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R. Townley · SciRah

Researcher profile · Semantic Scholar

R. Townley

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R. Townley — researcher profile on SciRah

h-index: 30
Works: 208
Citations: 4,925

Most-cited papers

The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics.
M. Solér, J. Matz, R. Townley, R. Buhl +5 more
2001European Respiratory Journal863 citations Open access
Semantic Scholar
Preface
R. Townley
2003416 citations
Semantic Scholar
Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis.
T. Casale, W. Busse, J. Kline, Z. Ballas +7 more
2006Journal of Allergy and Clinical Immunology347 citations
Semantic Scholar
Omalizumab rapidly decreases nasal allergic response and FcεRI on basophils
Henry Lin, K. M. Boesel, D. T. Griffith, C. Prussin +4 more
2004256 citations Open access
Semantic Scholar
Omalizumab, an anti-IgE antibody, in the treatment of adults and adolescents with perennial allergic rhinitis.
P. Chervinsky, T. Casale, R. Townley, I. Tripathy +4 more
2003Annals of Allergy, Asthma & Immunology205 citations
Semantic Scholar
Budesonide delivered by Turbuhaler is effective in a dose-dependent fashion when used in the treatment of adult patients with chronic asthma.
W. Busse, P. Chervinsky, J. Condemi, W. Lumry +3 more
1998Journal of Allergy and Clinical Immunology186 citations Open access
Semantic Scholar
Airway hyperresponsiveness
R. Townley, M. Horiba
2003Clinical reviews in allergy and immunology183 citations
Semantic Scholar
Measurement of exhaled nitric oxide by three different techniques.
R. Robbins, A. Floreani, S. von Essen, J. H. Sisson +3 more
1996American Journal of Respiratory and Critical Care Medicine131 citations
Semantic Scholar
Omalizumab rapidly decreases nasal allergic response and FcepsilonRI on basophils.
Henry Lin, K. M. Boesel, D. T. Griffith, C. Prussin +4 more
2004Journal of Allergy and Clinical Immunology106 citations
Semantic Scholar
Omalizumab provides long-term control in patients with moderate-to-severe allergic asthma
R. Buhl, M. Solér, J. Matz, R. Townley +6 more
2002European Respiratory Journal102 citations Open access
Semantic Scholar
Fevipiprant, an oral prostaglandin DP2 receptor (CRTh2) antagonist, in allergic asthma uncontrolled on low-dose inhaled corticosteroids
E. Bateman, Alfredo G. Guerreros, F. Brockhaus, B. Holzhauer +3 more
2017European Respiratory Journal99 citations
Semantic Scholar
Exhaled nitric oxide in children with asthma receiving Xolair (omalizumab), a monoclonal anti-immunoglobulin E antibody.
P. Silkoff, F. Romero, N. Gupta, R. Townley +1 more
2004Pediatrics93 citations
Semantic Scholar
IL-13 and the IL-13 receptor as therapeutic targets for asthma and allergic disease.
Jesse Mitchell, V. Dimov, R. Townley
2010Current opinion in investigational drugs50 citations
Semantic Scholar
Role of periostin, FENO, IL-13, lebrikzumab, other IL-13 antagonist and dual IL-4/IL-13 antagonist in asthma
S. Agrawal, R. Townley
2014Expert Opinion on Biological Therapy46 citations
Semantic Scholar
The effect of BCG vaccine at birth on the development of atopy or allergic disease in young children.
R. Townley, I. Barlan, C. M. Patino, P. Vichyanond +8 more
2004Annals of Allergy, Asthma & Immunology44 citations
Semantic Scholar
Effect of loratadine on human eosinophil function in vitro.
R. Eda, H. Sugiyama, R. Hopp, A. Bewtra +1 more
1993Annals of allergy43 citations
Semantic Scholar
Glucocorticoids inhibit proliferation and interleukin-4 and interleukin-5 secretion by aeroallergen-specific T-helper type 2 cell lines.
I. Crocker, M. K. Church, S. Newton, R. Townley
1998Annals of Allergy, Asthma & Immunology35 citations
Semantic Scholar
CRTH2 antagonists in the treatment of allergic responses involving TH2 cells, basophils, and eosinophils.
R. Townley, S. Agrawal
2012Annals of Allergy, Asthma & Immunology30 citations
Semantic Scholar
Targeting Phosphoinositide 3-Kinase γ in Airway Smooth Muscle Cells to Suppress Interleukin-13-Induced Mouse Airway Hyperresponsiveness
Haihong Jiang, Yan Xie, P. Abel, M. Toews +3 more
2012Journal of Pharmacology and Experimental Therapeutics30 citations Open access
Semantic Scholar
Anti-interleukin-4 inhibits immunoglobulin E production in a murine model of atopic asthma.
Chang Yi Zhou, I. Crocker, Gary M. Koenig, F. Romero +1 more
1997Journal of Asthma30 citations
Semantic Scholar
Erratum: The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics (European Respiratory Journal (2001) vol. 18 (254-261))
M. Solér, J. Matz, R. Townley, R. Buhl +5 more
200125 citations
Semantic Scholar
Effect of terfenadine on human eosinophil and neutrophil chemotactic response and generation of superoxide.
R. Eda, R. Townley, R. Hopp
1994Annals of allergy25 citations
Semantic Scholar
Immunopharmacology of allergic diseases
R. Townley, D. Agrawal
199624 citations
Semantic Scholar
Elevated cAMP-phosphodiesterase in atopic disease: cause or effect?
R. Townley
1993Journal of Laboratory and Clinical Medicine22 citations
