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S. Ghisletti · SciRah

Researcher profile · Semantic Scholar

S. Ghisletti

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S. Ghisletti — researcher profile on SciRah

h-index: 29
Works: 57
Citations: 7,493

Most-cited papers

A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers
F. De Santa, I. Barozzi, F. Mietton, S. Ghisletti +6 more
2010PLoS Biology900 citations Open access
Semantic Scholar
Latent enhancers activated by stimulation in differentiated cells.
R. Ostuni, Viviana Piccolo, I. Barozzi, S. Polletti +6 more
2013Cell815 citations Open access
Semantic Scholar
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages.
S. Ghisletti, I. Barozzi, F. Mietton, S. Polletti +8 more
2010Immunity675 citations Open access
Semantic Scholar
Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor κB
C. Porta, M. Rimoldi, G. Raes, L. Brys +8 more
2009Proceedings of the National Academy of Sciences of the United States of America659 citations Open access
Semantic Scholar
Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma.
S. Ghisletti, W. Huang, S. Ogawa, G. Pascual +4 more
2007Molecules and Cells603 citations Open access
Semantic Scholar
Estrogen receptor-α mediates the brain antiinflammatory activity of estradiol
E. Vegeto, Silvia Belcredito, Sabrina Etteri, S. Ghisletti +7 more
2003Proceedings of the National Academy of Sciences of the United States of America401 citations Open access
Semantic Scholar
17β-Estradiol Inhibits Inflammatory Gene Expression by Controlling NF-κB Intracellular Localization
S. Ghisletti, Clara Meda, A. Maggi, E. Vegeto
2005Molecular and Cellular Biology380 citations Open access
Semantic Scholar
Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways.
S. Ghisletti, W. Huang, K. Jepsen, C. Benner +3 more
2009Genes & Development262 citations Open access
Semantic Scholar
Edinburgh Research Explorer Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma
R. Shukla, K. Upton, M. Muñoz-López, D. J. Gerhardt +13 more
240 citations
Semantic Scholar
Co-regulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers
I. Barozzi, M. Simonatto, S. Bonifacio, Lin Yang +3 more
2014Molecules and Cells212 citations Open access
Semantic Scholar
Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross talks
Viviana Piccolo, A. Curina, M. Genua, S. Ghisletti +5 more
2017Nature Immunology198 citations Open access
Semantic Scholar
17beta-estradiol inhibits inflammatory gene expression by controlling NF-kappaB intracellular localization.
S. Ghisletti, Clara Meda, A. Maggi, E. Vegeto
2005Molecular and Cellular Biology188 citations
Semantic Scholar
The endogenous estrogen status regulates microglia reactivity in animal models of neuroinflammation.
E. Vegeto, Silvia Belcredito, S. Ghisletti, Clara Meda +2 more
2006Endocrinology177 citations Open access
Semantic Scholar
Coronin2A mediates actin-dependent de-repression of inflammatory response genes
W. Huang, S. Ghisletti, K. Saijo, Meghal Gandhi +8 more
2011Nature166 citations Open access
Semantic Scholar
Mechanisms Establishing TLR4-Responsive Activation States of Inflammatory Response Genes
L. Escoubet-Lozach, C. Benner, M. Kaikkonen, J. Lozach +16 more
2011PLoS Genetics157 citations Open access
Semantic Scholar
The genomic landscapes of inflammation.
G. Natoli, S. Ghisletti, I. Barozzi
2011Genes & Development156 citations Open access
Semantic Scholar
Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma
R. Shukla, K. Upton, M. Muñoz-López, D. J. Gerhardt +19 more
2013Cell138 citations Open access
Semantic Scholar
A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages
A. Mancino, A. Termanini, I. Barozzi, S. Ghisletti +4 more
2015Genes & Development128 citations Open access
Semantic Scholar
Transcriptional integration of TLR2 and TLR4 signaling at the NCoR de-repression checkpoint
W. Huang, S. Ghisletti, Valentina Perissi, M. Rosenfeld +1 more
2009Molecules and Cells120 citations Open access
Semantic Scholar
Regulation of the lipopolysaccharide signal transduction pathway by 17beta-estradiol in macrophage cells.
E. Vegeto, S. Ghisletti, Clara Meda, Sabrina Etteri +2 more
2004Journal of Steroid Biochemistry and Molecular Biology119 citations
Semantic Scholar
Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination.
L. Austenaa, I. Barozzi, M. Simonatto, S. Masella +12 more
2015Molecules and Cells99 citations Open access
Semantic Scholar
L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis
S. N. Schauer, Patricia E. Carreira, R. Shukla, D. J. Gerhardt +12 more
2018Genome Research83 citations Open access
Semantic Scholar
CAGE profiling of ncRNAs in hepatocellular carcinoma reveals widespread activation of retroviral LTR promoters in virus-induced tumors
K. Hashimoto, A. Suzuki, A. Dos Santos, C. Desterke +15 more
2015Genome Research65 citations Open access
Semantic Scholar
Massive gene amplification drives paediatric hepatocellular carcinoma caused by bile salt export pump deficiency
F. Iannelli, Agnese Collino, Shruti Sinha, E. Radaelli +11 more
2014Nature Communications61 citations Open access
Semantic Scholar
High constitutive activity of a broad panel of housekeeping and tissue-specific cis-regulatory elements depends on a subset of ETS proteins
