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Peggy Geluykens · SciRah

Researcher profile · Semantic Scholar

Peggy Geluykens

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Peggy Geluykens — researcher profile on SciRah

h-index: 8
Works: 14
Citations: 781

Most-cited papers

Resistance Mutations in Human Immunodeficiency Virus Type 1 Integrase Selected with Elvitegravir Confer Reduced Susceptibility to a Wide Range of Integrase Inhibitors
Olivia Goethals, R. Clayton, Marcia Van Ginderen, Inge Vereycken +12 more
2008Journal of Virology181 citations Open access
Semantic Scholar
A pan-serotype dengue virus inhibitor targeting the NS3–NS4B interaction
S. Kaptein, Olivia Goethals, Dominik Kiemel, A. Marchand +20 more
2021Nature179 citations Open access
Semantic Scholar
Blocking NS3–NS4B interaction inhibits dengue virus in non-human primates
Olivia Goethals, S. Kaptein, B. Kesteleyn, Jean-François Bonfanti +40 more
2023Nature118 citations Open access
Semantic Scholar
Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein
D. Roymans, H. D. De Bondt, E. Arnoult, Peggy Geluykens +10 more
2009Proceedings of the National Academy of Sciences of the United States of America92 citations Open access
Semantic Scholar
Primary mutations selected in vitro with raltegravir confer large fold changes in susceptibility to first-generation integrase inhibitors, but minor fold changes to inhibitors with second-generation resistance profiles.
Olivia Goethals, A. Vos, Marcia Van Ginderen, Peggy Geluykens +4 more
2010Virology64 citations Open access
Semantic Scholar
Which Compound to Select in Lead Optimization? Prospectively Validated Proteochemometric Models Guide Preclinical Development
G. V. van Westen, J. Wegner, Peggy Geluykens, Leen Kwanten +5 more
2011PLoS ONE54 citations Open access
Semantic Scholar
Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation
Dominik Kiemel, A. Kroell, S. Denolly, U. Haselmann +11 more
2024Nature Communications48 citations Open access
Semantic Scholar
Characterization of a dengue NS4B inhibitor originating from an HCV small molecule library
Ilane Hernández-Morales, Peggy Geluykens, M. Clynhens, Rudy Strijbos +16 more
2017Antiviral Research21 citations
Semantic Scholar
Modelling the impact of JNJ-1802, a first-in-class dengue inhibitor blocking the NS3-NS4B interaction, on in-vitro DENV-2 dynamics
C. McCormack, Olivia Goethals, N. Goeyvaerts, Xavier D. Woot de Trixhe +5 more
2023PLoS Comput. Biol.7 citations Open access
Semantic Scholar
From Oxetane to Thietane: Extending the Antiviral Spectrum of 2'-Spirocyclic Uridines by Substituting Oxygen with Sulfur.
Sandrine Grosse, A. Tahri, P. Raboisson, Yannis Houpis +8 more
2022ACS Medicinal Chemistry Letters6 citations Open access
Semantic Scholar
An Automated Time-of-Drug-Addition Assay to Routinely Determine the Mode of Action of HIV-1 Inhibitors
M. Van Loock, C. van den Eynde, J. Hansen, Peggy Geluykens +6 more
2013Assay and drug development technologies6 citations
Semantic Scholar
Publisher Correction: A pan-serotype dengue virus inhibitor targeting the NS3–NS4B interaction
S. Kaptein, Olivia Goethals, Dominik Kiemel, A. Marchand +20 more
2021Nature5 citations Open access
Semantic Scholar
A fluorescence-based high-throughput screening assay to identify HIV-1 inhibitors.
Peggy Geluykens, K. van Acker, J. Vingerhoets, C. van den Eynde +2 more
2013Methods in molecular biology3 citations
Semantic Scholar
An orthoflavivirus inhibitor targeting multifunctional NS2A protein, a previously unidentified target
Doortje Borrenberghs, K. Chan, S. V. Van Brandt, Steffen Jaensch +16 more
2026PLoS Pathogens0 citations Open access
Semantic Scholar

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