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R. Tytarenko · SciRah

Researcher profile · Semantic Scholar

R. Tytarenko

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R. Tytarenko — researcher profile on SciRah

h-index: 22
Works: 75
Citations: 1,848

Most-cited papers

Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing
L. Rasche, S. Chavan, O. Stephens, P. Patel +19 more
2017Nature Communications388 citations Open access
Semantic Scholar
Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma.
N. Weinhold, C. Ashby, L. Rasche, S. Chavan +21 more
2016Blood206 citations Open access
Semantic Scholar
Combination of Flow Cytometry and Functional Imaging for Monitoring of Residual Disease in Myeloma
L. Rasche, Daisy V. Alapat, M. Kumar, G. Gershner +18 more
2018Leukemia146 citations Open access
Semantic Scholar
The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
E. Boyle, S. Deshpande, R. Tytarenko, C. Ashby +19 more
2021Nature Communications107 citations Open access
Semantic Scholar
The presence of large focal lesions is a strong independent prognostic factor in multiple myeloma.
L. Rasche, E. Angtuaco, Terri L Alpe, G. Gershner +18 more
2018Blood107 citations Open access
Semantic Scholar
Complement Mediated Apoptosis Leads to the Loss of Retinal Ganglion Cells in Animal Model of Glaucoma
P. Jha, Himanshu K. Banda, R. Tytarenko, P. Bora +1 more
2011Molecular Immunology79 citations Open access
Semantic Scholar
Polyethylene Glycol (PEG)-induced Mouse Model of Choroidal Neovascularization*
V. Lyzogubov, R. Tytarenko, Juan Liu, N. Bora +1 more
2011Journal of Biological Chemistry62 citations Open access
Semantic Scholar
Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma
A. Mikulasova, C. Ashby, R. Tytarenko, Ping-Ping Qu +18 more
2019Haematologica58 citations Open access
Semantic Scholar
Recombinant Membrane-targeted Form of CD59 Inhibits the Growth of Choroidal Neovascular Complex in Mice*
N. Bora, P. Jha, V. Lyzogubov, S. Kaliappan +5 more
2010Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Relationship between Complement Membrane Attack Complex, Chemokine (C-C Motif) Ligand 2 (CCL2) and Vascular Endothelial Growth Factor in Mouse Model of Laser-induced Choroidal Neovascularization*
Juan Liu, P. Jha, V. Lyzogubov, R. Tytarenko +2 more
2011Journal of Biological Chemistry54 citations Open access
Semantic Scholar
Role of ocular complement factor H in a murine model of choroidal neovascularization.
V. Lyzogubov, R. Tytarenko, P. Jha, Juan Liu +2 more
2010American Journal of Pathology54 citations Open access
Semantic Scholar
Immunohistochemical analysis of S6K1 and S6K2 localization in human breast tumors.
V. Filonenko, R. Tytarenko, Sergey K Azatjan, L. Savinska +4 more
2004Experimental oncology53 citations
Semantic Scholar
Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition?
C. Pawlyn, A. Loehr, C. Ashby, R. Tytarenko +7 more
2018Leukemia47 citations Open access
Semantic Scholar
Complement regulatory protein CD46 protects against choroidal neovascularization in mice.
V. Lyzogubov, Xiaobo Wu, P. Jha, R. Tytarenko +6 more
2014American Journal of Pathology43 citations Open access
Semantic Scholar
Artesunate overcomes drug resistance in multiple myeloma by inducing mitochondrial stress and non-caspase apoptosis
X. Papanikolaou, Sarah K. Johnson, T. Garg, E. Tian +6 more
2014OncoTarget41 citations Open access
Semantic Scholar
BRAF and DIS3 Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma
E. Boyle, C. Ashby, R. Tytarenko, S. Deshpande +24 more
2020Clinical Cancer Research37 citations Open access
Semantic Scholar
The Use of Topical Honey in the Treatment of Corneal Abrasions and Endotoxin-Induced Keratitis in an Animal Model
S. Uwaydat, P. Jha, R. Tytarenko, H. Brown +3 more
2011Current Eye Research37 citations
