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H. Chai · SciRah

Researcher profile · Semantic Scholar

H. Chai

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H. Chai — researcher profile on SciRah

h-index: 47
Works: 160
Citations: 7,201

Most-cited papers

Drug discovery from natural sources
Young-Won Chin, Marcy J. Balunas, H. Chai, A. Kinghorn
2006AAPS Journal737 citations Open access
Semantic Scholar
The Relevance of Higher Plants in Lead Compound Discovery Programs
A. Kinghorn, L. Pan, Joshua N. Fletcher, H. Chai
2011Journal of Natural Products270 citations Open access
Semantic Scholar
Lignans and other constituents of the fruits of Euterpe oleracea (Acai) with antioxidant and cytoprotective activities.
Young-Won Chin, H. Chai, W. Keller, A. Kinghorn
2008Journal of Agricultural and Food Chemistry178 citations
Semantic Scholar
The continuing search for antitumor agents from higher plants
L. Pan, H. Chai, A. Kinghorn
2010Phytochemistry Letters169 citations Open access
Semantic Scholar
Discovery of new anticancer agents from higher plants
L. Pan, H. Chai, A. Kinghorn
2012Frontiers in Bioscience128 citations Open access
Semantic Scholar
Xanthones with quinone reductase-inducing activity from the fruits of Garcinia mangostana (Mangosteen).
Young-Won Chin, H. Jung, H. Chai, William J. Keller +1 more
2008Phytochemistry127 citations
Semantic Scholar
Anthraquinones with quinone reductase-inducing activity and benzophenones from Morinda citrifolia (noni) roots.
Ye Deng, Young-Won Chin, H. Chai, William J. Keller +1 more
2007Journal of Natural Products117 citations
Semantic Scholar
Bioactive constituents of Helianthus tuberosus (Jerusalem artichoke)
L. Pan, Michelle R. Sinden, A. Kennedy, H. Chai +3 more
2009112 citations
Semantic Scholar
Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry)
H. Tomosaka, Young-Won Chin, A. Salim, William J. Keller +2 more
2008Phytotherapy Research108 citations
Semantic Scholar
Cytotoxic Xanthone Constituents of the Stem Bark of Garcinia mangostana (Mangosteen)
A. Han, Jeong-ah Kim, Daniel D. Lantvit, L. Kardono +6 more
2009Journal of Natural Products103 citations Open access
Semantic Scholar
Silvestrol, a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7.
Soyoung Kim, B. Hwang, Bao-Ning Su, H. Chai +4 more
2007Anticancer Research102 citations
Semantic Scholar
Bioactive Flavaglines and Other Constituents Isolated from Aglaia perviridis
L. Pan, Ulyana Muñoz Acuña, Jie Li, Nivedita Jena +7 more
2013Journal of Natural Products76 citations Open access
Semantic Scholar
Cytotoxic and NF-κB Inhibitory Constituents of the Stems of Cratoxylum cochinchinense and Their Semi-synthetic Analogues
Yulin Ren, S. Matthew, D. Lantvit, Ninh Ngoc Tràn +6 more
2011Journal of Natural Products75 citations Open access
Semantic Scholar
Potential anticancer activity of naturally occurring and semisynthetic derivatives of aculeatins A and B from Amomum aculeatum.
Young-Won Chin, A. Salim, Bao-Ning Su, Qiuwen Mi +7 more
2008Journal of Natural Products67 citations Open access
Semantic Scholar
Isolation and Characterization of Minor Analogues of Silvestrol and other Constituents from a Large-scale Recollection of Aglaia foveolata
L. Pan, L. Kardono, S. Riswan, H. Chai +6 more
2010Journal of Natural Products66 citations Open access
Semantic Scholar
Potent Cytotoxic Arylnaphthalene Lignan Lactones from Phyllanthus poilanei
Yulin Ren, D. Lantvit, You-Ping Deng, Ragu Kanagasabai +9 more
2014Journal of Natural Products59 citations Open access
Semantic Scholar
Bioactivity-guided isolation of cytotoxic constituents of Brucea javanica collected in Vietnam
L. Pan, Young-Won Chin, H. Chai, Ninh Ngoc Tràn +2 more
2008Bioorganic & Medicinal Chemistry58 citations Open access
Semantic Scholar
Cardiac Glycoside Constituents of Streblus asper with Potential Antineoplastic Activity
Yulin Ren, Wei-Lun Chen, D. Lantvit, E. Sass +10 more
2016Journal of Natural Products52 citations Open access
