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Hu Zhou · SciRah

Researcher profile · Semantic Scholar

Hu Zhou

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Hu Zhou — researcher profile on SciRah

h-index: 54
Works: 260
Citations: 13K

Most-cited papers

7-Dehydrocholesterol dictates ferroptosis sensitivity
Yaxu Li, Qiao Ran, Qiuhui Duan, Jia-Li Jin +21 more
2024Nature353 citations Open access
Semantic Scholar
Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies.
Qian Liu, Jing Zhang, Chen-Chen Guo, Mengcheng Wang +26 more
2024Cell215 citations Open access
Semantic Scholar
Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1
Heng Xu, Hong-Fang Zhao, C. Ding, Defang Jiang +10 more
2023Signal Transduction and Targeted Therapy171 citations Open access
Semantic Scholar
Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology
S. Ji, Linhui Feng, Zile Fu, Gaohua Wu +30 more
2023Science Translational Medicine125 citations Open access
Semantic Scholar
Multimodule characterization of immune subgroups in intrahepatic cholangiocarcinoma reveals distinct therapeutic vulnerabilities
Jian Lin, Yu-Ting Dai, Chen Sang, Guohe Song +18 more
2022Journal for ImmunoTherapy of Cancer74 citations Open access
Semantic Scholar
Stromal architecture and fibroblast subpopulations with opposing effects on outcomes in hepatocellular carcinoma
Yifei Cheng, Xiao-Fang Chen, Lih Feng, Zhicheng Yang +33 more
2025Cell Discovery69 citations Open access
Semantic Scholar
Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer.
Jia-cheng Li, Ting Liu, Yuan-Li Song, Ming-Yu Wang +11 more
2022Journal of Medicinal Chemistry69 citations
Semantic Scholar
AM-DMF-SCP: Integrated Single-Cell Proteomics Analysis on an Active Matrix Digital Microfluidic Chip
Zhicheng Yang, K. Jin, Yi-Min Chen, Qian Liu +9 more
2024JACS Au49 citations Open access
Semantic Scholar
Branched-chain amino acid transaminase 1 confers EGFR-TKI resistance through epigenetic glycolytic activation
Tao Zhang, Zilu Pan, Jing Gao, Qingqing Wu +24 more
2024Signal Transduction and Targeted Therapy43 citations Open access
Semantic Scholar
Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma
Lin-Lin Zhou, Tao Zhang, Yun Xue, Chuan Yue +9 more
2023Nature Communications43 citations Open access
Semantic Scholar
Amplifying antigen-induced cellular responses with proximity labelling
Shuojun Li, Ying-Hui Men, Zi-Han Wang, Ying-Cheng Wu +13 more
2025Nature41 citations
Semantic Scholar
Proteomics of adjacent-to-tumor samples uncovers clinically relevant biological events in hepatocellular carcinoma
Hong-Wen Zhu, You-Pei Lin, Dayun Lu, Shisheng Wang +14 more
2023National Science Review39 citations Open access
Semantic Scholar
A pancreatic cancer organoid biobank links multi-omics signatures to therapeutic response and clinical evaluation of statin combination therapy.
Yunguang Li, Shi-Jie Tang, Huan Wang, Hong-Wen Zhu +18 more
2025Cell Stem Cell38 citations Open access
Semantic Scholar
Discovery of LL-K8-22: A Selective, Durable, and Small-Molecule Degrader of the CDK8-Cyclin C Complex.
Ming-Yu Wang, Rongkun Lin, Jia-cheng Li, Y. Suo +10 more
2023Journal of Medicinal Chemistry34 citations
Semantic Scholar
Proteogenomic characterization of non-functional pancreatic neuroendocrine tumors unravels clinically relevant subgroups.
S. Ji, Lihua Cao, Jing Gao, Yang Du +39 more
2025Cancer Cell31 citations Open access
Semantic Scholar
Discovery of a potent PROTAC degrader for RNA demethylase FTO as antileukemic therapy
Lu Liu, Yuanlai Qiu, Yu-Ying Suo, Siyao Tong +8 more
2024Acta Pharmaceutica Sinica B31 citations Open access
Semantic Scholar
A covalent compound selectively inhibits RNA demethylase ALKBH5 rather than FTO
