Researcher profile · Semantic Scholar

Xiaotian Yuan

h-index: 18
Works: 34
Citations: 1,332

Most-cited papers

Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new players
Xiaotian Yuan, C. Larsson, Dawei Xu
2019Oncogene391 citations Open access
Semantic Scholar
Cancer-Specific Telomerase Reverse Transcriptase (TERT) Promoter Mutations: Biological and Clinical Implications
Tian-Tian Liu, Xiaotian Yuan, Dawei Xu
2016Genes139 citations Open access
Semantic Scholar
TERT promoter mutations are associated with distant metastases in upper tract urothelial carcinomas and serve as urinary biomarkers detected by a sensitive castPCR
Kun Wang, Tian-Tian Liu, Nan Ge, Li Liu +13 more
2014OncoTarget66 citations Open access
Semantic Scholar
Telomere-related Markers for Cancer
Xiaotian Yuan, M. Dai, Dawei Xu
2020Current Topics in Medicinal Chemistry63 citations Open access
Semantic Scholar
Telomerase Reverse Transcriptase (TERT) in Action: Cross-Talking with Epigenetics
Xiaotian Yuan, Dawei Xu
2019International Journal of Molecular Sciences62 citations Open access
Semantic Scholar
GABPA inhibits invasion/metastasis in papillary thyroid carcinoma by regulating DICER1 expression
Xiaotian Yuan, Ninni Mu, Na Wang, K. Strååt +13 more
2018Oncogene56 citations
Semantic Scholar
Telomerase reverse transcriptase regulates DNMT3B expression/aberrant DNA methylation phenotype and AKT activation in hepatocellular carcinoma.
Jingya Yu, Xiaotian Yuan, Louise K. Sjöholm, Tian-Tian Liu +4 more
2018Cancer Letters53 citations
Semantic Scholar
GABPA is a master regulator of luminal identity and restrains aggressive diseases in bladder cancer
Yanxia Guo, Xiaotian Yuan, Kai-Lin Li, M. Dai +11 more
2019Cell Death and Differentiation48 citations Open access
Semantic Scholar
TERT promoter mutations and GABP transcription factors in carcinogenesis: More foes than friends.
Xiaotian Yuan, M. Dai, Dawei Xu
2020Cancer Letters46 citations Open access
Semantic Scholar
FKBP4 integrates FKBP4/Hsp90/IKK with FKBP4/Hsp70/RelA complex to promote lung adenocarcinoma progression via IKK/NF-κB signaling
Shuai Zong, Yulian Jiao, Xin Liu, Wenli Mu +10 more
2021Cell Death and Disease43 citations Open access
Semantic Scholar
The TERT promoter mutation incidence is modified by germline TERT rs2736098 and rs2736100 polymorphisms in hepatocellular carcinoma
Xiaotian Yuan, G. Cheng, Jingya Yu, Shun-Zhen Zheng +10 more
2017OncoTarget36 citations Open access
Semantic Scholar
TERT promoter mutations and TERT mRNA but not FGFR3 mutations are urinary biomarkers in Han Chinese patients with urothelial bladder cancer.
Kun Wang, Tian-Tian Liu, Cheng Liu, Y. Meng +11 more
2015The Oncologist35 citations Open access
Semantic Scholar
TERT rs2736100 genotypes are associated with differential risk of myeloproliferative neoplasms in Swedish and Chinese male patient populations
J. Dahlström, Tian-Tian Liu, Xiaotian Yuan, L. Saft +7 more
2016Annals of Hematology29 citations Open access
Semantic Scholar
GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma
Zhi-Qing Fang, Ning Zhang, Xiaotian Yuan, Xiangling Xing +9 more
2022Journal of experimental & clinical cancer research : CR27 citations Open access
Semantic Scholar
Longitudinal changes in leukocyte telomere length and mortality in elderly Swedish men
Xiaotian Yuan, Magnus Kronström, M. Hellénius, T. Cederholm +2 more
2018Aging27 citations Open access
Semantic Scholar
Histone Chaperone ASF1A Predicts Poor Outcomes for Patients With Gastrointestinal Cancer and Drives Cancer Progression by Stimulating Transcription of β-Catenin Target Genes
Xiuming Liang, Xiaotian Yuan, Jingya Yu, Yujiao Wu +8 more
2017EBioMedicine27 citations Open access
Semantic Scholar
The genetic difference between Western and Chinese urothelial cell carcinomas: infrequent FGFR3 mutation in Han Chinese patients
Xiaotian Yuan, Cheng Liu, Kun Wang, Li Liu +8 more
2016OncoTarget25 citations Open access
Semantic Scholar
PLEKHS1 Over-Expression is Associated with Metastases and Poor Outcomes in Papillary Thyroid Carcinoma
