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R. Ihara · SciRah

Researcher profile · Semantic Scholar

R. Ihara

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R. Ihara — researcher profile on SciRah

h-index: 18
Works: 91
Citations: 931

Most-cited papers

Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study
E. Morenas-Rodriguez, Yan Li, B. Nuscher, N. Franzmeier +141 more
2022Lancet Neurology138 citations Open access
Semantic Scholar
Japanese and North American Alzheimer's Disease Neuroimaging Initiative studies: Harmonization for international trials
T. Iwatsubo, A. Iwata, Kazushi Suzuki, R. Ihara +13 more
2018Alzheimer's & Dementia133 citations Open access
Semantic Scholar
RNA binding mediates neurotoxicity in the transgenic Drosophila model of TDP-43 proteinopathy.
R. Ihara, Koji Matsukawa, Y. Nagata, Hayato Kunugi +7 more
2013Human Molecular Genetics76 citations Open access
Semantic Scholar
Combining plasma Aβ and p-tau217 improves detection of brain amyloid in non-demented elderly
Y. Niimi, S. Janelidze, Kenichiro Sato, N. Tomita +19 more
2024Alzheimer's Research & Therapy66 citations Open access
Semantic Scholar
Effect of apolipoprotein E ε4 allele on the progression of cognitive decline in the early stage of Alzheimer's disease
Kazushi Suzuki, A. Hirakawa, R. Ihara, A. Iwata +5 more
2020Alzheimer's & Dementia30 citations Open access
Semantic Scholar
CSF P-Tau181 and Other Biomarkers in Patients With Neuronal Intranuclear Inclusion Disease
M. Kurihara, H. Komatsu, R. Sengoku, M. Shibukawa +20 more
2022Neurology28 citations Open access
Semantic Scholar
Effects of sex, educational background, and chronic kidney disease grading on longitudinal cognitive and functional decline in patients in the Japanese Alzheimer's Disease Neuroimaging Initiative study
A. Iwata, T. Iwatsubo, R. Ihara, Kazushi Suzuki +9 more
2018Alzheimer's & Dementia28 citations Open access
Semantic Scholar
Relative Neuron Loss in Hippocampal Sclerosis of Aging and Alzheimer Disease
R. Ihara, Benjamin D. Vincent, Michael R. Baxter, Erin E. Franklin +4 more
2018Annals of Neurology27 citations Open access
Semantic Scholar
Self-assembly of FUS through its low-complexity domain contributes to neurodegeneration
Taisei Matsumoto, Koji Matsukawa, Naruaki Watanabe, Y. Kishino +5 more
2018Human Molecular Genetics23 citations Open access
Semantic Scholar
Different AT(N) profiles and clinical progression classified by two different N markers using total tau and neurofilament light chain in cerebrospinal fluid
K. Kasuga, M. Kikuchi, T. Tsukie, Kazushi Suzuki +7 more
2022BMJ Neurology Open22 citations Open access
Semantic Scholar
Predicting amyloid risk by machine learning algorithms based on the A4 screen data: Application to the Japanese Trial‐Ready Cohort study
Kenichiro Sato, R. Ihara, Kazushi Suzuki, Yoshiki Niimi +9 more
2021Alzheimer's & Dementia22 citations Open access
Semantic Scholar
Clinical and cognitive characteristics of preclinical Alzheimer's disease in the Japanese Alzheimer's Disease Neuroimaging Initiative cohort
R. Ihara, A. Iwata, Kazushi Suzuki, T. Ikeuchi +2 more
2018Alzheimer's & Dementia22 citations Open access
Semantic Scholar
Real‐world lecanemab adoption in Japan 1 year after launch: Insights from 311 specialists on infrastructure and reimbursement barriers
Kenichiro Sato, Yoshiki Niimi, R. Ihara, A. Iwata +9 more
2025Alzheimer's & Dementia19 citations
Semantic Scholar
Identification of prognostic factors to predict cognitive decline of patients with early Alzheimer's disease in the Japanese Alzheimer's Disease Neuroimaging Initiative study
