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J. Toppari · SciRah

Researcher profile · Semantic Scholar

J. Toppari

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J. Toppari — researcher profile on SciRah

h-index: 100
Works: 706
Citations: 43K

Most-cited papers

Environmental toxicants and male fertility.
W. Rodprasert, J. Toppari, H. Virtanen
2022Best Practice & Research: Clinical Obstetrics & Gynaecology54 citations Open access
Semantic Scholar
Two-age islet-autoantibody screening for childhood type 1 diabetes: a prospective cohort study
Mohamed Ghalwash, J. Dunne, M. Lundgren, M. Rewers +5 more
2022The Lancet Diabetes and Endocrinology49 citations Open access
Semantic Scholar
Plasma protein biomarkers predict the development of persistent autoantibodies and type 1 diabetes 6 months prior to the onset of autoimmunity
E. Nakayasu, L. Bramer, C. Ansong, A. Schepmoes +21 more
2023Cell Reports Medicine37 citations Open access
Semantic Scholar
Incidence of Pediatric Celiac Disease Varies by Region
M. Stahl, Qian Li, Kristian F. Lynch, S. Koletzko +15 more
2022American Journal of Gastroenterology37 citations Open access
Semantic Scholar
INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes
David B. Dunger, S. Bruggraber, A. Mander, M. Marcovecchio +135 more
2022Trials37 citations Open access
Semantic Scholar
Clinical care advice for monitoring of islet autoantibody positive individuals with presymptomatic type 1 diabetes
A. Hendriks, M. Marcovecchio, R. Besser, E. Bonifacio +13 more
2024Diabetes/Metabolism Research Reviews36 citations Open access
Semantic Scholar
Temporal changes in gastrointestinal fungi and the risk of autoimmunity during early childhood: the TEDDY study
T. Auchtung, C. Stewart, Daniel Patrick Smith, E. Triplett +13 more
2022Nature Communications36 citations Open access
Semantic Scholar
Progression of type 1 diabetes from latency to symptomatic disease is predicted by distinct autoimmune trajectories
Bum Chul Kwon, V. Anand, P. Achenbach, J. Dunne +9 more
2022Nature Communications36 citations Open access
Semantic Scholar
Heterogeneity of DKA Incidence and Age-Specific Clinical Characteristics in Children Diagnosed With Type 1 Diabetes in the TEDDY Study.
Laura M. Jacobsen, K. Vehik, R. Veijola, K. Warncke +12 more
2022Diabetes Care35 citations Open access
Semantic Scholar
Cryptorchidism and puberty
W. Rodprasert, H. Virtanen, J. Toppari
2024Frontiers in Endocrinology27 citations Open access
Semantic Scholar
Islet autoantibody screening in at-risk adolescents to predict type 1 diabetes until young adulthood: a prospective cohort study
Mohamed Ghalwash, V. Anand, Olivia Lou, F. Martin +5 more
2023The Lancet Child & Adolescent Health27 citations Open access
Semantic Scholar
Looking back at the TEDDY study: lessons and future directions
Å. Lernmark, D. Agardh, B. Akolkar, Patricia Gesualdo +20 more
2024Nature Reviews Endocrinology26 citations Open access
Semantic Scholar
SARS-CoV-2 — No Increased Islet Autoimmunity or Type 1 Diabetes in Teens
J. Krischer, Å. Lernmark, W. Hagopian, M. Rewers +4 more
2023New England Journal of Medicine24 citations Open access
Semantic Scholar
Physical Activity and the Development of Islet Autoimmunity and Type 1 Diabetes in 5-15-Year-Old Children Followed in the TEDDY Study.
Xiang Liu, S. B. Johnson, K. Lynch, Kerry L. Cordan +11 more
2023Diabetes Care22 citations Open access
Semantic Scholar
Rising Hemoglobin A1c in the Nondiabetic Range Predicts Progression of Type 1 Diabetes As Well As Oral Glucose Tolerance Tests.
K. Vehik, D. Boulware, Michael B Killian, M. Rewers +9 more
2022Diabetes Care22 citations Open access
Semantic Scholar
Serum Testosterone Levels in 3-Month-Old Boys Predict Their Semen Quality as Young Adults
Louise Scheutz Henriksen, J. Petersen, N. Skakkebæk, N. Jørgensen +5 more
2022Journal of Clinical Endocrinology and Metabolism22 citations Open access
Semantic Scholar
Non-HLA Gene Polymorphisms in the Pathogenesis of Type 1 Diabetes: Phase and Endotype Specific Effects
A. Laine, Milla Valta, J. Toppari, M. Knip +3 more
