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I. Frick · SciRah

Researcher profile · Semantic Scholar

I. Frick

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I. Frick — researcher profile on SciRah

h-index: 30
Works: 84
Citations: 4,756

Most-cited papers

Helicobacter pylori adhesin binding fucosylated histo-blood group antigens revealed by retagging.
D. Ilver, A. Arnqvist, Johan Ögren, I. Frick +6 more
1998Science1,273 citations
Semantic Scholar
Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL‐37
A. Schmidtchen, I. Frick, E. Andersson, H. Tapper +1 more
2002Molecular Microbiology454 citations Open access
Semantic Scholar
Gram-positive anaerobic cocci--commensals and opportunistic pathogens.
E. C. Murphy, I. Frick
2013FEMS Microbiology Reviews329 citations Open access
Semantic Scholar
SIC, a Secreted Protein of Streptococcus pyogenesThat Inactivates Antibacterial Peptides*
I. Frick, P. Åkesson, M. Rasmussen, A. Schmidtchen +1 more
2003Journal of Biological Chemistry200 citations Open access
Semantic Scholar
Dermatan sulphate is released by proteinases of common pathogenic bacteria and inactivates antibacterial α‐defensin
A. Schmidtchen, I. Frick, L. Björck
2001Molecular Microbiology181 citations Open access
Semantic Scholar
The contact system—a novel branch of innate immunity generating antibacterial peptides
I. Frick, P. Åkesson, H. Herwald, M. Mörgelin +3 more
2006EMBO Journal166 citations Open access
Semantic Scholar
Size-selectivity of the glomerular barrier to high molecular weight proteins: upper size limitations of shunt pathways.
J. Tencer, I. Frick, Björn W. Öquist, P. Alm +1 more
1998Kidney International150 citations Open access
Semantic Scholar
The dual role of the contact system in bacterial infectious disease
I. Frick, L. Björck, H. Herwald
2007Thrombosis and Haemostasis137 citations
Semantic Scholar
Crystal Structure and Biological Implications of a Bacterial Albumin Binding Module in Complex with Human Serum Albumin*
S. Lejon, I. Frick, L. Björck, M. Wikström +1 more
2004Journal of Biological Chemistry119 citations Open access
Semantic Scholar
Structure, Specificity, and Mode of Interaction for Bacterial Albumin-binding Modules*
M. Johansson, I. Frick, H. Nilsson, P. Kraulis +9 more
2002Journal of Biological Chemistry115 citations Open access
Semantic Scholar
Virulent aggregates of Streptococcus pyogenes are generated by homophilic protein–protein interactions
I. Frick, M. Mörgelin, L. Björck
2000Molecular Microbiology114 citations
Semantic Scholar
Interactions between M proteins of Streptococcus pyogenes and glycosaminoglycans promote bacterial adhesion to host cells.
I. Frick, A. Schmidtchen, U. Sjöbring
2003European Journal of Biochemistry107 citations Open access
Semantic Scholar
The CXC chemokine MIG/CXCL9 is important in innate immunity against Streptococcus pyogenes.
A. Egesten, Mette Eliasson, H. Johansson, A. Olin +5 more
2007Journal of Infectious Diseases104 citations
Semantic Scholar
Convergent evolution among immunoglobulin G-binding bacterial proteins.
I. Frick, M. Wikström, Sture Forsén, Torbjörn Drakenberg +3 more
1992Proceedings of the National Academy of Sciences of the United States of America98 citations Open access
Semantic Scholar
Finegoldia magna, an Anaerobic Gram-Positive Bacterium of the Normal Human Microbiota, Induces Inflammation by Activating Neutrophils
Ariane Neumann, L. Björck, I. Frick
2020Frontiers in Microbiology84 citations Open access
Semantic Scholar
Structure and stability of protein H and the M1 protein from Streptococcus pyogenes. Implications for other surface proteins of gram-positive bacteria.
Bo H. K. Nilson, I. Frick, Per Åkesson, Sture Forsén +3 more
1995Biochemistry83 citations
Semantic Scholar
Protein H — a surface protein of Streptococcus pyogenes with separate binding sites for lgG and albumin
I. Frick, Per Åkesson, J. Cooney, U. Sjöbring +6 more
1994Molecular Microbiology81 citations
Semantic Scholar