Xiangling Xing, Ninni Mu, Xiaotian Yuan, Na Wang +4 more
2020Cancers21 citations Open access
Semantic Scholar
Human 15‐lipoxygenase‐1 is a regulator of dendriticcell spreading and podosome formation
Hongya Han, Xiuming Liang, M. Ekberg, J. Kritikou +14 more
2017The FASEB Journal18 citations Open access
Semantic Scholar
The association between the TERT rs2736100 AC genotype and reduced risk of upper tract urothelial carcinomas in a Han Chinese population
Xiaotian Yuan, Y. Meng, Ping Li, Nan Ge +5 more
2016OncoTarget18 citations Open access
Semantic Scholar
Improvements and challenges of tissue preparation for spatial transcriptome analysis of skull base tumors
Yan Fang, Zhou-Ying Peng, Yu-Min Wang, Xiaotian Yuan +7 more
2023Heliyon17 citations Open access
Semantic Scholar
The TERT locus genotypes of rs2736100-CC/CA and rs2736098-AA predict shorter survival in renal cell carcinoma.
R. Ma, Cheng Liu, Min Lu, Xiaotian Yuan +7 more
2019Urologic oncology16 citations
Semantic Scholar
Regulatory region mutations of TERT, PLEKHS1 and GPR126 genes as urinary biomarkers in upper tract urothelial carcinomas
Xiangling Xing, Xiaotian Yuan, Tian-Tian Liu, M. Dai +5 more
2021Journal of Cancer14 citations Open access
Semantic Scholar
Telomerase reverse transcriptase promoter mutations in thyroid carcinomas: implications in precision oncology—a narrative review
Xiaotian Yuan, Tian-Tian Liu, Dawei Xu
2020Annals of Translational Medicine14 citations Open access
Semantic Scholar
Thyroid carcinoma‐featured telomerase activation and telomere maintenance: Biology and translational/clinical significance
Xiaotian Yuan, Huiyang Yuan, Ning Zhang, Tian-Tian Liu +1 more
2022Clinical and Translational Medicine13 citations Open access
Semantic Scholar
Association Between the Telomerase rs2736098_TT Genotype and a Lower Risk of Chronic Hepatitis B and Cirrhosis in Chinese Males
G. Cheng, Xiaotian Yuan, Fang Wang, Qing Sun +9 more
2017Clinical and Translational Gastroenterology10 citations Open access
Semantic Scholar
Downregulation and Hypermethylation of GABPB1 Is Associated with Aggressive Thyroid Cancer Features
Xiangling Xing, Ninni Mu, Xiaotian Yuan, Na Wang +5 more
2022Cancers8 citations Open access
Semantic Scholar
Clinical characteristics and prognostic factors of patients with non-small cell lung cancer having HER2 alterations
Xiaoli Zhuo, Honglin Guo, Jun Ma, J. Lai +9 more
2022Journal of Cancer Research and Clinical Oncology6 citations Open access
Semantic Scholar
JAK2 inhibition in JAK2V617F-bearing leukemia cells enriches CD34+ leukemic stem cells that are abolished by the telomerase inhibitor GRN163L.
J. Dahlström, Chuanyou Xia, Xiangling Xing, Xiaotian Yuan +2 more
2020Biochemical and Biophysical Research Communications - BBRC5 citations
Semantic Scholar
The ETS transcription factor GABPA inhibits bladder cancer aggressiveness by repressing extracellular matrix deposition and mechanotransduction signaling
M. Dai, Xiaotian Yuan, Chenxi Sun, Runyuan Han +4 more
2025Cell Death and Disease3 citations Open access
Semantic Scholar
Human 15-lipoxygenase-1 is a regulator of dendritic-cell spreading and podosome formation Human 15-lipoxygenase-1 is a regulator of dendritic-cell spreading and podosome formation.
Hongya Han, Xiuming Liang, M. Ekberg, J. Kritikou +14 more
20161 citations
Semantic Scholar
GABPA is a master regulator of luminal identity and restrains aggressive diseases in bladder cancer
Yanxia Guo, Xiaotian Yuan, Kai-Lin Li, M. Dai +11 more
2019Cell Death and Differentiation0 citations Open access
Semantic Scholar
The role of telomerase reverse transcriptase in human malignancies : genetic polymorphisms and promoter mutations
Xiaotian Yuan
20170 citations
Semantic Scholar
Abstract 3109: The TERT variant rs2736100_AC is associated with reduced risk of upper track urothelial carcinomas
Xiaotian Yuan, Ping Li, M. Björkholm, Dawei Xu
20160 citations
Semantic Scholar

Cheng Liu

×7

K. Strååt×7

M. Dai×6

Kai-Lin Li×6

G. Cheng×6

Ping Li×6

Yi-Dong Fan×5

Sheng-Tian Zhao×5