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D. Hyndman · SciRah

Researcher profile · Semantic Scholar

D. Hyndman

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D. Hyndman — researcher profile on SciRah

h-index: 15
Works: 28
Citations: 1,333

Most-cited papers

The aldo-keto reductase superfamily homepage.
D. Hyndman, David R. Bauman, Vladi V. Heredia, T. Penning
2003Chemico-Biological Interactions310 citations
Semantic Scholar
Human aldose reductase and human small intestine aldose reductase are efficient retinal reductases: consequences for retinoid metabolism.
Bernat Crosas, D. Hyndman, O. Gallego, Sı́lvia Martras +3 more
2003Biochemical Journal163 citations Open access
Semantic Scholar
Urate Handling in the Human Body
D. Hyndman, Sha Liu, J. Miner
2016Current Rheumatology Reports155 citations Open access
Semantic Scholar
Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney
J. Miner, P. Tan, D. Hyndman, Sha Liu +9 more
2016Arthritis Research & Therapy96 citations Open access
Semantic Scholar
Sequence and expression levels in human tissues of a new member of the aldo-keto reductase family.
D. Hyndman, T.Geoff Flynn
1998Biochimica et Biophysica Acta94 citations
Semantic Scholar
Studies on pig muscle aldose reductase. Kinetic mechanism and evidence for a slow conformational change upon coenzyme binding.
T. Kubiseski, D. Hyndman, N. A. Morjana, T. Flynn
1992Journal of Biological Chemistry88 citations Open access
Semantic Scholar
Nucleotide-binding sites on Escherichia coli F1-ATPase. Specificity of noncatalytic sites and inhibition at catalytic sites by MgADP.
D. Hyndman, Y. M. Milgrom, E. A. Bramhall, R. L. Cross
1994Journal of Biological Chemistry84 citations Open access
Semantic Scholar
Decreased expression of cyclic adenosine monophosphate-regulated aldose reductase (AKR1B1) is associated with malignancy in human sporadic adrenocortical tumors.
A. Lefrançois-Martinez, J. Bertherat, P. Val, C. Tournaire +6 more
2004Journal of Clinical Endocrinology and Metabolism73 citations Open access
Semantic Scholar
RAB2A: A Major Subacrosomal Protein of Bovine Spermatozoa Implicated in Acrosomal Biogenesis1
Jeremi R. Mountjoy, Wei Xu, Dave McLeod, D. Hyndman +1 more
2008Biology of Reproduction60 citations Open access
Semantic Scholar
Erratum to: Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney
J. Miner, P. Tan, D. Hyndman, Sha Liu +9 more
2016Arthritis Research & Therapy46 citations Open access
Semantic Scholar
Cloning, Sequencing, and Enzymatic Activity of an Inducible Aldo-Keto Reductase from Chinese Hamster Ovary Cells*
D. Hyndman, R. Takenoshita, Nathalie Vera, Stephen C. Pang +1 more
1997Journal of Biological Chemistry30 citations Open access
Semantic Scholar
Protein immobilization to alumina supports: II. Papain immobilization to alumina via organophosphate linkers
D. Hyndman, R. Burrell, G. Lever, T. Flynn
1992Biotechnology and Bioengineering29 citations
Semantic Scholar
Protein immobilization to alumina supports: I. Characterization of alumina‐organophosphate ligand interactions and use in the attachment of papain
D. Hyndman, T. Flynn, G. Lever, R. Burrell
1992Biotechnology and Bioengineering20 citations
Semantic Scholar
The crystal structure of an aldehyde reductase Y50F mutant-NADP complex and its implications for substrate binding.
Q. Ye, D. Hyndman, N. Green, L. Li +2 more
2001Chemico-Biological Interactions18 citations
Semantic Scholar
Crystal structure of CHO reductase, a member of the aldo‐keto reductase superfamily
Q. Ye, D. Hyndman, Xuhong Li, T. Flynn +1 more
2000Proteins: Structure, Function, and Bioinformatics17 citations Open access
Semantic Scholar
The aldo-keto reductases and their role in cancer.
D. Hyndman, T. Flynn
1999Advances in Experimental Medicine and Biology14 citations
Semantic Scholar
SAT0521 Lesinurad, an Inhibitor of the Uric Acid Transporter URAT1 and A Potential Therapy for Gout, Requires URAT1 Phenylalanine 365 for High Affinity Inhibition
P. Tan, D. Hyndman, J. Miner
20149 citations
Semantic Scholar
γ -Hydroxybutyrate and oxidative stress
M. Mamelak, D. Hyndman
20027 citations
Semantic Scholar
Crystal structure of an aldehyde reductase Y50F mutant‐NADP complex and its implications for substrate binding
Q. Ye, D. Hyndman, N. Green, Xuhong Li +3 more
2001Proteins: Structure, Function, and Bioinformatics7 citations
Semantic Scholar
CT diagnosis and laparoscopic treatment of hepatic abscess secondary to fish bone transmigration through the stomach wall
D. Hyndman, R. Chaudhary, Shawna M. Kettyle, H. Husein
2023Radiology Case Reports5 citations Open access
Semantic Scholar
Chemical modification of aldehyde and aldose reductase by pyridoxal 5'-phosphate.
T. Flynn, B. Charington, C. Lyons, H. Chao +2 more
1989Progress in clinical and biological research5 citations
Semantic Scholar
Cloning, sequencing, and enzymatic activity of an inducible aldo-keto reductase from Chinese hamster ovary cells.
T. Flynn, D. Hyndman, Reiko Takenoshita, Nathalie Vera +1 more
1997Journal of Biological Chemistry3 citations
Semantic Scholar
Enhancement of aldose reductase activity by modification of an active site lysine: a possible mechanism for in vivo activation.
T. Flynn, Christina Lyons, D. Hyndman
1990Advances in Enzyme Regulation2 citations
Semantic Scholar
THU0491 A Novel Method of Estimating Extra-Renal Clearance of Uric Acid
D. Hyndman, S. Liu, J. Hall, J. Miner
20160 citations
Semantic Scholar
THU0492 Uric Acid Transport Kinetics in The Kidney: Detection of Renal Secretion and The Mechanism of Low FEUA
Sha Liu, D. Hyndman, J. Miner
20160 citations
Semantic Scholar
SAT0543 A Novel Equation to Effectively Estimate 24-Hour Urinary Uric Acid Excretion
Sha Liu, D. Hyndman, M. Cravets, J. Miner
20140 citations
Semantic Scholar
CHO REDUCTASE WITH NADP
Q. Ye, X. Li, D. Hyndman, T. Flynn +1 more
20000 citations
Semantic Scholar
Inhibition of aldo-keto reductases (AKRs)
T. G. Flynn, D. Hyndman
19980 citations
Semantic Scholar

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