V. Avlani

Most-cited papers

1. Critical Role for the Second Extracellular Loop in the Binding of Both Orthosteric and Allosteric G Protein-coupled Receptor Ligands*

   V. Avlani, K. Gregory, C. Morton, M. Parker +2 more

   2007Journal of Biological Chemistry151 citations Open access

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2. Structure-Function Studies of Allosteric Agonism at M2 Muscarinic Acetylcholine Receptors

   Lauren T. May, V. Avlani, C. Langmead, H. Herdon +3 more

   2007Molecular Pharmacology111 citations

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3. Allosteric modulation of the calcium-sensing receptor by gamma-glutamyl peptides: inhibition of PTH secretion, suppression of intracellular cAMP levels, and a common mechanism of action with L-amino acids.

   G. Broadhead, Hee‐chang Mun, V. Avlani, Orane Jourdon +4 more

   2011Journal of Biological Chemistry89 citations Open access

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4. Orthosteric and Allosteric Modes of Interaction of Novel Selective Agonists of the M1 Muscarinic Acetylcholine Receptor

   V. Avlani, C. Langmead, E. Guida, M. Wood +5 more

   2010Molecular Pharmacology76 citations

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5. Allosteric modulation of G protein-coupled receptors.

   Lauren T. May, V. Avlani, P. Sexton, A. Christopoulos

   2004Current pharmaceutical design60 citations

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6. G-protein-coupled receptor allosterism: the promise and the problem(s).

   A. Christopoulos, Lauren T. May, V. Avlani, P. Sexton

   2004Biochemical Society Transactions60 citations

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7. Application of a Kinetic Model to the Apparently Complex Behavior of Negative and Positive Allosteric Modulators of Muscarinic Acetylcholine Receptors

   V. Avlani, Lauren T. May, P. Sexton, A. Christopoulos

   2004Journal of Pharmacology and Experimental Therapeutics53 citations

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8. Calcium-sensing receptor-dependent activation of CREB phosphorylation in HEK293 cells and human parathyroid cells.

   V. Avlani, Wen-Ting Ma, Hee‐chang Mun, K. Leach +3 more

   2013American Journal of Physiology. Endocrinology and Metabolism31 citations

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9. Structure-Function Studies of Allosteric Agonism at M 2 Muscarinic Acetylcholine Receptors

   Lauren T. May, V. Avlani, C. Langmead, H. Herdon +3 more

   200726 citations

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10. Allosteric Modulation of the Calcium-sensing Receptor by γ-Glutamyl Peptides

    G. Broadhead, Hee‐chang Mun, V. Avlani, Orane Jourdon +4 more

    2010Journal of Biological Chemistry17 citations Open access

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11. The Impact of Orthosteric Radioligand Depletion on the Quantification of Allosteric Modulator Interactions

    V. Avlani, David J. McLoughlin, P. Sexton, A. Christopoulos

    2008Journal of Pharmacology and Experimental Therapeutics11 citations

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12. Modulation of cAMP and cAMP-sensitive signaling by the calcium-sensing receptor

    A. Conigrave, V. Avlani, A. Christopoulos, Hee‐chang Mun

    20122 citations

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