E. Topkan

Most-cited papers

1. Oral microbiome in head and neck squamous cell cancers: association or causation?

   E. Topkan, E. Somay, U. Selek

   2025Oral Oncology2 citations

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2. Prechemoradiotherapy number of natural teeth as a prognostic factor in patients with locally advanced nasopharyngeal cancer: A retrospective observational study

   E. Topkan, E. Somay, S. Başçıl, Duriye Ozturk +1 more

   2025Journal of International Medical Research2 citations Open access

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3. Exclusive radiologically determined myopenia does not equate to sarcopenia.

   E. Topkan, U. Selek

   2025Lung Cancer2 citations

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4. Comment on: “Combination of immunotherapy-based systemic therapy and radiotherapy achieves durable response and favorable survival in recurrent head and neck cancer”

   E. Topkan, E. Somay, U. Selek

   2026Therapeutic Advances in Medical Oncology1 citations Open access

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5. Heat Shock Protein 27 in Radiation-Induced Trismus: Mechanistic Insights and a Hypothesis-Generating Framework

   E. Topkan, E. Somay, Doga Topkan, S. Senyurek +2 more

   2026Biomedicines1 citations Open access

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6. Cannabis use disorder and lung cancer risk: Methodological considerations in interpretation.

   E. Topkan, Melis Selek, U. Selek

   2026Lung Cancer1 citations

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7. In Regard to Humbert-Vidan L et al.

   E. Topkan, E. Somay, U. Selek

   2026International Journal of Radiation Oncology, Biology, Physics1 citations

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8. Comment on: Late Cachexia or treatment-related muscle wasting in long-term HNSCC survivors?

   E. Topkan, E. Somay, U. Selek

   2026Clinics1 citations Open access

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9. Re: What nutritional interventions can effectively treat sarcopenia in older adults with cancer? A systematic review.

   E. Topkan, U. Selek

   2026Journal of Geriatric Oncology1 citations

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10. Defining Sarcopenia in Oncology by CT-Based Muscle Mass: The Clinical and Research Consequences of a Diagnostic Surrogate

    E. Topkan, E. Somay, Duriye Ozturk, U. Selek

    2026Diagnostics1 citations Open access

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11. Comment on Dosimetric Determinants of Locoregional Failure in Nasopharyngeal Carcinoma Treated with Definitive Intensity-Modulated Radiotherapy with or without Concomitant Chemotherapy.

    E. Topkan, E. Somay, U. Selek

    2026Asian Pacific Journal of Cancer Prevention1 citations Open access

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12. Beyond the Numbers: Inflammation as the Missing Link in Decayed, Missing, Filled Teeth-Based Buccal Mucosa Cancer Risk Models.

    E. Somay, E. Topkan, U. Selek

    2025JCO Global Oncology1 citations Open access

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13. CARWL score as a predictor of radiation-induced periodontitis in locally advanced head and neck cancer undergoing concurrent chemoradiotherapy

    S. Başçıl, E. Somay, Nilufer Kılıc Durankus, Şükran Şenyürek +3 more

    2025Biomolecules & biomedicine1 citations Open access

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14. Comment on: Association of Sarcopenia with Toxicity and Survival in Patients With Lung Cancer, a Multi-Institutional Study With External Dataset Validation.

    E. Topkan, Duriye Ozturk, U. Selek

    2025Clinical Lung Cancer1 citations

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15. Comment on "Osteoradionecrosis as a complication following post-operative intensity-modulated radiation therapy or proton therapy for oral cavity cancer".

    E. Topkan, E. Somay, Duriye Ozturk, U. Selek

    2025Oral Oncology1 citations

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16. In Regard to Grippin et al.

    E. Somay, S. Başçıl, E. Topkan, U. Selek

    2025International Journal of Radiation Oncology, Biology, Physics1 citations

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17. A higher number of chemotherapy cycles given during and after radiation is linked to increased rates of radiation-induced trismus in locally advanced nasopharyngeal cancer patients

    E. Somay, E. Topkan, S. Başçıl, Duriye Ozturk +1 more

    2025Discover Oncology1 citations Open access

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18. Factors Influencing Immunotherapy Outcomes in Cancer: Sarcopenia and Systemic Inflammation

