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U. Giri · SciRah

Researcher profile · Semantic Scholar

U. Giri

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U. Giri — researcher profile on SciRah

h-index: 25
Works: 94
Citations: 4,628

Most-cited papers

An epithelial-mesenchymal transition (EMT) gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance
L. Byers, L. Diao, Jing Wang, P. Saintigny +30 more
2012Clinical Cancer Research950 citations Open access
Semantic Scholar
Co-occurring genomic alterations define major subsets of KRAS - mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities
F. Skoulidis, L. Byers, L. Diao, V. Papadimitrakopoulou +33 more
2015Cancer Discovery867 citations Open access
Semantic Scholar
Proteomic Profiling Identifies Dysregulated Pathways in Small Cell Lung Cancer and Novel Therapeutic Targets Including PARP1
L. Byers, Jing Wang, M. Nilsson, J. Fujimoto +24 more
2012Cancer Discovery504 citations Open access
Semantic Scholar
Detection of T790M, the acquired resistance EGFR mutation, by tumor biopsy versus noninvasive blood-based analyses
T. Sundaresan, L. Sequist, J. Heymach, Gregory Riely +21 more
2015Clinical Cancer Research346 citations Open access
Semantic Scholar
TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence
H. Skinner, V. Sandulache, T. Ow, R. Meyn +6 more
2011Clinical Cancer Research287 citations Open access
Semantic Scholar
KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling.
K. Wagner, Hunain Alam, S. Dhar, U. Giri +16 more
2013Journal of Clinical Investigation170 citations Open access
Semantic Scholar
Evolutionary Action score of TP53 (EAp53) identifies high risk mutations associated with decreased survival and increased distant metastases in head and neck cancer
David M. Neskey, A. Osman, T. Ow, Panagiotis Katsonis +20 more
2015Cancer Research156 citations Open access
Semantic Scholar
miRNA expression profiles in head and neck squamous cell carcinoma and adjacent normal tissue
L. Ramdas, U. Giri, Cheryl L. Ashorn, K. Coombes +3 more
2009Head and Neck154 citations Open access
Semantic Scholar
Integrative analysis identifies a novel AXL-PI3 kinase-PD-L1 signaling axis associated with radiation resistance in head and neck cancer
H. Skinner, U. Giri, Liang-Peng Yang, Manish Kumar +14 more
2017Clinical Cancer Research99 citations Open access
Semantic Scholar
DNA Repair Biomarker Profiling of Head & Neck Cancer: Ku80 Expression Predicts Locoregional Failure and Death Following Radiotherapy
B. Moeller, J. Yordy, Michelle D. Williams, U. Giri +11 more
2011Clinical Cancer Research94 citations Open access
Semantic Scholar
Evidence that in situ generated reactive oxygen species act as a potent stage I tumor promoter in mouse skin.
U. Giri, S. Sharma, M. Abdulla, M. Athar
1995Biochemical and Biophysical Research Communications - BBRC76 citations
Semantic Scholar
LKB1 mutations in NSCLC are associated with KEAP1/NRF2-dependent radiotherapy resistance targetable by glutaminase inhibition
P. Sitthideatphaiboon, Ana Galán-Cobo, M. Negrao, Xiao Qu +13 more
2020Clinical Cancer Research74 citations Open access
Semantic Scholar
In Vivo Delivery of miR-34a Sensitizes Lung Tumors to Radiation Through RAD51 Regulation
M. Cortez, D. Valdecanas, S. Niknam, Heidi J. Peltier +9 more
2015Molecular Therapy: Nucleic Acids74 citations Open access
Semantic Scholar
The HGF/c-MET pathway is a driver and biomarker of VEGFR-inhibitor resistance and vascular remodeling in non-small cell lung cancer
T. Cascone, Li Xu, Heather Y. Lin, Wen-Bin Liu +21 more
2017Clinical Cancer Research68 citations Open access
Semantic Scholar
Proteomic profiling identifies PTK2/FAK as a driver of radioresistance in HPV-negative head and neck cancer
H. Skinner, U. Giri, Liang-Peng Yang, S. Woo +14 more
2016Clinical Cancer Research67 citations Open access
Semantic Scholar
Increased VEGFR-2 Gene Copy Is Associated With Chemoresistance and Shorter Survival in Patients with Non-small Cell Lung Carcinoma Who Receive Adjuvant Chemotherapy
Fei Yang, Xi-Ming Tang, E. Riquelme, C. Behrens +14 more
2011Cancer Research66 citations Open access
Semantic Scholar
