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J. Lachin · SciRah

Researcher profile · Semantic Scholar

J. Lachin

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J. Lachin — researcher profile on SciRah

h-index: 101
Works: 378
Citations: 88K

Most-cited papers

Empagliflozin and Clinical Outcomes in Patients With Type 2 Diabetes Mellitus, Established Cardiovascular Disease, and Chronic Kidney Disease
C. Wanner, J. Lachin, S. Inzucchi, D. Fitchett +6 more
2018Circulation386 citations Open access
Semantic Scholar
Change in albuminuria as a surrogate endpoint for progression of kidney disease: a meta-analysis of treatment effects in randomised clinical trials.
H. Heerspink, T. Greene, H. Tighiouart, R. Gansevoort +87 more
2019The Lancet Diabetes and Endocrinology321 citations Open access
Semantic Scholar
Risk Factors for Diabetic Peripheral Neuropathy and Cardiovascular Autonomic Neuropathy in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study
B. Braffett, R. Gubitosi-Klug, J. Albers, E. Feldman +6 more
2020Diabetes189 citations Open access
Semantic Scholar
Risk Factors for Retinopathy in Type 1 Diabetes: The DCCT/EDIC Study
D. Hainsworth, I. Bebu, L. Aiello, W. Sivitz +11 more
2019Diabetes Care171 citations Open access
Semantic Scholar
Glycemia Reduction in Type 2 Diabetes — Glycemic Outcomes
D. Nathan, J. Lachin, A. Balasubramanyam, H. Burch +11 more
2022New England Journal of Medicine144 citations Open access
Semantic Scholar
Understanding Metabolic Memory: The Prolonged Influence of Glycemia During the Diabetes Control and Complications Trial (DCCT) on Future Risks of Complications During the Study of the Epidemiology of Diabetes Interventions and Complications (EDIC)
J. Lachin, D. Nathan
2021Diabetes Care136 citations Open access
Semantic Scholar
Cognitive Performance Declines in Older Adults with Type 1 Diabetes: Results from 32 Years of Follow-up in the DCCT/EDIC Study
A. Jacobson, C. Ryan, B. Braffett, R. Gubitosi-Klug +8 more
2021The Lancet Diabetes and Endocrinology106 citations Open access
Semantic Scholar
Glycemia Reduction in Type 2 Diabetes — Microvascular and Cardiovascular Outcomes
D. Nathan, J. Lachin, I. Bebu, H. Burch +15 more
2022New England Journal of Medicine102 citations Open access
Semantic Scholar
Risk Factors for Kidney Disease in Type 1 Diabetes
B. Perkins, I. Bebu, I. D. de Boer, M. Molitch +9 more
2019Diabetes Care99 citations Open access
Semantic Scholar
DNA methylation mediates HbA1c-associated complications development in Type 1 diabetes
Zhuo Chen, F. Miao, B. Braffett, J. Lachin +10 more
2020Nature Metabolism88 citations Open access
Semantic Scholar
Risk Factors for First and Subsequent CVD Events in Type 1 Diabetes: The DCCT/EDIC Study
I. Bebu, D. Schade, B. Braffett, M. Kosiborod +7 more
2020Diabetes Care79 citations Open access
Semantic Scholar
Residual β cell function in long-term type 1 diabetes associates with reduced incidence of hypoglycemia.
R. Gubitosi-Klug, B. Braffett, S. Hitt, V. Arends +10 more
2021Journal of Clinical Investigation71 citations Open access
Semantic Scholar
The Association of Coronary Artery Calcification (CAC) With Subsequent Incidence of Cardiovascular Disease (CVD) in DCCT/EDIC
M. Budoff, Jye-Yu Backlund, D. Bluemke, J. Polak +5 more
2019JACC Cardiovascular Imaging70 citations Open access
Semantic Scholar
Increased Risk of Severe Hypoglycemic Events Before and After Cardiovascular Outcomes in TECOS Suggests an At-Risk Type 2 Diabetes Frail Patient Phenotype
E. Standl, Susanna R. Stevens, P. Armstrong, J. Buse +8 more
2018Diabetes Care69 citations Open access
Semantic Scholar
The Beneficial Effects of Earlier Versus Later Implementation of Intensive Therapy in Type 1 Diabetes
J. Lachin, I. Bebu, D. Nathan
2021Diabetes Care49 citations Open access
Semantic Scholar
Mediation of the Effect of Glycemia on the Risk of CVD Outcomes in Type 1 Diabetes: The DCCT/EDIC Study
I. Bebu, B. Braffett, T. Orchard, Gayle M. Lorenzi +1 more
2019Diabetes Care45 citations Open access
Semantic Scholar
Hearing Impairment and Type 1 Diabetes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Cohort