Constitutive and Inflammation-Dependent Antimicrobial Peptides Produced by Epithelium Are Differentially Processed and Inactivated by the Commensal Finegoldia magna and the Pathogen Streptococcus pyogenes
I. Frick, Sara L. Nordin, Maria Baumgarten, M. Mörgelin +3 more
2011Journal of Immunology71 citations Open access
Semantic Scholar
Protein H‐‐a bacterial surface protein with affinity for both immunoglobulin and fibronectin type III domains.
I. Frick, K. Crossin, G. Edelman, L. Björck
1995EMBO Journal64 citations Open access
Semantic Scholar
Identification of a Streptococcal Octapeptide Motif Involved in Acute Rheumatic Fever*
K. Dinkla, D. P. Nitsche-Schmitz, V. Barroso, Silvana Reissmann +4 more
2007Journal of Biological Chemistry63 citations Open access
Semantic Scholar
SufA--a novel subtilisin-like serine proteinase of Finegoldia magna.
C. Karlsson, M. Andersson, M. Collin, A. Schmidtchen +2 more
2007Microbiology57 citations Open access
Semantic Scholar
Binding of Albumin Promotes Bacterial Survival at the Epithelial Surface*
A. Egesten, I. Frick, M. Mörgelin, A. Olin +1 more
2010Journal of Biological Chemistry54 citations Open access
Semantic Scholar
Identification of a novel protein promoting the colonization and survival of Finegoldia magna, a bacterial commensal and opportunistic pathogen
I. Frick, C. Karlsson, M. Mörgelin, A. Olin +5 more
2008Molecular Microbiology46 citations Open access
Semantic Scholar
Identification of molecular mechanisms used by Finegoldia magna to penetrate and colonize human skin
E. C. Murphy, M. Mörgelin, Dieter P. Reinhardt, A. Olin +2 more
2014Molecular Microbiology44 citations Open access
Semantic Scholar
Binding of Complement Inhibitor C4b-binding Protein to a Highly Virulent Streptococcus pyogenes M1 Strain Is Mediated by Protein H and Enhances Adhesion to and Invasion of Endothelial Cells*
David Ermert, Antonin Weckel, Vaibhav Agarwal, I. Frick +2 more
2013Journal of Biological Chemistry43 citations Open access
Semantic Scholar
Activation of the Contact System at the Surface of Fusobacterium necrophorum Represents a Possible Virulence Mechanism in Lemièrre's Syndrome
Karin Holm, I. Frick, L. Björck, M. Rasmussen
2011Infection and Immunity38 citations Open access
Semantic Scholar
Streptococcal Protein FOG, a Novel Matrix Adhesin Interacting with Collagen I in Vivo*
D. Nitsche, H. Johansson, I. Frick, M. Mörgelin
2006Journal of Biological Chemistry38 citations Open access
Semantic Scholar
Interaction of Bacteroides fragilis and Bacteroides thetaiotaomicron with the kallikrein–kinin system
E. C. Murphy, M. Mörgelin, J. Cooney, I. Frick
2011Microbiology37 citations Open access
Semantic Scholar
SufA of the Opportunistic Pathogen Finegoldia magna Modulates Actions of the Antibacterial Chemokine MIG/CXCL9, Promoting Bacterial Survival during Epithelial Inflammation
C. Karlsson, Mette Eliasson, A. Olin, M. Mörgelin +4 more
2009Journal of Biological Chemistry37 citations Open access
Semantic Scholar
Group G Streptococcal IgG Binding Molecules FOG and Protein G Have Different Impacts on Opsonization by C1q*
D. P. Nitsche-Schmitz, H. Johansson, Inka Sastalla, Silvana Reissmann +2 more
2007Journal of Biological Chemistry37 citations Open access
Semantic Scholar
Protein SIC Secreted from Streptococcus pyogenes Forms Complexes with Extracellular Histones That Boost Cytokine Production
J. Westman, B. Chakrakodi, J. Snäll, M. Mörgelin +7 more
2018Frontiers in Immunology29 citations Open access
Semantic Scholar
M1 protein of Streptococcus pyogenes increases production of the antibacterial CXC chemokine MIG/CXCL9 in pharyngeal epithelial cells.
Mette Eliasson, I. Frick, M. Collin, O. Sørensen +2 more
2007Microbial Pathogenesis25 citations
Semantic Scholar
Antibacterial Activity of the Contact and Complement Systems Is Blocked by SIC, a Protein Secreted by Streptococcus pyogenes
I. Frick, Oonagh Shannon, P. Åkesson, M. Mörgelin +3 more
2010Journal of Biological Chemistry24 citations Open access
Semantic Scholar
SufA – a bacterial enzyme that cleaves fibrinogen and blocks fibrin network formation
