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S. Ruan · SciRah

Researcher profile · Semantic Scholar

S. Ruan

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S. Ruan — researcher profile on SciRah

h-index: 17
Works: 41
Citations: 999

Most-cited papers

Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells.
A. Grau, Ling Zhang, Weixin Wang, S. Ruan +4 more
1997Cancer Research156 citations
Semantic Scholar
Overexpressed WAF1/Cip1 renders glioblastoma cells resistant to chemotherapy agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin.
S. Ruan, M. Okcu, Jiang-Ping Ren, Paul J. Chiao +3 more
1998Cancer Research90 citations
Semantic Scholar
ALKBH5-mediated m6A demethylation of GLUT4 mRNA promotes glycolysis and resistance to HER2-targeted therapy in breast cancer.
H. Liu, H. Lyu, Guan-Min Jiang, Dan-Yang Chen +10 more
2022Cancer Research87 citations Open access
Semantic Scholar
Murine CD4+ T lymphocyte subsets and host defense against Pneumocystis carinii.
J. Shellito, C. Tate, S. Ruan, J. Kolls
2000Journal of Infectious Diseases83 citations
Semantic Scholar
Overexpression of Bax gene sensitizes K562 erythroleukemia cells to apoptosis induced by selective chemotherapeutic agents
Tohru Kobayashi, S. Ruan, K. Clodi, K. Kliche +3 more
1998Oncogene76 citations Open access
Semantic Scholar
Differential p53 phosphorylation and activation of apoptosis-promoting genes Bax and Fas/APO-1 by irradiation and ara-C treatment
Tohru Kobayashi, S. Ruan, J. Jabbur, U. Consoli +6 more
1998Cell Death and Differentiation62 citations
Semantic Scholar
MEMORY CD4+T CELLS ARE REQUIRED FOR OPTIMAL NK CELL EFFECTOR FUNCTIONS AGAINST THE OPPORTUNISTIC FUNGAL PATHOGEN, PNEUMOCYSTIS MURINA
M. Kelly, M. Zheng, S. Ruan, J. Kolls +2 more
2012Journal of Immunology54 citations Open access
Semantic Scholar
Effect of alcohol consumption on host release of interleukin-17 during pulmonary infection with Klebsiella pneumoniae.
J. Shellito, M. Zheng, Peng Ye, S. Ruan +2 more
2001Alcoholism: Clinical and Experimental Research53 citations
Semantic Scholar
Local Delivery of the Viral Interleukin-10 Gene Suppresses Tissue Inflammation in Murine Pneumocystis carinii Infection
S. Ruan, C. Tate, Janet Lee, T. Ritter +2 more
2002Infection and Immunity44 citations Open access
Semantic Scholar
Interleukin-12 and Host Defense against Murine Pneumocystis Pneumonia
S. Ruan, L. Mckinley, M. Zheng, X. Rudner +3 more
2008Infection and Immunity41 citations Open access
Semantic Scholar
CXCR3 and IFN Protein-10 in Pneumocystis Pneumonia
F. McAllister, S. Ruan, C. Steele, M. Zheng +5 more
2006Journal of Immunology29 citations Open access
Semantic Scholar
Suppression of the Macrophage Proteasome by Ethanol Impairs MHC Class I Antigen Processing and Presentation
Alain D’Souza, S. Desai, X. Rudner, M. Kelly +2 more
2013PLoS ONE27 citations Open access
Semantic Scholar
Alcohol consumption increases susceptibility to pneumococcal pneumonia in a humanized murine HIV model mediated by intestinal dysbiosis.
Derrick R. Samuelson, R. Siggins, S. Ruan, A. Amedee +7 more
2018Alcohol26 citations Open access
Semantic Scholar
Oral immunization of mice with live Pneumocystis murina protects against Pneumocystis pneumonia
Derrick R. Samuelson, N. M. de la Rúa, T. Charles, S. Ruan +6 more
2016Journal of Immunology19 citations Open access
Semantic Scholar
Treatment with Interleukin-7 Restores Host Defense against Pneumocystis in CD4+ T-Lymphocyte-Depleted Mice
S. Ruan, Derrick R. Samuelson, Brigitte Assouline, M. Morre +1 more
2015Infection and Immunity19 citations Open access
Semantic Scholar
Upregulation of endogenous TRAIL-elicited apoptosis is essential for metformin-mediated antitumor activity against TNBC and NSCLC
Shuang Liu, Erik V. Polsdofer, Lukun Zhou, S. Ruan +6 more
2021Molecular Therapy: Oncolytics18 citations Open access
Semantic Scholar
HER3 targeting augments the efficacy of panobinostat in claudin-low triple-negative breast cancer cells
H. Lyu, Defu Hou, Hao Liu, S. Ruan +4 more
2023npj Precision Oncology17 citations Open access
Semantic Scholar
Kobayashi T, Ruan SB, Clodi K, Kliche KO, Shiku H, Andreeff M and Zhang WOverexpression of bax gene sensitizes K562 erythroleukemia cells to apoptosis induced by selective chemotherapeutic agents. Oncogene 16: 1587-1591
Tohru Kobayashi, S. Ruan, K. Clodi, K. Kliche +3 more
199817 citations
Semantic Scholar
HER3 functions as an effective therapeutic target in triple negative breast cancer to potentiate the antitumor activity of gefitinib and paclitaxel
H. Lyu, Fei Shen, S. Ruan, Cong-Cong Tan +3 more
2023Cancer Cell International16 citations Open access
Semantic Scholar
Lymphocyte apoptosis in murine Pneumocystis pneumonia