    E. Topkan, Nilüfer Kılıç Durankuş, Şükran Şenyürek, U. Selek

    2025Cancer Control: Journal of the Moffitt Cancer Cente1 citations Open access

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19. Comment on: Concurrent chemoradiotherapy versus radiotherapy alone in postoperative high-risk adenoid cystic carcinoma of the head and neck: A propensity score-matched analysis

    E. Topkan, E. Somay, U. Selek

    2025Clinical and Translational Radiation Oncology1 citations Open access

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20. Comments on “Jaw‐in‐a‐Day Reconstruction: A Scoping Review of Clinical Outcomes and Evidence Gaps”

    E. Somay, E. Topkan, U. Selek

    2026Microsurgery0 citations Open access

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21. Tooth Extraction Timing After Head and Neck Radiotherapy: A Critical Reappraisal of Osteoradionecrosis Risk and Biological Vulnerability

    E. Topkan, E. Somay, S. Başçıl, U. Selek

    2026Methods and Protocols0 citations Open access

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22. Osteosarcopenia or a prognostic imaging phenotype? Construct validity before clinical interpretation.

    E. Topkan, E. Somay, Ugur Selekc

    2026Oral Oncology0 citations

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23. Threshold Validity of N3 Criteria in Nasopharyngeal Carcinoma: A Narrative Methodological Review of Pragmatic Cutoffs and Biologically Defensible Risk Boundaries

    E. Topkan, E. Somay, Melis Selek, U. Selek

    2026Clinics and Practice0 citations Open access

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24. Re: Ensemble learning-based radiomics model for predicting radiation-induced temporal lobe injury in nasopharyngeal carcinoma.

    E. Topkan, E. Somay, U. Selek

    2026Oral Oncology0 citations

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25. Dental Implants After Head and Neck Radiotherapy: From Chronological Waiting Rules to Implant-Bed-Specific Risk Stratification

    E. Topkan, E. Somay, S. Başçıl, U. Selek

    2026Healthcare0 citations Open access

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26. The Comprehensive Repair–Inflammation Index (CRII) Predicts Tooth Extraction After Chemoradiotherapy: A Continuous and Nonlinear Modeling Analysis

    E. Topkan, E. Somay, S. Başçıl, Duriye Ozturk +1 more

    2026Journal of Clinical Medicine0 citations Open access

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27. Response to: “A prospective pilot study to evaluate the impact of palliative radiotherapy in upfront inoperable/chemo unfit patients with extrahepatic biliary tract tumors” by Kumar et al. [1]

    E. Topkan, U. Selek

    2026Reports of Practical Oncology & Radiotherapy0 citations Open access

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28. Comment on “The Prognostic Significance of Sarcopenia Assessed by the Psoas Muscle Index in Multiple Myeloma patients.”

    E. Topkan, U. Selek

    2026Indian Journal of Hematology and Blood Transfusion0 citations Open access

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29. Tissue Resilience in Radiation-Induced Injury: A Hypothesis-Generating Review of Heat Shock Protein 27 in Osteoradionecrosis of the Jaw

    E. Topkan, Doga Topkan, E. Somay, Duriye Ozturk +2 more

    2026Radiation0 citations Open access

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30. Is myopenia sufficient to diagnose sarcopenia?

    E. Topkan, Duriye Ozturk, U. Selek

    2026The Oncologist0 citations Open access

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31. In Regard to Regan et al

    E. Topkan, E. Somay, U. Selek

    2026Advances in Radiation Oncology0 citations Open access

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32. Re: Van Diessen et al. Improved Overall Survival Due to Reduced Waiting Time in Nasopharyngeal Cancer Patients Treated with Chemoradiotherapy in Yogyakarta, Indonesia.

    E. Topkan, U. Selek

    2026Asian Pacific Journal of Cancer Prevention0 citations Open access

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33. Comment on low-dose fractionated radiotherapy during induction chemotherapy for node-positive locoregionally advanced nasopharyngeal carcinoma: a randomized phase II trial.

    E. Topkan, U. Selek

    2026Oral Oncology0 citations

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34. Re: “Comparative Evaluation of Upfront Surgery and Neoadjuvant Chemotherapy Followed by Surgery in Locally Advanced Oral Squamous Cell Carcinoma”

    E. Topkan, E. Somay, S. Başçıl, U. Selek

    2026Journal of Maxillofacial and Oral Surgery0 citations

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35. Re: Sarcopenia and postoperative morbidity in head and neck cancer: a systematic review and meta-analysis.