Gan-Qiang Lai, Yali Li, He-Ping Zhu, Tao Zhang +3 more
2024RSC Chemical Biology30 citations Open access
Semantic Scholar
A proteogenomic analysis of cervical cancer reveals therapeutic and biological insights
Jing Yu, Xiuqi Gui, Yunhao Zou, Qian Liu +28 more
2024Nature Communications29 citations Open access
Semantic Scholar
Elevated Nuclear PHGDH Synergistically Functions with cMyc to Reshape the Immune Microenvironment of Liver Cancer
Hong-Wen Zhu, Hua Yu, Hu Zhou, Wencheng Zhu +1 more
2023Advancement of science29 citations Open access
Semantic Scholar
"Two Birds One Stone" Strategy for the Site-Specific Analysis of Core Fucosylation and O-GlcNAcylation.
Ya-Wen Luo, Yuqiu Wang, Yinping Tian, Hu Zhou +1 more
2023Journal of the American Chemical Society29 citations
Semantic Scholar
Enzymatic Degradation of Deoxynivalenol with the Engineered Detoxification Enzyme Fhb7
Jun Yang, K. Liang, Han Ke, Yuebin Zhang +7 more
2024JACS Au26 citations Open access
Semantic Scholar
Discovery of Covalent and Cell-Active ALKBH5 Inhibitors with Potent Antileukemia Effects In Vivo.
Hengbo Wu, Gan-Qiang Lai, Ruixiang Cheng, Hui Huang +7 more
2025Angewandte Chemie25 citations Open access
Semantic Scholar
Serum proteomic analysis reveals the cardioprotective effects of Shexiang Baoxin Pill and Suxiao Jiuxin Pill in a rat model of acute myocardial infarction.
Nixue Song, Dayun Lu, Gaosong Wu, Shisheng Wang +11 more
2022Journal of Ethnopharmacology25 citations
Semantic Scholar
A Sensitive and Reversible Labeling Strategy Enables Global Mapping of the Core-Fucosylated Glycoproteome on Cell Surfaces.
Liu-Qing Wen, Yinping Tian, Yuqiu Wang, Hong-Bo Yin +3 more
2022Angewandte Chemie24 citations
Semantic Scholar
ASB7 is a negative regulator of H3K9me3 homeostasis.
Li-Wen Zhou, Zhen-Xuan Chen, Ye-Zi Zou, Xia Zhang +16 more
2025Science23 citations
Semantic Scholar
The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility
Xin Wang, Di-Hang Lin, Yue Yan, Anhui Wang +22 more
2023Science China Life Sciences22 citations
Semantic Scholar
Single-cell sequencing reveals the heterogeneity of pancreatic neuroendocrine tumors under genomic instability and histological grading
Zeng Ye, Yan Zhou, Yuheng Hu, Qiang Li +15 more
2024iScience20 citations Open access
Semantic Scholar
Photoactivated SOPP3 enables APEX2-mediated proximity labeling with high spatio-temporal resolution in live cells
Dajun Qu, Yaxin Li, Qian Liu, Biao Cao +7 more
2024bioRxiv18 citations Open access
Semantic Scholar
Establishment of a pseudovirus neutralization assay based on SARS-CoV-2 S protein incorporated into lentiviral particles
Sheng Wang, Lizhen Liu, Can Wang, Zi-Qiang Wang +4 more
2022Biosafety and Health17 citations Open access
Semantic Scholar
Gentiopicroside ameliorates psoriasis-like skin lesions in mice via regulating the Keap1-Nrf2 pathway and inhibiting keratinocyte activation
Jing Ren, X. Chen, Hao-Yu Wang, Tao Yang +7 more
2025Acta Pharmacologica Sinica16 citations Open access
Semantic Scholar
A rapid imaging-based screen for induced-proximity degraders identifies a potent degrader of oncoprotein SKP2
Yan-Kai Chu, Shishuang Chen, Ming-Yang Yang, Yin Chen +38 more
2025Nature Biotechnology14 citations
Semantic Scholar
Precision Synthesis and Antiliver Fibrosis Activity of a Highly Branched Acidic 63-Mer Pectin Polysaccharide.
Chaoyu Hu, Fei He, Ruixue Wu, Wanqi Zhou +9 more
2025Journal of the American Chemical Society13 citations
Semantic Scholar
An antidepressant mechanism underlying the allosteric inhibition of GluN2D-incorporated NMDA receptors at GABAergic interneurons
Ji-Lin Zhang, Jinjin Duan, Wei Li, Xian Wang +16 more
2025Science Advances12 citations Open access
Semantic Scholar
A Reversible Chemoenzymatic Labeling Strategy for Profiling of Protein O-Glucosylation.
