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G. Basañez · SciRah

Researcher profile · Semantic Scholar

G. Basañez

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G. Basañez — researcher profile on SciRah

h-index: 36
Works: 58
Citations: 5,609

Most-cited papers

Calpain I Induces Cleavage and Release of Apoptosis-inducing Factor from Isolated Mitochondria*
B. Polster, G. Basañez, A. Etxebarria, J. Hardwick +1 more
2005Journal of Biological Chemistry456 citations Open access
Semantic Scholar
Membrane Remodeling Induced by the Dynamin Related Protein Drp1 Stimulates Bax Oligomerization
S. Montessuit, S. Somasekharan, Oihana Terrones, Safa Lucken-Ardjomande +7 more
2010Cell453 citations Open access
Semantic Scholar
Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3
S. Tzung, Kristine M. Kim, G. Basañez, C. Giedt +4 more
2001Nature Cell Biology450 citations
Semantic Scholar
Mitochondrial fission proteins regulate programmed cell death in yeast.
Yihru Fannjiang, Wen-Chih Cheng, Sarah J. Lee, B. Qi +5 more
2004Genes & Development325 citations Open access
Semantic Scholar
Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations.
G. Basañez, A. Nechushtan, O. Drozhinin, A. Chanturiya +6 more
1999Proceedings of the National Academy of Sciences of the United States of America281 citations Open access
Semantic Scholar
Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma.
J. Montero, A. Morales, Laura Llacuna, J. Lluis +7 more
2008Cancer Research260 citations Open access
Semantic Scholar
Bax-type Apoptotic Proteins Porate Pure Lipid Bilayers through a Mechanism Sensitive to Intrinsic Monolayer Curvature*
G. Basañez, J. Sharpe, Jennifer Galanis, Teresa B. Brandt +2 more
2002Journal of Biological Chemistry249 citations Open access
Semantic Scholar
Lipidic Pore Formation by the Concerted Action of Proapoptotic BAX and tBID*
Oihana Terrones, B. Antonsson, H. Yamaguchi, Hong-Gang Wang +4 more
2004Journal of Biological Chemistry247 citations Open access
Semantic Scholar
Specific Interaction with Cardiolipin Triggers Functional Activation of Dynamin-Related Protein 1
Itsasne Bustillo-Zabalbeitia, S. Montessuit, Etienne Raemy, G. Basañez +2 more
2014PLoS ONE154 citations Open access
Semantic Scholar
Different Effects of Enzyme-generated Ceramides and Diacylglycerols in Phospholipid Membrane Fusion and Leakage*
M. Ruiz-Argüello, G. Basañez, Félix M. Goñi, A. Alonso
1996Journal of Biological Chemistry153 citations Open access
Semantic Scholar
Pro-apoptotic Cleavage Products of Bcl-xL Form Cytochrome c-conducting Pores in Pure Lipid Membranes*
G. Basañez, Jun Zhang, B. Chau, Grigory I. Maksaev +5 more
2001Journal of Biological Chemistry149 citations Open access
Semantic Scholar
Proapoptotic Bax and Bak Proteins Form Stable Protein-permeable Pores of Tunable Size
Stephanie Bleicken, Olatz Landeta, Ane Landajuela, G. Basañez +1 more
2013Journal of Biological Chemistry146 citations Open access
Semantic Scholar
PB1-F2, an Influenza A Virus-Encoded Proapoptotic Mitochondrial Protein, Creates Variably Sized Pores in Planar Lipid Membranes
A. Chanturiya, G. Basañez, U. Schubert, P. Henklein +2 more
2004Journal of Virology145 citations Open access
Semantic Scholar
Cholesterol and Peroxidized Cardiolipin in Mitochondrial Membrane Properties, Permeabilization and Cell Death
J. Montero, M. Marí, A. Colell, A. Morales +3 more
2010Biochimica et Biophysica Acta109 citations Open access
Semantic Scholar
Mechanism of mitochondrial glutathione-dependent hepatocellular susceptibility to TNF despite NF-kappaB activation.
M. Marí, A. Colell, A. Morales, Francisco Caballero +7 more
2008Gastroenterology106 citations Open access
Semantic Scholar
Asymmetric addition of ceramides but not dihydroceramides promotes transbilayer (flip-flop) lipid motion in membranes.
F. Contreras, G. Basañez, A. Alonso, A. Herrmann +1 more
