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A. Castilho · SciRah

Researcher profile · Semantic Scholar

A. Castilho

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A. Castilho — researcher profile on SciRah

h-index: 28
Works: 64
Citations: 2,493

Most-cited papers

In Planta Protein Sialylation through Overexpression of the Respective Mammalian Pathway
A. Castilho, R. Strasser, J. Stadlmann, J. Grass +8 more
2010Journal of Biological Chemistry212 citations Open access
Semantic Scholar
Improved Virus Neutralization by Plant-produced Anti-HIV Antibodies with a Homogeneous β1,4-Galactosylated N-Glycan Profile*
R. Strasser, A. Castilho, J. Stadlmann, R. Kunert +7 more
2009Journal of Biological Chemistry168 citations Open access
Semantic Scholar
N-Glycosylation engineering of plants for the biosynthesis of glycoproteins with bisected and branched complex N-glycans
A. Castilho, Pia Gattinger, J. Grass, Jakub Jeż +5 more
2011Glycobiology138 citations Open access
Semantic Scholar
Physical mapping of 5S and 18S-25S rDNA and repetitive DNA sequences in Aegilops umbellulata.
A. Castilho, J. Heslop-Harrison
1995Genome120 citations
Semantic Scholar
N-glycosylation of plant-produced recombinant proteins.
D. Bosch, A. Castilho, A. Loos, A. Schots +1 more
2013Current pharmaceutical design118 citations Open access
Semantic Scholar
Engineering of complex protein sialylation in plants
Somanath Kallolimath, A. Castilho, R. Strasser, C. Grünwald-Gruber +11 more
2016Proceedings of the National Academy of Sciences of the United States of America104 citations Open access
Semantic Scholar
Retroelements, transposons and methylation status in the genome of oil palm (Elaeis guineensis) and the relationship to somaclonal variation
S. Kubis, A. Castilho, A. Vershinin, J. Heslop-Harrison
2003Plant Molecular Biology101 citations
Semantic Scholar
Engineering of Sialylated Mucin-type O-Glycosylation in Plants
A. Castilho, Laura Neumann, S. Daskalova, H. Mason +3 more
2012Journal of Biological Chemistry86 citations Open access
Semantic Scholar
Generation of Biologically Active Multi-Sialylated Recombinant Human EPOFc in Plants
A. Castilho, Laura Neumann, Pia Gattinger, R. Strasser +4 more
2013PLoS ONE82 citations Open access
Semantic Scholar
Widely separated multiple transgene integration sites in wheat chromosomes are brought together at interphase.
R. Abranches, Ana Paula Santos, E. Wegel, Sarah Williams +4 more
2000The Plant Journal81 citations
Semantic Scholar
Construction of a Functional CMP-Sialic Acid Biosynthesis Pathway in Arabidopsis1[OA]
A. Castilho, M. Pabst, R. Léonard, Christiane Veit +5 more
2008Plant Physiology79 citations Open access
Semantic Scholar
Rapid High Yield Production of Different Glycoforms of Ebola Virus Monoclonal Antibody
A. Castilho, N. Bohorova, J. Grass, O. Bohorov +4 more
2011PLoS ONE68 citations Open access
Semantic Scholar
Proteolytic and N-Glycan Processing of Human α1-Antitrypsin Expressed in Nicotiana benthamiana1[C][W][OPEN]
A. Castilho, Markus Windwarder, Pia Gattinger, L. Mach +3 more
2014Plant Physiology60 citations Open access
Semantic Scholar
5-Methylcytosine distribution and genome organization in triticale before and after treatment with 5-azacytidine.
A. Castilho, N. Neves, M. Rufini-Castiglione, Wanda Viegas +1 more
1999Journal of Cell Science57 citations
Semantic Scholar
Processing of complex N-glycans in IgG Fc-region is affected by core fucosylation
A. Castilho, Clemens Gruber, A. Thader, C. Oostenbrink +3 more
2015mAbs56 citations Open access
Semantic Scholar
Reduced paucimannosidic N‐glycan formation by suppression of a specific β‐hexosaminidase from Nicotiana benthamiana
Yun-Ji Shin, A. Castilho, Martina Dicker, Flávio Sádio +6 more
2016Plant Biotechnology Journal54 citations Open access
Semantic Scholar
An oligosaccharyltransferase from Leishmania major increases the N‐glycan occupancy on recombinant glycoproteins produced in Nicotiana benthamiana