Semantic Scholar
Monitoring treatment response and disease progression in myeloma with circulating cell‐free DNA
S. Deshpande, R. Tytarenko, Yan Wang, E. Boyle +9 more
2020European Journal of Haematology32 citations
Semantic Scholar
The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma
Samrat Roy Choudhury, C. Ashby, R. Tytarenko, M. Bauer +10 more
2020Journal of Hematology & Oncology30 citations Open access
Semantic Scholar
Kinase domain activation through gene rearrangement in multiple myeloma
G. Morgan, Jie He, R. Tytarenko, P. Patel +18 more
2018Leukemia27 citations Open access
Semantic Scholar
Polyethylene glycol induced mouse model of retinal degeneration.
V. Lyzogubov, N. Bora, R. Tytarenko, P. Bora
2014Experimental Eye Research25 citations
Semantic Scholar
Alcohol and nicotine consumption exacerbates choroidal neovascularization by modulating the regulation of complement system
S. Kaliappan, P. Jha, V. Lyzogubov, R. Tytarenko +2 more
2008FEBS Letters22 citations Open access
Semantic Scholar
Inhibitory role of adiponectin peptide I on rat choroidal neovascularization
V. Lyzogubov, R. Tytarenko, N. Bora, P. Bora
2012Biochimica et Biophysica Acta20 citations Open access
Semantic Scholar
The effect of nicotine on anti-VEGF therapy in a mouse model of neovascular age-related macular degeneration
S. Davis, V. Lyzogubov, R. Tytarenko, A. Safar +2 more
2012Retina17 citations Open access
Semantic Scholar
Poor overall survival in hyperhaploid multiple myeloma is defined by double-hit bi-allelic inactivation of TP53
C. Ashby, R. Tytarenko, Yan Wang, N. Weinhold +11 more
2019OncoTarget15 citations Open access
Semantic Scholar
Crucial role of apoptosis in the resolution of experimental autoimmune anterior uveitis.
P. Jha, B. Matta, V. Lyzogubov, R. Tytarenko +2 more
2007Investigative Ophthalmology and Visual Science14 citations
Semantic Scholar
Two Cases of Vancomycin-Resistant Enterococcus faecium Bacteremia With Development of Daptomycin-Resistant Phenotype and its Detection Using Oxford Nanopore Sequencing
Zulema Udaondo, Piroon Jenjaroenpun, T. Wongsurawat, Erik Meyers +8 more
2020Open Forum Infectious Diseases13 citations Open access
Semantic Scholar
High Risk Multiple Myeloma Demonstrates Marked Spatial Genomic Heterogeneity Between Focal Lesions and Random Bone Marrow; Implications for Targeted Therapy and Treatment Resistance
N. Weinhold, S. Chavan, C. Heuck, O. Stephens +17 more
20158 citations
Semantic Scholar
Complete Genome Sequences of Four Isolates of Vancomycin-Resistant Enterococcus faecium with the vanA Gene and Two Daptomycin Resistance Mutations, Obtained from Two Inpatients with Prolonged Bacteremia
Piroon Jenjaroenpun, T. Wongsurawat, Zulema Udaondo, C. Anderson +8 more
2020Microbiology Resource Announcements5 citations Open access
Semantic Scholar
Draft Genome Sequences of 48 Vancomycin-Resistant Enterococcus faecium Strains Isolated from Inpatients with Bacteremia and Urinary Tract Infection
Zulema Udaondo, T. Wongsurawat, Piroon Jenjaroenpun, C. Anderson +8 more
2019Microbiology Resource Announcements5 citations Open access
Semantic Scholar
Characterization of the Mutational Landscape of Multiple Myeloma Using Comprehensive Genomic Profiling
C. Heuck, Donald J. Johann, B. Walker, Caleb K Stein +13 more
20145 citations
Semantic Scholar
Chromothripsis and Chromoplexy Are Associated with DNA Instability and Adverse Clinical Outcome in Multiple Myeloma
C. Ashby, M. Bauer, Yan Wang, C. Wardell +17 more
2018Blood4 citations
Semantic Scholar
Analysis of the Sub-Clonal Structure of Smoldering Myeloma over Time Provides a New Means of Disease Monitoring and Highlights Evolutionary Trajectories Leading to Myeloma
E. Boyle, F. Davies, S. Deshpande, R. Tytarenko +15 more
2019Blood3 citations Open access
Semantic Scholar