T. Yagi, M. Kanekiyo, Junichi Ito, R. Ihara +4 more
2019Alzheimer's & Dementia19 citations Open access
Semantic Scholar
Familial Amyotrophic Lateral Sclerosis-linked Mutations in Profilin 1 Exacerbate TDP-43-induced Degeneration in the Retina of Drosophila melanogaster through an Increase in the Cytoplasmic Localization of TDP-43*
Koji Matsukawa, T. Hashimoto, Taisei Matsumoto, R. Ihara +4 more
2016Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Therapeutic time window of disease‐modifying therapy for early Alzheimer's disease
Saki Nakashima, Kenichiro Sato, Yoshiki Niimi, R. Ihara +4 more
2025Alzheimer's & Dementia18 citations Open access
Semantic Scholar
Public perceptions related to healthcare preparedness to anti-amyloid therapies for Alzheimer’s Disease in Japan
Kenichiro Sato, Yoshiki Niimi, R. Ihara, A. Iwata +8 more
2024Alzheimer's Research & Therapy18 citations Open access
Semantic Scholar
Lower Serum Calcium as a Potentially Associated Factor for Conversion of Mild Cognitive Impairment to Early Alzheimer’s Disease in the Japanese Alzheimer’s Disease Neuroimaging Initiative
Kenichiro Sato, T. Mano, R. Ihara, Kazushi Suzuki +11 more
2019Journal of Alzheimer's Disease18 citations
Semantic Scholar
Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer’s disease
Phoebe Valdes, Andrew B. Caldwell, Qing Liu, Michael Q. Fitzgerald +140 more
2025Alzheimer's Research & Therapy16 citations Open access
Semantic Scholar
Usability of a Web-Based Registry for Preclinical Alzheimer’s Disease: Implications from a Cross-Sectional Online Survey
Kenichiro Sato, Y. Niimi, R. Ihara, K. Suzuki +2 more
2024The journal of prevention of Alzheimer's disease12 citations Open access
Semantic Scholar
α-synuclein seed amplification assay sensitivity may be associated with cardiac MIBG abnormality among patients with Lewy body disease
M. Kurihara, K. Satoh, R. Shimasaki, K. Hatano +7 more
2024npj Parkinson's Disease12 citations Open access
Semantic Scholar
Visualizing modules of coordinated structural brain atrophy during the course of conversion to Alzheimer's disease by applying methodology from gene co-expression analysis
Kenichiro Sato, T. Mano, H. Matsuda, M. Senda +10 more
2019NeuroImage: Clinical12 citations Open access
Semantic Scholar
Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls
H. Masuda, M. Mori, Shigeki Hirano, A. Uzawa +496 more
2023Scientific Reports11 citations Open access
Semantic Scholar
A first‐in‐human study of the anti‐inflammatory profibrinolytic TMS‐007, an SMTP family triprenyl phenol
T. Moritoyo, Naoko Nishimura, Keiko Hasegawa, S. Ishii +12 more
2022British Journal of Clinical Pharmacology11 citations Open access
Semantic Scholar
Impact of Istradefylline on Levodopa Dose Escalation in Parkinson’s Disease: ISTRA ADJUST PD Study, a Multicenter, Open-Label, Randomized, Parallel-Group Controlled Study
T. Hatano, R. Sengoku, Hiroshi Nagayama, Naotake Yanagisawa +25 more
2024Neurological Therapeutics10 citations Open access
Semantic Scholar
Correlations between cerebrospinal fluid homovanillic acid and dopamine transporter SPECT in degenerative parkinsonian syndromes
Ryoji Goto, M. Kurihara, M. Kameyama, H. Komatsu +10 more
2023Journal of neural transmission10 citations Open access
Semantic Scholar
High sensitivity of asymmetric 18F-THK5351 PET abnormality in patients with corticobasal syndrome
M. Kurihara, K. Ishibashi, T. Matsubara, K. Hatano +9 more
2023Scientific Reports10 citations Open access
Semantic Scholar
Modernizing diagnosis of Alzheimer's disease: A review of global trends and Asia‐specific perspectives
T. Iwatsubo, Reisa A. Sperling, A. Algeciras-Schimnich, H. Arai +40 more
