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F. Claessens · SciRah

Researcher profile · Semantic Scholar

F. Claessens

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F. Claessens — researcher profile on SciRah

h-index: 64
Works: 341
Citations: 19K

Most-cited papers

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
F. Schumacher, A. A. Al Olama, S. Berndt, S. Benlloch +183 more
2018Nature Genetics808 citations Open access
Semantic Scholar
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction
D. Conti, B. Darst, Lilit C. Moss, E. Saunders +227 more
2021Nature Genetics407 citations Open access
Semantic Scholar
Large-scale transcriptome-wide association study identifies new prostate cancer risk regions
N. Mancuso, S. Gayther, Alexander Gusev, Wei Zheng +70 more
2018Nature Communications145 citations Open access
Semantic Scholar
Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma
M. Went, A. Sud, A. Försti, Britta Halvarsson +127 more
2018Nature Communications108 citations Open access
Semantic Scholar
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants
Tokhir Dadaev, E. Saunders, P. Newcombe, Ezequiel Anokian +306 more
2018Nature Communications105 citations Open access
Semantic Scholar
Shared heritability and functional enrichment across six solid cancers
Xia Jiang, H. Finucane, F. Schumacher, S. Schmit +329 more
2019Nature Communications104 citations Open access
Semantic Scholar
Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse
S. Taavitsainen, N. Engedal, S. Cao, F. Handle +29 more
2021Nature Communications103 citations Open access
Semantic Scholar
Neoadjuvant hormonal therapy before radical prostatectomy in high-risk prostate cancer
G. Devos, W. Devlies, G. De Meerleer, M. Baldewijns +8 more
2021Nature reviews. Urology96 citations
Semantic Scholar
Role of sex hormone-binding globulin in the free hormone hypothesis and the relevance of free testosterone in androgen physiology
N. Narinx, K. David, J. Walravens, P. Vermeersch +5 more
2022Cellular and Molecular Life Sciences83 citations Open access
Semantic Scholar
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight
Maria LC Bin James E Rodrigo M Marisa K Andrea Honor Bet Iurilli Zhou Bennett Carrillo-Larco Sophiea Rodrig, M. L. Iurilli, Bin Zhou, J. Bennett +496 more
2021eLife76 citations Open access
Semantic Scholar
ARNEO: A Randomized Phase II Trial of Neoadjuvant Degarelix with or Without Apalutamide Prior to Radical Prostatectomy for High-risk Prostate Cancer.
G. Devos, L. Tosco, M. Baldewijns, T. Gevaert +14 more
2022European Urology74 citations Open access
Semantic Scholar
Drivers of AR indifferent anti-androgen resistance in prostate cancer cells
F. Handle, S. Preković, C. Helsen, T. Van den Broeck +9 more
2019Scientific Reports68 citations Open access
Semantic Scholar
Polygenic hazard score is associated with prostate cancer in multi-ethnic populations
M. Huynh-Le, Chun-Chieh Fan, R. Karunamuni, W. Thompson +74 more
2020Nature Communications64 citations Open access
Semantic Scholar
National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries
Cristina Rod Bin Honor Goodarz Mariachiara Kari Kaveh James Taddei Jackson Zhou Bixby Danaei Di Cesare Kuulasm, C. Taddei, R. Jackson, Bin Zhou +358 more
2019International Journal of Epidemiology58 citations Open access
Semantic Scholar
Testosterone boosts physical activity in male mice via dopaminergic pathways
F. Jardi, M. Laurent, Nari Kim, Rougin Khalil +12 more
2018Scientific Reports47 citations Open access
Semantic Scholar
A kindred with Mutant IKAROS and autoimmunity.
Erika Van Nieuwenhove, J. Garcia-Perez, C. Helsen, Princess Rodriguez +13 more
2018Journal of Allergy and Clinical Immunology41 citations Open access
Semantic Scholar
Defective Sec61α1 underlies a novel cause of autosomal dominant severe congenital neutropenia
