P. D. den Besten

Most-cited papers

1. Tenax extraction mimics benthic and terrestrial bioavailability of organic compounds

   T. T. ten Hulscher, J. Postma, P. D. den Besten, Gerard J. Stroomberg +6 more

   2003Environmental Toxicology and Chemistry129 citations Open access

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2. Environmental impact and recovery at two dumping sites for dredged material in the North Sea.

   J. Stronkhorst, F. Ariese, B. V. van Hattum, J. Postma +6 more

   2003Environmental Pollution112 citations Open access

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3. A Weight-of-Evidence Framework for Assessing Sediment (Or Other) Contamination: Improving Certainty in the Decision-Making Process

   G. Burton, G. Batley, P. Chapman, V. Forbes +7 more

   2002110 citations

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4. Biological effects-based sediment quality in ecological risk assessment for European waters

   P. D. den Besten, E. de Deckere, Marc P. Babut, B. Power +4 more

   2003107 citations

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5. Principal response curves technique for the analysis of multivariate biomonitoring time series

   P. J. van den Brink, P. D. den Besten, Abraham Bij de Vaate, C. T. ter Braak

   2009Environmental Monitoring & Assessment99 citations Open access

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6. In Situ–Based Effects Measures: Considerations for Improving Methods and Approaches

   K. Liber, W. Goodfellow, P. D. den Besten, W. Clements +4 more

   2007Integrated Environmental Assessment and Management65 citations

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7. Bioaccumulation and biomarkers in the sea star Asterias rubens (Echinodermata: Asteroidea): a North Sea field study.

   P. D. den Besten, S. Valk, E. V. van Weerlee, R. Nolting +2 more

   2001Marine Environmental Research64 citations

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8. Evaluation of bioassays versus contaminant concentrations in explaining the macroinvertebrate community structure in the Rhine‐Meuse delta, The Netherlands

   E. T. Peeters, A. Dewitte, A. Koelmans, J. A. van der Velden +1 more

   2001Environmental Toxicology and Chemistry60 citations Open access

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9. Concepts for the implementation of biomarkers in environmental monitoring

   P. D. den Besten

   199860 citations

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10. Effects of cadmium and PCBs on reproduction of the sea star Asterias rubens: aberrations in the early development.

    P. D. den Besten, H. Herwig, D. Zandee, P. Voogt

    1989Ecotoxicology and Environmental Safety56 citations

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11. Sediment quality assessment in the delta of rivers Rhine and Meuse based on field observations, bioassays and food chain implications

    P. D. den Besten, C. Schmidt, M. Ohm, M. Ruys +2 more

    199552 citations

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12. Time-course and dose-response of the apparent induction of the cytochrome P450 monooxygenase system of pyloric caeca musomes of the female sea star Asterias rubens L. by benzo[a]pyrene and polychlorinated biphenyls

    P. D. den Besten, P. Lemaire, D. Livingstone, B. Woodin +3 more

    199351 citations

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13. Effects of cadmium and polychlorinated biphenyls (Clophen A50) on steroid metabolism and cytochrome P-450 monooxygenase system in the sea star Asterias rubens L

    P. D. den Besten, J. Elenbaas, J. Maas, S. Dieleman +2 more

    199151 citations

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14. Cytochrome P450 monooxygenase system in echinoderms.

    P. D. den Besten

    1998Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology48 citations

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15. Cytochrome P-450 monooxygenase system and benzo(a)pyrene metabolism in echinoderms

    P. D. den Besten, H. Herwig, E. V. van Donselaar, David R. Livingstone

    199046 citations

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16. DNA strand breaks, cytochrome P-450-dependent monooxygenase system activity and levels of chlorinated biphenyl congeners in the pyloric caeca of the seastar (Asterias rubens) from the North Sea

    J. Everaarts, P. D. den Besten, M. Hillebrand, R. Halbrook +1 more

    199844 citations

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17. Sediment pollution and predation affect structure and production of benthic macroinvertebrate communities in the Rhine–Meuse delta, The Netherlands

    H. D. de Lange, J. de Jonge, P. D. den Besten, J. Oosterbaan +1 more

    2004Journal of The North American Benthological Society43 citations Open access

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18. Effects of cadmium and zinc on steroid metabolism and steroid level in the sea star Asterias rubens L.

    P. Voogt, P. D. den Besten, G. C. Kusters, M. Messing

    1987Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology41 citations Open access

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19. Ecotoxicological testing of marine and freshwater ecosystems: Emerging techniques, trends and strategies

    P. D. den Besten, M. Munawar, G. Suter

    200539 citations

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20. Molecular responses as indicators of marine pollution: DNA damage and enzyme induction in Limanda limanda and Asterias rubens.

    J. Everaarts, H. M. Sleiderink, P. D. den Besten, R. Halbrook +1 more

    1994Environmental Health Perspectives35 citations Open access

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21. Steroid metabolism in relation to the reproductive cycle in Asterias rubens L.

    P. Voogt, P. D. den Besten, M. Jansen

    199132 citations

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22. The △5-pathway in steroid metabolism in the sea star Asterias rubens l.

