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I. English · SciRah

Researcher profile · Semantic Scholar

I. English

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I. English — researcher profile on SciRah

h-index: 9
Works: 44
Citations: 1,992

Most-cited papers

Functional Genomic Landscape of Acute Myeloid Leukemia
J. Tyner, C. Tognon, D. Bottomly, Beth Wilmot +84 more
2018Nature1,210 citations Open access
Semantic Scholar
Integrative Analysis of Drug Response and Clinical Outcome in Acute Myeloid Leukemia
D. Bottomly, Nicola Long, Anna Reister Schultz, S. Kurtz +90 more
2022Cancer Cell351 citations
Semantic Scholar
FGF2 from marrow microenvironment promotes resistance to FLT3 inhibitors in acute myeloid leukemia
E. Traer, Jacqueline Martinez, Nathalie Javidi-Sharifi, A. Agarwal +6 more
2016Cancer Research128 citations Open access
Semantic Scholar
Molecularly targeted drug combinations demonstrate selective effectiveness for myeloid- and lymphoid-derived hematologic malignancies
S. Kurtz, C. Eide, A. Kaempf, V. Khanna +18 more
2017Proceedings of the National Academy of Sciences of the United States of America99 citations Open access
Semantic Scholar
FGF2-FGFR1 signaling regulates release of Leukemia-Protective exosomes from bone marrow stromal cells
Nathalie Javidi-Sharifi, Jacqueline Martinez, I. English, S. Joshi +9 more
2019eLife59 citations Open access
Semantic Scholar
Ponatinib overcomes FGF2-mediated resistance in CML patients without kinase domain mutations.
E. Traer, Nathalie Javidi-Sharifi, A. Agarwal, J. Dunlap +5 more
2014Blood54 citations Open access
Semantic Scholar
Ongoing replication stress tolerance and clonal T cell responses distinguish liver and lung recurrence and outcomes in pancreatic cancer
Jason M. Link, Jenny Eng, C. Pelz, Kevin MacPherson-Hawthorne +34 more
2025Nature Cancer34 citations Open access
Semantic Scholar
Sympathetic Innervation Promotes Arterial Fate by Enhancing Endothelial ERK Activity.
L. Pardanaud, Laurence Pibouin-Fragner, Alexandre Dubrac, T. Mathivet +4 more
2016Circulation Research16 citations Open access
Semantic Scholar
Select Stabilization of a Tumor-Suppressive PP2A Heterotrimer
Vidhi M Shah, I. English, R. Sears
2020TIPS - Trends in Pharmacological Sciences10 citations Open access
Semantic Scholar
Nuclear cGAS mediated Replication Stress and Mitotic Catastrophe can Overcome Gemcitabine Resistance.
S. Park, Kang Jin Jeong, A. Poire, B. Jeong +7 more
2025Cancer Letters6 citations Open access
Semantic Scholar
KRAS-mediated upregulation of CIP2A promotes suppression of PP2A-B56α to initiate pancreatic cancer development
Samantha L. Tinsley, Ella Rose D. Chianis, Rebecca A. Shelley, Gagan K. Mall +14 more
2024Oncogene5 citations Open access
Semantic Scholar
Deconstructing Pancreatic Adenocarcinoma by Targeting the Conductor, MYC
I. English, R. Sears
2020Cancer Discovery5 citations Open access
Semantic Scholar
Correction: FGF2-FGFR1 signaling regulates release of leukemia-protective exosomes from bone marrow stromal cells
Nathalie Javidi-Sharifi, Jacqueline Martinez, I. English, S. Joshi +9 more
2019eLife4 citations Open access
Semantic Scholar
The Prolyl Isomerase PIN1 Impacts Fibroblast Differentiation States and Crosstalk in Pancreatic Cancer
Chloe L Bowman, Colin J. Daniel, Eric J. Carlson, Vidhi M. Shah +33 more
2025Cancer Research3 citations
Semantic Scholar
FGF2 Promotes Resistance To Quizartinib In Vitro, and FGF2 Increases In The Marrow Of Patients Prior To Resistance
E. Traer, Nathalie Javidi-Sharifi, A. Agarwal, J. Dunlap +6 more
20133 citations
Semantic Scholar
Myc and Kras cooperate in adult acinar cells to drive phenotypic heterogeneity, metastasis, and therapeutic resistance in a novel pancreatic cancer mouse model
