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S. Sung · SciRah

Researcher profile · Semantic Scholar

S. Sung

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S. Sung — researcher profile on SciRah

h-index: 25
Works: 54
Citations: 1,826

Most-cited papers

Discovery of a Novel Shp2 Protein Tyrosine Phosphatase Inhibitor
Li-Wei Chen, S. Sung, M. L. Richard Yip, H. Lawrence +5 more
2006Molecular Pharmacology279 citations
Semantic Scholar
Discovery of Marinopyrrole A (Maritoclax) as a Selective Mcl-1 Antagonist that Overcomes ABT-737 Resistance by Binding to and Targeting Mcl-1 for Proteasomal Degradation*
Kenichiro Doi, Rong-Shi Li, S. Sung, Hong-Wei Wu +14 more
2012Journal of Biological Chemistry151 citations Open access
Semantic Scholar
The BH3 α-Helical Mimic BH3-M6 Disrupts Bcl-XL, Bcl-2, and MCL-1 Protein-Protein Interactions with Bax, Bak, Bad, or Bim and Induces Apoptosis in a Bax- and Bim-dependent Manner*
Aslamuzzaman Kazi, Jia-Zhi Sun, Kenichiro Doi, S. Sung +8 more
2010Journal of Biological Chemistry119 citations Open access
Semantic Scholar
A SMALL MOLECULE E2F INHIBITOR BLOCKS GROWTH IN A MELANOMA CULTURE MODEL
Yi-Hong Ma, C. Kurtyka, S. Boyapalle, S. Sung +3 more
2008Cancer Research103 citations Open access
Semantic Scholar
The Nature of the Catalytic Domain of 2′-5′-Oligoadenylate Synthetases*
Saumendra N. Sarkar, Abhrajyoti Ghosh, Hong-Wu Wang, S. Sung +1 more
1999Journal of Biological Chemistry90 citations Open access
Semantic Scholar
Inhibitors of Src Homology-2 Domain containing Protein Tyrosine Phosphatase-2 (Shp2) Based on Oxindole Scaffolds
H. Lawrence, Roberta Pireddu, Li-Wei Chen, Yunting Luo +7 more
2008Journal of Medicinal Chemistry89 citations Open access
Semantic Scholar
Computational Validation of the Importance of Absolute Stereochemistry in Virtual Screening
W. Brooks, K. Daniel, S. Sung, W. Guida
2008Journal of Chemical Information and Modeling78 citations
Semantic Scholar
Fragment-Based and Structure-Guided Discovery and Optimization of Rho Kinase Inhibitors
Rong-Shi Li, Mathew P. Martin, Yan Liu, Binglin Wang +11 more
2012Journal of Medicinal Chemistry54 citations Open access
Semantic Scholar
Molecular dynamics simulations of synthetic peptide folding
S. Sung, Xiong-Wu Wu
1996Proteins: Structure, Function, and Bioinformatics51 citations
Semantic Scholar
Structures and energetics of monovalent ion–water microclusters
S. Sung, Peter C. Jordan
198651 citations
Semantic Scholar
Identification of an Active Sequence within the First Immunoglobulin Domain of Intercellular Cell Adhesion Molecule-1 (ICAM-1) That Interacts with Fibrinogen*
S. D'Souza, V. Byers-Ward, E. Gardiner, Hong-Wu Wang +1 more
1996Journal of Biological Chemistry50 citations Open access
Semantic Scholar
The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines
T. Dick, J. Hengst, T. Fox, Ashley L. Colledge +8 more
2015Journal of Pharmacology and Experimental Therapeutics43 citations Open access
Semantic Scholar
Gambogic acid inhibits multiple myeloma mediated osteoclastogenesis through suppression of chemokine receptor CXCR4 signaling pathways.
M. Pandey, V. Kale, Chunhua Song, S. Sung +4 more
2014Experimental Hematology43 citations Open access
Semantic Scholar
Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2)
Roberta Pireddu, K. Forinash, Nan N. Sun, Mathew P. Martin +7 more
2012MedChemComm43 citations Open access
Semantic Scholar
Identification of a Disruptor of the MDM2-p53 Protein-Protein Interaction Facilitated by High-throughput in Silico Docking
H. Lawrence, Zhen-Yu Li, M. L. Richard Yip, S. Sung +7 more
2009Bioorganic & Medicinal Chemistry Letters41 citations Open access
Semantic Scholar
Folding simulations of alanine-based peptides with lysine residues.
S. Sung
1995Biophysical Journal41 citations Open access
Semantic Scholar
Why is gramicidin valence selective? A theoretical study.
S. Sung, Peter C. Jordan
1987Biophysical Journal40 citations Open access
Semantic Scholar
Molecular Dynamics Simulations of Three-Strand β-Sheet Folding
Hong-Wu Wang, S. Sung
200037 citations
Semantic Scholar
Inhibition of cellular Shp2 activity by a methyl ester analog of SPI-112
Li-Wei Chen, Daniele Pernazza, Latanya M. Scott, H. Lawrence +8 more
2010Biochemical Pharmacology36 citations Open access
Semantic Scholar
Virtual Target Screening: Validation Using Kinase Inhibitors
Daniel N. Santiago, Yuri Pevzner, A. Durand, MinhPhuong Tran +6 more
2012Journal of Chemical Information and Modeling35 citations Open access
Semantic Scholar
Targeting Sphingosine-1-Phosphate Receptors in Cancer
R. Watters, Hong-Gang Wang, S. Sung, T. Loughran +1 more
2011Anti-Cancer Agents in Medicinal Chemistry35 citations Open access
Semantic Scholar
Helix folding simulations with various initial conformations.
S. Sung
1994Biophysical Journal33 citations Open access
Semantic Scholar