Xin-Yu Shi, Nicole J Lecapitaine, X. Rudner, S. Ruan +1 more
2009Respiratory Research12 citations Open access
Semantic Scholar
B Cell and Antibody Responses in Mice Induced by a Putative Cell Surface Peptidase of Pneumocystis murina Protect against Experimental Infection
S. Ruan, Yang Cai, A. Ramsay, David A. Welsh +2 more
2016Vaccine11 citations Open access
Semantic Scholar
Conditional expression of interferon-gamma to enhance host responses to pulmonary bacterial infection.
S. Ruan, E. Young, Milson J. Luce, J. Reiser +2 more
2006Pulmonary Pharmacology & Therapeutics10 citations
Semantic Scholar
Detection of p21WAF1/Cip1 in brain metastases
S. Ruan, G. Fuller, V. Levin, J. Bruner +1 more
2004Journal of Neuro-Oncology10 citations
Semantic Scholar
Trastuzumab-resistant breast cancer cells-derived tumor xenograft models exhibit distinct sensitivity to lapatinib treatment in vivo
Hao Liu, S. Ruan, M. Larsen, Cong-Cong Tan +2 more
2023Biological Procedures Online8 citations Open access
Semantic Scholar
Attenuation of WAF 1 / Cip 1 Expression by an Antisense Adenovirus Expression Vector Sensitizes Glioblastoma Cells to Apoptosis Induced by Chemotherapeutic Agents 1 , 3-Bis ( 2-chloroethyl )-1-nitrosourea and Cisplatin 1
S. Ruan, M. Okcu, R. Pong, M. Andreeff +3 more
19984 citations
Semantic Scholar
Subtype-specific HER3 enrichment in basal-like breast cancer is regulated via the GATA2/GATA3–FOXA1 axis
Cong-Cong Tan, H. Lyu, S. Ruan, Yakun Wu +3 more
2025Cancer Letters2 citations Open access
Semantic Scholar
Abstract 3272: Attenuation of HER3-EGFR signaling augments antitumor activity of panobinostat in triple negative breast cancer
H. Lyu, S. Ruan, Cong-Cong Tan, Bo-Lin Liu
2022Cancer Research2 citations
Semantic Scholar
Alcohol use and alcohol-associated dysbiosis increase susceptibility to pneumococcal pneumonia in a humanized murine HIV model
Derrick R. Samuelson, R. Siggins, S. Ruan, A. Amedee +2 more
20182 citations
Semantic Scholar
Inhibition of telomerase activity correlates with a decrease in the RNA component of telomerase during differentiation.
T. Kobayashi, K. Clodi, Y. Yang, S. Ruan +4 more
1997International Journal of Oncology2 citations
Semantic Scholar
Abstract 2969: Histone deacetylase (HDAC) inhibitors exhibit antitumor activity in triple negative breast cancer via suppression of HER3 triggered signaling
Cong-Cong Tan, H. Lyu, S. Ruan, Bo-Lin Liu
2022Cancer Research1 citations
Semantic Scholar
Role of Interleukin-23 in Host Defense Against Pneumocystis carinii Infection.
X. Rudner, S. Ruan, J. Shellito
2009Asian Test Symposium1 citations
Semantic Scholar
Abstract PO1-24-08: Targeting of HER3 potentiates the antitumor activity of paclitaxel against triple negative breast cancer
H. Lyu, S. Ruan, Cong-Cong Tan, Ann D. Thor +1 more
2024Cancer Research0 citations
Semantic Scholar
Abstract 1790: Herceptin-resistant breast cancer cells exhibits distinct sensitivity to lapatinib in in vivo tumor xenograft models
S. Ruan, H. Liu, H. Lyu, Cong-Cong Tan +1 more
2022Cancer Research0 citations
Semantic Scholar
Metformin-induced TRAIL Upregulation Promotes Apoptosis in Triple Negative Breast Cancer and Non-small Cell Lung Cancer Cells
Shuangge Liu, Erik V. Polsdofer, Lukun Zhou, S. Ruan +6 more
20200 citations Open access
Semantic Scholar
Pneumoniaand IFN Protein-10 in Pneumocystis
E. Shellito, J. Kolls, L. Mckinley, L. Ulrich +3 more
20130 citations
Semantic Scholar
This information is current as Pneumocystis murina the Opportunistic Fungal Pathogen Optimal NK Cell Effector Functions against T Cells Are Required for + Memory CD 4
M. Kelly, M. Zheng, S. Ruan, J. Kolls +2 more
20120 citations
Semantic Scholar
Treatment With IL-7 Restores Host Defense Against Pneumocystis In Mice Depleted Of CD4+ T-Lymphocytes
J. Shellito, S. Ruan
2011Asian Test Symposium0 citations
Semantic Scholar
Absence of Pro-Apoptotic Bim Promotes Accumulation of Pulmonary T-Lymphocytes and Enhances Clearance of Pneumocystis carinii Infection in Mice.
S. Ruan, X. Rudner, J. Shellito
2009Asian Test Symposium0 citations
Semantic Scholar
This information is current as Pneumonia Pneumocystis CXCR 3 and IFN Protein-10 in
Florencia McAllister, S. Ruan, C. Steele, M. Zheng +5 more
20060 citations
Semantic Scholar
Induction Ofp 2 Jwaf . l Expression and Growth Inhibition by Transforming Growth Factor 1 @ Involve the Tumor Suppressor Gene DPC 4 in Human Pancreatic Adenocarcinoma Cells
A. Grau, Ling Zhang, Weixin Wang, S. Ruan +3 more
20060 citations
Semantic Scholar
BALB/c Mice Have Exaggerated IL-10 Response to Murine P. carinii.
D. Barstow, S. Ruan, X. Rudner, J. Shellito
20060 citations
Semantic Scholar

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