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H. Hillen · SciRah

Researcher profile · Semantic Scholar

H. Hillen

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H. Hillen — researcher profile on SciRah

h-index: 22
Works: 65
Citations: 2,713

Most-cited papers

Globular amyloid β‐peptide1−42 oligomer − a homogenous and stable neuropathological protein in Alzheimer's disease
S. Barghorn, V. Nimmrich, Andreas Striebinger, Carsten Krantz +9 more
2005517 citations
Semantic Scholar
Structural characterization of a soluble amyloid beta-peptide oligomer.
Li-Ping Yu, R. Edalji, J. Harlan, T. Holzman +13 more
2009Biochemistry345 citations
Semantic Scholar
Amyloid β Oligomers (Aβ1–42 Globulomer) Suppress Spontaneous Synaptic Activity by Inhibition of P/Q-Type Calcium Currents
V. Nimmrich, C. Grimm, A. Draguhn, S. Barghorn +6 more
2008Journal of Neuroscience250 citations Open access
Semantic Scholar
Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease.
S. Barghorn, V. Nimmrich, Andreas Striebinger, Carsten Krantz +9 more
2005Journal of Neurochemistry224 citations
Semantic Scholar
Molecular characterization of human and bovine endothelin converting enzyme (ECE‐1)
M. Schmidt, B. Kröger, Elard Jacob, H. Seulberger +5 more
1994FEBS Letters194 citations
Semantic Scholar
Obesity is associated with tissue-specific activation of renal angiotensin-converting enzyme in vivo: evidence for a regulatory role of endothelin.
Matthias Barton, R. Carmona, H. Morawietz, L. d'Uscio +8 more
2000HYPERTENSION134 citations
Semantic Scholar
Abeta-globulomers are formed independently of the fibril pathway.
G. P. Gellermann, H. Byrnes, Andreas Striebinger, K. Ullrich +3 more
2008Neurobiology of Disease126 citations Open access
Semantic Scholar
Structure and molecular arrangement of proteolipid protein of central nervous system myelin.
W. Stoffel, H. Hillen, Helmut Giersiefen
1984Proceedings of the National Academy of Sciences of the United States of America125 citations Open access
Semantic Scholar
The primary structure of bovine brain myelin lipophilin (proteolipid apoprotein).
W. Stoffel, H. Hillen, Werner E. Schröder, R. Deutzmann
1983Hoppe-Seyler´s Zeitschrift für physiologische Chemie103 citations
Semantic Scholar
Generation and Therapeutic Efficacy of Highly Oligomer-Specific β-Amyloid Antibodies
H. Hillen, S. Barghorn, Andreas Striebinger, B. Labkovsky +11 more
2010Journal of Neuroscience101 citations Open access
Semantic Scholar
The Beta Amyloid Dysfunction (BAD) Hypothesis for Alzheimer’s Disease
H. Hillen
2019Frontiers in Neuroscience94 citations Open access
Semantic Scholar
Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism.
M. Budayova-Spano, W. Grabarse, N. Thielens, H. Hillen +5 more
2002Structure65 citations Open access
Semantic Scholar
Two‐dimensional analysis of myocardial protein expression following myocardial ischemia and reperfusion in rabbits
H. Schwertz, T. Längin, H. Platsch, J. Richert +7 more
2002Proteomics49 citations
Semantic Scholar
Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer’s disease mouse model
M. Dorostkar, S. Burgold, S. Filser, S. Barghorn +5 more
2014Brain : a journal of neurology40 citations Open access
Semantic Scholar
Renal function and renal disease in the elderly: Part I.
W. J. Mulder, H. Hillen
2001European journal of internal medicine36 citations
Semantic Scholar
Serine Protease Inhibitor Nafamostat Given Before Reperfusion Reduces Inflammatory Myocardial Injury by Complement and Neutrophil Inhibition
H. Schwertz, Justin M. Carter, M. Russ, Sebastian Schubert +6 more
2008Journal of Cardiovascular Pharmacology35 citations Open access
Semantic Scholar
Globular amyloid b-peptide 1 ) 42 oligomer ) a homogenous and stable neuropathological protein in Alzheimer ’ s disease