A novel Chk inhibitor, XL-844, increases human cancer cell radiosensitivity through promotion of mitotic catastrophe
O. Riesterer, F. Matsumoto, Li Wang, J. Pickett +4 more
2011Investigational new drugs57 citations Open access
Semantic Scholar
Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial–mesenchymal transition
S. Lin, Jing Wang, P. Saintigny, Chia-Chin Wu +13 more
2014BMC Genomics50 citations Open access
Semantic Scholar
miR-125a-5p Functions as Tumor Suppressor microRNA And Is a Marker of Locoregional Recurrence And Poor prognosis in Head And Neck Cancer
D. Vo, N. K. Karanam, L. Ding, D. Saha +4 more
2019Neoplasia46 citations Open access
Semantic Scholar
Epithelial-Mesenchymal Transition Predicts Polo-Like Kinase 1 Inhibitor-Mediated Apoptosis in Non-Small Cell Lung Cancer
R. Ferrarotto, Ruchitha Goonatilake, S. Yoo, P. Tong +15 more
2015Clinical Cancer Research45 citations Open access
Semantic Scholar
A High Content Clonogenic Survival Drug Screen Identifies MEK Inhibitors as Potent Radiation Sensitizers for KRAS Mutant Non-Small Cell Lung Cancer
S. Lin, Jing Zhang, U. Giri, C. Stephan +7 more
2014Journal of Thoracic Oncology39 citations Open access
Semantic Scholar
RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non–small Cell Lung Cancer
Yifan Wang, J. Gudikote, U. Giri, Jun-Hai Yan +12 more
2017Clinical Cancer Research36 citations Open access
Semantic Scholar
Dasatinib induces DNA damage and activates DNA repair pathways leading to senescence in non-small cell lung cancer cell lines with kinase-inactivating BRAF mutations
S. Peng, B. Sen, T. Mazumdar, L. Byers +7 more
2015OncoTarget36 citations Open access
Semantic Scholar
Molecular signatures associated with clinical outcome in patients with high-risk head-and-neck squamous cell carcinoma treated by surgery and radiation.
U. Giri, Cheryl L. Ashorn, L. Ramdas, David N. Stivers +4 more
2006International Journal of Radiation Oncology, Biology, Physics33 citations
Semantic Scholar
Comparison of single, fractionated and hyperfractionated irradiation on the development of normal tissue damage in rat lung.
P. G. Shankar Giri, B. Kimler, U. Giri, Gail G. Cox +1 more
1985International Journal of Radiation Oncology, Biology, Physics29 citations
Semantic Scholar
An epithelial-mesenchymal transition ( EMT ) gene signature predicts resistance to EGFR and PI 3 K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance
L. Byers, L. Diao, Jing Wang, P. Saintigny +35 more
201226 citations
Semantic Scholar
Polo-like kinase 1 inhibition diminishes acquired resistance to epidermal growth factor receptor inhibition in non-small cell lung cancer with T790M mutations
Yue-Hong Wang, Ratnakar Singh, Li-Guang Wang, M. Nilsson +11 more
2016OncoTarget25 citations Open access
Semantic Scholar
Population-level comparisons of gene regulatory networks modeled on high-throughput single-cell transcriptomics data
Daniel Osório, A. Capasso, S. Eckhardt, U. Giri +10 more
2023bioRxiv21 citations Open access
Semantic Scholar
8-Chloroadenosine Sensitivity in Renal Cell Carcinoma Is Associated with AMPK Activation and mTOR Pathway Inhibition
Alper Y. Kearney, You-Hong Fan, U. Giri, B. Saigal +3 more
2015PLoS ONE19 citations Open access
Semantic Scholar
Evidence that Fe‐NTA‐induced renal prostaglandin F2α is responsible for hyperplastic response in kidney: Implications for the role of cyclooxygenase‐dependent arachidonic acid metabolism in renal tumor promotion
M. Iqbal, U. Giri, Dipak K. Giri, M. Athar
199719 citations
Semantic Scholar
Covalent JNK inhibitor, JNK-IN-8, suppresses tumor growth in triple-negative breast cancer by activating TFEB and TFE3 mediated lysosome biogenesis and autophagy.
Milad Soleimani, Alex Somma, Tamer S. Kaoud, Ria Goyal +10 more
2022Molecular Cancer Therapeutics18 citations Open access
Semantic Scholar
KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib
M. Nilsson, U. Giri, J. Gudikote, Xi-Ming Tang +14 more
2015Clinical Cancer Research15 citations Open access
Semantic Scholar
Elimination of the differential chemoresistance between the murine B-cell lymphoma LY-ar and LY-as cell lines after arsenic (As2O3) exposure via the overexpression of gsto1 (p28)
U. Giri, N. Terry, S. V. Kala, M. Lieberman +1 more
