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B. Ledermann · SciRah

Researcher profile · Semantic Scholar

B. Ledermann

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B. Ledermann — researcher profile on SciRah

h-index: 36
Works: 52
Citations: 12K

Most-cited papers

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
D. Kägi, B. Ledermann, K. Bürki, P. Seiler +5 more
1994Nature1,975 citations
Semantic Scholar
Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity.
D. Kägi, F. Vignaux, B. Ledermann, K. Bürki +4 more
1994Science1,726 citations
Semantic Scholar
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology.
C. Sturchler-Pierrat,, D. Abramowski, M. Duke, K. Wiederhold +12 more
1997Proceedings of the National Academy of Sciences of the United States of America1,567 citations Open access
Semantic Scholar
Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo.
D. Kägi, B. Ledermann, K. Bürki, R. Zinkernagel +1 more
1996Annual Review of Immunology673 citations
Semantic Scholar
General anesthetic actions in vivo strongly attenuated by a point mutation in the GABAA receptor β3 subunit
Rachel Jurd, Margarete Arrasa, S. Lambert, B. Drexler +7 more
2003The FASEB Journal602 citations
Semantic Scholar
The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas.
Andrea Krapp, M. Knöfler, B. Ledermann, K. Bürki +4 more
1998Genes & Development563 citations Open access
Semantic Scholar
Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury.
M. Simonen, V. Pedersen, O. Weinmann, L. Schnell +6 more
2003Neuron444 citations Open access
Semantic Scholar
Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6.
S. Volarević, M. J. Stewart, B. Ledermann, F. Zilberman +5 more
2000Science393 citations
Semantic Scholar
Distinct roles for lymphotoxin‐α and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue
H. Körner, M. Cook, D. Riminton, F. Lemckert +5 more
1997357 citations
Semantic Scholar
Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart
P. Ruiz, V. Brinkmann, B. Ledermann, Martin Behrend +7 more
1996Journal of Cell Biology356 citations Open access
Semantic Scholar
The roles of perforin‐ and Fas‐dependent cytotoxicity in protection against cytopathic and noncytopathic viruses
D. Kägi, P. Seiler, J. Pavlovic, B. Ledermann +3 more
1995European Journal of Immunology322 citations
Semantic Scholar
Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling.
M. Mohrs, B. Ledermann, G. Köhler, Andreas Dorfmüller +2 more
1999Journal of Immunology312 citations
Semantic Scholar
Resistance of Fc receptor- deficient mice to fatal glomerulonephritis.
Seung Yong Park, S. Ueda, H. Ohno, Y. Hamano +12 more
1998Journal of Clinical Investigation308 citations Open access
Semantic Scholar
CD8+ T cell‐mediated protection against an intracellular bacterium by perforin‐dependent cytotoxicity
D. Kägi, B. Ledermann, K. Bürki, H. Hengartner +1 more
1994European Journal of Immunology245 citations
Semantic Scholar
Establishment of a germ-line competent C57BL/6 embryonic stem cell line.
B. Ledermann, K. Bürki
1991Experimental Cell Research198 citations
Semantic Scholar
Absence of the prion protein homologue Doppel causes male sterility
A. Behrens, N. Genoud, H. Naumann, T. Rülicke +4 more
2002EMBO Journal174 citations Open access
Semantic Scholar
IgD can largely substitute for loss of IgM function in B cells
C. Lutz, B. Ledermann, M. Kosco-Vilbois, A. Ochsenbein +3 more
1998Nature160 citations
Semantic Scholar
Porphobilinogen deaminase deficiency in mice causes a neuropathy resembling that of human hepatic porphyria
