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B. Fife · SciRah

Researcher profile · Semantic Scholar

B. Fife

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B. Fife — researcher profile on SciRah

h-index: 40
Works: 130
Citations: 8,635

Most-cited papers

T Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes
A. Burrack, Tijana Martinov, B. Fife
2017Frontiers in Endocrinology283 citations Open access
Semantic Scholar
Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory
L. Beura, Jason S. Mitchell, E. Thompson, J. Schenkel +8 more
2018Nature Immunology246 citations Open access
Semantic Scholar
CD4+ T cell anergy prevents autoimmunity and generates regulatory T cell precursors
Lokesh A. Kalekar, Shirdi E. Schmiel, Sarada L. Nandiwada, Wing Y. Lam +11 more
2016Nature Immunology230 citations Open access
Semantic Scholar
T cells in non-lymphoid tissues give rise to lymph node resident memory T cells
L. Beura, Sathi P. Wijeyesinghe, E. Thompson, M. Macchietto +8 more
2018Immunity227 citations Open access
Semantic Scholar
Limited proliferation capacity of aorta intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression
Jesse W. Williams, Konstantin Zaitsev, Ki-Wook Kim, Stoyan Ivanov +14 more
2020Nature Immunology189 citations Open access
Semantic Scholar
Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality.
A. Saha, K. Aoyama, P. Taylor, Brent H. Koehn +14 more
2013Blood172 citations Open access
Semantic Scholar
T cell receptor cross-reactivity between similar foreign and self peptides influences naïve cell population size and autoimmunity
Ryan W. Nelson, Daniel J. Beisang, N. Tubo, T. Dileepan +9 more
2015Immunity167 citations Open access
Semantic Scholar
Polyclonal CD4+ T cell tolerance is established by distinct mechanisms, according to self-peptide expression patterns
D. Malhotra, Jonathan L. Linehan, T. Dileepan, You Jeong Lee +8 more
2016Nature Immunology166 citations Open access
Semantic Scholar
Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes
Kevin C. Osum, A. Burrack, Tijana Martinov, N. Sahli +7 more
2018Scientific Reports129 citations Open access
Semantic Scholar
Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset.
Jan Hülsdünker, Katja J. Ottmüller, H. Neeff, M. Koyama +16 more
2018Blood117 citations Open access
Semantic Scholar
Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.
A. Saha, Roddy S. O'Connor, G. Thangavelu, S. Lovitch +31 more
2016Journal of Clinical Investigation86 citations Open access
Semantic Scholar
Cutting Edge: IL-12 and Type I IFN Differentially Program CD8 T Cells for Programmed Death 1 Re-expression Levels and Tumor Control
Michael Y. Gerner, L. Heltemes-Harris, B. Fife, M. Mescher
2013Journal of Immunology74 citations Open access
Semantic Scholar
Landscape review of current HIV ‘kick and kill’ cure research - some kicking, not enough killing
K. Thorlund, Marc S. Horwitz, B. Fife, R. Lester +1 more
2017BMC Infectious Diseases71 citations Open access
Semantic Scholar
Most Microbe-specific Naïve CD4+ T Cells Produce Memory Cells During Infection
N. Tubo, B. Fife, Antonio J. Pagán, Dmitri I. Kotov +2 more
2016Science63 citations Open access
Semantic Scholar
Tregs with an MHC class II peptide–specific chimeric antigen receptor prevent autoimmune diabetes in mice
Justin A. Spanier, Vivian C. W. Fung, Christine M. Wardell, Mohannad H. Alkhatib +11 more
2023Journal of Clinical Investigation56 citations Open access
Semantic Scholar
TCR affinity biases Th cell differentiation by regulating CD25, Eef1e1, and Gbp2
Dmitri I. Kotov, Jason S. Mitchell, T. Pengo, C. Ruedl +4 more
2019Journal of Immunology55 citations Open access
Semantic Scholar
Increased Effector Memory Insulin-Specific CD4+ T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes
Justin A. Spanier, N. Sahli, Joseph C. Wilson, Tijana Martinov +8 more
2017Diabetes48 citations Open access
Semantic Scholar
