Karyn B. Cahill

Most-cited papers

1. Identification of Amino Acid Residues Responsible for the Selectivity of Tadalafil Binding to Two Closely Related Phosphodiesterases, PDE5 and PDE6*

   Karyn B. Cahill, J. Quade, K. Carleton, R. H. Cote

   2012Journal of Biological Chemistry37 citations Open access

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2. Direct Allosteric Regulation between the GAF Domain and Catalytic Domain of Photoreceptor Phosphodiesterase PDE6*

   Xiujun Zhang, Karyn B. Cahill, A. Elfenbein, V. Arshavsky +1 more

   2008Journal of Biological Chemistry27 citations Open access

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3. The molecular architecture of photoreceptor phosphodiesterase 6 (PDE6) with activated G protein elucidates the mechanism of visual excitation

   M. J. Irwin, Richa Gupta, Xiong-Zhuo Gao, Karyn B. Cahill +2 more

   2019Journal of Biological Chemistry17 citations Open access

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4. Pharmacological and molecular dynamics analyses of differences in inhibitor binding to human and nematode PDE4: Implications for management of parasitic nematodes

   Kevin D. Schuster, Mohammadjavad Mohammadi, Karyn B. Cahill, Suzanne L. Matte +3 more

   2019PLoS ONE11 citations Open access

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5. PDE inhibitors as potential pesticides targeting parasitic nematodes

   Kevin D. Schuster, Karyn B. Cahill, K. Morris, W. Thomas +1 more

   20133 citations

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6. Phosphodiesterase 6C, cGMP-specific cone alpha'

   Karyn B. Cahill, R. H. Cote

   2011AfCS-Nature Molecule Pages3 citations Open access

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7. The effect of presenilin on β-amyloid in knock-in mice carrying the human amyloid precursor protein with Swedish and/or London mutation

   T. Wiebringhaus, D. Wirak, R. Altman, Karyn B. Cahill +4 more

   20003 citations

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8. Function and Regulation of Photoreceptor Phosphodiesterase (PDE6) in the Visual Signaling Pathway

   R. H. Cote, Karyn B. Cahill

   20101 citations

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9. Comparative Genomic Analysis and Discrimination of Functional Differences in the Phosphodiesterase-5 (PDE5) and Photoreceptor PDE (PDE6) Enzyme Families

   Karyn B. Cahill, J. Quade, R. H. Cote, K. Carleton

   20070 citations

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