A. Loudon

Most-cited papers

Clocking in to immunity
C. Scheiermann, J. Gibbs, L. Ince, A. Loudon
2018Nature reviews. Immunology493 citations Open access
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An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action
J. Gibbs, L. Ince, L. Matthews, Jun-Jie Mei +12 more
2014Nature Medicine445 citations Open access
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Biological and clinical insights from genetics of insomnia symptoms
J. Lane, S. Jones, H. Dashti, A. Wood +55 more
2019Nature Genetics374 citations Open access
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Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits
J. Lane, Jing-Jing Liang, Irma Vlasac, S. Anderson +16 more
2016Nature Genetics330 citations Open access
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Medicine in the fourth dimension
Christopher R. Cederroth, U. Albrecht, J. Bass, Steven A. Brown +14 more
2019Cell Metabolism314 citations Open access
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The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis
Vanja Pekovic-Vaughan, J. Gibbs, H. Yoshitane, N. Yang +11 more
2014Genes & Development312 citations Open access
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Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank
J. Lane, Irma Vlasac, S. Anderson, S. Kyle +13 more
2016Nature Communications293 citations Open access
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Immunity Around the Clock
K. Man, A. Loudon, A. Chawla
2016Science281 citations Open access
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Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes
He-Ming Wang, J. Lane, S. Jones, H. Dashti +41 more
2019Nature Communications205 citations Open access
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A Gq-Ca2+ Axis Controls Circuit-Level Encoding of Circadian Time in the Suprachiasmatic Nucleus
Marco Brancaccio, E. Maywood, J. Chesham, A. Loudon +1 more
2013Neuron186 citations Open access
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Clocks for all seasons: unwinding the roles and mechanisms of circadian and interval timers in the hypothalamus and pituitary
S. Wood, A. Loudon
2014Journal of Endocrinology177 citations Open access
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Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation
M. Pariollaud, J. Gibbs, Thomas W. Hopwood, S. Brown +22 more
2018Journal of Clinical Investigation174 citations Open access
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Lithium Impacts on the Amplitude and Period of the Molecular Circadian Clockwork
Jian Li, Wei-Qun Lu, Stephen Beesley, A. Loudon +1 more
2012PLoS ONE169 citations Open access
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Misalignment with the external light environment drives metabolic and cardiac dysfunction
A. West, Laura Smith, D. Ray, A. Loudon +2 more
2017Nature Communications141 citations Open access
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Natural selection against a circadian clock gene mutation in mice
K. Spoelstra, M. Wikelski, S. Daan, A. Loudon +1 more
2015Proceedings of the National Academy of Sciences of the United States of America139 citations Open access
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The circadian clock and asthma
H. Durrington, S. Farrow, A. Loudon, D. Ray
2013Thorax133 citations Open access
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The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia
G. Kitchen, Peter S. Cunningham, T. Poolman, M. Iqbal +13 more
2020Proceedings of the National Academy of Sciences of the United States of America123 citations Open access
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Binary Switching of Calendar Cells in the Pituitary Defines the Phase of the Circannual Cycle in Mammals
S. Wood, H. Christian, K. Miedzinska, Ben R. C. Saer +8 more
2015Current Biology117 citations Open access
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Hypothalamic clocks and rhythms in feeding behaviour.
David A. Bechtold, A. Loudon
2013Trends in Neurosciences109 citations Open access
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The circadian clock regulates inflammatory arthritis
Laura E. Hand, Thomas W. Hopwood, Suzanna H. Dickson, A. Walker +4 more
2016The FASEB Journal99 citations Open access
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Night shift work is associated with an increased risk of asthma
R. Maidstone, J. Turner, C. Vetter, H. Dashti +10 more
2020Thorax89 citations Open access
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The circadian clock protein REVERBα inhibits pulmonary fibrosis development
Peter S. Cunningham, P. Meijer, Alicja Nazgiewicz, S. Anderson +20 more
2019Proceedings of the National Academy of Sciences of the United States of America87 citations Open access
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Circadian biology: a 2.5 billion year old clock.
A. Loudon
2012Current Biology85 citations Open access
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Circadian VIPergic Neurons of the Suprachiasmatic Nuclei Sculpt the Sleep-Wake Cycle
Ben H. Collins, Sara Pierre-Ferrer, C. Muheim, David Lukacsovich +13 more
2020Neuron84 citations Open access
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The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication
X. Zhuang, A. Magrì, M. Hill, Alvina G. Lai +21 more
2019Nature Communications84 citations Open access
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Optimized Chemical Probes for REV-ERBα
R. Trump, S. Bresciani, A. Cooper, James P. Tellam +12 more
2013Journal of Medicinal Chemistry84 citations Open access
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The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock
Thomas W. Hopwood, Sarah Hall, Nicola Begley, Ruth Forman +13 more
2018Scientific Reports73 citations Open access
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REVERBa couples the circadian clock to hepatic glucocorticoid action
G. Caratti, M. Iqbal, L. Hunter, Donghwan Kim +22 more
2018Journal of Clinical Investigation72 citations Open access
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Circadian clock mechanism driving mammalian photoperiodism
S. Wood, M. Hindle, Y. Mizoro, Y. Cheng +9 more
2020Nature Communications70 citations Open access
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The quail genome: insights into social behaviour, seasonal biology and infectious disease response
K. Morris, M. Hindle, S. Boitard, D. Burt +24 more
2020BMC Biology68 citations Open access
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The pars tuberalis: The site of the circannual clock in mammals?