I. English, P. J. Worth, Kevin MacPherson-Hawthorne, M. Vergara +26 more
2025bioRxiv2 citations
Semantic Scholar
Abstract C102: Investigating rapid metastatic recurrence of pancreatic cancer after resection in a novel, immune-competent, Myc-dependent murine model
J. L. Phipps, I. English, J. Chu, G. Garza +9 more
2024Cancer Research1 citations
Semantic Scholar
Ongoing Replication Stress Response and New Clonal T Cell Development Discriminate Between Liver and Lung Recurrence Sites and Patient Outcomes in Pancreatic Ductal Adenocarcinoma
Jason M. Link, C. Pelz, P. Worth, S. Owen +20 more
2022bioRxiv1 citations Open access
Semantic Scholar
Abstract LT012: The prolyl isomerase PIN1 plays a critical role in fibroblast plasticity to impact pancreatic cancer
Ellen M. Langer, I. English, K. Kresse, Kevin A. MacPherson +4 more
20211 citations
Semantic Scholar
Abstract 1631: FGF2 activation of FGFR1 in head and neck squamous cell carcinoma is associated with more invasive disease and can be attenuated by FGFR inhibition
I. English, Jacqueline Martinez, Edward El Rassi, Mark Schmidt +6 more
20161 citations
Semantic Scholar
Identification of Effective Combinations of Targeted Drugs for Hematologic Malignancies
S. Kurtz, C. Eide, A. Kaempf, V. Khanna +8 more
20161 citations
Semantic Scholar
FGF2 from Bone Marrow Stroma Protects Acute Myeloid Leukemia Cells from the FLT3 Inhibitor Quizartinib and Facilitates Acquisition of Resistance Mutations
E. Traer, Nathalie Javidi-Sharifi, Jacqueline Martinez, I. English +6 more
20161 citations
Semantic Scholar
Abstract 984: FGF2 from the bone marrow promotes resistance to FLT3 inhibitors in AML
Jacqueline Martinez, E. Traer, Nathalie Javidi-Sharifi, A. Agarwal +6 more
20151 citations
Semantic Scholar
FGF2-Containing Exosomes Secreted from Bone Marrow Stromal Cells Protect Leukemia Cells from Tyrosine Kinase Inhibitors
Jacqueline Martinez, Nathalie Javidi-Sharifi, I. English, Shelton A Viola +3 more
20151 citations
Semantic Scholar
A window trial in metastatic pancreatic ductal adenocarcinoma reveals resistance mechanisms to targeting the KRAS-MEK pathway
Motoyuki Tsuda, D. Keith, Colin J. Daniel, C. Pelz +41 more
2025bioRxiv0 citations
Semantic Scholar
Abstract 1438: HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity
Sita Kugel, S. Dobersch, Naomi Yamamoto, Aidan Schutter +15 more
2025Cancer Research0 citations
Semantic Scholar
Abstract B018: RNR inhibitors enhance chemotherapeutic activity in pancreatic cancer cells through altering replication stress
S. Park, K. Jeong, A. Poire, I. English +3 more
2024Cancer Research0 citations
Semantic Scholar
Abstract A061: A novel genetically engineered mouse model of Myc-driven pancreatic cancer recapitulates phenotypic heterogeneity, metastasis, and therapy resistance seen in clinical populations
I. English, P. Worth, Kevin A. MacPherson, Michael B Heskett +21 more
2024Cancer Research0 citations
Semantic Scholar
Abstract 1245: A novel, immune-competent, Myc-dependent model of rapid metastatic recurrence of pancreatic cancer after resection
J. L. Phipps, I. English, J. Chu, Motoyuki Tsuda +7 more
2023Cancer Research0 citations
Semantic Scholar
Surgery accelerates metastatic recurrence of PDAC: A novel, surgical, immune-competent mouse model
J. L. Phipps, I. English, J. Chu, M. Tsuda +5 more
2023HPB0 citations
Semantic Scholar
803 SURGERY ACCELERATES PANCREATIC LIVER METASTASIS IN AN IMMUNE COMPETENT MOUSE MODEL
J. L. Phipps, I. English, J. Chu, Motoyuki Tsuda +7 more
2023Gastroenterology0 citations
Semantic Scholar
Abstract PR012: A novel, immune-competent, Myc-dependent murine model of rapid metastatic recurrence of pancreatic cancer after resection
P. Worth, I. English, Jackie Phipps, Jason M. Link +7 more
2023Cancer Research0 citations
Semantic Scholar
