A. Crujeiras

Most-cited papers

1. Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants

   Mariachiara James Gretchen A Bin Goodarz Yuan Honor Melanie J Di Cesare Bentham Stevens Zhou Danaei Lu Bixby Cow, M. di Cesare, J. Bentham, G. Stevens +496 more

   2016The Lancet4,631 citations Open access

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2. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

   Bin Rodrigo M Goodarz Leanne M Christopher J Gretchen Zhou Carrillo-Larco Danaei Riley Paciorek Stevens, Bin Zhou, Rodrigo M. Carrillo-Larco, G. Danaei +496 more

   2021The Lancet2,869 citations Open access

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3. Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults

   Nowell H Rosie K Bin Rachel A Anu James E Christopher J V Phelps Singleton Zhou Heap Mishra Bennett Paciorek, Nowell H Rosie K Bin Rachel A Anu James E Christopher J V Phelps Singleton Zhou Heap Mishra Bennett Paciorek, N. H. Phelps, Rosie K. Singleton +496 more

   2024The Lancet1,934 citations Open access

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4. Worldwide trends in diabetes prevalence and treatment from 1990 to 2022: a pooled analysis of 1108 population-representative studies with 141 million participants

   Bin Zhou, Archie W. Rayner, Edward W. Gregg, Kate E. Sheffer +496 more

   2024The Lancet831 citations Open access

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5. Leptin, Obesity, and Leptin Resistance: Where Are We 25 Years Later?

   A. G. Izquierdo, A. Crujeiras, F. Casanueva, M. Carreira

   2019Nutrients450 citations Open access

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6. Body Composition Changes After Very-Low-Calorie Ketogenic Diet in Obesity Evaluated by 3 Standardized Methods

   D. Gómez-Arbeláez, D. Bellido, A. Castro, Lucía Ordóñez-Mayán +6 more

   2017Journal of Clinical Endocrinology and Metabolism190 citations

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7. Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

   Bin Zhou, J. Bentham, M. di Cesare, Honor Bixby +496 more

   2017The Lancet185 citations Open access

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8. Obesity treatment by very low-calorie-ketogenic diet at two years: reduction in visceral fat and on the burden of disease

   B. Moreno, A. Crujeiras, D. Bellido, I. Sajoux +1 more

   2016Endocrine185 citations

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9. Effect of A Very Low-Calorie Ketogenic Diet on Food and Alcohol Cravings, Physical and Sexual Activity, Sleep Disturbances, and Quality of Life in Obese Patients

   A. Castro, D. Gómez-Arbeláez, A. Crujeiras, Roser Granero +6 more

   2018Nutrients128 citations Open access

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10. Resting metabolic rate of obese patients under very low calorie ketogenic diet

    D. Gómez-Arbeláez, A. Crujeiras, A. Castro, M. Martínez Olmos +6 more

    2018Nutrition and Metabolism121 citations Open access

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11. DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese patients

    A. Crujeiras, Á. Díaz-Lagares, J. Sandoval, F. Milagro +8 more

    2017Scientific Reports101 citations Open access

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12. Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c

    Bin Zhou, Kate E. Sheffer, James E. Bennett, Edward W. Gregg +496 more

    2023Nature Medicine94 citations Open access

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13. Genome-wide DNA methylation pattern in visceral adipose tissue differentiates insulin-resistant from insulin-sensitive obese subjects.

    A. Crujeiras, Á. Díaz-Lagares, J. Moreno-Navarrete, J. Sandoval +6 more

    2016Translational Research: The Journal of Laboratory and Clinical Medicine85 citations Open access

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14. Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

    Maria LC Bin James E Rodrigo M Marisa K Andrea Honor Bet Iurilli Zhou Bennett Carrillo-Larco Sophiea Rodrig, M. L. Iurilli, Bin Zhou, J. Bennett +496 more

    2021eLife76 citations Open access

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15. “Food Addiction” in Patients with Eating Disorders is Associated with Negative Urgency and Difficulties to Focus on Long-Term Goals

    I. Wolz, Inés Hilker, Roser Granero, S. Jiménez-Murcia +6 more

    2016Frontiers in Psychology70 citations Open access

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16. Relevance of nutritional assessment and treatment to counteract cardiac cachexia and sarcopenia in chronic heart failure.

    A. Fernández-Pombo, Gemma Rodríguez-Carnero, A. Castro, A. Cantón-Blanco +4 more

    2021Clinical Nutrition68 citations Open access

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17. Food Addiction in Bulimia Nervosa: Clinical Correlates and Association with Response to a Brief Psychoeducational Intervention.