2022Frontiers in Immunology22 citations Open access
Semantic Scholar
Refining the Definition of Stage 1 Type 1 Diabetes: An Ontology-Driven Analysis of the Heterogeneity of Multiple Islet Autoimmunity.
Brigette I. Frohnert, Mohamed Ghalwash, Ying Li, Kenney Ng +8 more
2023Diabetes Care21 citations Open access
Semantic Scholar
Torque Teno Virus Primary Infection Kinetics in Early Childhood
E. Väisänen, I. Kuisma, Marjaana Mäkinen, J. Ilonen +4 more
2022Viruses21 citations Open access
Semantic Scholar
Maternal phthalate exposure during pregnancy and testis function of young adult sons.
L. S. Henriksen, H. Frederiksen, N. Jørgensen, A. Juul +4 more
2023Science of the Total Environment20 citations Open access
Semantic Scholar
Possible heterogeneity of initial pancreatic islet beta-cell autoimmunity heralding type 1 diabetes
Å. Lernmark, B. Akolkar, W. Hagopian, J. Krischer +5 more
2023Journal of Internal Medicine18 citations Open access
Semantic Scholar
Gene expression signature predicts rate of type 1 diabetes progression
T. Suomi, I. Starskaia, Ubaid Ullah Kalim, O. Rasool +138 more
2023EBioMedicine17 citations Open access
Semantic Scholar
Unfolding the Mystery of Autoimmunity: The Environmental Determinants of Diabetes in the Young (TEDDY) Study
M. Rewers, D. Agardh, S. Johnson, E. Bonifacio +23 more
2025Diabetes Care16 citations
Semantic Scholar
Cohort Profile Update: Expanding the Cardiovascular Risk in Young Finns Study into a multigenerational cohort
K. Pahkala, S. Rovio, N. Kartiosuo, Kari Auranen +36 more
2024medRxiv16 citations Open access
Semantic Scholar
Distinct transcriptomic profiles in children prior to the appearance of type 1 diabetes-linked islet autoantibodies and following enterovirus infection
Jake Lin, Elaheh Moradi, Karoliina Salenius, Suvi Lehtipuro +17 more
2023Nature Communications15 citations Open access
Semantic Scholar
Retinoblastoma-E2F Transcription Factor Interplay Is Essential for Testicular Development and Male Fertility
Juho-Antti Mäkelä, J. Toppari
2022Frontiers in Endocrinology15 citations Open access
Semantic Scholar
Dietary fatty acid intake in childhood and the risk of islet autoimmunity and type 1 diabetes: the DIPP birth cohort study
L. Hakola, Anna-Leena Vuorinen, H. Takkinen, S. Niinistö +9 more
2022European Journal of Nutrition14 citations Open access
Semantic Scholar
Pubertal testicular volume references for ruler, orchidometer, and ultrasonography measurements based on a longitudinal follow‐up
Mikael Koskela, H. Virtanen, W. Rodprasert, K. Jahnukainen +2 more
2024Andrology13 citations Open access
Semantic Scholar
Distinct cellular immune responses in children en route to type 1 diabetes with different first-appearing autoantibodies
I. Starskaia, Milla Valta, Sami Pietilä, T. Suomi +12 more
2024Nature Communications13 citations Open access
Semantic Scholar
Circulating metabolic signatures of rapid and slow progression to type 1 diabetes in islet autoantibody-positive children
S. Lamichhane, P. Sen, A. Dickens, Matilda Kråkström +9 more
2023Frontiers in Endocrinology13 citations Open access
Semantic Scholar
Temporal Alterations in CD8+ T Cells During the Progression from Stage 1 to Stage 3 Type 1 Diabetes.
Anna-Mari Schroderus, Viola Pitkänen, Ilse Ekman, Daniel Stevens +9 more
2024Diabetes12 citations Open access
Semantic Scholar
Association between anti-capsular IgG levels at birth and risk of invasive group B streptococcus disease in Finnish newborns: a retrospective case-control study.
A. Saukkoriipi, Natalie C. Silmon de Monerri, M. Toropainen, Laura Lindholm +9 more
2024The Lancet Microbe12 citations Open access
Semantic Scholar
Prenatal exposure to phenols and benzophenones in relation to markers of male reproductive function in adulthood
S. Holmboe, Louise Scheutz Henriksen, H. Frederiksen, A. Andersson +6 more
2022Frontiers in Endocrinology12 citations Open access
Semantic Scholar
Exploring Minimally Invasive Approach to Define Stages of Type 1 Diabetes Remotely
Helena Kontola, Inka Eveliina Alanko, J. Koskenniemi, E. Löyttyniemi +5 more
2022Diabetes Technology & Therapeutics12 citations Open access
