Kuan-Can Liu

Most-cited papers

1. The multiple roles for Sox2 in stem cell maintenance and tumorigenesis

   Kuan-Can Liu, Bao-Shun Lin, Meng Zhao, Xiang-Yue Yang +4 more

   2013Cellular Signalling270 citations Open access

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2. Transitional basal cells at the squamous-columnar junction generate Barrett’s oesophagus

   M. Jiang, Haiyan Li, Yong-Chun Zhang, Ying Yang +22 more

   2017Nature206 citations Open access

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3. Sox2 Cooperates with Inflammation-Mediated Stat3 Activation in the Malignant Transformation of Foregut Basal Progenitor Cells

   Kuan-Can Liu, M. Jiang, Yun Lu, Hao Chen +12 more

   2013Cell Stem Cell190 citations Open access

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4. SOX2 regulates multiple malignant processes of breast cancer development through the SOX2/miR-181a-5p, miR-30e-5p/TUSC3 axis

   Kuan-Can Liu, Fu'an Xie, An-Ding Gao, Rui Zhang +10 more

   2017Molecular Cancer106 citations Open access

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5. BMP-driven NRF2 activation in esophageal basal cell differentiation and eosinophilic esophagitis.

   M. Jiang, W. Ku, Zhong-Ren Zhou, E. Dellon +9 more

   2015Journal of Clinical Investigation97 citations Open access

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6. Etiology, Cancer Stem cells and Potential Diagnostic Biomarkers for Esophageal Cancer

   Kuan-Can Liu, T. Zhao, Junkai Wang, Yun-Yun Chen +3 more

   2019Cancer Letters93 citations Open access

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7. Development and Stem Cells of the Esophagus

   Yong-Chun Zhang, M. Jiang, Eugene Kim, Sijie Lin +3 more

   2016Seminars in Cell and Developmental Biology84 citations Open access

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8. The Wnt signaling pathway in tumorigenesis, pharmacological targets, and drug development for cancer therapy

   Zhuo Wang, T. Zhao, Shihui Zhang, Junkai Wang +6 more

   2021Biomarker Research49 citations Open access

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9. Targeting SOX2 Protein with Peptide Aptamers for Therapeutic Gains against Esophageal Squamous Cell Carcinoma.

   Kuan-Can Liu, Fu'an Xie, T. Zhao, Rui Zhang +15 more

   2020Molecular Therapy46 citations Open access

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10. Aptamers: A promising tool for cancer imaging, diagnosis, and therapy

    Kuan-Can Liu, Bao-Shun Lin, X. Lan

    2013Journal of Cellular Biochemistry42 citations

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11. Pharmacological targeting of p38 MAP-Kinase 6 (MAP2K6) inhibits the growth of esophageal adenocarcinoma.

    Sijie Lin, Kuan-Can Liu, Yong-Chun Zhang, M. Jiang +8 more

    2018Cellular Signalling29 citations

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12. C4-HSL aptamers for blocking qurom sensing and inhibiting biofilm formation in Pseudomonas aeruginosa and its structure prediction and analysis

    Meng Zhao, WeiBin Li, Kuan-Can Liu, Huiling Li +1 more

    2019PLoS ONE20 citations Open access

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13. HPV16 infection promotes the malignant transformation of the esophagus and progression of esophageal squamous cell carcinoma

    Hongzhou Zhao, Yuxuan Wei, Jiaying Zhang, Kun Zhang +13 more

    2023Journal of Medical Virology16 citations

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14. Development of a novel ssDNA aptamer targeting neutrophil gelatinase-associated lipocalin and its application in clinical trials

    Xiao-Qian Hong, Hui-Hui Yan, Fu'an Xie, Kai-Yu Wang +9 more

    2019Journal of Translational Medicine14 citations Open access

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15. Agaricus blazei murrill and Enteromorpha prolifera-derived polysaccharides gain therapeutic effects on esophageal squamous cell carcinoma

    Yong Lin, Xinxin Li, Jing Zhao, Peng-Hu Liu +16 more

    2024Journal of Functional Foods12 citations Open access

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16. SOX2 inhibits LLGL2 polarity protein in esophageal squamous cell carcinoma via miRNA-142-3p

    Shihui Zhang, Yun-Yun Chen, Qiong Hu, T. Zhao +12 more

    2022Cancer Biology & Therapy12 citations Open access

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17. Use of a Novel Integrase-Deficient Lentivirus for Targeted Anti-Cancer Therapy With Survivin Promoter-Driven Diphtheria Toxin A

    Bao-Shun Lin, An-Ding Gao, Rui Zhang, Hong Ma +6 more

    2015Medicine12 citations Open access

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18. Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy

    Yong-Chun Zhang, Dimitris Karagiannis, Helu Liu, Mi Lin +20 more

    2024Science Advances11 citations Open access

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19. The roles of the SOX2 protein in the development of esophagus and esophageal squamous cell carcinoma, and pharmacological target for therapy.