S. Barghorn, V. Nimmrich, Andreas Striebinger, Carsten Krantz +9 more
200531 citations
Semantic Scholar
Discovery and synthesis of (S)-3-[2-(3,4-dimethoxyphenyl)ethoxy]-2- (4,6-dimethylpyrimidin-2-yloxy)-3,3-diphenylpropionic acid (LU 302872), a novel orally active mixed ET(A)/ET(B) receptor antagonist.
Willi Amberg, S. Hergenroder, H. Hillen, R. Jansen +6 more
1999Journal of Medicinal Chemistry28 citations Open access
Semantic Scholar
Amino-acid sequence of human and bovine brain myelin proteolipid protein (lipophilin) is completely conserved.
W. Stoffel, Helmut Giersiefen, H. Hillen, Werner Schroeder +1 more
1985Biological Chemistry Hoppe-Seyler27 citations
Semantic Scholar
Magnetic Resonance Imaging Detection and Time Course of Cerebral Microhemorrhages during Passive Immunotherapy in Living Amyloid Precursor Protein Transgenic Mice
F. Luo, N. Rustay, T. Seifert, Beate Roesner +8 more
2010Journal of Pharmacology and Experimental Therapeutics26 citations
Semantic Scholar
Renal function and renal disease in the elderly: Part II.
W. J. Mulder, H. Hillen
2001European journal of internal medicine24 citations
Semantic Scholar
Proteome analysis of myocardial tissue following ischemia and reperfusion--effects of complement inhibition.
M. Buerke, H. Schwertz, T. Längin, U. Buerke +10 more
2006Biochimica et Biophysica Acta22 citations
Semantic Scholar
Analysis of the primary structure of the strongly hydrophobic brain myelin proteolipid apoprotein (lipophilin). Isolation and amino acid sequence determination of proteolytic fragments.
W. Stoffel, Werner E. Schröder, H. Hillen, R. Deutzmann
1982Hoppe-Seyler´s Zeitschrift für physiologische Chemie22 citations
Semantic Scholar
Primary structure of the C-terminal cyanogen bromide fragments II, III and IV from bovine brain proteolipid-apoprotein.
W. Stoffel, H. Hillen, Werner Schroeder, R. Deutzmann
1982Hoppe-Seyler´s Zeitschrift für physiologische Chemie16 citations
Semantic Scholar
Lipophilin (proteolipid apoprotein) of brain white matter. Purification and amino acid sequence studies of the four tryptophan fragments.
W. Stoffel, H. Hillen, Werner E. Schröder, R. Deutzmann
1982Hoppe-Seyler´s Zeitschrift für physiologische Chemie15 citations
Semantic Scholar
Studies on cortisol metabolism during haemodialysis in man
K. Deck, B. Fischer, H. Hillen
1979European Journal of Clinical Investigation14 citations
Semantic Scholar
Is Science the Only Driver in Species Selection? An Internal Study to Evaluate Compound Requirements in the Minipig Compared to the Dog in Preclinical Studies
K. Schaefer, S. Rensing, H. Hillen, J. Burkhardt +1 more
2016Toxicologic pathology (Print)11 citations
Semantic Scholar
Plasma clearance of cortisol as a function of plasma cortisol levels in normal and obese persons and in patients with uraemia or cirrhosis of the liver.
K. Deck, P. Baur, H. Hillen
1979Acta Endocrinologica10 citations
Semantic Scholar
Monoclonal antibodies against human endothelin-converting enzyme-1.
T. Subkowski, H. Hillen, B. Kröger, M. Schmidt
1998Journal of Immunoassay9 citations
Semantic Scholar
[Estimation of free cortisol in urine (author's transl)].
K. Deck, L. Eberlein, H. Vetter, H. Hillen
1976Deutsche Medizinische Wochenschrift7 citations
Semantic Scholar
Discovery and Synthesis of (S)‐3‐[2‐(3,4‐Dimethoxyphenyl)ethoxy] ‐2‐(4,6‐dimethylpyrimidin‐2‐yloxy)‐3,3‐diphenylpropionic Acid (LU 302872), a Novel Orally Active Mixed ETA/ETB Receptor Antagonist.
W. Amberg, Stefan Hergenroeder, H. Hillen, R. Jansen +6 more
19995 citations
Semantic Scholar
Editorial: Beta-Amyloid oligomer specific treatments for Alzheimer's disease
H. Hillen
2023Frontiers in Neuroscience3 citations Open access
Semantic Scholar
Crystallization of human tumour necrosis factor
N. Walker, S. Marcinowski, H. Hillen, W. Mächtle +2 more
