013Journal of Allergy and Clinical Immunology13 citations
Semantic Scholar
Evaluation of the applicability of the Immuno-solid-phase allergen chip (ISAC) assay in atopic patients in Singapore
A. Santosa, A. Andiappan, O. Rotzschke, Hung-Chew Wong +4 more
2015Clinical and Translational Allergy12 citations Open access
Semantic Scholar

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