    Jiaying Zhang, Zhuo Wang, Hongzhou Zhao, Yuxuan Wei +6 more

    2023Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie10 citations Open access

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20. Targeting the SOX2/PARP1 complex to intervene in the growth of esophageal squamous cell carcinoma.

    Zhuo Wang, Junkai Wang, Hongzhou Zhao, T. Zhao +13 more

    2022Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie10 citations Open access

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21. Targeting the SOX2/CDP protein complex with a peptide suppresses the malignant progression of esophageal squamous cell carcinoma

    Yun-Yun Chen, Kun Zhang, Rui Zhang, Zhuo Wang +15 more

    2023Cell Death Discovery8 citations Open access

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22. The advancements in organoids: Potential and challenges in researching the esophagus and esophageal squamous cell carcinoma

    Xinxin Li, Zhuo Wang, Yongpan Liu, Jiaying Zhang +7 more

    2025Genes and Diseases6 citations

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23. Chelerythrine inhibits esophageal squamous cell carcinoma progression via PINK1-Parkin-mediated mitophagy

    Yijian Zhou, Zhuo Wang, Hongzhou Zhao, Yongpan Liu +10 more

    2025Journal of Translational Medicine5 citations Open access

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24. Long cruising aptamer-albumin nanobots intelligently capture and restrain circulating tumor cells

    Jie Wang, Huo Xu, Shuhui Li, Min Lin +5 more

    2023Nano Today4 citations Open access

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25. Basal progenitor cells bridge the development, malignant cancers, and multiple diseases of esophagus

    Bao-Shun Lin, Fu'an Xie, Zhangwu Xiao, Xiao-Qian Hong +2 more

    2018Journal of Cellular Physiology3 citations

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26. Potential biomarkers develop for predicting the prognosis of patients with esophageal squamous cell carcinoma after optimized chemoradiotherapy using serum metabolomics

    Jie Yang, Yunyun Zhu, Yijian Zhou, Jiaying Zhang +11 more

    2025BMC Cancer2 citations Open access

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27. Polymerization-driven successive collapse of DNA dominoes enabling highly sensitive cancer gene diagnosis.

    Haiyan Dong, Bo Lu, Jie Wang, Jingjing Xie +3 more

    2019Chemical Communications2 citations

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28. Biomarkers for oesophageal squamous cell carcinoma and the role of HPV: Multi-omics approaches and current evidence (Review)

    Limin Zou, Hongzhou Zhao, Jiaying Zhang, Jialing Xie +6 more

    2026International Journal of Oncology1 citations Open access

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29. Selection and validation of a cell-internalizing DNA aptamer targeting esophageal squamous cell carcinoma.

    Kun-Rong Yang, Zhenzhou Xiao, R. Huo, Zhaolei Cui +7 more

    2025European Journal of Pharmacology1 citations

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30. Cloning and characteristics of a novel gene HbUEP from latex in Hevea brasiliensis

    Yun Yang, Zhi-Li Zhang, Kuan-Can Liu, Wei-Guo Li +1 more

    20081 citations

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31. Diagnostic and therapeutic potential of RNA m6A methylation in oesophageal squamous cell carcinoma

    Bo Zhang, Yongpan Liu, Hongzhou Zhao, Jialing Xie +5 more

    2026Genes & Diseases0 citations Open access

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32. The Wnt signaling pathway in tumorigenesis, pharmacological targets, and drug development for cancer therapy

    Zhuo Wang, T. Zhao, Shihui Zhang, Junkai Wang +6 more

    2021Biomarker Research0 citations Open access

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33. [Establishment of esophageal squamous carcinoma cell lines stably over-expressing LLGL2].

    Qiong Hu, Fu'an Xie, Xiao-Qian Hong, Kuan-Can Liu

    2017Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology0 citations

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34. Involvement of epithelial stem cells in malignant transformation and mechanisms

    Shihui Zhang, Qiong Hu, Fu'an Xie, Xiao-Qian Hong +1 more

    20170 citations

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35. A Rapid and Efficient Protocol for Total RNA Isolation from Latex of Hevea brasiliensis

    Zhili Zhang, Yun-Lin Yang, Kuan-Can Liu, Huo-Sheng Su

    2007植物学通报0 citations

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36. 一种快速、高效的橡胶树胶乳总RNA 提取方法

    Yun-Lin Yang, Zhi-Li Zhang, Kuan-Can Liu, Huo-Sheng Su

    20070 citations

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