    P. Voogt, P. D. den Besten, M. Jansen

    199029 citations

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23. An Overview of the Partitioning and Bioavailability of PAHs in Sediments and Soils

    R. M. Burgess, M. Ahrens, C. Hickey, P. D. den Besten +4 more

    200328 citations

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24. Cadmium accumulation and metallothionein-like proteins in the sea starAsterias rubens

    P. D. den Besten, H. Herwig, D. Zandee, P. Voogt

    199028 citations

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25. In situ Bioassays with Chironomus riparius : Laboratory-Field Comparisons of Sediment Toxicity and Effects During Wintering

    P. D. den Besten, A. Naber, E. M. Grootelaar, C. van de Guchte

    200327 citations

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26. Interference of polychlorinated biphenyls (Clophen A50) with gametogenesis in the sea star, Asterias rubens L.

    P. D. den Besten, H. Herwig, A. C. Smaal, D. Zandee +1 more

    199023 citations

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27. In vivo exposure of Dreissena polymorpha mussels to the quinones menadione and lawsone: menadione is more toxic to mussels than lawsone

    A. Osman, S. Rotteveel, P. D. den Besten, P. V. van Noort

    2004Journal of Applied Toxicology22 citations

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28. Effects of cadmium on metal composition and adenylate energy charge in the sea starAsterias rubens L

    P. D. den Besten, P. Bosma, H. Herwig, D. Zandee +1 more

    1991Archives of Environmental Contamination and Toxicology21 citations

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29. Risk assessment approaches in European countries

    P. D. den Besten

    200719 citations

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30. Relation between responses in the neutral red retention test and the comet assay and life history parameters of Daphnia magna.

    P. D. den Besten, C. Tuk

    2000Marine Environmental Research18 citations

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31. Effects of cadmium on gametogenesis in the sea star Asterias rubensL.

    P. D. den Besten, E. V. van Donselaar, H. Herwig, D. Zandee +1 more

    199118 citations

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32. Interference of benzo[a]pyrene with cytochrome P-450-mediated steroid metabolism in pyloric caeca microsomes of the sea star Asterias rubens L.

    P. D. den Besten, J. Maas, D. Livingstone, D. Zandee +1 more

    199117 citations

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33. Parathymic lymph nodes during growth and rejection of intraperitoneally inoculated tumor cells.

    H. Dullens, L. H. Rademakers, S. Cluistra, R. V. van Os +3 more

    1991Invasion and Metastasis17 citations

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34. Bioavailability, Uptake and Effects of PAHs in Aquatic Invertebrates in Field Studies

    P. D. den Besten, D. T. ten Hulscher, A. G. M. van Hattum

    200316 citations

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35. Biological markers of environmental contamination in marine ecosystems: BIOMAR project

    J. Narbonne, P. Mora, X. Michel, H. Budzinski +10 more

    199915 citations

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36. Cadmium accumulation and metallothionein-like proteins in the Sea star Asterias rubens

    P. D. den Besten, H. Herwig, D. Zandee, P. Voogt

    198915 citations

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37. Production of specific macrophage-arming factor precedes cytotoxic T lymphocyte activity in vivo during tumor rejection

    H. Dullens, R. D. de Weger, M. van der Maas, P. D. den Besten +2 more

    2005Cancer Immunology and Immunotherapy11 citations Open access

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38. Bioassays and tiered approaches for monitoring surface water quality and effluents

    P. D. den Besten, D. Leverett, M. Tonkes

    200510 citations

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39. Menadione enhances oxyradical formation in earthworm extracts: vulnerability of earthworms to quinone toxicity.

    A. Osman, P. D. den Besten, P. V. van Noort

    2003Aquatic Toxicology10 citations

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40. Use of Sediment Quality Guidelines in Ecological Risk Assessment of Dredged Materials: Preliminary Reflections

    Marc Babut, J. Garric, M. Camusso, P. D. den Besten

    200310 citations

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41. NADPH-, NADH- and cumene hydroperoxide-dependent metabolism of benzo[a]pyrene by pyloric caeca microsomes of the sea star Asterias rubens L. (Echinodermata: Asteroidea).

    P. D. den Besten, P. Lemaire, D. Livingstone

    1994Xenobiotica; the fate of foreign compounds in biological systems10 citations

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42. Bioassay responses and effects on benthos after pilot remediations in the delta of the rivers Rhine and Meuse.

    P. D. den Besten, P. J. van den Brink

    20059 citations Open access

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43. Biological and chemical monitoring after pilot remediations in the delta of the rivers Rhine and Meuse

    P. D. den Besten, J. Postma, J. Wegener, H. Keidel +3 more

    20009 citations Open access

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44. Biological Markers of Environmental Contamination in Marine Ecosystems

    J. Narbonne, P. Mora, X. Michel, H. Budzinski +10 more

    19999 citations

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45. Statistical analysis of sediment toxicity by additive monotone regression splines.

    W. D. de Boer, P. D. den Besten, C. T. ter Braak

    20027 citations Open access

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46. Further characterization of benzo[a]pyrene metabolism in the sea star, Asterias rubens L

    P. D. den Besten, S. O'Hara, D. Livingstone

    19927 citations

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47. Mixed-function oxygenase system and benzo[a]pyrene metabolism in echinoderms

    P. D. den Besten, D. Livingstone

    19897 citations

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48. Bioassay responses and effects on benthos after pilot remediations in the delta of the rivers Rhine and Meuse.

    P. D. den Besten, P. J. van den Brink

    2005Environmental Pollution6 citations

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49. Synthesis of the sednet work package 5 outcomes

    S. Heise, S. Apitz, M. Babut, H. Bergmann +8 more

    20046 citations

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50. Cytochrome P 450 monooxygenase system in echinoderms 1

    P. D. den Besten

    19985 citations

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