I. Elkholi

Most-cited papers

1. Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

   H. Bagci, Neera Sriskandarajah, A. Robert, J. Boulais +9 more

   2019Nature Cell Biology166 citations

   Semantic Scholar

   Save

2. Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels

   Marie-Anne Goyette, I. Elkholi, Chloé Apcher, H. Kuasne +6 more

   2021Proceedings of the National Academy of Sciences of the United States of America60 citations Open access

   Semantic Scholar

   Save

3. AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple-negative breast cancer

   Marie-Anne Goyette, Rebecca Cusseddu, I. Elkholi, A. Abu-Thuraia +4 more

   2019OncoTarget41 citations Open access

   Semantic Scholar

   Save

4. Breast Cancer Metastatic Dormancy and Relapse: An Enigma of Microenvironment(s)

   I. Elkholi, Andréane Lalonde, Morag Park, J. Côté

   2022Cancer Research32 citations Open access

   Semantic Scholar

   Save

5. Tissue plasminogen activator-based clot busting: Controlled delivery approaches

   I. El-Sherbiny, I. Elkholi, M. Yacoub

   2014Global Cardiology Science & Practice32 citations Open access

   Semantic Scholar

   Save

6. Myoglobin: From physiological role to potential implications in cancer.

   I. Elkholi, Marwa E. Elsherbiny, Marwan Emara

   2022Biochimica et biophysica acta. Reviews on cancer28 citations

   Semantic Scholar

   Save

7. Evaluation of Anti-Cancer Potential of Capsaicin-Loaded TrimethylChitosan-Based Nanoparticles in HepG2 Hepatocarcinoma Cells

   I. Elkholi

   201423 citations Open access

   Semantic Scholar

   Save

8. Interphase microtubule disassembly is a signaling cue that drives cell rounding at mitotic entry

   Kévin Leguay, Barbara Decelle, I. Elkholi, M. Bouvier +2 more

   2021bioRxiv21 citations Open access

   Semantic Scholar

   Save

9. Shedding of cancer susceptibility candidate 4 by the convertases PC7/furin unravels a novel secretory protein implicated in cancer progression

   S. Duval, A. Abu-Thuraia, I. Elkholi, Rui Chen +5 more

   2020Cell Death and Disease17 citations Open access

   Semantic Scholar

   Save

10. Targeting the dependence on PIK3C3-mTORC1 signaling in dormancy-prone breast cancer cells blunts metastasis initiation

    I. Elkholi, A. Robert, C. Malouf, Josh Wu +13 more

    2025Cancer Research8 citations Open access

    Semantic Scholar

    Save

11. How can we integrate the biology of breast cancer cell dormancy into clinical practice?

    I. Elkholi, A. A. N. Rose, J. Aguirre-Ghiso, Jean-François Côté

    2024Cancer Cell8 citations Open access

    Semantic Scholar

    Save

12. MRN Complex and Cancer Risk: Old Bottles, New Wine

    I. Elkholi, W. Foulkes, B. Rivera

    2021Clinical Cancer Research8 citations Open access

    Semantic Scholar

    Save

13. Expression of Myoglobin in Normal and Cancer Brain Tissues: Correlation With Hypoxia Markers

    Marwa E. Elsherbiny, Mohammed Shaaban, R. El-Tohamy, I. Elkholi +4 more

    2021Frontiers in Oncology8 citations Open access

    Semantic Scholar

    Save

14. Investigating the causal role of MRE11A p.E506* in breast and ovarian cancer

    I. Elkholi, Massimo Di Iorio, S. Fahiminiya, S. L. Arcand +16 more

    2021Scientific Reports8 citations Open access

    Semantic Scholar

    Save

15. Myoglobin variants are expressed in human glioblastoma cells‑hypoxia effect?

    R. El-Tohamy, I. Elkholi, Marwa E. Elsherbiny, M. Magdy +3 more

    2020Oncology Report8 citations Open access

    Semantic Scholar

    Save

16. High Ki-67 expression is associated with increased risk of distant recurrence in Oncotype Dx low risk breast cancer.

    S. Labidi, N. Mulla, I. Elkholi, Mariana Pilon Capella +5 more

    2025Clinical Breast Cancer6 citations Open access

    Semantic Scholar

    Save

17. Author Correction: Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

    H. Bagci, Neera Sriskandarajah, A. Robert, J. Boulais +9 more

    2020Nature Cell Biology5 citations Open access

    Semantic Scholar

    Save

18. Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

    I. Elkholi, J. Boulais, M. Thibault, Hong-Duc Phan +6 more

    2023bioRxiv3 citations Open access

    Semantic Scholar

    Save

19. Binimetinib and encorafenib for the treatment of advanced solid tumors with non-V600E BRAF mutations: results from the Phase II BEAVER trial

    April A. N. Rose, J. Maxwell, Emmanuelle Rousselle, Chantel L Mukonoweshuro +25 more

    2026Nature Communications2 citations Open access

    Semantic Scholar

    Save

20. Concurrence of FGFR1 mutations modulates oncogenesis in glioneuronal tumors

    J. Boni, Míriam Fernández-González, HyeRim Han, C. Roca +15 more

    2025EMBO Journal2 citations

    Semantic Scholar

    Save

21. Exploring the efficacy and mechanism of action of combined pan-Raf and MEK inhibition in halting the growth of non-V600 BRAF mutated tumors.

