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A. J. Callaghan · SciRah

Researcher profile · Semantic Scholar

A. J. Callaghan

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A. J. Callaghan — researcher profile on SciRah

h-index: 15
Works: 39
Citations: 1,311

Most-cited papers

Structure of Escherichia coli RNase E catalytic domain and implications for RNA turnover
A. J. Callaghan, M. Marcaida, J. Stead, Kenneth J. McDowall +2 more
2005Nature286 citations Open access
Semantic Scholar
Studies of the RNA degradosome-organizing domain of the Escherichia coli ribonuclease RNase E.
A. J. Callaghan, Jukka P Aurikko, Leopold L. Ilag, J. G. Grossmann +7 more
2004Journal of Molecular Biology166 citations Open access
Semantic Scholar
Crystal Structure of Escherichia coli Polynucleotide Phosphorylase Core Bound to RNase E, RNA and Manganese: Implications for Catalytic Mechanism and RNA Degradosome Assembly
S. Nurmohamed, B. Vaidialingam, A. J. Callaghan, B. Luisi
2009Journal of Molecular Biology125 citations Open access
Semantic Scholar
The Crystal Structure of the Escherichia coli RNase E Apoprotein and a Mechanism for RNA Degradation
Daniel J. Koslover, A. J. Callaghan, M. Marcaida, E. Garman +3 more
2008Structure79 citations Open access
Semantic Scholar
Quaternary structure and catalytic activity of the Escherichia coli ribonuclease E amino-terminal catalytic domain.
A. J. Callaghan, J. G. Grossmann, Yulia Redko, Leopold L. Ilag +5 more
2003Biochemistry75 citations
Semantic Scholar
The regulatory protein RraA modulates RNA-binding and helicase activities of the E. coli RNA degradosome.
M. Górna, Z. Pietras, Yi-Chun Tsai, A. J. Callaghan +3 more
2010RNA: A publication of the RNA Society71 citations Open access
Semantic Scholar
Recognition of the 70S ribosome and polysome by the RNA degradosome in Escherichia coli
Yi-Chun Tsai, D. Du, Lilianha Domínguez-Malfavón, Daniela Dimastrogiovanni +4 more
2012Nucleic Acids Research69 citations Open access
Semantic Scholar
Polynucleotide Phosphorylase Activity May Be Modulated by Metabolites in Escherichia coli
S. Nurmohamed, Helen A. Vincent, C. Titman, V. Chandran +5 more
2011Journal of Biological Chemistry64 citations Open access
Semantic Scholar
"Zn-link": a metal-sharing interface that organizes the quaternary structure and catalytic site of the endoribonuclease, RNase E.
A. J. Callaghan, Yulia Redko, L. Murphy, J. G. Grossmann +7 more
2005Biochemistry53 citations
Semantic Scholar
Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS
Charlotte A. Henderson, Helen A. Vincent, Alessandra Casamento, Carlanne M. Stone +6 more
2013RNA: A publication of the RNA Society43 citations Open access
Semantic Scholar
Global conformational changes control the reactivity of methane monooxygenase.
Stephen C. Gallagher, A. J. Callaghan, Jin-Kui Zhao, Howard Dalton +1 more
1999Biochemistry37 citations
Semantic Scholar
Characterization of Vibrio cholerae Hfq Provides Novel Insights into the Role of the Hfq C-Terminal Region
Helen A. Vincent, Charlotte A. Henderson, T. J. Ragan, A. Garza-Garcia +6 more
2012Journal of Molecular Biology36 citations Open access
Semantic Scholar
The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family
Louise Kime, Helen A. Vincent, Deena M. A. Gendoo, S. Jourdan +3 more
2015Scientific Reports33 citations Open access
Semantic Scholar
The low-resolution solution structure of Vibrio cholerae Hfq in complex with Qrr1 sRNA
Helen A. Vincent, Charlotte A. Henderson, Carlanne M. Stone, P. Cary +4 more
2012Nucleic Acids Research30 citations Open access
Semantic Scholar
Inhibition of homologous phosphorolytic ribonucleases by citrate may represent an evolutionarily conserved communicative link between RNA degradation and central metabolism
Carlanne M. Stone, Louise E. Butt, J. Bufton, D. C. Lourenço +5 more
2017Nucleic Acids Research22 citations Open access
Semantic Scholar
Characterization of MicA interactions suggests a potential novel means of gene regulation by small non-coding RNAs
Charlotte A. Henderson, Helen A. Vincent, Carlanne M. Stone, J. Phillips +3 more
2013Nucleic Acids Research15 citations Open access
Semantic Scholar
Residues near the N-terminus of protein B control autocatalytic proteolysis and the activity of soluble methane mono-oxygenase.
A. J. Callaghan, T. Smith, S. Slade, H. Dalton
2002European Journal of Biochemistry14 citations
Semantic Scholar
Identification and analysis of novel small molecule inhibitors of RNase E: Implications for antibacterial targeting and regulation of RNase E
C. Mardle, Layla R. Goddard, Bailei C. Spelman, H. Atkins +5 more
2020Biochemistry and Biophysics Reports12 citations Open access