Cutting Edge: Identification of Autoreactive CD4+ and CD8+ T Cell Subsets Resistant to PD-1 Pathway Blockade
Kristen E. Pauken, Christine E. Nelson, Tijana Martinov, Justin A. Spanier +9 more
2015Journal of Immunology45 citations Open access
Semantic Scholar
Cutting Edge: Type 1 Diabetes Occurs despite Robust Anergy among Endogenous Insulin-Specific CD4 T Cells in NOD Mice
Kristen E. Pauken, Jonathan L. Linehan, Justin A. Spanier, N. Sahli +6 more
2013Journal of Immunology45 citations Open access
Semantic Scholar
Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function
J. W. Choi, Sita S. Withers, Hong Chang, Justin A. Spanier +9 more
2020PLoS ONE43 citations Open access
Semantic Scholar
The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease
Cameron McDonald-Hyman, James T. Muller, Michael Loschi, G. Thangavelu +22 more
2018Journal of Clinical Investigation41 citations Open access
Semantic Scholar
Programmed death-1 culls peripheral accumulation of high affinity autoreactive CD4 T cells to protect against autoimmunity
Tony T. Jiang, Tijana Martinov, L. Xin, Jeremy M. Kinder +3 more
2016Cell Reports41 citations Open access
Semantic Scholar
Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes
E. Dirice, Sevim Kahraman, D. D. De Jesus, Abdelfattah El Ouaamari +20 more
2019Nature Metabolism39 citations Open access
Semantic Scholar
Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment
Justin A. Spanier, Daniel R. Frederick, Justin J. Taylor, James R. Heffernan +9 more
2016Nature Communications32 citations Open access
Semantic Scholar
Adoptive T-cell therapy with IL-12 pre-conditioned low avidity T-cells prevents exhaustion and results in enhanced T-cell activation, tumor clearance, and decreased risk for autoimmunity.
C. Tucker, Jason S. Mitchell, Tijana Martinov, B. Burbach +6 more
2020Journal of Immunology31 citations Open access
Semantic Scholar
Isolation of Infiltrating Leukocytes from Mouse Skin Using Enzymatic Digest and Gradient Separation.
Charles J. Benck, Tijana Martinov, B. Fife, D. Chatterjea
2016Journal of Visualized Experiments31 citations Open access
Semantic Scholar
Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance
Jessica K. Fiege, Ian A. Stone, Rebekah E. Dumm, Barbara M. Waring +5 more
2019PLoS Pathogens29 citations Open access
Semantic Scholar
Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes
Kevin C. Osum, A. Burrack, Tijana Martinov, N. Sahli +7 more
2018Scientific Reports29 citations Open access
Semantic Scholar
PD-1 pathway-mediated regulation of islet-specific CD4+ T cell subsets in autoimmune diabetes
Tijana Martinov, Justin A. Spanier, Kristen E. Pauken, B. Fife
2016Immunoendocrinology28 citations Open access
Semantic Scholar
Tropism for ciliated cells is the dominant driver of influenza viral burst size in the human airway
Shanley N. Roach, Frances K. Shepherd, C. Mickelson, Jessica K. Fiege +7 more
2024Proceedings of the National Academy of Sciences of the United States of America27 citations
Semantic Scholar
Reprogramming responsiveness to checkpoint blockade in dysfunctional CD8 T cells
Christine E. Nelson, L. Mills, Jennifer L. McCurtain, E. Thompson +5 more
2019Proceedings of the National Academy of Sciences of the United States of America26 citations Open access
Semantic Scholar
Eradication of Established Tumors by Chemically Self-Assembled Nanoring (CSAN) Labelled T Cells
Jacob Petersburg, Jing-Jing Shen, Clifford M. Csizmar, Katherine A. Murphy +5 more
2018ACS Nano26 citations Open access
Semantic Scholar
Cutting Edge: Dual TCRα Expression Poses an Autoimmune Hazard by Limiting Regulatory T Cell Generation
N. Schuldt, J. Auger, Justin A. Spanier, Tijana Martinov +4 more
2017Journal of Immunology26 citations Open access
Semantic Scholar
CAR Treg cells mediate linked suppression and infectious tolerance in islet transplantation in mice.
Christine M. Wardell, Vivian C. W. Fung, Eleanor Chen, Manjurul Haque +7 more