R. Lindberg, C. Porcher, B. Grandchamp, B. Ledermann +4 more
1996Nature Genetics151 citations
Semantic Scholar
Wnt signalling inhibits neural differentiation of embryonic stem cells by controlling bone morphogenetic protein expression.
Lorenz Haegele, B. Ingold, H. Naumann, G. Tabatabai +2 more
2003Molecular and cellular neurosciences129 citations Open access
Semantic Scholar
Lymphocyte‐mediated Cytotoxicity in vitro and in vivo: Mechanisms and Significance
D. Kägi, B. Ledermann, K. Bürki, R. Zinkernagel +1 more
1995Immunological Reviews118 citations
Semantic Scholar
Mice lacking phosphatase PP2A subunit PR61/B’δ (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3β
J. Louis, E. Martens, P. Borghgraef, Caroline Lambrecht +11 more
2011Proceedings of the National Academy of Sciences of the United States of America116 citations Open access
Semantic Scholar
Acute rejection of vascular heart allografts by perforin‐deficient mice
M. Schulz, H. Schuurman, J. Joergensen, C. Steiner +7 more
1995European Journal of Immunology103 citations
Semantic Scholar
Specific proteolytic cleavage of agrin regulates maturation of the neuromuscular junction
M. Bolliger, A. Zurlinden, Daniel Lüscher, L. Bütikofer +13 more
2010Journal of Cell Science102 citations Open access
Semantic Scholar
Efficient targeting of the IL-4 gene in a BALB/c embryonic stem cell line
N. Noben-Trauth, Georges Köhler, K. Bürki, B. Ledermann
1996Transgenic research99 citations
Semantic Scholar
Specific cleavage of agrin by neurotrypsin, a synaptic protease linked to mental retardation
R. Reif, Susanne Sales, S. Hettwer, B. Dreier +10 more
2007The FASEB Journal98 citations
Semantic Scholar
Fliih, a Gelsolin-Related Cytoskeletal Regulator Essential for Early Mammalian Embryonic Development
H. Campbell, Shelley Fountain, I. McLennan, L. Berven +9 more
2002Molecular and Cellular Biology91 citations Open access
Semantic Scholar
Alternative NF‐κB signaling regulates mTEC differentiation from podoplanin‐expressing precursors in the cortico‐medullary junction
L. Onder, V. Nindl, E. Scandella, Qian Chai +10 more
2015European Journal of Immunology89 citations Open access
Semantic Scholar
Embryonic Stem Cells and Gene Targeting
B. Ledermann
2000Experimental Physiology81 citations Open access
Semantic Scholar
Strong and ubiquitous expression of transgenes targeted into the β‐actin locus by Cre/lox cassette replacement
D. Shmerling, Claus-Peter Danzer, Xiaohong Mao, J. Boisclair +9 more
2005Genesis77 citations Open access
Semantic Scholar
Antiviral immune responses in gene-targeted mice expressing the immunoglobulin heavy chain of virus-neutralizing antibodies
Lars Hangartner, B. Senn, B. Ledermann, U. Kalinke +8 more
2003Proceedings of the National Academy of Sciences of the United States of America72 citations Open access
Semantic Scholar
Permissive role of thrombopoietin and granulocyte colony-stimulating factor receptors in hematopoietic cell fate decisions in vivo.
R. Stoffel, Sandra Ziegler, Nico Ghilardi, B. Ledermann +2 more
1999Proceedings of the National Academy of Sciences of the United States of America72 citations Open access
Semantic Scholar
The Transcription Factor Early Growth Response 1 (Egr-1) Advances Differentiation of Pre-B and Immature B Cells
Adelheid Dinkel, K. Warnatz, B. Ledermann, A. Rolink +3 more
1998Journal of Experimental Medicine68 citations Open access
Semantic Scholar
Dwarfism and Low Insulin-like Growth Factor-1 Due to Dopamine Depletion in Pts–/– Mice Rescued by Feeding Neurotransmitter Precursors and H4-biopterin*