Poor Overall Survival in Hyperhaploid Multiple Myeloma Is Defined By Double-Hit Bi-Allelic Inactivation of TP53
C. Ashby, Yan Wang, R. Tytarenko, C. Schinke +7 more
2018Blood3 citations Open access
Semantic Scholar
Translocations and Jumping Rearrangements at 8q24 Result in over-Expression of MYC and are Key Drivers of Disease Progression
E. Tian, J. Sawyer, O. Stephens, R. Tytarenko +7 more
20163 citations Open access
Semantic Scholar
The Mutational Landscape of Primary Plasma Cell Leukemia
C. Schinke, C. Ashby, Yan Wang, R. Tytarenko +14 more
2018Blood2 citations Open access
Semantic Scholar
Abstract 5324: Intragenic DNA-hypomethylation promotes overexpression ofITGB7in MF subgroup of multiple myeloma
Samrat Roy Choudhury, C. Ashby, R. Tytarenko, Yan Wang +7 more
2018Molecular and Cellular Biology / Genetics2 citations
Semantic Scholar
Extracting Prognostic Molecular Information from PET-CT Imaging of Multiple Myeloma Using Radiomic Approaches
C. Wardell, Terri L Alpe, Phil Farmer, M. Rutherford +14 more
2018Blood2 citations
Semantic Scholar
Loss of heterozygosity in multiple myeloma: A role for PARP inhibition?
C. Pawlyn, A. Loehr, R. Tytarenko, S. Deshpande +7 more
20172 citations
Semantic Scholar
A Survey of Fusion Genes in Myeloma Identifies Kinase Domain Activation Which Could be Targeted with Available Treatments
B. Walker, S. Chavan, Jie He, R. Tytarenko +22 more
20162 citations Open access
Semantic Scholar
Extensive Regional Intra-Clonal Heterogeneity in Multiple Myeloma - Implications for Diagnostics, Risk Stratification and Targeted Treatment
N. Weinhold, S. Chavan, L. Rasche, O. Stephens +21 more
20162 citations
Semantic Scholar
Impact of Minimal Residual Disease in High and Standard Risk Multiple Myeloma
C. Schinke, S. Deshpande, A. Mitchell, M. Faham +21 more
20152 citations
Semantic Scholar
The Antimalarial Agent Artesunate Exerts Its Antimyeloma Activity By Affecting The Mitochondria and The Reactive Oxygen Status Of The Myeloma Cells and Its Efficacy Depends On Intracellular Bivalent Iron Levels
Sarah K. Johnson, T. Garg, E. Tian, R. Tytarenko +3 more
20132 citations
Semantic Scholar
Relationship Between Complement Activation and Choroidal Neovascularization in Type II Diabetes
V. Lyzogubov, R. Tytarenko, P. Bora, N. Bora
20102 citations
Semantic Scholar
Long-Term Follow-up Identifies Double Hit and Key Mutations As Impacting Progression Free and Overall Survival in Multiple Myeloma
C. Ashby, E. Boyle, R. Tytarenko, Hongwei Wang +15 more
2018Blood1 citations Open access
Semantic Scholar
Genome Wide Mapping of Methylated and Hydroxyl-Methylated Cytosines Using a Modified HpaII Tiny Fragment Enrichment by Ligation Mediated PCR Tagged Sequencing Protocol.
Sanchari Battachariyya, R. Tytarenko, C. Heuck, J. Greally +1 more
2018Methods in molecular biology1 citations
Semantic Scholar
Next Generation Sequencing (NGS) Based Minimal Residual Disease (MRD) Testing Is Highly Predictive of Overall and Progression Free Survival in the Total Therapy Trials and Shows Different Prognostic Implications in High Vs Standard Risk Multiple Myeloma
C. Schinke, S. Deshpande, Hongwei Wang, V. Carlton +24 more
20161 citations
Semantic Scholar
The Impact of Combination Chemotherapy and Tandem Stem Cell Transplant on Clonal Substructure and Mutational Pattern at Relapse of MM
C. Heuck, N. Weinhold, E. Peterson, M. Bauer +18 more
20151 citations
Semantic Scholar
Role Of CD46 In Laser Induced Choroidal Neovascularization
V. Lyzogubov, R. Tytarenko, P. Jha, Xiaobo Wu +4 more
20111 citations
Semantic Scholar
The Effect of Nicotine on Anti-VEGF Therapy in a Mouse Model of Neovascular Age-Related Macular Degeneration
S. Davis, V. Lyzogubov, R. Tytarenko, A. Safar +2 more
20101 citations
Semantic Scholar

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