D. Schade, Gayle M. Lorenzi, B. Braffett, Xiao-Yu Gao +10 more
2018Diabetes Care44 citations Open access
Semantic Scholar
Association of Insulin Dose, Cardiometabolic Risk Factors, and Cardiovascular Disease in Type 1 Diabetes During 30 Years of Follow-up in the DCCT/EDIC Study
B. Braffett, S. Dagogo-Jack, I. Bebu, W. Sivitz +3 more
2019Diabetes Care43 citations Open access
Semantic Scholar
Utility of using electrocardiogram measures of heart rate variability as a measure of cardiovascular autonomic neuropathy in type 1 diabetes patients
R. Pop-Busui, Jye-Yu Backlund, I. Bebu, B. Braffett +4 more
2021Journal of Diabetes Investigation40 citations Open access
Semantic Scholar
Early Glomerular Hyperfiltration and Long-Term Kidney Outcomes in Type 1 Diabetes: The DCCT/EDIC Experience.
M. Molitch, Xiao-Yu Gao, I. Bebu, I. D. de Boer +6 more
2019American Society of Nephrology. Clinical Journal40 citations Open access
Semantic Scholar
What are the Clinical, Quality-of-Life, and Cost Consequences of 30 Years of Excellent vs. Poor Glycemic Control in Type 1 Diabetes?
W. Herman, B. Braffett, S. Kuo, Joyce M. Lee +4 more
2018Journal of diabetes and its complications40 citations Open access
Semantic Scholar
Cardiometabolic Risk Factors and Incident Cardiovascular Disease Events in Women vs Men With Type 1 Diabetes
B. Braffett, I. Bebu, L. El ghormli, C. Cowie +7 more
2022JAMA Network Open37 citations Open access
Semantic Scholar
Cardiovascular Mortality Reduction With Empagliflozin in Patients With Type 2 Diabetes and Cardiovascular Disease.
D. Fitchett, S. Inzucchi, J. Lachin, C. Wanner +7 more
2018Journal of the American College of Cardiology37 citations Open access
Semantic Scholar
Associations of Microvascular Complications With the Risk of Cardiovascular Disease in Type 1 Diabetes
R. Gubitosi-Klug, Xiao-Yu Gao, R. Pop-Busui, I. D. de Boer +9 more
2021Diabetes Care35 citations Open access
Semantic Scholar
Evidence for C-peptide as a Validated Surrogate to Predict Clinical Benefits in Trials of Disease-Modifying Therapies for Type 1 Diabetes.
E. Latres, C. Greenbaum, Maria L Oyaski, C. Dayan +8 more
2024Diabetes33 citations
Semantic Scholar
Long-Term Benefit of Empagliflozin on Life Expectancy in Patients With Type 2 Diabetes Mellitus and Established Cardiovascular Disease.
B. Claggett, J. Lachin, S. Hantel, D. Fitchett +4 more
2018Circulation33 citations
Semantic Scholar
Continuous Glucose Monitoring in Adults With Type 1 Diabetes With 35 Years Duration From the DCCT/EDIC Study.
R. Gubitosi-Klug, B. Braffett, I. Bebu, Mary L. Johnson +9 more
2022Diabetes Care31 citations Open access
Semantic Scholar
Plasma advanced glycation end products and the subsequent risk of microvascular complications in type 1 diabetes in the DCCT/EDIC
V. Monnier, D. R. Sell, Xiao-Yu Gao, S. Genuth +2 more
2022BMJ Open Diabetes Research & Care31 citations Open access
Semantic Scholar
Risk factors for lower bone mineral density in older adults with type 1 diabetes: a cross-sectional study.
A. Schwartz, Jye-Yu Backlund, I. D. de Boer, M. Rubin +9 more
2022The Lancet Diabetes and Endocrinology30 citations Open access
Semantic Scholar
Nonparametric Statistical Analysis.
J. Lachin
2020Journal of the American Medical Association (JAMA)30 citations
Semantic Scholar
Brain Structure Among Middle-aged and Older Adults With Long-standing Type 1 Diabetes in the DCCT/EDIC Study.
A. Jacobson, B. Braffett, G. Erus, C. Ryan +11 more
2022Diabetes Care28 citations Open access
Semantic Scholar
Shape of the OGTT glucose response curve: relationship with β-cell function and differences by sex, race, and BMI in adults with early type 2 diabetes treated with metformin
K. Utzschneider, N. Younes, N. Rasouli, J. Barzilay +9 more
2021BMJ Open Diabetes Research & Care26 citations Open access
Semantic Scholar
An Observational Study of the Equivalence of Age and Duration of Diabetes to Glycemic Control Relative to the Risk of Complications in the Combined Cohorts of the DCCT/EDIC Study
I. Bebu, B. Braffett, D. Schade, W. Sivitz +8 more
2020Diabetes Care25 citations Open access
Semantic Scholar