Semantic Scholar
Cytotoxic constituents from the fruiting branches of Callicarpa americana collected in southern Florida.
W. Jones, Tatiana Lobo-Echeverri, Qiuwen Mi, H. Chai +4 more
2007Journal of Natural Products52 citations Open access
Semantic Scholar
Alkaloids from Microcos paniculata with Cytotoxic and Nicotinic Receptor Antagonistic Activities
Patrick C. Still, B. Yi, Tatiana F. González-Cestari, L. Pan +7 more
2013Journal of Natural Products51 citations Open access
Semantic Scholar
Absolute Configuration of (−)-Gambogic Acid, an Antitumor Agent
Yulin Ren, C. Yuan, H. Chai, Yuanqing Ding +3 more
2010Journal of Natural Products50 citations Open access
Semantic Scholar
Bioassay-guided Isolation of Constituents of Piper sarmentosum Using a Mitochondrial Transmembrane Potential Assay
L. Pan, S. Matthew, D. Lantvit, Xiao-Li Zhang +6 more
2011Journal of Natural Products49 citations Open access
Semantic Scholar
Proteasome-inhibitory and cytotoxic constituents of Garcinia lateriflora: absolute configuration of caged xanthones
Yulin Ren, Daniel D. Lantvit, Esperanza J. Carcache de Blanco, L. Kardono +10 more
2010Tetrahedron49 citations Open access
Semantic Scholar
Discovery of anticancer agents of diverse natural origin
A. Kinghorn, Esperanza J. Carcache de Blanco, H. Chai, J. Orjala +14 more
2009Pure and applied chemistry. Chimie pure et appliquee49 citations Open access
Semantic Scholar
Bioactive 5,6-Dihydro-α-pyrone Derivatives from Hyptis brevipes
Ye Deng, Marcy J. Balunas, Jeong-ah Kim, D. Lantvit +9 more
2009Journal of Natural Products49 citations Open access
Semantic Scholar
Cytotoxic flavaglines and bisamides from Aglaia edulis.
Soyoung Kim, Young-Won Chin, Bao-Ning Su, S. Riswan +7 more
2006Journal of Natural Products49 citations Open access
Semantic Scholar
The classical drug discovery approach to defining bioactive constituents of botanicals.
A. Kinghorn, H. Chai, Chung K. I. Sung, William J. Keller
2011Fitoterapia48 citations
Semantic Scholar
Halogenated Compounds from Directed Fermentation of Penicillium concentricum, an Endophytic Fungus of the Liverwort Trichocolea tomentella.
Tehane Ali, M. Inagaki, H. Chai, T. Wieboldt +2 more
2017Journal of Natural Products43 citations Open access
Semantic Scholar
Antioxidant and quinone reductase-inducing constituents of black chokeberry (Aronia melanocarpa) fruits.
Jie Li, Ye Deng, C. Yuan, L. Pan +3 more
2012Journal of Agricultural and Food Chemistry43 citations
Semantic Scholar
Cytotoxic and NF-κB and mitochondrial transmembrane potential inhibitory pentacyclic triterpenoids from Syzygium corticosum and their semi-synthetic derivatives
Yulin Ren, G. Anaya-Eugenio, Austin A. Czarnecki, Ninh Ngoc Tràn +6 more
2018Bioorganic & Medicinal Chemistry42 citations Open access
Semantic Scholar
Constituents of the Leaves and Stem Bark of Aglaia foveolata.
A. Salim, H. Chai, Ismail Rachman, S. Riswan +4 more
2007Tetrahedron41 citations Open access
Semantic Scholar
Merocyclophanes A and B, Antiproliferative Cyclophanes from the Cultured Terrestrial Cyanobacterium Nostoc sp
Hahk-Soo Kang, B. Santarsiero, Hyunjung Kim, Aleksej Krunić +5 more
2012Phytochemistry40 citations Open access
Semantic Scholar
Ponapensin, a cyclopenta[bc]benzopyran with potent NF-kappaB inhibitory activity from Aglaia ponapensis.
A. Salim, A. Pawlus, H. Chai, N. Farnsworth +2 more
2007Bioorganic & Medicinal Chemistry Letters40 citations Open access
Semantic Scholar
Constituents of an Extract of Cryptocarya rubra Housed in a Repository with Cytotoxic and Glucose Transport Inhibitory Effects
Yulin Ren, C. Yuan, Yanrong Qian, H. Chai +3 more
2013Journal of Natural Products39 citations Open access
Semantic Scholar
Antileishmanial and Cytotoxic Activity of Some Highly Oxidized Abietane Diterpenoids from the Bald Cypress, Taxodium distichum
C. Naman, Anthony D. Gromovsky, Cory M. Vela, Joshua N. Fletcher +8 more
2016Journal of Natural Products38 citations Open access
Semantic Scholar