A. Castilho, Gernot Beihammer, C. Pfeiffer, Kathrin Göritzer +7 more
2018Plant Biotechnology Journal53 citations Open access
Semantic Scholar
Expression of Antibody Fragments with a Controlled N-Glycosylation Pattern and Induction of Endoplasmic Reticulum-Derived Vesicles in Seeds of Arabidopsis1[C][W][OA]
A. Loos, B. van Droogenbroeck, S. Hillmer, J. Grass +8 more
2011Plant Physiology53 citations Open access
Semantic Scholar
Expression of functionally active sialylated human erythropoietin in plants
Jakub Jeż, A. Castilho, J. Grass, K. Vorauer-Uhl +3 more
2013Biotechnology Journal50 citations Open access
Semantic Scholar
Expression of human butyrylcholinesterase with an engineered glycosylation profile resembling the plasma-derived orthologue
Jeannine D. Schneider, A. Castilho, Laura Neumann, F. Altmann +4 more
2013Biotechnology Journal50 citations Open access
Semantic Scholar
Repetitive DNA and the Chromosomes in the Genome of Oil Palm ( Elaeis guineensis )
A. Castilho, A. Vershinin, J. Heslop-Harrison
200045 citations
Semantic Scholar
Characterization of plants expressing the human β1,4-galactosyltrasferase gene
Jeannine D. Schneider, A. Castilho, M. Pabst, F. Altmann +5 more
2015Plant physiology and biochemistry : PPB39 citations Open access
Semantic Scholar
Oligomerization status influences subcellular deposition and glycosylation of recombinant butyrylcholinesterase in Nicotiana benthamiana
Jeannine D. Schneider, S. Marillonnet, A. Castilho, Clemens Gruber +5 more
2014Plant Biotechnology Journal39 citations Open access
Semantic Scholar
Review Stepping Stones in Dna Sequencing Review Recent Advances in Targeted Genome Engineering in Mammalian Systems Review Glyco-engineering in Plants to Produce Human-like N-glycan Structures Review Using Storage Organelles for the Accumulation and Encapsulation of Recombinant Proteins the Challeng
H. Stranneheim, J. Lundeberg, N. Sun, Z. Abil +21 more
39 citations
Semantic Scholar
Engineering the interactions between a plant‐produced HIV antibody and human Fc receptors
Szymon Stelter, Mathew J. Paul, A. Y. Teh, Melanie Grandits +6 more
2019Plant Biotechnology Journal33 citations Open access
Semantic Scholar
Chromosome markers in the tetraploid wheat Aegilops ventricosa analysed by in situ hybridization
D. Bardsley, Angeles Cuadrado, P. Jack, G. Harrison +2 more
1999Theoretical and Applied Genetics31 citations
Semantic Scholar
Generation of enzymatically competent SARS‐CoV‐2 decoy receptor ACE2‐Fc in glycoengineered Nicotiana benthamiana
A. Castilho, Jennifer Schwestka, Nikolaus F. Kienzl, U. Vavra +12 more
2021Biotechnology Journal29 citations Open access
Semantic Scholar
BGAL1 depletion boosts the level of β‐galactosylation of N‐ and O‐glycans in N. benthamiana
R. Kriechbaum, Esmaiel Ziaee, C. Grünwald-Gruber, Pierre Buscaill +2 more
2019Plant Biotechnology Journal28 citations Open access
Semantic Scholar
The transmembrane domain of N –acetylglucosaminyltransferase I is the key determinant for its Golgi subcompartmentation
J. Schoberer, Eva Liebminger, U. Vavra, Christiane Veit +7 more
2014The Plant Journal27 citations Open access
Semantic Scholar
Biologically active, magnICON®-expressed EPO-Fc from stably transformed Nicotiana benthamiana plants presenting tetra-antennary N-glycan structures.
Bieke Nagels, E. V. van Damme, N. Callewaert, L. Zabeau +5 more
2012Journal of Biotechnology25 citations
Semantic Scholar
Proteolytic and N -Glycan Processing of Human Alpha-1 Antitrypsin Expressed in Nicotiana benthamiana
A. Castilho, Markus Windwarder, Pia Gattinger, L. Mach +4 more
201424 citations
Semantic Scholar
Significant Impact of Single N-Glycan Residues on the Biological Activity of Fc-based Antibody-like Fragments
Jakub Jeż, Bernhard Antes, A. Castilho, M. Kainer +5 more
2012Journal of Biological Chemistry24 citations Open access
Semantic Scholar
In Planta Glycan Engineering and Functional Activities of IgE Antibodies