2005Biophysical Journal106 citations Open access
Semantic Scholar
Liposome-bound APO2L/TRAIL is an effective treatment in a rabbit model of rheumatoid arthritis.
L. Martínez-Lostao, F. García-Álvarez, G. Basañez, E. Alegre-Aguarón +5 more
2010Arthritis & Rheumatism102 citations
Semantic Scholar
Mitochondrial cholesterol in health and disease.
C. Garcia-Ruiz, Monserrat Mari, Ana Colell, A. Morales +5 more
2009Histology and Histopathology100 citations
Semantic Scholar
Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals.
E. Jonas, J. Hickman, Mushtaque Chachar, B. Polster +8 more
2004Proceedings of the National Academy of Sciences of the United States of America97 citations Open access
Semantic Scholar
Morphological changes induced by phospholipase C and by sphingomyelinase on large unilamellar vesicles: a cryo-transmission electron microscopy study of liposome fusion.
G. Basañez, M. Begona Ruiz-Arguello, Alicia Alonso, Félix M. Goñi +2 more
1997Biophysical Journal92 citations Open access
Semantic Scholar
Biophysical characterization of recombinant human Bcl-2 and its interactions with an inhibitory ligand, antimycin A.
Kristine M Kim, C. Giedt, G. Basañez, Jason W. O'Neill +6 more
2001Biochemistry90 citations
Semantic Scholar
Liposomes decorated with Apo2L/TRAIL overcome chemoresistance of human hematologic tumor cells.
D. de Miguel, G. Basañez, Diego Sánchez, Patricia Galán Malo +6 more
2013Molecular Pharmaceutics83 citations
Semantic Scholar
Inhibition of Bax-Induced Cytochrome c Release from Neural Cell and Brain Mitochondria by Dibucaine and Propranolol
B. Polster, G. Basañez, M. Young, Motoshi Suzuki +1 more
2003Journal of Neuroscience82 citations Open access
Semantic Scholar
Reconstitution of Proapoptotic BAK Function in Liposomes Reveals a Dual Role for Mitochondrial Lipids in the BAK-driven Membrane Permeabilization Process*
Olatz Landeta, Ane Landajuela, David Gil, S. Taneva +5 more
2011Journal of Biological Chemistry79 citations Open access
Semantic Scholar
The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading
A. Baulies, J. Montero, N. Matías, Naroa Insausti +15 more
2017Redox Biology77 citations Open access
Semantic Scholar
A New View of the Lethal Apoptotic Pore
G. Basañez, L. Soane, J. M. Hardwick
2012PLoS Biology77 citations Open access
Semantic Scholar
Diacylglycerol and the promotion of lamellar-hexagonal and lamellar-isotropic phase transitions in lipids: implications for membrane fusion.
G. Basañez, J. Nieva, E. Rivas, Alicia Alonso +1 more
1996Biophysical Journal74 citations Open access
Semantic Scholar
Topological properties of two cubic phases of a phospholipid : cholesterol: diacylglycerol aqueous system and their possible implications in the phospholipase C‐induced liposome fusion
J. Nieva, Alicia Alonso, G. Basañez, Félix M. Goñi +3 more
1995FEBS Letters71 citations Open access
Semantic Scholar
Endophilin B1/Bif-1 Stimulates BAX Activation Independently from Its Capacity to Produce Large Scale Membrane Morphological Rearrangements*
A. Etxebarria, Oihana Terrones, H. Yamaguchi, Ane Landajuela +4 more
2009Journal of Biological Chemistry60 citations Open access
Semantic Scholar
Origin of the lag period in the phospholipase C cleavage of phospholipids in membranes. Concomitant vesicle aggregation and enzyme activation.
G. Basañez, J. Nieva, Félix M. Goñi, Alicia Alonso
1996Biochemistry58 citations
Semantic Scholar
Specific phospholipid recognition by human immunodeficiency virus type‐1 neutralizing anti‐gp41 2F5 antibody
Silvia Sánchez-Martínez, Maier Lorizate, H. Katinger, R. Kunert +2 more
2006FEBS Letters57 citations
Semantic Scholar
Effect of single chain lipids on phospholipase C-promoted vesicle fusion. A test for the stalk hypothesis of membrane fusion.
G. Basañez, Félix M. Goñi, Alicia Alonso
1998Biochemistry55 citations