Semantic Scholar
High-density functional-RNA arrays as a versatile platform for studying RNA-based interactions
J. Phillips, Louise E. Butt, Charlotte A. Henderson, Martin Devonshire +6 more
2018Nucleic Acids Research12 citations Open access
Semantic Scholar
An Improved Method for Surface Immobilisation of RNA: Application to Small Non-Coding RNA - mRNA Pairing
Helen A. Vincent, J. Phillips, Charlotte A. Henderson, A. Roberts +6 more
2013PLoS ONE12 citations Open access
Semantic Scholar
Complementing structural information of modular proteins with small angle neutron scattering and contrast variation
J. Grossmann, A. J. Callaghan, M. Marcaida, B. F. Luisi +2 more
2008European Biophysics Journal11 citations Open access
Semantic Scholar
Reprogramming Gene Expression by Targeting RNA-Based Interactions: A Novel Pipeline Utilizing RNA Array Technology.
Charlotte A. Henderson, Helen A. Vincent, A. J. Callaghan
2021ACS Synthetic Biology10 citations Open access
Semantic Scholar
A structural and biochemical comparison of Ribonuclease E homologues from pathogenic bacteria highlights species-specific properties
C. Mardle, T. Shakespeare, Louise E. Butt, Layla R. Goddard +4 more
2019Scientific Reports9 citations Open access
Semantic Scholar
Developing Biosensors for SARS-CoV-2 Wastewater-Based Epidemiology: A Systematic Review of Trends, Limitations and Future Perspectives
Christopher C. Azubuike, F. Couceiro, S. Robson, Maya Z. Piccinni +4 more
2022Sustainability6 citations Open access
Semantic Scholar
Application of mRNA Arrays for the Production of mCherry Reporter-Protein Arrays for Quantitative Gene Expression Analysis.
Masoud Norouzi, Andrew R. Pickford, Louise E. Butt, Helen A. Vincent +1 more
2019ACS Synthetic Biology6 citations Open access
Semantic Scholar
Generation of small molecule-binding RNA arrays and their application to fluorogen-binding RNA aptamers
Charlotte A. Henderson, Callum A Rail, Louise E. Butt, Helen A. Vincent +1 more
2019Methods6 citations Open access
Semantic Scholar
Identification of small RNAs associated with RNA chaperone Hfq reveals a new stress response regulator in Actinobacillus pleuropneumoniae
G. C. da Silva, C. C. Rossi, J. Rosa, N. M. Sanches +9 more
2022Frontiers in Microbiology4 citations Open access
Semantic Scholar
Identification of Novel Inhibitors of Escherichia coli DNA Ligase (LigA)
Arqam Alomari, Robert Gowland, Callum Southwood, Jake Barrow +7 more
2021Molecules4 citations Open access
Semantic Scholar
Structure of E. Coli Rnase E Catalytic Domain and Implications for RNA Processing and Turnover
A. J. Callaghan, M. J. Marcaida, J. Stead, Kenneth J. McDowall +2 more
20053 citations
Semantic Scholar
Erratum: The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family
Louise Kime, Helen A. Vincent, Deena M. A. Gendoo, S. Jourdan +3 more
2015Scientific Reports1 citations Open access
Semantic Scholar
Generation of Functional-RNA Arrays by In Vitro Transcription and In Situ RNA Capture for the Detection of RNA-RNA Interactions.
Helen A. Vincent, Charlotte A. Henderson, Daniela Lopes Cardoso, A. J. Callaghan
2023Methods in molecular biology0 citations
Semantic Scholar
An Investigation into the Potential of Targeting Escherichia coli rne mRNA with Locked Nucleic Acid (LNA) Gapmers as an Antibacterial Strategy
Layla R. Goddard, C. Mardle, Hassan Gneid, Ciara G. Ball +6 more
2021Molecules0 citations Open access
Semantic Scholar
Crystal Structure of E. coli RNase E possessing M1 RNA fragments - Catalytic Domain
Daniel J. Koslover, A. J. Callaghan, M. J. Marcaida, E. Garman +3 more
20080 citations
Semantic Scholar
Crystal Structure of E. coli RNase E Apoprotein - Catalytic Domain
Daniel J. Koslover, A. J. Callaghan, M. J. Marcaida, M. Martick +2 more
20080 citations
Semantic Scholar
Complementing structural information of modular proteins with small angle neutron scattering and contrast variation
J. Grossmann, A. J. Callaghan, M. J. Marcaida, B. F. Luisi +5 more
2008European Biophysics Journal0 citations Open access
Semantic Scholar
Catalytic domain of E. coli RNase E in complex with 13-mer RNA
M. J. Marcaida, A. J. Callaghan, W. Scott, B. Luisi
20050 citations
Semantic Scholar
Structure and function of RNase E and the RNA degradosome assembly
M. J. Marcaida, A. J. Callaghan, W. Scott, M. Symmons +4 more
20050 citations Open access
Semantic Scholar
Catalytic domain of E. coli RNase E
M. Marcaida, A. J. Callaghan, B. Luisi
20050 citations
Semantic Scholar
The regulatory protein and component interactions of soluble methane monooxygenase
A. J. Callaghan
20000 citations
Semantic Scholar

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