Laura Montero-Morales, Daniel Maresch, Silvia Crescioli, A. Castilho +5 more
2019Frontiers in Bioengineering and Biotechnology22 citations Open access
Semantic Scholar
Physical mapping of translocation breakpoints in a set of wheat-Aegilops umbellulata recombinant lines using in situ hybridization
A. Castilho, T. E. Miller, J. Heslop-Harrison
1996Theoretical and Applied Genetics22 citations
Semantic Scholar
Molecular cloning and heterologous expression of beta1,2-xylosyltransferase and core alpha1,3-fucosyltransferase from maize.
J. S. Bondili, A. Castilho, L. Mach, J. Glössl +3 more
2006Phytochemistry21 citations
Semantic Scholar
Genomic interactions: gene expression, DNA methylation and nuclear architecture
N. Neves, A. Castilho, Manuela Silva, J. Heslop-Harrison +1 more
199721 citations
Semantic Scholar
Promoter Choice Impacts the Efficiency of Plant Glyco‐Engineering
Somanath Kallolimath, Clemens Gruber, H. Steinkellner, A. Castilho
2018Biotechnology Journal20 citations Open access
Semantic Scholar
Recombinant plant-derived human IgE glycoproteomics.
Laura Montero-Morales, Daniel Maresch, A. Castilho, Ayşegül Turupcu +7 more
2017Journal of Proteomics20 citations Open access
Semantic Scholar
The N-glycan on Asn54 affects the atypical N-glycan composition of plant-produced interleukin-22, but does not influence its activity.
Ruud H. P. Wilbers, Lotte B Westerhof, Lauri J Reuter, A. Castilho +7 more
2016Plant Biotechnology Journal18 citations Open access
Semantic Scholar
Analysis of a set of homoeologous group 1 wheat-Aegilops umbellulata recombinant chromosome lines using genetic markers
A. Castilho, T. E. Miller, J. Heslop-Harrison
1997Theoretical and Applied Genetics18 citations
Semantic Scholar
Reprogramming of rye rDNA in triticale during microsporogenesis
Manuela Silva, Á. Queiroz, N. Neves, A. Barão +3 more
1995Chromosome Research18 citations Open access
Semantic Scholar
influence of DNA methylation on rye B-chromosome nondisjunction
N. Neves, A. Barão, A. Castilho, M. D. da Silva +4 more
199218 citations
Semantic Scholar
Comparative analysis of plant transient expression vectors for targeted N-glycosylation
Lukas Eidenberger, Florian Eminger, A. Castilho, H. Steinkellner
2022Frontiers in Bioengineering and Biotechnology15 citations Open access
Semantic Scholar
N-Glyco-Engineering in Plants: Update on Strategies and Major Achievements.
H. Steinkellner, A. Castilho
2015Methods in molecular biology14 citations
Semantic Scholar
The developmental stage of inactivation of rye origin rRNA genes in the embryo and endosperm of wheat × rye F1 hybrids
A. Castilho, Á. Queiroz, N. Neves, A. Barão +2 more
1995Chromosome Research13 citations Open access
Semantic Scholar
The Instability of Dimeric Fc-Fusions Expressed in Plants Can Be Solved by Monomeric Fc Technology
Pia Gattinger, S. Izadi, C. Grünwald-Gruber, Somanath Kallolimath +1 more
2021Frontiers in Plant Science12 citations Open access
Semantic Scholar
In planta deglycosylation improves the SARS-CoV-2 neutralization activity of recombinant ACE2-Fc
S. Izadi, U. Vavra, Stanislav Melnik, C. Grünwald-Gruber +8 more
2023Frontiers in Bioengineering and Biotechnology10 citations Open access
Semantic Scholar
Assessment of transient expression strategies to sialylate recombinant proteins in N. benthamiana.
S. Izadi, Vinny Kunnummel, H. Steinkellner, Stefan Werner +1 more
2023Journal of Biotechnology9 citations Open access
Semantic Scholar
Transient Glyco-Engineering of N. benthamiana Aiming at the Synthesis of Multi-antennary Sialylated Proteins.
A. Loos, A. Castilho
2015Methods in molecular biology9 citations
Semantic Scholar
Engineered soluble, trimerized 4-1BBL variants as potent immunomodulatory agents
C. Battin, A. de Sousa Linhares, J. Leitner, Anna Grossmann +7 more
2023Cancer Immunology and Immunotherapy7 citations Open access
Semantic Scholar

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