Semantic Scholar
Interaction of hagfish cathelicidin antimicrobial peptides with model lipid membranes
G. Basañez, A. Shinnar, J. Zimmerberg
2002FEBS Letters49 citations Open access
Semantic Scholar
Membrane fusion: the process and its energy suppliers
G. Basañez
2002Cellular and Molecular Life Sciences (CMLS)46 citations Open access
Semantic Scholar
BIM and tBID Are Not Mechanistically Equivalent When Assisting BAX to Permeabilize Bilayer Membranes*
Oihana Terrones, A. Etxebarria, Ane Landajuela, Olatz Landeta +2 more
2008Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Dual inhibitory effect of gangliosides on phospholipase C-promoted fusion of lipidic vesicles.
G. Basañez, G. Fidelio, F. Goñi, B. Maggio +1 more
1996Biochemistry38 citations
Semantic Scholar
Interbilayer lipid mixing induced by the human immunodeficiency virus type-1 fusion peptide on large unilamellar vesicles: the nature of the nonlamellar intermediates.
Francisca B. Pereira, José M. Valpuesta, G. Basañez, Félix M. Goñi +1 more
1999Chemistry and Physics of Lipids36 citations
Semantic Scholar
The N-terminal domain of Bcl-xL reversibly binds membranes in a pH-dependent manner.
Guruvasuthevan R. Thuduppathy, Oihana Terrones, J. Craig, G. Basañez +1 more
2006Biochemistry35 citations Open access
Semantic Scholar
Poly(ethylene glycol)‐lipid conjugates inhibit phospholipase C‐induced lipid hydrolysis, liposome aggregation and fusion through independent mechanisms
G. Basañez, Félix M. Goñi, A. Alonso
1997FEBS Letters35 citations
Semantic Scholar
Regulation of antiapoptotic MCL-1 function by gossypol: mechanistic insights from in vitro reconstituted systems.
A. Etxebarria, Olatz Landeta, B. Antonsson, G. Basañez
2008Biochemical Pharmacology31 citations
Semantic Scholar
Unravelling the Bcl-2 Apoptosis Code with a Simple Model System
G. Basañez, J. M. Hardwick
2008PLoS Biology30 citations Open access
Semantic Scholar
Apaf-1 Inhibitors Protect from Unwanted Cell Death in In Vivo Models of Kidney Ischemia and Chemotherapy Induced Ototoxicity
M. Orzáez, M. Sancho, S. Marchán, Laura Mondragón +12 more
2014PLoS ONE29 citations Open access
Semantic Scholar
BFL1 modulates apoptosis at the membrane level through a bifunctional and multimodal mechanism showing key differences with BCLXL
H. Flores‐Romero, Olatz Landeta, Begoña Ugarte-Uribe, Katia Cosentino +3 more
2018Cell Death and Differentiation21 citations Open access
Semantic Scholar
Phospholipase-C-promoted liposome fusion.
Félix M. Goñi, J. Nieva, G. Basañez, Gerardo D. Fidelio +1 more
1994Biochemical Society Transactions21 citations
Semantic Scholar
Membrane insertion of the BAX core, but not latch domain, drives apoptotic pore formation
Hector Flores-Romero, M. García-Porras, G. Basañez
2017Scientific Reports17 citations Open access
Semantic Scholar
Interfacial enzyme activation, non-lamellar phase formation and membrane fusion. Is there a conducting thread?
Félix M. Goñi, G. Basañez, M. Ruiz-Argüello, Alicia Alonso
1998Faraday discussions17 citations
Semantic Scholar
HIV and Apoptosis
G. Basañez, J. Zimmerberg
2001Journal of Experimental Medicine15 citations Open access
Semantic Scholar
Sphingolipids (Galactosylceramide and Sulfatide) in Lamellar−Hexagonal Phospholipid Phase Transitions and in Membrane Fusion†
A. Sáez-Cirión, G. Basañez, G. Fidelio, F. Goñi +2 more
200014 citations
Semantic Scholar
Minimalist Model Systems Reveal Similarities and Differences between Membrane Interaction Modes of MCL1 and BAK*
Olatz Landeta, Ane Landajuela, A. García-Sáez, G. Basañez
2015Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Lipid-dependent bimodal MCL1 membrane activity.
Olatz Landeta, J. G. Valero, Hector Flores-Romero, Itsasne Bustillo-Zabalbeitia +4 more
2014ACS Chemical Biology12 citations
Semantic Scholar

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