Semantic Scholar
HbA1c as a time predictive biomarker for an additional islet autoantibody and type 1 diabetes in seroconverted TEDDY children
F. Salami, R. Tamura, Lu You, Å. Lernmark +11 more
2022Pediatric Diabetes12 citations Open access
Semantic Scholar
Quantifying the utility of islet autoantibody levels in the prediction of type 1 diabetes in children
Kenney Ng, V. Anand, Harry Stavropoulos, R. Veijola +9 more
2022Diabetologia11 citations Open access
Semantic Scholar
Dietary Intake and Body Mass Index Influence the Risk of Islet Autoimmunity in Genetically At-Risk Children: A Mediation Analysis Using the TEDDY Cohort
Carin Andrén Aronsson, R. Tamura, K. Vehik, U. Uusitalo +12 more
2023Pediatric Diabetes10 citations Open access
Semantic Scholar
Gluten-free diet adherence in children with screening-detected celiac disease using a prospective birth cohort study
Pooja Mehta, Qian Li, M. Stahl, U. Uusitalo +14 more
2023PLoS ONE10 citations Open access
Semantic Scholar
Exposure to Phthalates in European Children, Adolescents and Adults since 2005: A Harmonized Approach Based on Existing HBM Data in the HBM4EU Initiative
N. Vogel, R. Lange, Phillipp Schmidt, Laura Rodriguez Martin +44 more
2023Toxics10 citations Open access
Semantic Scholar
Continuous glucose monitor metrics from five studies identify participants at risk for type 1 diabetes development
P. Calhoun, Charles Spanbauer, A. Steck, Brigette I. Frohnert +10 more
2025Diabetologia9 citations Open access
Semantic Scholar
Islet Autoantibody Levels Differentiate Progression Trajectories in Individuals With Presymptomatic Type 1 Diabetes
Bum Chul Kwon, P. Achenbach, V. Anand, B. Frohnert +9 more
2022Diabetes9 citations Open access
Semantic Scholar
Reproductive Markers of Testicular Function and Size During Puberty in Boys With and Without a History of Cryptorchidism
W. Rodprasert, J. Koskenniemi, H. Virtanen, S. Sadov +8 more
2022Journal of Clinical Endocrinology and Metabolism9 citations Open access
Semantic Scholar
Congenital Hypothyroidism and Hyperthyroidism Alters Adrenal Gene Expression, Development, and Function
Konrad Patyra, C. Löf, H. Jaeschke, Hendrik J Undeutsch +18 more
2022Thyroid9 citations Open access
Semantic Scholar
Intake of B vitamins and the risk of developing islet autoimmunity and type 1 diabetes in the TEDDY study
L. Hakola, Lazarus K. Mramba, U. Uusitalo, Carin Andrén Aronsson +15 more
2024European Journal of Nutrition8 citations Open access
Semantic Scholar
Gastrointestinal Infections Modulate the Risk for Insulin Autoantibodies as the First-Appearing Autoantibody in the TEDDY Study.
M. Lönnrot, K. Lynch, M. Rewers, Å. Lernmark +10 more
2023Diabetes Care8 citations Open access
Semantic Scholar
Evaluation of plasma IL-21 as a potential biomarker for type 1 diabetes progression
Anna-Mari Schroderus, J. Poorbaugh, S. McElyea, S. Beasley +10 more
2023Frontiers in Immunology8 citations Open access
Semantic Scholar
Effect of Previous Alkylating Agent Exposure on Follicle Numbers in Cryopreserved Prepubertal and Young Adult Ovarian Tissue after Long-Term Xenografting
M. Nurmio, B. Asadi-Azarbaijani, M. Hou, R. Kiviö +5 more
2022Cancers8 citations Open access
Semantic Scholar
Early‐pregnancy BMI, maternal gestational weight gain, and asthma and allergic diseases in children
Vincent Ojwang', B. Nwaru, Takkinen Hanna-Mari, Tapanainen Heli +10 more
2024Pediatric Allergy and Immunology7 citations Open access
Semantic Scholar
Fruit, berry, and vegetable consumption and the risk of islet autoimmunity and type 1 diabetes in children—the Type 1 Diabetes Prediction and Prevention birth cohort study
Markus Mattila, H. Takkinen, Essi J. Peltonen, Anna-Leena Vuorinen +11 more
2023American Journal of Clinical Nutrition7 citations Open access
Semantic Scholar
Longitudinal consumption of fruits and vegetables and risk of asthma by 5 years of age
Johanna Metsälä, Anna-Leena Vuorinen, H. Takkinen, Essi J. Peltonen +11 more
2023Pediatric Allergy and Immunology7 citations Open access
Semantic Scholar

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