19903 citations
Semantic Scholar
P4‐195: Restoration of home cage activity in Tg2576 mice by immunotherapy with the Ab‐oligomer selective antibody A‐887755
A. Relo, S. Barghorn, U. Ebert, H. Hillen +3 more
20112 citations Open access
Semantic Scholar
P3–440: Effects of Aβ1–42 globulomer on electrophysiological properties of rat hippocampal neurons
C. Bruehl, V. Nimmrich, S. Barghorn, A. Draguhn +5 more
20062 citations
Semantic Scholar
P1‐409: Knockdown of plasminogen activator inhibitor 1 gene reduces cerebral amyloid‐beta peptide burden in a mouse model of Alzheimer's disease
H. Hillen, S. Barghorn, Andreas Striebinger, Li-Ping Yu +7 more
20081 citations
Semantic Scholar
Shwachman syndrome: CT and MR diagnosis.
E. P. Bom, F. M. van der Sande, R. T. Tjon, A. Tham +1 more
1993Journal of computer assisted tomography1 citations
Semantic Scholar
P2‐304: MRI detection and time course of cerebral microhemorrhages during Aβ antibody treatment in living APP transgenic mice
F. Luo, T. Seifert, Beate Roesner, H. Hillen +3 more
20080 citations Open access
Semantic Scholar
P2‐321: A novel compound enhances α‐secretase processing of amyloid precursor protein
S. Barghorn, Andreas Striebinger, Simone Giaisi, B. Labkovsky +2 more
20080 citations Open access
Semantic Scholar
O3‐05–03: Therapeutic effects of passive immunization with an Aβ‐oligomer‐ specific antibody in APP transgenic mice
U. Ebert, I. van der Auwera, M. Nolte, A. Meyer +8 more
20080 citations
Semantic Scholar
P2‐352: Effects of anti‐Aβ oligomer treatment on synaptic density in young Tg2576 mice: A preclinical model for measuring Alzheimer's disease modification
Claudia Pérez-Cruz, Bodo Janson, M. Nolte, N. Rustay +3 more
20080 citations
Semantic Scholar
P2‐483: Biophysical characterization of soluble amyloid‐β peptide oligomers
E. Olejniczak, Li-Ping Yu, R. Edalji, J. Harlan +13 more
20080 citations Open access
Semantic Scholar
Scan method, process for purifying oligomers Abeta not diffusible, selective antibodies against Abeta such oligomers not diffusible and a process for making such antibodies
S. Barghorn, U. Ebert, H. Hillen, P. Keller +2 more
20060 citations
Semantic Scholar
Screening method, a method for purifying nichtdiffundierbarer-beta-oligomeric, selective antibodies against these non-diffusible a-beta-oligomers, and methods for producing these antibodies
H. Hillen, Andreas Striebinger, P. Keller, S. Barghorn +1 more
20060 citations
Semantic Scholar
Monoclonal antibodies to amyloid-beta protein, and uses thereof
B. Labkovsky, Andreas Striebinger, S. Barghorn, H. Hillen +2 more
20060 citations
Semantic Scholar
Selection method, process for the purification of beta-oligomers to non-diffusible selective antibodies against these oligomers to non-diffusible-beta and a process for making such antibodies.
S. Barghorn, U. Ebert, H. Hillen, P. Keller +1 more
20060 citations
Semantic Scholar
Oligomers beta- (1.42) Amyloid derivatives thereof and antibodies to these, methods for preparation thereof and use thereof
H. Hillen, Andreas Striebinger, Carsten Krantz, A. Moeller +1 more
20040 citations
Semantic Scholar
Amyloid-β (1-42) oligomers, processes for their preparation and their use
H. Hillen, Carsten Krantz, A. Moeller, Reinhold Müller +1 more
20030 citations
Semantic Scholar
Monomeric structure of the zymogen of complement protease C1r
M. Budayova-Spano, W. Grabarse, N. Thielens, H. Hillen +5 more
20030 citations
Semantic Scholar
Monomeric structure of the active catalytic domain of complement protease C1r
M. Budayova-Spano, W. Grabarse, N. Thielens, H. Hillen +5 more
20030 citations
Semantic Scholar

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Andreas Striebinger×12
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