2025Science Translational Medicine22 citations
Semantic Scholar
Type 1 diabetes pathogenesis and the role of inhibitory receptors in islet tolerance
Tijana Martinov, B. Fife
2019Annals of the New York Academy of Sciences22 citations Open access
Semantic Scholar
Interstitial migration of CD8αβ T cells in the small intestine is dynamic and is dictated by environmental cues
E. Thompson, Jason S. Mitchell, L. Beura, David J. Torres +6 more
2019Cell Reports21 citations Open access
Semantic Scholar
CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes
Jason S Mitchell, Justin A. Spanier, Alexander J. Dwyer, T. Knutson +12 more
2024Immunity20 citations Open access
Semantic Scholar
Programmed death-1 restrains the germinal center in type 1 diabetes
Tijana Martinov, Linnea Swanson, Elise R. Breed, C. Tucker +9 more
2019Journal of Immunology20 citations Open access
Semantic Scholar
Repeated hapten exposure induces persistent tactile sensitivity in mice modeling localized provoked vulvodynia
Jasmine Landry, Tijana Martinov, Hanna Mengistu, Jyothi Dhanwada +8 more
2017PLoS ONE19 citations Open access
Semantic Scholar
T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction.
Michelle J. Smith, D. Reichenbach, Sarah L. Parker, Megan J. Riddle +11 more
2017JCI Insight18 citations Open access
Semantic Scholar
Primate resident memory T cells activate humoral and stromal immunity
V. Joag, B. Bimber, Clare F. Quarnstrom, V. S. Bollimpelli +27 more
2025Immunity16 citations Open access
Semantic Scholar
Distinct myeloid antigen-presenting cells dictate differential fates of tumor-specific CD8+ T cells in pancreatic cancer
A. Burrack, Zoe C. Schmiechen, Michael T. Patterson, Ebony A. Miller +7 more
2022JCI Insight16 citations Open access
Semantic Scholar
Fractionated radiotherapy combined with PD-1 pathway blockade promotes CD8 T cell-mediated tumor clearance for the treatment of advanced malignancies.
Tijana Martinov, B. Fife
2016Annals of Translational Medicine15 citations
Semantic Scholar
The role of programmed death-1 in type 1 diabetes
C. Tucker, Alexander J. Dwyer, B. Fife, Tijana Martinov
2021Current Diabetes Reports14 citations Open access
Semantic Scholar
Insulin B peptide-MHC class II-specific chimeric antigen receptor-Tregs prevent autoimmune diabetes
Justin A. Spanier, Vivian C. W. Fung, Christine M. Wardell, Mohannad H. Alkhatib +11 more
2023bioRxiv13 citations Open access
Semantic Scholar
Enhanced CD4+ and CD8+ T cell infiltrate within convex hull defined pancreatic islet borders as autoimmune diabetes progresses
Alexander J. Dwyer, Jacob M. Ritz, Jason S. Mitchell, Tijana Martinov +4 more
2021Scientific Reports13 citations Open access
Semantic Scholar
MULTI-STAGE T CELL-DENDRITIC CELL INTERACTIONS CONTROL OPTIMAL CD4 T CELL ACTIVATION THROUGH THE ADAP-SKAP55 SIGNALING MODULE
Jason S. Mitchell, B. Burbach, Rupa Srivastava, B. Fife +1 more
2013Journal of Immunology13 citations Open access
Semantic Scholar
Antigen-specific T cell responses in autoimmune diabetes
Alexander J. Dwyer, Zachary R. Shaheen, B. Fife
2024Frontiers in Immunology12 citations Open access
Semantic Scholar
Evaluating the Immunopathogenesis of Diabetes Following Acute Pancreatitis in the Diabetes RElated to Acute Pancreatitis and Its Mechanisms (DREAM) Study: From the Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC)
Anna Casu, P. Grippo, C. Wasserfall, Zhao-Li Sun +12 more
2022Pancreas11 citations Open access
Semantic Scholar
Tetrahydrocannabinol Reduces Hapten-Driven Mast Cell Accumulation and Persistent Tactile Sensitivity in Mouse Model of Allergen-Provoked Localized Vulvodynia
Beebie Boo, Charunayan Kamath, Erica Arriaga-Gomez, Jasmine Landry +6 more
2019International Journal of Molecular Sciences11 citations Open access
Semantic Scholar

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Justin A. Spanier×17
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