2025Alzheimer's & Dementia9 citations Open access
Semantic Scholar
Efficacy and Cost-effectiveness of Promotion Methods to Recruit Participants to an Online Screening Registry for Alzheimer Disease Prevention Trials: Observational Study
Kenichiro Sato, Yoshiki Niimi, R. Ihara, Kazushi Suzuki +3 more
2020Journal of Medical Internet Research9 citations Open access
Semantic Scholar
Associations of cerebrospinal fluid monoamine metabolites with striatal dopamine transporter binding and 123I-meta-iodobenzylguanidine cardiac scintigraphy in Parkinson's disease: Multivariate analyses.
R. Shimasaki, M. Kurihara, K. Hatano, Ryoji Goto +6 more
2024Parkinsonism & Related Disorders7 citations Open access
Semantic Scholar
A Japanese Multicenter Study on PET and Other Biomarkers for Subjects with Potential Preclinical and Prodromal Alzheimer's Disease
M. Senda, K. Ishii, K Ito, T. Ikeuchi +22 more
2021The journal of prevention of Alzheimer's disease7 citations Open access
Semantic Scholar
Blood‐based biomarker prescreening with different testing combinations and cutoffs: A simulation study examining efficacy and cost‐effectiveness in Alzheimer's disease prevention studies
Kenichiro Sato, Yoshiki Niimi, R. Ihara, A. Iwata +2 more
2025Alzheimer's & Dementia6 citations Open access
Semantic Scholar
APOE-ε4 allele[s]-associated adverse events reported from placebo arm in clinical trials for Alzheimer's disease: implications for anti-amyloid beta therapy
Kenichiro Sato, Yoshiki Niimi, R. Ihara, Kazushi Suzuki +2 more
2024Frontiers in dementia6 citations Open access
Semantic Scholar
Clinical Application of 18F-THK5351 PET to Image Ongoing Astrogliosis in MSA-P and MSA-C.
Soichiro Kondo, K. Ishibashi, Kenji Ishii, A. Iwata +1 more
2024Clinical Nuclear Medicine5 citations
Semantic Scholar
Advertisement by medical facilities as an opportunity route of APOE genetic testing in Japan: a website analysis
Kenichiro Sato, Yoshiki Niimi, R. Ihara, A. Iwata +2 more
2024Journal of Community Genetics5 citations Open access
Semantic Scholar
Detailed Assessment of 18F-THK5351 Distribution Pattern in the Midbrain: Comparison With Progressive Supranuclear Palsy and Corticobasal Syndrome
K. Ishibashi, M. Kurihara, R. Ihara, M. Higashihara +2 more
2023Clinical Nuclear Medicine5 citations Open access
Semantic Scholar
Patients’ choices and eligibility for anti‐amyloid therapy in Japan's universal insurance
R. Ihara, M. Kurihara, K. Hatano, T. Bannai +7 more
2026Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring4 citations Open access
Semantic Scholar
ATNIVS biomarker heterogeneity in real-world patients receiving lecanemab
M. Kurihara, R. Ihara, G. Yoshii, R. Shimasaki +9 more
2026The journal of prevention of Alzheimer's disease4 citations Open access
Semantic Scholar
Cognitive function instrument-based anosognosia to predict amyloid status
Yuichiro Furuya, Kenichiro Sato, Yoshiki Niimi, R. Ihara +3 more
2025Journal of Alzheimer's Disease4 citations
Semantic Scholar
Cohort-Specific Optimization of Models Predicting Preclinical Alzheimer's Disease, to Enhance Screening Performance in the Middle of Preclinical Alzheimer's Disease Clinical Studies
K. Sato, T. Mano, R. Ihara, K. Suzuki +4 more
2021The journal of prevention of Alzheimer's disease4 citations Open access
Semantic Scholar
Gait improvement after levofloxacin administration in a progressive supranuclear palsy patient
M. Kurihara, Kenta Orimo, T. Mano, Ryoji Miyano +5 more
2020Clinical Parkinsonism & Related Disorders4 citations Open access
Semantic Scholar