A. Curina, A. Termanini, I. Barozzi, Elena Prosperini +8 more
2017Genes & Development51 citations Open access
Semantic Scholar
A first exon termination checkpoint preferentially suppresses extragenic transcription
L. Austenaa, Viviana Piccolo, M. Russo, Elena Prosperini +6 more
2021Nature Structural & Molecular Biology50 citations Open access
Semantic Scholar
Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity.
E. Chao, Justin A. Caravella, M. Watson, N. Campobasso +18 more
2008Journal of Medicinal Chemistry49 citations Open access
Semantic Scholar
Estrogen neuroprotection: the involvement of the Bcl-2 binding protein BNIP2.
Silvia Belcredito, E. Vegeto, A. Brusadelli, S. Ghisletti +3 more
2001Brain research. Brain research reviews40 citations
Semantic Scholar
Zc3h10 is a novel mitochondrial regulator
M. Audano, S. Pedretti, G. Cermenati, E. Brioschi +17 more
2018EMBO Reports32 citations Open access
Semantic Scholar
Zc3h10 regulates adipogenesis by controlling translation and F-actin/mitochondria interaction
M. Audano, S. Pedretti, Simona Ligorio, Francesco Gualdrini +8 more
2021Journal of Cell Biology29 citations Open access
Semantic Scholar
Novel insights into the role of acetyl-CoA producing enzymes in epigenetic regulation
M. Russo, Francesco Pileri, S. Ghisletti
2023Frontiers in Endocrinology28 citations Open access
Semantic Scholar
Integration of transcriptional and metabolic control in macrophage activation
G. Natoli, Francesco Pileri, Francesco Gualdrini, S. Ghisletti
2021EMBO Reports27 citations Open access
Semantic Scholar
Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer
A. Cortesi, Francesco Gandolfi, Fabiana Arco, Pierluigi DiChiaro +19 more
2024Science Advances26 citations Open access
Semantic Scholar
Mutual epithelium‐macrophage dependency in liver carcinogenesis mediated by ST18
M. Ravà, A. D’Andrea, M. Doni, Theresia R. Kress +15 more
2016Hepatology23 citations Open access
Semantic Scholar
Estrogen receptor alpha, a molecular switch converting transforming growth factor-alpha-mediated proliferation into differentiation in neuroblastoma cells.
P. Ciana, S. Ghisletti, Paola Mussi, I. Eberini +2 more
2003Journal of Biological Chemistry23 citations
Semantic Scholar
Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide
M. Russo, Francesco Gualdrini, V. Vallelonga, Elena Prosperini +15 more
2024Molecules and Cells20 citations Open access
Semantic Scholar
Deciphering cis-regulatory control in inflammatory cells
S. Ghisletti, G. Natoli
2013Philosophical Transactions of the Royal Society B: Biological Sciences20 citations Open access
Semantic Scholar
D-lactate and glycerol as potential biomarkers of sorafenib activity in hepatocellular carcinoma
S. Pedretti, F. Palermo, Miriana Braghin, G. Imperato +13 more
2025Signal Transduction and Targeted Therapy19 citations Open access
Semantic Scholar
Characterization and Clinical Implications of p53 Dysfunction in Patients With Myelodysplastic Syndromes
M. Zampini, E. Riva, L. Lanino, E. Sauta +46 more
2025Journal of Clinical Oncology15 citations Open access
Semantic Scholar
TCA-cycle metabolites in the nucleus: drivers of chromatin and epigenetic control
S. Ghisletti, M. Russo
2025BMC Biology13 citations Open access
Semantic Scholar
Emerging Insights into Molecular Mechanisms of Inflammation in Myelodysplastic Syndromes
V. Vallelonga, Francesco Gandolfi, F. Ficara, M. D. della Porta +1 more
2023Biomedicines13 citations Open access
Semantic Scholar
Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage
Agnese Collino, A. Termanini, Paola Nicoli, G. Diaferia +7 more
2018PLoS Genetics12 citations Open access
Semantic Scholar
Housekeeping and tissue-specific cis-regulatory elements: Recipes for specificity and recipes for activity
M. Russo, G. Natoli, S. Ghisletti
2018Transcription7 citations Open access
Semantic Scholar
Amine‐modified poly(vinyl alcohol) as a novel surfactant to modulate size and surface charge of poly(lactide‐co‐glycolide) nanoparticles
C. Cella, F. Martello, S. Ghisletti, C. Lenardi +2 more
20164 citations
Semantic Scholar
Targeting ATP-Citrate Lyase Across Cardiometabolic and Oncologic Disease.
C. Macchi, S. Pedretti, S. Ghisletti, A. Corsini +3 more
2026Pharmacological Research2 citations Open access
Semantic Scholar
Correction: Corrigendum: Massive gene amplification drives paediatric hepatocellular carcinoma caused by bile salt export pump deficiency
F. Iannelli, Agnese Collino, Shruti Sinha, E. Radaelli +11 more
2015Nature Communications2 citations Open access
Semantic Scholar
Single-Cell Multi-Omics Reveals Anticipated Erythroid Differentiation and Transcriptional Regulation in Differentiation Trajectories of SF3B1 - JAK2/MPL Mutated Cells in MDS/MPN-RS-T
M. Zampini, G. Todisco, A. Chiodi, C. Chiereghin +21 more
2024Blood0 citations
Semantic Scholar
The Macrophage Epigenome and the Control of Inflammatory Gene Expression
S. Polletti, A. Curina, G. Natoli, S. Ghisletti
20140 citations
Semantic Scholar
Detection of Copy Number Variations from Targeted Re-sequencing data
Shruti Sinha, F. Iannelli, Agnese Collino, G. Natoli +2 more
20130 citations
Semantic Scholar
Macrophages (PP-047)
M. Kinoshita, T. Uchida, A. Sato, M. Nakashima +285 more
20100 citations Open access
Semantic Scholar

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