C. Karlsson, M. Mörgelin, M. Collin, R. Lood +4 more
2009Microbiology24 citations Open access
Semantic Scholar
Protein FOG--a streptococcal inhibitor of neutrophil function.
H. Johansson, M. Mörgelin, I. Frick
2004Microbiology22 citations Open access
Semantic Scholar
FAF and SufA: Proteins of Finegoldia magna That Modulate the Antibacterial Activity of Histones
E. C. Murphy, T. Mohanty, I. Frick
2013Journal of Innate Immunity17 citations Open access
Semantic Scholar
Identification of pili on the surface of Finegoldia magna--a gram-positive anaerobic cocci.
E. C. Murphy, Robert Janulczyk, C. Karlsson, M. Mörgelin +1 more
2014Anaerobe16 citations Open access
Semantic Scholar
Streptococcal inhibitor of complement (SIC) modulates fibrinolysis and enhances bacterial survival within fibrin clots
I. Frick, Oonagh Shannon, Ariane Neumann, C. Karlsson +2 more
2018Journal of Biological Chemistry15 citations Open access
Semantic Scholar
Saliva-Induced Clotting Captures Streptococci: Novel Roles for Coagulation and Fibrinolysis in Host Defense and Immune Evasion
Kristofer Wollein Waldetoft, T. Mohanty, C. Karlsson, M. Mörgelin +3 more
2016Infection and Immunity15 citations Open access
Semantic Scholar
Streptococcal Surface Proteins Activate the Contact System and Control Its Antibacterial Activity
Kristofer Wollein Waldetoft, L. Svensson, M. Mörgelin, A. Olin +3 more
2012Journal of Biological Chemistry15 citations Open access
Semantic Scholar
IdeS, a secreted proteinase of Streptococcus pyogenes, is bound to a nuclease at the bacterial surface where it inactivates opsonizing IgG antibodies
I. Frick, L. Happonen, Sebastian Wrighton, P. Nordenfelt +1 more
2023Journal of Biological Chemistry14 citations Open access
Semantic Scholar
Expression of MIG/CXCL9 in Cystic Fibrosis and Modulation of Its Activities by Elastase of Pseudomonas aeruginosa
S. Jovic, Medya M. Shikhagaie, M. Mörgelin, S. Kjellström +4 more
2014Journal of Innate Immunity14 citations Open access
Semantic Scholar
Streptococcal protein SIC activates monocytes and induces inflammation
Ariane Neumann, L. Happonen, C. Karlsson, Wael Bahnan +2 more
2021iScience13 citations Open access
Semantic Scholar
Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease
L. Tan, Mark Reglinski, D. Teo, Nada Reza +7 more
2020npj Vaccines13 citations Open access
Semantic Scholar
Antigen-induced release of histamine from rat tissues in vitro: dissociation in development of serosal mast cell, lung tissue, and tracheal tissue response capacity.
H. Bergstrand, I. Frick, B. Lindhqvist, B. Lundqvist +2 more
1982International Archives of Allergy and Applied Immunology11 citations
Semantic Scholar
Substrate profiling of Finegoldia magna SufA protease, inhibitor screening and application to prevent human fibrinogen degradation and bacteria growth in vitro.
E. Burchacka, M. Sieńczyk, I. Frick, M. Wysocka +2 more
2014Biochimie10 citations
Semantic Scholar
Anti‐IgE‐Induced Histamine Release from Human Basophilic Leukocytes: Inhibition Depends on Nature and Concentration of Inhibitor and Secretagogue
H. Bergstrand, A. Björnsson, I. Frick, B. Lundquist +1 more
1982Allergy. European Journal of Allergy and Clinical Immunology9 citations
Semantic Scholar
Group G streptococci mediate fibrinogen-dependent platelet aggregation leading to transient entrapment in platelet aggregates.
L. Svensson, I. Frick, Oonagh Shannon
2016Microbiology5 citations Open access
Semantic Scholar
Functional and Structural Properties of a Novel Protein and Virulence Factor (Protein sHIP) in Streptococcus pyogenes *
M. Wiśniewska, L. Happonen, F. Kahn, M. Varjosalo +10 more
2014Journal of Biological Chemistry5 citations Open access
Semantic Scholar
Surface proteins of group G Streptococcus in different phases of growth: patterns of production and implications for the host-bacteria relationship.
Kristofer Wollein Waldetoft, C. Karlsson, M. Gram, J. Malmström +3 more
2014Microbiology5 citations Open access
Semantic Scholar

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