A novel selective multikinase inhibitor of ROCK and MRCK effectively blocks cancer cell migration and invasion
V. Kale, J. Hengst, D. Desai, T. Dick +6 more
2014Cancer Letters30 citations Open access
Semantic Scholar
Molecular dynamics simulations of β‐hairpin folding
Hong-Wu Wang, J. Varady, Lily Ng, S. Sung
199927 citations Open access
Semantic Scholar
Monte Carlo Simulations of β-Hairpin Folding at Constant Temperature
S. Sung
199925 citations Open access
Semantic Scholar
A novel dual inhibitor of microtubule and Bruton's tyrosine kinase inhibits survival of multiple myeloma and osteoclastogenesis.
M. Pandey, Krishne Gowda, S. Sung, T. Abraham +4 more
2017Experimental Hematology23 citations Open access
Semantic Scholar
Constraint dynamics algorithm for simulation of semiflexible macromolecules
Xiong-Wu Wu, S. Sung
1998Journal of Computational Chemistry22 citations Open access
Semantic Scholar
Simulation of peptide folding with explicit water—a mean solvation method
Xiong-Wu Wu, S. Sung
1999Proteins: Structure, Function, and Bioinformatics17 citations Open access
Semantic Scholar
Peptide folding driven by Van der Waals interactions
S. Sung
2015Protein Science16 citations Open access
Semantic Scholar
Effects of turn residues on beta-hairpin folding--a molecular dynamics study.
Hong-Wu Wang, S. Sung
1999Biopolymers13 citations
Semantic Scholar
Theoretical study of the antiparallel double-stranded helical dimer of gramicidin as an ion channel.
S. Sung, Peter C. Jordan
1988Biophysical Journal13 citations Open access
Semantic Scholar
Allosteric Effects Potentiating the Release of the Second Fibrinopeptide A from Fibrinogen by Thrombin*
J. Shainoff, G. Smejkal, P. Dibello, S. Sung +2 more
2002Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Molecular dynamics simulations of helix folding: The effects of amino acid substitution
S. Sung, Xiong-Wu Wu
199712 citations
Semantic Scholar
Characterization of a Novel Anti-Cancer Compound for Astrocytomas
Sang Y. Lee, Becky Slagle-Webb, Elias B. Rizk, Akshal S. Patel +3 more
2014PLoS ONE11 citations Open access
Semantic Scholar
The interaction of Cl- with a gramicidin-like channel.
S. Sung, Peter C. Jordan
1987Biophysical Chemistry11 citations
Semantic Scholar
Pyoluteorin derivatives induce Mcl-1 degradation and apoptosis in hematological cancer cells
Kenichiro Doi, Krishne Gowda, Qiang Liu, Jyh M. Lin +6 more
2014Cancer Biology & Therapy9 citations Open access
Semantic Scholar
The channel properties of possible gramicidin dimers.
S. Sung, Peter C. Jordan
1989Journal of Theoretical Biology9 citations
Semantic Scholar
The close ties between organometallic chemistry, surface science, and the solid state
R. Hoffmann, S. D. Wijeyesekera, S. Sung
19868 citations Open access
Semantic Scholar
Abstract 3904: Pyridylthiazole-based ureas as inhibitors of Rho-associated protein kinases
Roberta Pireddu, K. Forinash, Nan N. Sun, Mathew P. Martin +7 more
20127 citations
Semantic Scholar
Targeting of Chk2 as a countermeasure to dose-limiting toxicity triggered by topoisomerase-II (TOP2) poisons
P. Gokare, A. Navaraj, Sheng-Liang Zhang, N. Motoyama +2 more
2016OncoTarget5 citations Open access
Semantic Scholar
An efficient approach to estimating thermodynamic properties of fluid mixtures in molecular simulation
Xiong-Wu Wu, S. Sung
19964 citations
Semantic Scholar
A theoretical study of double ion occupancy in a gramicidin-like channel
S. Sung, Peter C. Jordan
19884 citations
Semantic Scholar
Dielectric screening effect of electronic polarization and intramolecular hydrogen bonding
S. Sung
2017Protein Science3 citations Open access
Semantic Scholar
Monte Carlo simulations of beta-hairpin folding at constant temperature.
S. Sung
1999Biophysical Journal3 citations
Semantic Scholar
Molecular dynamics simulations of beta-hairpin folding.
Hong-Wu Wang, J. Varady, Lily Ng, S. Sung
1999Proteins: Structure, Function, and Bioinformatics2 citations
Semantic Scholar
Abstract 3786: Gambogic acid inhibits chemokine receptor CXCR4 signaling pathways and osteoclastogenesis in multiple myeloma
M. Pandey, V. Kale, Chunhua Song, S. Sung +3 more
20140 citations
Semantic Scholar
Abstract 1805: Characterization of pyoluteorin derivatives as Mcl-1 antagonists
Kenichiro Doi, Krishne Gowda, Qiang Liu, S. Sung +4 more
20140 citations
Semantic Scholar
Abstract A130: Fragment-based discovery and optimization of Rho kinase inhibitors.
Yan Liu, Binglin Wang, Ronil A Patel, Nan N. Sun +5 more
20110 citations
Semantic Scholar
Abstract A132: S1PR5 structural model and its application in drug discovery.
S. Sung
20110 citations
Semantic Scholar
Abstract 761: The development of cell permeable Shp2 PTP inhibitors
H. Lawrence, Li-Wei Chen, Daniele Pernazza, Latanya M. Scott +8 more
20100 citations
Semantic Scholar

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