Mediation of the association of smoking and microvascular complications by glycemic control in type 1 diabetes
B. Braffett, M. Rice, H. Young, J. Lachin
2019PLoS ONE23 citations Open access
Semantic Scholar
Screening eye exams in youth with type 1 diabetes under 18 years of age: once may be enough?
R. Gubitosi-Klug, I. Bebu, N. White, J. Malone +6 more
2019Pediatric Diabetes23 citations Open access
Semantic Scholar
Biochemical Markers of Bone Turnover in Older Adults with Type 1 Diabetes.
M. Rubin, I. D. de Boer, Jye-Yu Backlund, V. Arends +8 more
2022Journal of Clinical Endocrinology and Metabolism22 citations Open access
Semantic Scholar
Relationships Between the Cumulative Incidences of Long-term Complications in Type 1 Diabetes: the DCCT/EDIC Study.
I. Bebu, B. Braffett, I. D. de Boer, L. Aiello +7 more
2022Diabetes Care21 citations Open access
Semantic Scholar
Comparison of central laboratory HbA1c measurements obtained from a capillary collection versus a standard venous whole blood collection in the GRADE and EDIC studies
D. Nathan, H. Krause-Steinrauf, B. Braffett, V. Arends +8 more
2021PLoS ONE17 citations Open access
Semantic Scholar
Association of Baseline Characteristics With Insulin Sensitivity and β-Cell Function in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study Cohort
N. Rasouli, N. Younes, K. Utzschneider, S. Inzucchi +10 more
2020Diabetes Care17 citations Open access
Semantic Scholar
Neuropathic Pain With and Without Diabetic Peripheral Neuropathy in Type 1 Diabetes.
B. Braffett, L. El ghormli, James W. Albers, E. Feldman +8 more
2024Diabetes Care16 citations Open access
Semantic Scholar
Association of Estimated Time-in-Range Capillary Glucose Levels Versus HbA1c With Progression of Microvascular Complications in the Diabetes Control and Complications Trial.
J. Lachin, I. Bebu, Xiao-Yu Gao, D. Nathan +1 more
2022Diabetes Care16 citations Open access
Semantic Scholar
Coronary Artery Disease Events and Carotid Intima‐Media Thickness in Type 1 Diabetes in the DCCT/EDIC Cohort
J. Polak, Jye-Yu Backlund, M. Budoff, P. Raskin +2 more
2021Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease16 citations Open access
Semantic Scholar
Moderation of the Effect of Glycemia on the Risk of Cardiovascular Disease in Type 1 Diabetes: the DCCT/EDIC Study
I. Bebu, B. Braffett, T. Orchard, Gayle M. Lorenzi +3 more
2020Diabetes Research and Clinical Practice16 citations Open access
Semantic Scholar
Diabetes Care Editors’ Expert Forum 2018: Managing Big Data for Diabetes Research and Care
M. Riddle, L. Blonde, H. Gerstein, E. Gregg +5 more
2019Diabetes Care15 citations
Semantic Scholar
Optimal screening schedules for disease progression with application to diabetic retinopathy.
I. Bebu, J. Lachin
2018Biostatistics15 citations Open access
Semantic Scholar
Immune Complexes and the Risk of CVD in Type 1 Diabetes
M. Lopes-Virella, I. Bebu, Kelly J. Hunt, G. Virella +4 more
2019Diabetes13 citations Open access
Semantic Scholar
The 30-Year Cost-Effectiveness of Alternative Strategies to Achieve Excellent Glycemic Control in Type 1 Diabetes: An Economic Simulation Informed by the Results of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC)
W. Herman, B. Braffett, S. Kuo, Joyce M. Lee +4 more
2018Journal of diabetes and its complications12 citations Open access
Semantic Scholar
Association of Baseline Factors With Glycemic Outcomes in GRADE: A Comparative Effectiveness Randomized Clinical Trial.
W. T. Garvey, Robert M. Cohen, N. Butera, E. Kazemi +10 more
2024Diabetes Care11 citations Open access
Semantic Scholar
Relationship Between Average Glucose Levels and HbA1c Differs Across Racial Groups: A Substudy of the GRADE Randomized Trial.
David M. Nathan, William H. Herman, M. Larkin, H. Krause-Steinrauf +11 more
2024Diabetes Care11 citations
Semantic Scholar
Diabetes Risk Factors and Bone Microarchitecture as Assessed by High-Resolution Peripheral Quantitative Computed Tomography in Adults With Long-Standing Type 1 Diabetes.
Naina Sinha Gregory, A. Burghardt, Jye-Yu Backlund, M. Rubin +10 more
2023Diabetes Care11 citations Open access
Semantic Scholar

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