Eli R. Schuman

Most-cited papers

1. Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators

   B. Hubbard, A. P. Gomes, H. Dai, Jun Li +26 more

   2013Science623 citations Open access

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2. Identification of small molecule inhibitors of pyruvate kinase M2

   M. V. Vander Heiden, H. Christofk, Eli R. Schuman, Alexander O. Subtelny +4 more

   2009Biochemical Pharmacology253 citations Open access

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3. Killing by Bactericidal Antibiotics Does Not Depend on Reactive Oxygen Species

   A. P. Gomes, H. Dai, Jun Li, Thomas Considine +20 more

   245 citations

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4. Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3.

   J. Disch, G. Evindar, Cynthia H. Chiu, Charles A. Blum +14 more

   2013Journal of Medicinal Chemistry198 citations Open access

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5. Identification of novel small molecules that elevate Klotho expression

   G. King, Ci-Di Chen, Mickey Huang, Ella Zeldich +6 more

   2012Biochemical Journal55 citations Open access

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6. Development of a Mechanism-based HTS Assay for Leucine Rich Repeat Kinase2—Discovery of LRRK2 Inhibitors

   Min Liu, S. Poulose, Eli R. Schuman, Alexandra D Zaitsev +7 more

   2010Analytical Biochemistry34 citations Open access

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7. Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo.

   T. Halkina, Jaclyn L. Henderson, Edward Y. S. Lin, Martin K. Himmelbauer +22 more

   2021Journal of Medicinal Chemistry32 citations Open access

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8. A High-Throughput Small-Molecule Ligand Screen Targeted to Agonists and Antagonists of the G-Protein-Coupled Receptor GPR54

   W. Kuohung, M. Burnett, Deepa Mukhtyar, Eli R. Schuman +4 more

   2010Journal of biomolecular screening24 citations Open access

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9. Identification of Small Molecule Inhibitors of β–Amyloid Cytotoxicity through a Cell-based High-Throughput Screening Platform

   K. Seyb, Eli R. Schuman, Jake Ni, Mickey Huang +2 more

   2008Journal of biomolecular screening17 citations Open access

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10. Discovery of Phospholipase D Inhibitors with Improved Drug-like Properties and Central Nervous System Penetrance.

    Tricia L. May-Dracka, Fang Gao, Brian T. Hopkins, X. Hronowski +17 more

    2022ACS Medicinal Chemistry Letters10 citations Open access

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11. A High-Throughput Screening Method for Small-Molecule Inhibitors of the Aberrant Mutant SOD1 and Dynein Complex Interaction

    Xiao-Hu Tang, K. Seyb, Mickey Huang, Eli R. Schuman +3 more

    2011Journal of biomolecular screening9 citations Open access

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12. Development of a Mechanism-based HTS Assay for Leucine Rich Repeat Kinase2—Discovery of LRRK2 Inhibitors

    Min Liu, S. Poulose, Eli R. Schuman, Alexandra D Zaitsev +8 more

    20110 citations

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