Bioactive indole alkaloids isolated from Alstonia angustifolia
L. Pan, César A. Terrazas, Ulyana Muñoz Acuña, Ninh Ngoc Tràn +5 more
2014Phytochemistry Letters38 citations Open access
Semantic Scholar
Cytotoxic and NF-κB inhibitory sesquiterpene lactones from Piptocoma rufescens
Yulin Ren, U. M. Acuña, Francisco Jiménez, Ricardo García +7 more
2012Tetrahedron37 citations Open access
Semantic Scholar
Isolation, Structure Elucidation, and Biological Evaluation of 16,23-Epoxycucurbitacin Constituents from Eleaocarpus chinensis
L. Pan, Yeonjoong Yong, Ye Deng, D. Lantvit +6 more
2012Journal of Natural Products35 citations Open access
Semantic Scholar
Cytotoxic and natural killer cell stimulatory constituents of Phyllanthus songboiensis
Yulin Ren, C. Yuan, You-Ping Deng, Ragu Kanagasabai +8 more
2015Phytochemistry34 citations Open access
Semantic Scholar
Cytotoxic constituents from the stem bark of Dichapetalum gelonioides collected in the Philippines.
Liqiong Fang, A. Ito, H. Chai, Qiuwen Mi +11 more
2006Journal of Natural Products34 citations Open access
Semantic Scholar
Bioactive Constituents of Indigofera spicata
L. Pérez, Jie Li, D. Lantvit, L. Pan +6 more
2013Journal of Natural Products31 citations Open access
Semantic Scholar
Cytotoxic and NF-κB Inhibitory Constituents of Artocarpus rigida
Yulin Ren, L. Kardono, S. Riswan, H. Chai +4 more
2010Journal of Natural Products30 citations Open access
Semantic Scholar
Pyrrole Alkaloids with Potential Cancer Chemopreventive Activity Isolated from a Goji Berry-Contaminated Commercial Sample of African Mango
Jie Li, L. Pan, C. Naman, Ye Deng +3 more
2014Journal of Agricultural and Food Chemistry29 citations Open access
Semantic Scholar
Antiproliferative Constituents of the Roots of Ethiopian Podocarpus falcatus and Structure Revision of 2α-Hydroxynagilactone F and Nagilactone I.
Ermias Mekuria Addo, H. Chai, Ariaya Hymete, M. Y. Yeshak +3 more
2015Journal of Natural Products28 citations
Semantic Scholar
Computer-Assisted Structure Elucidation of Black Chokeberry (Aronia melanocarpa) Fruit Juice Isolates with a New Fused Pentacyclic Flavonoid Skeleton
C. Naman, Jie Li, A. Moser, Jeffery M. Hendrycks +5 more
2015Organic Letters28 citations Open access
Semantic Scholar
Cytotoxic clerodane diterpenoids from the leaves of Premna tomentosa.
Young-Won Chin, William P. Jones, Qiuwen Mi, Ismail Rachman +8 more
2006Phytochemistry28 citations
Semantic Scholar
Phytochemical and Bioactivity Studies on Constituents of the Leaves of Vitex Quinata
Ye Deng, Young-Won Chin, H. Chai, E. C. D. de Blanco +5 more
2011Phytochemistry Letters27 citations Open access
Semantic Scholar
Northalrugosidine is a Bisbenzyltetrahydroisoquinoline Alkaloid from Thalictrum alpinum with in Vivo Antileishmanial Activity
C. Naman, G. Gupta, Sanjay Varikuti, H. Chai +3 more
2015Journal of Natural Products25 citations Open access
Semantic Scholar
Investigation of Vietnamese plants for potential anticancer agents
L. Pérez, Patrick C Still, C. Naman, Yulin Ren +8 more
2014Phytochemistry Reviews24 citations Open access
Semantic Scholar
Synthesis and antiproliferative activity of derivatives of the phyllanthusmin class of arylnaphthalene lignan lactones.
J. Woodard, Andrew C. Huntsman, Pratiq A. Patel, H. Chai +10 more
2018Bioorganic & Medicinal Chemistry23 citations Open access
Semantic Scholar

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A. Kinghorn×29
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A. Kinghorn — researcher profile on SciRah
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Ninh Ngoc Tràn×13
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A. Kinghorn×13
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Yulin Ren — researcher profile on SciRah

Young-Won Chin×11

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L. Kardono — researcher profile on SciRah

Esperanza J. Carcache de Blanco×10

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