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A. Mancini · SciRah

Researcher profile · Semantic Scholar

A. Mancini

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A. Mancini — researcher profile on SciRah

h-index: 8
Works: 19
Citations: 1,240

Most-cited papers

The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer
Robert J. A. Bell, H. Rube, Alex Kreig, A. Mancini +13 more
2015Science489 citations Open access
Semantic Scholar
Understanding TERT Promoter Mutations: a Common Path to Immortality
Robert J. A. Bell, H. Rube, Ana Xavier-Magalhães, B. Costa +3 more
2016Molecular Cancer Research266 citations Open access
Semantic Scholar
Antibody targeting of E3 ubiquitin ligases for receptor degradation
Hadir Marei, Wen-Ting K. Tsai, Y. Kee, Karen Ruiz +34 more
2022Nature213 citations Open access
Semantic Scholar
Disruption of the β1L isoform of GABP reverses glioblastoma replicative immortality in a TERT promoter mutation-dependent manner
A. Mancini, Ana Xavier-Magalhães, Wendy S. Woods, Kien-Thiet Nguyen +14 more
2018Cancer Cell113 citations Open access
Semantic Scholar
Mutant IDH1 expression drives TERT promoter reactivation as part of the cellular transformation process
S. Ohba, J. Mukherjee, Tor-Christian Johannessen, A. Mancini +13 more
2016Cancer Research56 citations Open access
Semantic Scholar
Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage
Alexandra M. Amen, Christof Fellmann, K. Soczek, S. Ren +7 more
2020Proceedings of the National Academy of Sciences of the United States of America44 citations Open access
Semantic Scholar
Ligand-activated EGFR/MAPK signaling but not PI3K, are key resistance mechanisms to EGFR-therapy in colorectal cancer
X. Qu, Habib Hamidi, Radia M. Johnson, Ethan S. Sokol +14 more
2025Nature Communications30 citations Open access
Semantic Scholar
Crypt density and recruited enhancers underlie intestinal tumour initiation
Liam T. Gaynor, Harshabad Singh, Guodong Tie, Krithika Badarinath +8 more
2025Nature21 citations Open access
Semantic Scholar
ORAOV1, CCND1, and MIR548K Are the Driver Oncogenes of the 11q13 Amplicon in Squamous Cell Carcinoma
Celine I. Mahieu, A. Mancini, E. Vikram, Vicente Planells-Palop +2 more
2023Molecular Cancer Research6 citations Open access
Semantic Scholar
Disruption of stem cell niche–confined R-spondin 3 expression leads to impaired hematopoiesis
A. Kurtova, Melanie Heinlein, S. Haas, Lars Velten +17 more
2022Blood Advances5 citations Open access
Semantic Scholar
Abstract B12: GABP selectively binds and activates the mutant TERT promoter across multiple cancer types
Robert J. A. Bell, H. Rube, Alex Kreig, A. Mancini +13 more
20152 citations
Semantic Scholar
Reducing risk for cell therapy manufacturing with a battle-tested electroporation platform
A. Mancini
2023Cell and Gene Therapy Insights0 citations
Semantic Scholar
Abstract 1474: Hippo-mediated control of the mutant TERT promoter via MYC and GABP
Nicholas O. Stevers, A. Mancini, J. Costello
2023Cancer Research0 citations
Semantic Scholar
480 The spectrum of oligogenic variants in the RAS pathway in a PHACE cohort
D. Siegel, E. Partan, O. Davies, S. Chamlin +13 more
2022Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
GENE-43. TARGETING GABPb1L INHIBITS IN VIVO GROWTH OF TERT PROMOTER MUTANT GLIOBLASTOMA
Alexandra M. Amen, Rachel J. Lew, S. Ren, Andrew M Mckinney +4 more
2019Neuro-Oncology0 citations Open access
Semantic Scholar
Regulation of replicative immortality by GABPβ1L in TERT promoter mutant glioblastoma
A. Mancini
20180 citations
Semantic Scholar
CSIG-38. REVERSAL OF GLIOBLASTOMA REPLICATIVE IMMORTALITY IN A TERT PROMOTER MUTATION-DEPENDENT MANNER
A. Mancini, Ana Xavier-Magalhães, Wendy S. Woods, Kien-Thiet Nguyen +7 more
20170 citations Open access
Semantic Scholar
CBIO-18. HAPLOINSUFFICIENCY OF THE REGULATOR OF THE MUTANT TERT PROMOTER REVERSES GLIOBLASTOMA REPLICATIVE IMMORTALITY
A. Mancini, Ana Xavier-Magalhães, Wendy S. Woods, J. Hayes +8 more
20160 citations Open access
Semantic Scholar
GENO-07A MECHANISM OF MUTANT TERT PROMOTER ACTIVATION SHARED ACROSS CANCER TYPES
Robert J. A. Bell, H. Rube, Alex Kreig, A. Mancini +13 more
20150 citations Open access
Semantic Scholar

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