S. Wood, A. Loudon
2017General and Comparative Endocrinology67 citations Open access
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Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation
C. Gurumurthy, Aidan R. O'Brien, R. Quadros, J. Adams +109 more
2019Genome Biology66 citations Open access
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Time of Day Affects Eosinophil Biomarkers in Asthma: Implications for Diagnosis and Treatment
H. Durrington, G. Gioan-Tavernier, R. Maidstone, K. Krakowiak +6 more
2018American Journal of Respiratory and Critical Care Medicine66 citations Open access
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Circadian rhythm of exhaled biomarkers in health and asthma
M. Wilkinson, R. Maidstone, A. Loudon, J. Blaikley +6 more
2019European Respiratory Journal62 citations Open access
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Csnk1e Is a Genetic Regulator of Sensitivity to Psychostimulants and Opioids
C. Bryant, C. Parker, Li-Li Zhou, Christopher Olker +7 more
2012Neuropsychopharmacology59 citations Open access
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Visualizing and Quantifying Intracellular Behavior and Abundance of the Core Circadian Clock Protein PERIOD2
Nicola J. Smyllie, Violetta Pilorz, James Boyd, Q. Meng +9 more
2016Current Biology56 citations Open access
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A Novel Mechanism Controlling Resetting Speed of the Circadian Clock to Environmental Stimuli
Violetta Pilorz, Peter S. Cunningham, A. Jackson, A. West +3 more
2014Current Biology52 citations Open access
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Nuclear receptor REVERBα is a state-dependent regulator of liver energy metabolism
A. L. Hunter, Charlotte E. Pelekanou, Antony D. Adamson, P. Downton +10 more
2020Proceedings of the National Academy of Sciences of the United States of America50 citations Open access
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Circadian asthma airway responses are gated by REV-ERBα
H. Durrington, K. Krakowiak, P. Meijer, Nicola Begley +8 more
2020European Respiratory Journal48 citations Open access
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Adipocyte NR1D1 dictates adipose tissue expansion during obesity
A. L. Hunter, Charlotte E. Pelekanou, Nicholas J. Barron, Rebecca C. Northeast +12 more
2021eLife47 citations Open access
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Immunologic Profiling of the Atlantic Salmon Gill by Single Nuclei Transcriptomics
A. West, Y. Mizoro, S. Wood, L. Ince +7 more
2021Frontiers in Immunology43 citations Open access
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Circadian variation in pulmonary inflammatory responses is independent of rhythmic glucocorticoid signaling in airway epithelial cells
L. Ince, Zhen-Guang Zhang, Stephen Beesley, Ryan M. Vonslow +6 more
2018The FASEB Journal42 citations Open access
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Timed daily exercise remodels circadian rhythms in mice
A. Hughes, R. Samuels, Beatriz Baño-Otálora, M. D. Belle +6 more
2021Communications Biology40 citations Open access
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Adiponectin Induces A20 Expression in Adipose Tissue To Confer Metabolic Benefit
Laura E. Hand, P. Usán, G. Cooper, Lan-Ce Y. Xu +8 more
2014Diabetes39 citations Open access
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Induction of the Metabolic Regulator Txnip in Fasting-Induced and Natural Torpor
Laura E. Hand, Ben R. C. Saer, S. Hui, H. Jinnah +3 more
2013Endocrinology37 citations Open access
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Rheumatoid arthritis reprograms circadian output pathways
T. Poolman, J. Gibbs, A. Walker, Suzanna H. Dickson +10 more
2019Arthritis Research & Therapy35 citations Open access
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Npas4 Is Activated by Melatonin, and Drives the Clock Gene Cry1 in the Ovine Pars Tuberalis
A. West, S. M. Dupré, Le Yu, I. R. Paton +5 more
2013Molecular Endocrinology33 citations Open access
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Cryptochrome proteins regulate the circadian intracellular behavior and localization of PER2 in mouse suprachiasmatic nucleus neurons
Nicola J. Smyllie, J. Bagnall, Alex A. Koch, Dhevahi Niranjan +6 more
2022Proceedings of the National Academy of Sciences of the United States of America30 citations Open access
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Incidence of primary graft dysfunction after lung transplantation is altered by timing of allograft implantation
Peter S. Cunningham, R. Maidstone, H. Durrington, R. Venkateswaran +7 more
2018Thorax30 citations Open access
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The circadian clock gene Csnk1e regulates rapid eye movement sleep amount, and nonrapid eye movement sleep architecture in mice.
Li-Li Zhou, C. Bryant, A. Loudon, A. Palmer +2 more
2014Sleep27 citations Open access
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