    Inés Hilker, I. Sánchez, T. Steward, S. Jiménez-Murcia +9 more

    2016European eating disorders review67 citations Open access

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18. General and abdominal adiposity and hypertension in eight world regions: a pooled analysis of 837 population-based studies with 7·5 million participants

    Bin Zhou, James E. Bennett, Aidan P. Wickham, Rosie K. Singleton +496 more

    2024The Lancet61 citations Open access

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19. National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries

    Cristina Rod Bin Honor Goodarz Mariachiara Kari Kaveh James Taddei Jackson Zhou Bixby Danaei Di Cesare Kuulasm, C. Taddei, R. Jackson, Bin Zhou +358 more

    2019International Journal of Epidemiology58 citations Open access

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20. Epigenetic silencing of TGFBI confers resistance to trastuzumab in human breast cancer

    S. Palomeras, Á. Díaz-Lagares, G. Viñas, F. Setien +8 more

    2019Breast Cancer Research58 citations Open access

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21. Obesity-Related Epigenetic Changes After Bariatric Surgery

    A. G. Izquierdo, A. Crujeiras

    2019Frontiers in Endocrinology57 citations Open access

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22. Effect of a Very-Low-Calorie Ketogenic Diet on Circulating Myokine Levels Compared with the Effect of Bariatric Surgery or a Low-Calorie Diet in Patients with Obesity

    I. Sajoux, P. M. Lorenzo, D. Gómez-Arbeláez, María de Los Ángeles Zulet +8 more

    2019Nutrients56 citations Open access

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23. A two-gene epigenetic signature for the prediction of response to neoadjuvant chemotherapy in triple-negative breast cancer patients

    B. Pineda, Á. Díaz-Lagares, J. Pérez-Fidalgo, O. Burgués +6 more

    2019Clinical Epigenetics54 citations Open access

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24. Ketogenic diets as treatment of obesity and type 2 diabetes mellitus

    F. Casanueva, M. Castellana, D. Bellido, P. Trimboli +6 more

    2020Reviews in Endocrine & Metabolic Disorders52 citations

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25. Identification of an episignature of human colorectal cancer associated with obesity by genome-wide DNA methylation analysis

    A. Crujeiras, S. Morcillo, Á. Díaz-Lagares, J. Sandoval +8 more

    2018International Journal of Obesity51 citations

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26. Orexin and sleep quality in anorexia nervosa: Clinical relevance and influence on treatment outcome.

    S. Sauchelli, S. Jiménez-Murcia, I. Sánchez, N. Riesco +21 more

    2016Psychoneuroendocrinology51 citations Open access

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27. Visceral and subcutaneous adipose tissue express and secrete functional alpha2hsglycoprotein (fetuin a) especially in obesity

    D. Pérez-Sotelo, A. Roca-Rivada, M. Larrosa-García, C. Castelao +6 more

    2017Endocrine50 citations

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28. Translating cancer epigenomics into the clinic: focus on lung cancer

    J. Marí-Alexandre, Á. Díaz-Lagares, Maria Villalba, Ó. Juan +3 more

    2017Translational Research: The Journal of Laboratory and Clinical Medicine49 citations

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29. Epigenetic Effects of Healthy Foods and Lifestyle Habits from the Southern European Atlantic Diet Pattern: A Narrative Review

    P. M. Lorenzo, A. G. Izquierdo, Gemma Rodríguez-Carnero, A. Fernández-Pombo +8 more

    2022Advances in Nutrition48 citations Open access

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30. Immunomodulatory effect of a very-low-calorie ketogenic diet compared with bariatric surgery and a low-calorie diet in patients with excessive body weight.

    P. M. Lorenzo, I. Sajoux, A. G. Izquierdo, D. Gómez-Arbeláez +9 more

    2022Clinical Nutrition47 citations Open access

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31. Circadian gene methylation profiles are associated with obesity, metabolic disturbances and carbohydrate intake

    O. Ramos-López, M. Samblas, F. Milagro, J. Riezu-Boj +3 more

    2018Chronobiology International47 citations

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32. Adipose tissue inflammation and VDR expression and methylation in colorectal cancer

    D. Castellano-Castillo, S. Morcillo, M. Clemente-Postigo, A. Crujeiras +4 more

    2018Clinical Epigenetics46 citations Open access

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33. Decision Making Impairment: A Shared Vulnerability in Obesity, Gambling Disorder and Substance Use Disorders?