Amyloid-related imaging abnormalities in Japanese patients with Alzheimer’s disease treated with Lecanemab: A real-world study
R. Shimasaki, M. Kurihara, T. Bannai, K. Hatano +5 more
2026The journal of prevention of Alzheimer's disease3 citations Open access
Semantic Scholar
Simplifying Alzheimer’s Disease Monitoring: A Novel Machine-Learning Approach to Estimate the Clinical Dementia Rating Sum of Box Changes Using the Mini-Mental State Examination and Functional Activities Questionnaire
Kenichiro Sato, Yoshiki Niimi, R. Ihara, Kazushi Suzuki +2 more
2024Journal of Alzheimer's Disease3 citations
Semantic Scholar
[New diagnostic guidelines for Alzheimer's disease by NIA/AA].
R. Ihara
2016Nihon rinsho. Japanese journal of clinical medicine3 citations
Semantic Scholar
Impact of istradefylline on motor and non-motor symptoms in patients with Parkinson’s disease: Subanalysis of the ISTRA ADJUST PD
Hiroshi Nagayama, Osamu Kano, R. Sengoku, Naotake Yanagisawa +25 more
2025Clinical Parkinsonism & Related Disorders2 citations
Semantic Scholar
Regional Variability in MRI Scans with Different Magnetic Field Strengths in Japan: Implications for Healthcare Preparedness for Alzheimer’s Disease Treatment
Kenichiro Sato, Yoshiki Niimi, R. Ihara, Atsushi Iwata +1 more
2024Biomedicines2 citations Open access
Semantic Scholar
Adverse Events as a Cause of Unblinding of Allocated Arms in Anti-Amyloid Therapy Trials: A Meta-Analysis of the Predictive Value
Kenichiro Sato, Yoshiki Niimi, R. Ihara, A. Iwata +1 more
2024Journal of Alzheimer's Disease2 citations
Semantic Scholar
Safety and pharmacokinetics of single and repeated dose of a novel formulation of intra-nasal Oxytocin (TTA-121) in healthy Japanese volunteers (double blind, placebo-controlled Phase 1 trial)
C. Sakanaka, R. Ihara, A. Kishi, K. Kirihara +8 more
20182 citations Open access
Semantic Scholar
Cost analyses of plasma p-tau217 versus p-tau217/Aβ42 ratio using two-step approach in the Japanese health care system
M. Kurihara, R. Ihara, Kenichiro Sato, Atsushi Iwata
2026The journal of prevention of Alzheimer's disease1 citations Open access
Semantic Scholar
How many sites are enough? a novel, site-based power analysis method for real-world registry studies of anti-amyloid monoclonal antibodies
Kenichiro Sato, Yoshiki Niimi, R. Ihara, A. Iwata +1 more
2025JAR life1 citations Open access
Semantic Scholar

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Kenichiro Sato×19
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Kenichiro Sato — researcher profile on SciRah
A. Iwata×15
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A. Iwata — researcher profile on SciRah
T. Iwatsubo×14
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T. Iwatsubo — researcher profile on SciRah
A. Iwata×13
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A. Iwata — researcher profile on SciRah

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Kazushi Suzuki×12

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Kazushi Suzuki — researcher profile on SciRah

Yoshiki Niimi×12

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Yoshiki Niimi — researcher profile on SciRah

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T. Ikeuchi — researcher profile on SciRah

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K. Kasuga — researcher profile on SciRah

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M. Kurihara — researcher profile on SciRah

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R. Kuwano — researcher profile on SciRah

Kazushi Suzuki×6

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Kazushi Suzuki — researcher profile on SciRah