Erika Van Nieuwenhove, John S. Barber, Julika Neumann, E. Smeets +26 more
2020Journal of Allergy and Clinical Immunology38 citations Open access
Semantic Scholar
Genetically proxied glucose-lowering drug target perturbation and risk of cancer: a Mendelian randomisation analysis
J. Yarmolinsky, E. Bouras, Andrei-Emil Constantinescu, K. Burrows +91 more
2023Diabetologia36 citations Open access
Semantic Scholar
The androgen receptor depends on ligand‐binding domain dimerization for transcriptional activation
Sarah El Kharraz, V. Dubois, Martin E. Royen, A. Houtsmuller +21 more
2021EMBO Reports34 citations Open access
Semantic Scholar
Bone health in ageing men
K. David, N. Narinx, L. Antonio, P. Evenepoel +3 more
2022Reviews in Endocrine & Metabolic Disorders31 citations Open access
Semantic Scholar
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia
J. Vijayakrishnan, J. Studd, P. Broderick, B. Kinnersley +92 more
2018Nature Communications31 citations Open access
Semantic Scholar
Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites
Marina Kulik, M. Bothe, Gözde Kibar, Alisa Fuchs +8 more
2020bioRxiv30 citations Open access
Semantic Scholar
Validation of the Decipher Test for Predicting Distant Metastatic Recurrence in Men with High-risk Nonmetastatic Prostate Cancer 10 Years After Surgery.
T. Van den Broeck, L. Moris, T. Gevaert, L. Tosco +16 more
2019European Urology Oncology29 citations Open access
Semantic Scholar
Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score
M. Huynh-Le, R. Karunamuni, Chun-Chieh Fan, Lui Asona +71 more
2022Prostate Cancer and Prostatic Diseases28 citations Open access
Semantic Scholar
Preclinical Models in Prostate Cancer: Resistance to AR Targeting Therapies in Prostate Cancer
W. Devlies, F. Handle, G. Devos, S. Joniau +1 more
2021Cancers27 citations Open access
Semantic Scholar
Tumor characteristics and outcome by androgen receptor expression in triple-negative breast cancer patients treated with neo-adjuvant chemotherapy
L. Jongen, G. Floris, H. Wildiers, F. Claessens +9 more
2019Breast Cancer Research and Treatment24 citations
Semantic Scholar
Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer
R. Karunamuni, M. Huynh-Le, C. Fan, W. Thompson +61 more
2021Prostate Cancer and Prostatic Diseases22 citations Open access
Semantic Scholar
The CHEK2 Variant C.349A>G Is Associated with Prostate Cancer Risk and Carriers Share a Common Ancestor
Andreia Brandão, P. Paulo, S. Maia, M. Pinheiro +57 more
2020Cancers22 citations Open access
Semantic Scholar
Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry.
B. Darst, Jiayi Shen, R. Madduri, Alexis A. Rodriguez +104 more
2023American Journal of Human Genetics20 citations Open access
Semantic Scholar
Testosterone Reduces Body Fat in Male Mice by Stimulation of Physical Activity Via Extrahypothalamic ERα Signaling
Na Ri Kim, K. David, Katrien Corbeels, Rougin Khalil +11 more
2021Endocrinology20 citations Open access
Semantic Scholar
Germline variation at 8q24 and prostate cancer risk in men of European ancestry
M. Matejcic, E. Saunders, Tokhir Dadaev, M. Brook +300 more
2018Nature Communications19 citations Open access
Semantic Scholar
Preoperative Risk-Stratification of High-Risk Prostate Cancer: A Multicenter Analysis
B. Chys, G. Devos, W. Everaerts, M. Albersen +19 more
2020Frontiers in Oncology18 citations Open access
Semantic Scholar
Clinical Actionability of the Genomic Landscape of Metastatic Castration Resistant Prostate Cancer
W. Devlies, M. Eckstein, A. Cimadamore, G. Devos +6 more
2020Cells18 citations Open access
Semantic Scholar
Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
F. Schumacher, Ali Olama, S. Berndt, S. Benlloch +183 more
2019Nature Genetics17 citations Open access
Semantic Scholar
Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice
Rodanthi Lyraki, Anaëlle Grabek, Amélie Tison, Lahiru Chamara Weerasinghe Arachchige +8 more
2023Disease Models & Mechanisms15 citations Open access
Semantic Scholar
Androgen Receptor in Neurons Slows Age‐Related Cortical Thinning in Male Mice
F. Jardi, Nari Kim, M. Laurent, Rougin Khalil +7 more
2019Journal of Bone and Mineral Research15 citations Open access
Semantic Scholar
Testosterone Restores Body Composition, Bone Mass, and Bone Strength Following Early Puberty Suppression in a Mouse Model Mimicking the Clinical Strategy in Trans Boys
V. Dubois, Silvia Ciancia, Stefanie Doms, Sarah El Kharraz +12 more
2023Journal of Bone and Mineral Research14 citations Open access
Semantic Scholar
A disease‐associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer
E. Smeets, Shengyun Huang, Xiao Yin Lee, Erika Van Nieuwenhove +15 more
2022Journal of Cachexia, Sarcopenia and Muscle14 citations Open access
Semantic Scholar
Genito-urinary genomics and emerging biomarkers for immunomodulatory cancer treatment.
T. Gevaert, R. Montironi, A. López-Beltran, G. V. van Leenders +8 more
2018Seminars in Cancer Biology14 citations Open access
Semantic Scholar
Androgen and estrogen actions on male physical activity: a story beyond muscle.
F. Jardi, M. Laurent, V. Dubois, Nari Kim +4 more
2018Journal of Endocrinology14 citations Open access
Semantic Scholar
Early effects of androgen deprivation on bone and mineral homeostasis in adult men: a prospective cohort study.
Rougin Khalil, L. Antonio, M. Laurent, K. David +9 more
2020European Journal of Endocrinology13 citations Open access
Semantic Scholar
The potential of tumour microenvironment markers to stratify the risk of recurrence in prostate cancer patients
T. Gevaert, Y. Van Eycke, Thomas Vanden Broeck, H. Van Poppel +7 more
2020PLoS ONE12 citations Open access
Semantic Scholar
Exploiting ligand binding domain dimerization for development of novel androgen receptor inhibitors.
C. Helsen, T. Nguyen, Xiao Yin Lee, R. Eerlings +5 more
2022Molecular Cancer Therapeutics11 citations Open access
Semantic Scholar
Novel model to study the physiological effects of temporary or prolonged sex steroid deficiency in male mice.
Na Ri Kim, Rougin Khalil, K. David, L. Antonio +9 more
2020American Journal of Physiology. Endocrinology and Metabolism11 citations Open access
Semantic Scholar
Androgen action on renal calcium and phosphate handling: Effects of bisphosphonate treatment and low calcium diet.
Rougin Khalil, I. Simitsidellis, Na Ri Kim, F. Jardi +7 more
2020Molecular and Cellular Endocrinology11 citations Open access
Semantic Scholar
Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry
B. Darst, Jiayi Shen, R. Madduri, Alexis A. Rodriguez +103 more
2023medRxiv10 citations Open access
Semantic Scholar
Neoadjuvant treatment with androgen receptor signaling inhibitors prior to radical prostatectomy: a systematic review
G. Devos, B. Vansevenant, G. De Meerleer, A. Clinckaert +8 more
2021World journal of urology10 citations Open access
Semantic Scholar
Estrogen receptor alpha signaling in extrahypothalamic neurons during late puberty decreases bone size and strength in female but not in male mice
Na Ri Kim, F. Jardi, Rougin Khalil, L. Antonio +11 more
2020The FASEB Journal10 citations Open access
Semantic Scholar
Estradiol and Age-Related Bone Loss in Men.
F. Jardi, M. Laurent, F. Claessens, D. Vanderschueren
2018Physiological Reviews10 citations
Semantic Scholar
Structural mechanism underlying variations in DNA binding by the androgen receptor.
X. Lee, Wout Van Eynde, C. Helsen, H. Willems +4 more
2024Journal of Steroid Biochemistry and Molecular Biology8 citations Open access
Semantic Scholar

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