    I. Elkholi, S. Fraser, M. Biondini, Emmanuelle Rousselle +7 more

    2025Journal of Clinical Oncology1 citations Open access

    Semantic Scholar

    Save

22. Germline predisposition and the pattern of breast cancer metastasis.

    I. Elkholi, W. Foulkes

    2026Cancer Research0 citations

    Semantic Scholar

    Save

23. Effectiveness of a Molecular Tumor Board in Making Personalized Treatment Recommendations for Patients with Advanced Cancer

    A. Rose, M. Basik, C. Ferrario, P. Fallah +14 more

    2026medRxiv0 citations Open access

    Semantic Scholar

    Save

24. Correction for Goyette et al., Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels

    Marie-Anne Goyette, I. Elkholi, Chloé Apcher, H. Kuasne +6 more

    2026Proceedings of the National Academy of Sciences of the United States of America0 citations Open access

    Semantic Scholar

    Save

25. Multiple FGFR1 mutations modulate tumorigenic mechanisms in glioneuronal tumors

    J. Boni, Míriam Fernández-González, HyeRim Han, C. Roca +15 more

    2025bioRxiv0 citations

    Semantic Scholar

    Save

26. Targeting the dependence on PIK3C3-mTORC1 signaling in dormancy-prone breast cancer cells blunts metastasis initiation

    I. Elkholi, A. Robert, C. Malouf, H. Kuasne +11 more

    2024bioRxiv0 citations Open access

    Semantic Scholar

    Save

27. CDK4/6 and SHP2 mediate BRAF/MEK inhibitor resistance in Class 2 and 3 BRAF mutant cancers

    A. Rose, J. Maxwell, E. Rousselle, M. Riaud +21 more

    2024medRxiv0 citations Open access

    Semantic Scholar

    Save

28. Molecule boosts cancer vaccine response

    I. Elkholi

    20200 citations

    Semantic Scholar

    Save

29. A novel delivery system for an anticancer standard

    I. Elkholi

    2020Nature Middle East0 citations

    Semantic Scholar

    Save

30. Getting down to the nitty gritty of RNA error removal

    I. Elkholi

    2019Nature Middle East0 citations

    Semantic Scholar

    Save

31. Mining marine microbe genomes for novel drugs

    I. Elkholi

    2019Nature Middle East0 citations

    Semantic Scholar

    Save

32. Unveiling novel immunodeficiency mutations

    I. Elkholi

    2018Nature Middle East0 citations

    Semantic Scholar

    Save

33. Tubistor: A novel biological transistor

    I. Elkholi

    2018Nature Middle East0 citations

    Semantic Scholar

    Save

34. Pinpointing a genetic defect linked to immunodeficiency

    I. Elkholi

    2018Nature Middle East0 citations

    Semantic Scholar

    Save

35. Novel molecular recipe to regenerate skin ulcers

    I. Elkholi

    2018Nature Middle East0 citations

    Semantic Scholar

    Save

36. New guidelines for identifying novel viruses

    I. Elkholi

    2018Nature Middle East0 citations

    Semantic Scholar

    Save

37. Peripheral inflammation implicated in Parkinson’s disease

    I. Elkholi

    20180 citations

    Semantic Scholar

    Save

38. New insights into the molecular mechanisms of leukaemia

    I. Elkholi

    20170 citations

    Semantic Scholar

    Save

39. New playmaker in breast cancer metastasis revealed

    I. Elkholi

    20170 citations

    Semantic Scholar

    Save

40. New therapeutic targets for an old drug

    I. Elkholi

    20160 citations

    Semantic Scholar

    Save

41. ‘Nano’ anticancer drug delivery

    I. Elkholi

    20160 citations

    Semantic Scholar

    Save

42. Shields for resistant cancer cells

    I. Elkholi

    20160 citations

    Semantic Scholar

    Save

43. Culprit found in antifungal drug resistance

    I. Elkholi

    20160 citations

    Semantic Scholar

    Save

44. Scrutinizing malignant tissues

    I. Elkholi

    20160 citations

    Semantic Scholar

    Save

45. Novel insights into the complexity of graft-versus-host disease

    I. Elkholi

    20160 citations

    Semantic Scholar

    Save

46. Rare type of brain cancer reversed

    I. Elkholi

    20150 citations

    Semantic Scholar

    Save