    N. Mallorquí-Bagué, A. B. Fagundo, S. Jiménez-Murcia, R. de la Torre +16 more

    2016PLoS ONE42 citations Open access

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34. Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting

    A. Capelo-Diz, Sofía Lachiondo-Ortega, David Fernández-Ramos, J. Cañas-Martin +57 more

    2023Cell Metabolism41 citations Open access

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35. Comparative Effects of Pterostilbene and Its Parent Compound Resveratrol on Oxidative Stress and Inflammation in Steatohepatitis Induced by High-Fat High-Fructose Feeding

    S. Gómez-Zorita, Maitane González-Arceo, Jenifer Trepiana, L. Aguirre +5 more

    2020Antioxidants40 citations Open access

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36. Obesity and menopause modify the epigenomic profile of breast cancer.

    A. Crujeiras, Á. Díaz-Lagares, O. Stefansson, M. Macías-González +11 more

    2017Endocrine-Related Cancer40 citations Open access

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37. The effects of bariatric surgery on clinical profile, DNA methylation, and ageing in severely obese patients

    Eliza Fraszczyk, M. Luijten, A. Spijkerman, H. Snieder +10 more

    2020Clinical Epigenetics39 citations Open access

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38. Acid–base safety during the course of a very low-calorie-ketogenic diet

    D. Gómez-Arbeláez, A. Crujeiras, A. Castro, A. Goday +8 more

    2017Endocrine39 citations Open access

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39. Epigenetic landscape in blood leukocytes following ketosis and weight loss induced by a very low calorie ketogenic diet (VLCKD) in patients with obesity.

    A. Crujeiras, A. G. Izquierdo, D. Primo, F. Milagro +8 more

    2021Clinical Nutrition37 citations Open access

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40. Reduced Plasma Orexin-A Concentrations are Associated with Cognitive Deficits in Anorexia Nervosa

    T. Steward, G. Mestre-Bach, Roser Granero, I. Sánchez +19 more

    2019Scientific Reports35 citations Open access

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41. Secreted factors derived from obese visceral adipose tissue regulate the expression of breast malignant transformation genes

    A. Crujeiras, B. Cabia, M. Carreira, M. Amil +10 more

    2016International Journal of Obesity34 citations

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42. Enduring Changes in Decision Making in Patients with Full Remission from Anorexia Nervosa.

    T. Steward, G. Mestre-Bach, Z. Agüera, Roser Granero +19 more

    2016European eating disorders review32 citations Open access

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43. An Epigenetic Signature in Adipose Tissue Is Linked to Nicotinamide N‐Methyltransferase Gene Expression

    A. Crujeiras, P. Pissios, J. Moreno-Navarrete, Á. Díaz-Lagares +6 more

    2018Molecular Nutrition & Food Research30 citations

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44. Associations between neuropsychological performance and appetite-regulating hormones in anorexia nervosa and healthy controls: Ghrelin's putative role as a mediator of decision-making.

    G. Paslakis, Z. Agüera, Roser Granero, I. Sánchez +18 more

    2019Molecular and Cellular Endocrinology28 citations Open access

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45. Oxidative Stress Induced by Excess of Adiposity Is Related to a Downregulation of Hepatic SIRT6 Expression in Obese Individuals

    M. Carreira, A. G. Izquierdo, M. Amil, F. Casanueva +1 more

    2018Oxidative Medicine and Cellular Longevity28 citations Open access

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46. Noninvasive early detection of colorectal cancer by hypermethylation of the LINC00473 promoter in plasma cell-free DNA

    J. Ruiz-Bañobre, A. Rodríguez-Casanova, N. Costa-Fraga, A. Bao-Caamano +20 more

    2022Clinical Epigenetics27 citations Open access

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47. Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer

    H. Boughanem, A. Cabrera-Mulero, P. Hernández‐Alonso, M. Clemente-Postigo +5 more

    2020Clinical Epigenetics27 citations Open access

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48. DNA methylome in visceral adipose tissue can discriminate patients with and without colorectal cancer

    A. G. Izquierdo, H. Boughanem, Á. Díaz-Lagares, I. Arranz-Salas +5 more

    2021Epigenetics25 citations Open access

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49. Role of epigenomic mechanisms in the onset and management of insulin resistance

    A. G. Izquierdo, A. Crujeiras

    2019Reviews in Endocrine & Metabolic Disorders24 citations

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50. Role and Diagnostic Performance of Host Epigenome in Respiratory Morbidity after RSV Infection: The EPIRESVi Study

    S. Pischedda, I. Rivero-Calle, A. Gómez-Carballa, M. Cebey-López +11 more

    2022Frontiers in Immunology23 citations Open access

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