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J. Aiyar · SciRah

Researcher profile · Semantic Scholar

J. Aiyar

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J. Aiyar — researcher profile on SciRah

h-index: 19
Works: 32
Citations: 3,223

Most-cited papers

Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
S. Grissmer, A. Nguyen, J. Aiyar, D. C. Hanson +5 more
1994Molecular Pharmacology831 citations
Semantic Scholar
Calmodulin Mediates Calcium-dependent Activation of the Intermediate Conductance KCa Channel,IKCa1 *
Christopher M. Fanger, S. Ghanshani, N. Logsdon, H. Rauer +6 more
1999Journal of Biological Chemistry346 citations Open access
Semantic Scholar
A Novel Gene, hKCa4, Encodes the Calcium-activated Potassium Channel in Human T Lymphocytes*
N. Logsdon, Jiesheng Kang, J. Togo, E. P. Christian +1 more
1997Journal of Biological Chemistry311 citations Open access
Semantic Scholar
Compendium of voltage - gated ion channels: potassium channels
Gutman Ga, K. Chandy, J. Adelman, J. Aiyar +16 more
2003289 citations
Semantic Scholar
Topology of the pore-region of a K+ channel revealed by the NMR-derived structures of scorpion toxins.
J. Aiyar, J. Withka, J. Rizzi, D. H. Singleton +10 more
1995Neuron254 citations Open access
Semantic Scholar
International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels.
George A. Gutman, K. Chandy, John P. Adelman, J. Aiyar +30 more
2003Pharmacological Reviews164 citations
Semantic Scholar
Ric-3 Promotes Functional Expression of the Nicotinic Acetylcholine Receptor α7 Subunit in Mammalian Cells*
Mark E. Williams, B. Burton, A. Urrutia, A. Shcherbatko +3 more
2005Journal of Biological Chemistry157 citations Open access
Semantic Scholar
The Signature Sequence of Voltage-gated Potassium Channels Projects into the External Vestibule*
J. Aiyar, J. Rizzi, George A. Gutman, K. Chandy
1996Journal of Biological Chemistry128 citations Open access
Semantic Scholar
Structure-guided Transformation of Charybdotoxin Yields an Analog That Selectively Targets Ca2+-activated over Voltage-gated K+ Channels*
H. Rauer, Mark D. Lanigan, M. Pennington, J. Aiyar +4 more
2000Journal of Biological Chemistry107 citations Open access
Semantic Scholar
Novel nonpeptide agents potently block the C-type inactivated conformation of Kv1.3 and suppress T cell activation.
A. Nguyen, J. Kath, D. C. Hanson, M. S. Biggers +11 more
1996Molecular Pharmacology106 citations
Semantic Scholar
Differential Expression of KCNQ2 Splice Variants: Implications to M Current Function during Neuronal Development
Jeffrey S. Smith, Claudia A. Iannotti, P. Dargis, E. P. Christian +1 more
2001Journal of Neuroscience75 citations Open access
Semantic Scholar
Comparison of the Antinociceptive Profiles of Gabapentin and 3-Methylgabapentin in Rat Models of Acute and Persistent Pain: Implications for Mechanism of Action
Mark O. Urban, Kun-Kun Ren, Kenneth T. Park, Brian T. Campbell +6 more
2005Journal of Pharmacology and Experimental Therapeutics72 citations
Semantic Scholar
Purification, Visualization, and Biophysical Characterization of Kv1.3 Tetramers*
R. Spencer, Y. Sokolov, Huilin Li, Bruce Takenaka +8 more
1997Journal of Biological Chemistry62 citations Open access
Semantic Scholar
Pharmacological characterization of five cloned voltage - gated K channels
S. Grissmer, A. Nguyen, J. Aiyar, D. Hanson +5 more
199455 citations
Semantic Scholar
Regulation of mammalian Shaker‐related K+ channels: evidence for non‐conducting closed and non‐conducting inactivated states
H. Jäger, H. Rauer, A. Nguyen, J. Aiyar +2 more
1998Journal of Physiology54 citations Open access
Semantic Scholar
Identification and synthesis of [1,2,4]triazolo[3,4-a]phthalazine derivatives as high-affinity ligands to the α2δ-1 subunit of voltage gated calcium channel
A. Lebsack, J. Gunzner, Bowei Wang, Richard Pracitto +7 more
200442 citations Open access
Semantic Scholar