Semantic Scholar
Asthma pathogenesis, diagnosis, and management in the elderly.
M. Pasha, B. Sundquist, R. Townley
2017Allergy and Asthma Proceedings21 citations
Semantic Scholar
The effect of omalizumab on small airway inflammation as measured by exhaled nitric oxide in moderate-to-severe asthmatic patients.
M. Pasha, D. Jourd’heuil, F. Jourd'heuil, L. Mahon +8 more
2014Allergy and Asthma Proceedings20 citations
Semantic Scholar
Phosphodiesterase type 4 inhibitors, but not glucocorticoids, are more potent in suppression of cytokine secretion by mononuclear cells from atopic than nonatopic donors.
I. Crocker, S. Ohia, M. Church, R. Townley
1998Journal of Allergy and Clinical Immunology18 citations Open access
Semantic Scholar
Attenuation of allergic airway inflammation and associated pulmonary functions by mycobacterial antigens is independent of IgE in a mouse model of asthma
M. Hopfenspirger, S. Parr, R. Townley, D. Agrawal
200216 citations Open access
Semantic Scholar
Effect of interleukin 13 on bronchial hyperresponsiveness and the bronchoprotective effect of beta-adrenergic bronchodilators and corticosteroids.
R. Townley, P. Gendapodi, N. Qutna, J. Evans +2 more
2009Annals of Allergy, Asthma & Immunology14 citations
Semantic Scholar
Interleukin 13 and the beta-adrenergic blockade theory of asthma revisited 40 years later.
R. Townley
2007Annals of Allergy, Asthma & Immunology14 citations
Semantic Scholar
Allergic rhinitis: relationship to asthma: similarities, differences, and interactions.
R. Townley, Andrew Kiboneka
1998Annals of Allergy, Asthma & Immunology14 citations
Semantic Scholar
IL-13 and its genetic variants: effect on current asthma treatments.
R. Townley, M. Sapkota, K. Sapkota
2011Discover medicine12 citations
Semantic Scholar
Beclomethasone Decreases Elevations in Phosphodiesterase Activity in Human T Lymphocytes
I. Crocker, M. Church, S. Ohia, R. Townley
2000International Archives of Allergy and Immunology10 citations
Semantic Scholar
Tilarin in combination with astemizole
D. Bukstein, Robert Biondi, Malcolm M. Blumenthal, R. Dockhorn +9 more
1996Allergy. European Journal of Allergy and Clinical Immunology10 citations
Semantic Scholar
828 Phase I/II study of recombinant interleukin-4 receptor (IL-4R) in adult patients with moderate asthma
M. Hopfenspirger, S. Parr, R. Townley, D. Agrawal
20009 citations
Semantic Scholar
49 Anti-inflammatory properties of desloratadine (DCL): Effect on eosinophil chemotaxis, adhesion and release of superoxide anions
D. Agrawal, A. Berro, W. Kreutner, R. Townley
20009 citations
Semantic Scholar
Therapeutic potential of phosphodiesterase 4 inhibitors in allergic diseases.
I. Crocker, R. Townley
1999Drugs of Today9 citations
Semantic Scholar
The effect of RP 59227, a platelet-activating factor antagonist, against antigen challenge and eosinophil and neutrophil chemotaxis in asthmatics.
R. Townley, R. Eda, R. Hopp, A. K. Bewtra +1 more
1994Journal of Lipid Mediators and Cell Signalling8 citations
Semantic Scholar
Is sublingual immunotherapy "ready for prime time"?
R. Townley
2008Chest7 citations
Semantic Scholar
Omalizumab for pediatric asthma
R. Townley, S. Agrawal, K. Sapkota
2010Expert Opinion on Biological Therapy6 citations
Semantic Scholar
The profile of the cytokines secreted during the generation of T-helper cells from atopic asthmatic subjects.
I. Crocker, Kirtibala Gupta, R. Townley, Manzoor M. Khan
1998Journal of Asthma5 citations
Semantic Scholar
Beta-adrenergic receptors and mechanisms in asthma : The new long-acting beta-agonists
R. Townley
19964 citations Open access
Semantic Scholar
Omalizumab pretreatment prevents allergic reactions due to rush immunotherapy (RIT)
T. Casale, J. Kline, W. Busse, Z. Ballas +5 more
20053 citations
Semantic Scholar
Effect of Fluticasone and/or β-agonists on Airway Hyperresponsiveness (AHR) In Mice Either Sensitized to Allergen or Pre-treated with IL-13
R. Townley, P. Gendapodi, J. Evans, F. Romero
20072 citations
Semantic Scholar
The Origins and Characteristics of Asthma
R. Hopp, R. Townley
20062 citations
Semantic Scholar
What factors cause bronchial hyperresponsiveness? Airway inflammation and eosinophilia are only part of the puzzle.
R. Townley
2003Annals of Allergy, Asthma & Immunology2 citations
Semantic Scholar
Different role of IL-1β and IL-13 on airway responsiveness and response to β2-Agonist
M. Horiba, R. Townley
20022 citations
Semantic Scholar
427 Glucocorticoids inhibit leukotriene release by mixed leukocytes
I. Crocker, C.-Y. Zhou, W. Kreutner, A. Bewtra +1 more
19962 citations Open access
Semantic Scholar
Effect of Acute and Chronic Exposure to Tobacco Smoke (ETS) Upon Secretion of IL-13 and Bronchial Hyperresponsiveness (BHR)
N. Bastola, Jesse Mitchell, R. Townley
20101 citations
Semantic Scholar
The correct methacholine challenge delivery method?
R. Townley, R. Hopp, R. Rosenthal
2007Journal of Allergy and Clinical Immunology1 citations
Semantic Scholar

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