Shilin Zhang, Yinping Tian, Yuqiu Wang, Fangyu Wei +2 more
2025Angewandte Chemie11 citations
Semantic Scholar
Uncovering PROTAC Sensitivity and Efficacy by Multidimensional Proteome Profiling: A Case for STAT3.
Yu-Ying Suo, Daohai Du, Chao Chen, Hong-Wen Zhu +10 more
2024Journal of Medicinal Chemistry11 citations
Semantic Scholar
SEPepQuant enhances the detection of possible isoform regulations in shotgun proteomics
Yong-Chao Dou, Yuejia Liu, Xin-Pei Yi, Lindsey K. Olsen +4 more
2023Nature Communications11 citations Open access
Semantic Scholar
iTRAQ‐based quantitative proteomics reveals biomarkers/pathways in psoriasis that can predict the efficacy of methotrexate
K. Yan, Qian Meng, Han He, Hong-Wen Zhu +7 more
2022Journal of the European Academy of Dermatology and Venereology11 citations
Semantic Scholar
Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines.
Zhuo Xu, Hui Wang, Qian Meng, Yiluan Ding +4 more
2023Biochemical Pharmacology10 citations
Semantic Scholar
Integrative proteogenomic analysis provides molecular insights and clinical significance in gallbladder cancer.
Zile Fu, Yuanli Song, Fen Liu, L.-V. Chen +16 more
2026Cancer Cell9 citations
Semantic Scholar
Decoding Protein Glycosylation by an Integrative Mass Spectrometry-Based De Novo Sequencing Strategy
Jing Gao, Hongxu Chen, Hong-Rui Yin, Xin Chen +7 more
2024bioRxiv9 citations Open access
Semantic Scholar
Discovery of Potent and Selective G9a Degraders for the Treatment of Pancreatic Cancer.
Yunkai Shi, Qianqian Shen, Ruikai Long, Yiwen Mao +6 more
2024Journal of Medicinal Chemistry9 citations Open access
Semantic Scholar
Targeting the RT loop of Src SH3 in Platelets Prevents Thrombosis without Compromising Hemostasis
Jian-Hua Mao, K. Zhu, Zhangbiao Long, Huimin Zhang +16 more
2022Advancement of science9 citations Open access
Semantic Scholar
One-Step Labeling Strategy for the Profiling of Multiple Types of Protein Glycosylation.
Yinping Tian, Yuqiu Wang, Ying Zhang, Jing-Yi Guo +4 more
2025Analytical Chemistry8 citations
Semantic Scholar
A “One-Step” Strategy for the Global Characterization of Core-Fucosylated Glycoproteome
Yuqiu Wang, Rui Yuan, Bo Liang, Jing Zhang +5 more
2024JACS Au8 citations Open access
Semantic Scholar
DPPA5A suppresses the mutagenic TLS and MMEJ pathways by modulating the cryptic splicing of Rev1 and Polq in mouse embryonic stem cells
Fangjie Jiang, Lin Wang, Yuping Dong, Wen-Hui Nie +3 more
2023Proceedings of the National Academy of Sciences of the United States of America8 citations Open access
Semantic Scholar
The stability of FKBP9 maintained by BiP is crucial for glioma progression
Shi-Rong Li, Wangxiao Xia, Bin Sun, Wei-Yan Peng +9 more
2023Genes and Diseases8 citations Open access
Semantic Scholar
18F-FDG PET as an imaging biomarker for the response to FGFR-targeted therapy of cancer cells via FGFR-initiated mTOR/HK2 axis
Yu-Chen Jiang, Qinghe Zeng, Qinghui Jiang, Xia Peng +12 more
2022Theranostics8 citations Open access
Semantic Scholar
Alternative Strategies of Reducing MYC Expression for the Treatment of Cancers.
Huijuan Chen, Jing-Feng Song, Yi-Hang Wang, Zhi-Jin Peng +4 more
2026Journal of Medicinal Chemistry7 citations
Semantic Scholar
Intestinal TGR5-targeted carrier-drug conjugate improves glycemic control in mice and pigs.
Yaqi Zhang, Hui Huang, Yaying Wang, Xiang Li +12 more
2025Science Translational Medicine7 citations
Semantic Scholar
A hydrogen–deuterium exchange mass spectrometry-based protocol for protein–small molecule interaction analysis
Qian Meng, Yuanli Song, Chen Zhou, Han He +2 more
2023Biophysics Reports7 citations Open access
Semantic Scholar

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