L. Elzaouk, W. Leimbacher, M. Turri, B. Ledermann +3 more
2003Journal of Biological Chemistry65 citations Open access
Semantic Scholar
Islet-Brain1/JNK-interacting Protein-1 Is Required for Early Embryogenesis in Mice*
Nancy A. Thompson, J. Haefliger, A. Senn, T. Tawadros +4 more
2001Journal of Biological Chemistry60 citations Open access
Semantic Scholar
Targeted Disruption of the Mouse PAS Domain Serine/Threonine Kinase PASKIN
D. Katschinski, Hugo H. Marti, K. Wagner, J. Shibata +8 more
2003Molecular and Cellular Biology44 citations Open access
Semantic Scholar
Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3
P. Cinelli, Elisa A. Casanova, Syndi Uhlig, Priska Lochmatter +5 more
2008BMC Developmental Biology42 citations Open access
Semantic Scholar
Evaluation of In Vitro Cultured Rat Oocytes, from Different Strains, by Spindle Morphology and Maturation-Promoting-Factor Activity Combined with Nuclear-Transfer Experiments
Oliver Sterthaus, E. Skoczylas, C. de Geyter, K. Bürki +1 more
2009Cloning and Stem Cells25 citations Open access
Semantic Scholar
Trophoblast Cell-Specific Carcinoembryonic Antigen Cell Adhesion Molecule 9 Is Not Required for Placental Development or a Positive Outcome of Allotypic Pregnancies
Daniela Finkenzeller, B. Fischer, J. Mclaughlin, Heinrich Schrewe +2 more
2000Molecular and Cellular Biology16 citations Open access
Semantic Scholar
Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice
G. Korner, Tanja Scherer, D. Adamsen, A. Rebuffat +19 more
2016Journal of Inherited Metabolic Disease12 citations Open access
Semantic Scholar
TRANSGENIC ANIMALS AS PHARMACOLOGICAL TOOLS
K. Bürki, B. Ledermann
199510 citations
Semantic Scholar
Magnetic resonance imaging and ultrasound elastography in the context of preclinical pharmacological research: significance for the 3R principles
M. Obrecht, S. Zurbruegg, N. Accart, Christian Lambert +3 more
2023Frontiers in Pharmacology7 citations Open access
Semantic Scholar
Establishment of embryonic stem cell lines
B. Ledermann
19967 citations
Semantic Scholar
Survival of islet grafts in perforin-deficient mice.
X. Lu, B. Ledermann, J. Borel
1995Transplantation Proceedings7 citations
Semantic Scholar
Title Expression profiling in transgenic FVB / N embryonic stem cellsoverexpressing STAT 3 . Author ( s )
P. Cinelli, Syndi Uhlig, Priska Lochmatter, Elisa A. Casanova +5 more
20170 citations
Semantic Scholar
Genetic inactivation of a specific PP2A subunit, PR61/B'delta, in a mouse model generates tauopathy through an indirect mechanism
J. Louis, E. Martens, P. Borghgraef, Sari Longin +10 more
20100 citations
Semantic Scholar
Ethics Committee for Animal Studies. Interspecies crosses: aspects of animal protection
M. Geiser, A. Steiger, C. A. der Au, B. Baertschi +18 more
20090 citations
Semantic Scholar
Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3
P. Cinelli, Elisa A. Casanova, Syndi Uhlig, Priska Lochmatter +5 more
20090 citations
Semantic Scholar
Neurological analysis of mice lacking a regulatory subunit B’/PR61delta containing Protein phosphatase 2A
J. Louis, E. Martens, P. Borghgraef, Sari Longin +8 more
20080 citations
Semantic Scholar
Tau hyperphosphorylation in PP2A-PR61delta knockout mice
J. Louis, E. Martens, K. Zwaenepoel, Sari Longin +7 more
20070 citations
Semantic Scholar
Reveal a Protective Role for IL-13 Receptor-Deficient Mice in Chronic Leishmaniasis α Differences Between IL-4-and IL-4 Receptor
M. Mohrs, B. Ledermann, G. Köhler, Andreas Dorfmüller +2 more
19990 citations
Semantic Scholar

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