Abstract A067: Myc drives phenotypic heterogeneity, metastasis, and therapy resistance in pancreatic ductal adenocarcinoma
I. English, P. Worth, Amy S Farrell, Brittany L. Allen-Petersen +9 more
2022Cancer Research0 citations
Semantic Scholar
Abstract B026: Surgery accelerates metastatic recurrence in a novel, immune-competent mouse model of resectable pancreatic cancer
J. L. Phipps, I. English, J. Chu, Motoyuki Tsuda +7 more
2022Cancer Research0 citations
Semantic Scholar
Abstract 880: MYC drives phenotypic heterogeneity, metastasis, and therapy resistance in pancreatic ductal adenocarcinoma
I. English, P. Worth, Amy S Farrell, Brittany L. Allen-Petersen +9 more
2022Cancer Research0 citations
Semantic Scholar
Abstract PO-061: Myc drives phenotypic heterogeneity, metastasis, and therapy resistance in pancreatic ductal adenocarcinoma
I. English, P. Worth, Amy T. Farrell, Brittany L. Allen-Petersen +8 more
2021Preclinical Models0 citations
Semantic Scholar
The Prolyl Isomerase PIN1 Plays a Critical Role in Fibroblast Differentiation States to Support Pancreatic Cancer
Ellen M. Langer, Amy S Farrell, Brittany L. Allen-Petersen, Colin J. Daniel +22 more
20210 citations Open access
Semantic Scholar
Abstract PO-113: The prolyl isomerase PIN1 plays a critical role in fibroblast differentiation states to support pancreatic cancer
Ellen M. Langer, I. English, V. Shah, Kevin A. MacPherson +6 more
2021Tumor Microenvironment0 citations
Semantic Scholar
Abstract IA-06: Heterotypic 3D bioprinted tissues to study pancreatic cancer
Ellen M. Langer, Brittany L. Allen-Petersen, I. English, Jason M. Link +1 more
2020Oral Presentations - Invited Abstracts0 citations
Semantic Scholar
Abstract A27: Heterotypic 3D bioprinted tissues to interrogate tumor-microenvironment crosstalk in cancer
Ellen M. Langer, I. English, Megan A Turnidge, Zinab O. Doha +1 more
20200 citations
Semantic Scholar
Author response: FGF2-FGFR1 signaling regulates release of Leukemia-Protective exosomes from bone marrow stromal cells
Nathalie Javidi-Sharifi, Jacqueline Martinez, I. English, S. Joshi +9 more
20190 citations Open access
Semantic Scholar
TITLE: FGF2 from marrow microenvironment promotes resistance to FLT3 inhibitors in acute myeloid leukemia Short title: FGF2 PROMOTES RESISTANCE IN FLT3 AML
E. Traer, Jacqueline Martinez, Nathalie Javidi-Sharifi, A. Agarwal +6 more
20160 citations
Semantic Scholar
FGF2 Mediates Resistance In CML Patients In The Absence Of Kinase Domain Mutations, and Resistance Is Overcome By Ponatinib
Nathalie Javidi-Sharifi, A. Agarwal, J. Dunlap, I. English +4 more
20130 citations
Semantic Scholar
Molecularly Targeted Drug Combinations Molecularly Targeted Drug Combinations Demonstrate Selective Effectiveness for Myeloid-Demonstrate Selective Effectiveness for Myeloid-and Lymphoidderived Hematologic Malignancies and Lymphoidderived Hematologic Malignancies
S. Kurtz, Christopher A. Eide, A. Kaempf, V. Khanna +18 more
0 citations
Semantic Scholar

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E. Traer×16
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E. Traer — researcher profile on SciRah
B. Druker×15
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C. Pelz×15
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R. Sears×15
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J. Tyner — researcher profile on SciRah

Jacqueline Martinez×14

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Colin J. Daniel×13

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Ellen M. Langer×13

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Nathalie Javidi-Sharifi×11

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Nathalie Javidi-Sharifi — researcher profile on SciRah

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