2005Cancer Chemotherapy and Pharmacology9 citations
Semantic Scholar
Enhanced vulnerability of LKB1-deficient NSCLC to disruption of ATP pools and redox homeostasis by 8-Cl-Ado
Ana Galán-Cobo, C. Stellrecht, E. Yilmaz, Chao-Xu Yang +17 more
2021Molecular Cancer Research8 citations Open access
Semantic Scholar
Elucidating the direct effects of the novel HDAC inhibitor bocodepsin (OKI-179) on T cells to rationally design regimens for combining with immunotherapy
Nisha Holay, Alex Somma, M. Duchow, Milad Soleimani +10 more
2023Frontiers in Immunology5 citations Open access
Semantic Scholar
Sialochemical Profile in Depressive Individuals under Antidepressant Therapy: An Observational Study
U. Giri, Vezhavendhan Nagaraj, A. Sankaran, R. Ramesh +4 more
20185 citations Open access
Semantic Scholar
Human lymphoma cells develop resistance to radiation in the presence of astrocytes in vitro.
M. Koto, Heunglae Cho, O. Riesterer, U. Giri +3 more
2011Anticancer Research5 citations
Semantic Scholar
Hyperfractionation protects against long-term fibrosis in rat lung.
P. Giri, B. Kimler, U. Giri, Gail G. Cox
1986The British journal of cancer. Supplement5 citations
Semantic Scholar
Imexon augments sensitivity of human lymphoma cells to ionizing radiation: in vitro experimental study.
Heunglae Cho, M. Koto, O. Riesterer, D. Molkentine +5 more
2009Anticancer Research4 citations
Semantic Scholar
A Hospital Based Study of Association of Chronic Spontaneous Urticaria with Autologous Serum Skin Test
U. Giri, B. M. Kayastha, N. Shakya
20203 citations Open access
Semantic Scholar
An epithelial-mesenchymal transition (EMT) gene signature to predict resistance to EGFR inhibition and AXL identification as a therapeutic target in head and neck squamous cell carcinoma.
R. Cardnell, L. Diao, Jing Wang, D. Bearss +14 more
20133 citations
Semantic Scholar
High Throughput Clonogenic Survival Screen Identifies Novel Radiation Sensitizers for K-ras Mutant Non-Small Cell Lung Cancer
S. Lin, Jing Zhang, U. Giri, C. Stephan +6 more
20133 citations Open access
Semantic Scholar
Use of proteomic analysis of LKB1/AMPK/mTOR pathways to identify IGF-1R pathway upregulation with LKB1 loss or mTOR inhibition in NSCLC: Implications for targeted combinations.
E. Yilmaz, L. Byers, L. Diao, U. Giri +7 more
20123 citations
Semantic Scholar
Dermatomyositis in an Elderly with Respiratory Presentation: A Case Report
Srijana Maharjan, U. Giri, Anushree Jha, Roshan Rijal +2 more
2022JNMA; journal of the Nepal Medical Association2 citations Open access
Semantic Scholar
Potentiation of radiation-induced normal lung tissue damage in rats by cancer chemotherapeutic agents
B. Kimler, P. G. Shankar Giri, U. Giri, Gail G. Cox
19842 citations Open access
Semantic Scholar
Profile of Neurosyphilis Patients Admitted to a Tertiary Care Centre of Nepal: An Observational Study
U. Giri, Laila Lama Tangbetani, Anupama Karki, J. Ghimire
2025JNMA; journal of the Nepal Medical Association1 citations Open access
Semantic Scholar
Abstract 4109: Covalent JNK inhibitor, JNK-IN-8, suppresses tumor growth in triple-negative breast cancer in part by activating lysosome biogenesis and autophagy via TFEB and TFE3
Milad Soleimani, Tamer S. Kaoud, Alex Somma, Jorge Bustamante +9 more
2022Cancer Research1 citations
Semantic Scholar
Abstract 5648: Combined immune checkpoint targeting with anti-PD-1 plus anti-CD40 antibodies as the most effective approach to eradicate head and neck squamous cell carcinomas (HNSCCs) in mouse models
Jose Augusto Monteiro de Oliveira Novaes, A. Poteete, M. Pisegna, U. Giri +4 more
20171 citations
Semantic Scholar
The CDK4/6 inhibitor G1T28 to protect immune cells and fibroblasts from chemotherapy and radiation-induced toxicity in vitro and to maintain efficacy of chemotherapy in SCLC Rb-deficient cells.
I. Guijarro, W. Denning, R. Ferrarotto, A. Poteete +8 more
20161 citations
Semantic Scholar
Abstract 3998: miRNA associated with distal metastasis and local recurrence after post-operative radiotherapy in high-risk head and neck cancer
L. Ding, N. K. Karanam, J. Yordy, U. Giri +1 more
20151 citations
Semantic Scholar

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