    E. Topkan, E. Somay, U. Selek

    2026American Journal of Otolaryngology0 citations Open access

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36. Comment on: “Impact of Depth of Invasion in Node‐Negative Oral Tongue Cancer Treated With Surgery Alone”

    E. Topkan, E. Somay, U. Selek

    2026Kaohsiung Journal of Medical Sciences0 citations Open access

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37. Comment on: Prognostic stratification using the Aarhus Composite Biomarker Score in recurrent and metastatic head and neck squamous cell carcinoma.

    E. Topkan, E. Somay, U. Selek

    2026European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery0 citations

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38. Beyond Whole-Mandible Dosimetry: An FDI-Based Hemijaw and Multiscale Framework for Osteoradionecro-sis Risk Assessment

    E. Topkan, E. Somay, U. Selek

    2026Oral0 citations Open access

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39. Comment on Impact of metastasis-directed therapy for metachronous thoracic metastases following definitive (chemo)radiotherapy in p16-positive head and neck squamous cell carcinoma.

    E. Topkan, U. Selek

    2026Oral Oncology0 citations

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40. Comment on: ‘alpha‐lipoic acid as a preventive measure in radiation‐induced oral mucositis in head and neck cancer pAtients: a randomized controlled study’—methodological considerations

    E. Topkan, E. Somay, S. Başçıl

    2026British Journal of Clinical Pharmacology0 citations Open access

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41. Comment on: VMAT with CCC Algorithm Optimizes Trismus Prevention: Dose–Response Analysis of Jaw Muscles Dmean and Dmax in T3–T4 Nasopharyngeal Carcinoma

    E. Topkan, E. Somay, U. Selek

    2026Technology in Cancer Research and Treatment0 citations Open access

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42. Heat Shock Protein 27 as a Candidate Mediator of Radiation-Induced Periodontitis: Mechanistic Rationale and Translational Perspectives

    E. Somay, Doga Topkan, E. Topkan, S. Başçıl +2 more

    2026Oral0 citations Open access

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43. Comparative Prognostic Performance of CARWL and Naples Prognostic Score in Stage IIIC Non-Small Cell Lung Cancer Treated with Definitive Chemoradiotherapy

    E. Topkan, Duriye Ozturk, U. Selek

    2026Medical Science0 citations Open access

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44. The Oxygenation–Nutritional–Inflammatory (ONI) index and the risk of osteoradionecrosis of the jaw in locally advanced nasopharyngeal carcinoma: a continuous multidimensional modeling analysis

    E. Topkan, E. Somay, S. Başçıl, U. Selek

    2026BMC Cancer0 citations Open access

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45. The Host Tissue Repair Vulnerability Index (HTRVI): A Composite Biomarker for Predicting Osteoradionecrosis in Locally Advanced Nasopharyngeal Carcinoma

    E. Somay, E. Topkan, S. Başçıl, U. Selek

    2026Medical Science0 citations Open access

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46. Comment on "Elective neck dissection and adjuvant therapy in N0 major salivary gland cancer: an analysis of the SEER cancer database".

    E. Topkan, U. Selek

    2026Oral Oncology0 citations

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47. RE: Among Patients With Oral Cavity Squamous Cell Carcinoma Does Timing of Adjuvant Radiation Therapy Affect Survival?

    E. Topkan, E. Somay, S. Başçıl, U. Selek

    2026Journal of oral and maxillofacial surgery0 citations

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48. Comment on: The Application of Adjuvant Radiotherapy in pN1 OSCC Patients Without Adverse Pathologic Features

    E. Topkan, E. Somay, U. Selek

    2026Oral Diseases0 citations Open access

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49. Comment on: Margin-To-Depth of Invasion Ratio: New Standard for T1/T2 OSCC Surgical Margin Assessment.

    E. Topkan, E. Somay, S. Başçıl, U. Selek

    2026Oral Diseases0 citations

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50. The HARP (Hemoglobin–Albumin–C-Reactive Protein) Index: A Biologically Designed Composite Biomarker for Continuous Prognostic Modeling in Locally Advanced Nasopharyngeal Carcinoma

    E. Topkan, E. Somay, S. Başçıl, Duriye Ozturk +1 more

    2026Diseases0 citations Open access

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