Genomic organization, nucleotide sequence, biophysical properties, and localization of the voltage-gated K+ channel gene KCNA4/Kv1.4 to mouse chromosome 2/human 11p14 and mapping of KCNC1/Kv3.1 to mouse 7/human 11p14.3-p15.2 and KCNA1/Kv1.1 to human 12p13.
Randy S. Wymore, J. Korenberg, Keith D. Kinoshita, J. Aiyar +7 more
1994Genomics41 citations
Semantic Scholar
Characterization of the Transcription Unit of Mouse Kv1.4, a Voltage-gated Potassium Channel Gene*
Randy S. Wymore, Deborah Negulescu, Keith D. Kinoshita, K. Kalman +3 more
1996Journal of Biological Chemistry36 citations Open access
Semantic Scholar
Muscarinic receptor subtypes and signalling involved in the attenuation of isoprenaline-induced rat urinary bladder relaxation
L. Witte, Noach de Haas, M. Mammen, Eric L. Stangeland +3 more
2011Naunyn-Schmiedeberg's Archives of Pharmacology23 citations Open access
Semantic Scholar
A New Series of Orally Bioavailable Chemokine Receptor 9 (CCR9) Antagonists; Possible Agents for the Treatment of Inflammatory Bowel Disease.
S. Kalindjian, Sanjay Venkatachalapathi Kadnur, C. Hewson, C. Venkateshappa +8 more
2016Journal of Medicinal Chemistry18 citations Open access
Semantic Scholar
N-Acridin-9-yl-butane-1,4-diamine derivatives: high-affinity ligands of the alpha2delta subunit of voltage gated calcium channels.
Jongwon Lim, N. Stock, Richard Pracitto, Julia K. Boueres +8 more
2004Bioorganic & Medicinal Chemistry Letters13 citations Open access
Semantic Scholar
Potassium channels in leukocytes and toxins that block them : Structure, function and therapeutic implications
J. Aiyar
199911 citations
Semantic Scholar
Expedited SAR study of high-affinity ligands to the α2δ subunit of voltage-gated calcium channels : Generation of a focused library using a solution-phase Sn2Ar coupling methodology
Chixu Chen, B. Stearns, T. Hu, Naomi Anker +6 more
20069 citations Open access
Semantic Scholar
Dual-pharmacology bronchodilators for the treatment of COPD
J. R. Jacobsen, J. Aiyar, S. Hegde, Adam D. Hughes +1 more
20106 citations
Semantic Scholar
Structural and Biochemical Features of the Kv1.3 Potassium Channel: An Aid to Guided Drug Design
G. Chandy, Michael Strong, J. Aiyar, G. Gutman
19975 citations
Semantic Scholar
Abstract 3509: Novel dual inhibitors of LSD1-HDAC for treatment of cancer
D. Sivanandhan, S. Rajagopalan, S. Nair, Purushottam M. Dewang +15 more
20153 citations
Semantic Scholar
Identification and synthesis of [1,2,4]triazolo[3,4-a]phthalazine derivatives as high-affinity ligands to the alpha 2 delta-1 subunit of voltage gated calcium channel.
A. Lebsack, J. Gunzner, Bowei Wang, Richard Pracitto +7 more
2004Bioorganic & Medicinal Chemistry Letters3 citations
Semantic Scholar
Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels.
Tao Hu, B. Stearns, Brian T. Campbell, J. M. Arruda +8 more
2004Bioorganic & Medicinal Chemistry Letters2 citations Open access
Semantic Scholar
Comparing population-level humoral and cellular immunity to SARS-Cov-2 in Bangalore, India
Anup Malani, J. Aiyar, A. Sant, N. Kamran +5 more
2024Scientific Reports1 citations Open access
Semantic Scholar
Crosstalk between Heterologously Expressed M3-Muscarinic Receptors and β2Adrenoceptors.
J. Aiyar, J. Calixto, Cj Linnevers, M. Mammen
2009Asian Test Symposium1 citations
Semantic Scholar
Relationship between β2-Adrenoceptor Density and Bronchoprotection in Guinea Pigs Treated Acutely or Chronically with Indacaterol.
J. Aiyar, Cj Linnevers, A. Mcnamara, M. Mammen
2009Asian Test Symposium0 citations
Semantic Scholar
Expedited SAR study of high-affinity ligands to the alpha(2)delta subunit of voltage-gated calcium channels: Generation of a focused library using a solution-phase Sn2Ar coupling methodology.
Chixu Chen, B. Stearns, T. Hu, Naomi Anker +6 more
2006Bioorganic & Medicinal Chemistry Letters0 citations
Semantic Scholar

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