Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

M. Arai · SciRah

Researcher profile · Semantic Scholar

M. Arai

Share profile

M. Arai — researcher profile on SciRah

h-index: 28
Works: 176
Citations: 2,759

Most-cited papers

Catalytic asymmetric synthesis of mixed 3,3'-bisindoles and their evaluation as Wnt signaling inhibitors.
T. Arai, Y. Yamamoto, Atsuko Awata, Kentaro Kamiya +2 more
2013Angewandte Chemie75 citations
Semantic Scholar
Calotropin: A Cardenolide from Calotropis gigantea that Inhibits Wnt Signaling by Increasing Casein Kinase 1α in Colon Cancer Cells
H. Park, K. Toume, M. Arai, S. Sadhu +2 more
2014ChemBioChem46 citations
Semantic Scholar
Natural compounds with Wnt signal modulating activity.
Rolly G. Fuentes, M. Arai, M. Ishibashi
2015Natural product reports (Print)36 citations
Semantic Scholar
9-Hydroxycanthin-6-one, a β-Carboline Alkaloid from Eurycoma longifolia, Is the First Wnt Signal Inhibitor through Activation of Glycogen Synthase Kinase 3β without Depending on Casein Kinase 1α.
Kensuke Ohishi, K. Toume, M. Arai, T. Koyano +4 more
2015Journal of Natural Products36 citations Open access
Semantic Scholar
Xylogranin B: a potent Wnt signal inhibitory limonoid from Xylocarpus granatum.
K. Toume, Kentaro Kamiya, M. Arai, Naomi Mori +3 more
2013Organic Letters34 citations
Semantic Scholar
Ricinine: a pyridone alkaloid from Ricinus communis that activates the Wnt signaling pathway through casein kinase 1α.
Kensuke Ohishi, K. Toume, M. Arai, S. Sadhu +4 more
2014Bioorganic & Medicinal Chemistry32 citations
Semantic Scholar
Boesenberols, Pimarane Diterpenes with TRAIL-Resistance-Overcoming Activity from Boesenbergia pandurata.
U. Karmakar, Naoki Ishikawa, M. Arai, F. Ahmed +3 more
2016Journal of Natural Products30 citations
Semantic Scholar
Sesquiterpenes with TRAIL-resistance overcoming activity from Xanthium strumarium.
U. Karmakar, Naoki Ishikawa, K. Toume, M. Arai +3 more
2015Bioorganic & Medicinal Chemistry30 citations
Semantic Scholar
Physalin H from Solanum nigrum as an Hh signaling inhibitor blocks GLI1–DNA-complex formation
M. Arai, Kyoko Uchida, S. Sadhu, F. Ahmed +1 more
2014Beilstein Journal of Organic Chemistry28 citations Open access
Semantic Scholar
Hedgehog inhibitors from Withania somnifera.
Tatsuro Yoneyama, M. Arai, S. Sadhu, F. Ahmed +1 more
2015Bioorganic & Medicinal Chemistry Letters26 citations
Semantic Scholar
Chromomycins A2 and A3 from Marine Actinomycetes with TRAIL Resistance-Overcoming and Wnt Signal Inhibitory Activities
K. Toume, Kentaro Tsukahara, Hanako Ito, M. Arai +1 more
2014Marine Drugs25 citations Open access
Semantic Scholar
Hh signaling inhibitors from Vitex negundo; naturally occurring inhibitors of the GLI1-DNA complex.
M. Arai, T. Fujimatsu, Kyoko Uchida, S. Sadhu +2 more
2013Molecular Biosystems25 citations
Semantic Scholar
The Notch inhibitor cowanin accelerates nicastrin degradation
M. Arai, Ryuta Akamine, Anna Tsuchiya, Tatsuro Yoneyama +3 more
2018Scientific Reports23 citations Open access
Semantic Scholar
Scopadulciol, Isolated from Scoparia dulcis, Induces β-Catenin Degradation and Overcomes Tumor Necrosis Factor-Related Apoptosis Ligand Resistance in AGS Human Gastric Adenocarcinoma Cells.
Rolly G. Fuentes, K. Toume, M. Arai, S. Sadhu +2 more
2015Journal of Natural Products23 citations
Semantic Scholar
Bioactive Secondary Metabolites with Unique Aromatic and Heterocyclic Structures Obtained from Terrestrial Actinomycetes Species.
M. Abdelfattah, M. Arai, M. Ishibashi
2016Chemical and pharmaceutical bulletin22 citations Open access
Semantic Scholar
Prenylated flavonoids and resveratrol derivatives isolated from Artocarpus communis with the ability to overcome TRAIL resistance.
K. Toume, T. Habu, M. Arai, T. Koyano +2 more
2015Journal of Natural Products22 citations
Semantic Scholar
Naturally occurring Ngn2 promoter activators from Butea superba.
M. Arai, Kazune Koryudzu, T. Koyano, T. Kowithayakorn +1 more
2013Molecular Biosystems22 citations
Semantic Scholar
Notch Inhibitors from Calotropis gigantea That Induce Neuronal Differentiation of Neural Stem Cells.
Tatsuro Yoneyama, M. Arai, Ryuta Akamine, Kazune Koryudzu +6 more
2017Journal of Natural Products21 citations Open access
Semantic Scholar
Cerasoidine, a Bis-aporphine Alkaloid Isolated from Polyalthia cerasoides during Screening for Wnt Signal Inhibitors.
T. Shono, Naoki Ishikawa, K. Toume, M. Arai +4 more
2016Journal of Natural Products21 citations
Semantic Scholar
Coculture of a Pathogenic Actinomycete and Animal Cells To Produce Nocarjamide, a Cyclic Nonapeptide with Wnt Signal-Activating Effect.
Yasumasa Hara, M. Arai, K. Toume, H. Masu +4 more
2018Organic Letters20 citations Open access
Semantic Scholar
Hedgehog/GLI-mediated transcriptional activity inhibitors from Crinum asiaticum
M. Arai, Ryuta Akamine, S. Sadhu, F. Ahmed +1 more
2015Journal of Natural Medicines20 citations
Semantic Scholar
Hes1 inhibitor isolated by target protein oriented natural products isolation (TPO-NAPI) of differentiation activators of neural stem cells
M. Arai, Naoki Ishikawa, Mitsuha Tanaka, K. Uemura +6 more
2015Chemical Science20 citations Open access
Semantic Scholar
Inubosins A, B, and C are acridine alkaloids isolated from a culture of Streptomyces sp. IFM 11440 with Ngn2 promoter activity.
M. Arai, Kazune Koryudzu, M. Ishibashi
2015Journal of Natural Products18 citations
Semantic Scholar
The Notch Inhibitors Isolated from Nerium indicum.
M. Arai, Ryuta Akamine, N. Hayashi, T. Koyano +2 more
2018Journal of Natural Products17 citations Open access
Semantic Scholar
Coronaridine, an iboga type alkaloid from Tabernaemontana divaricata, inhibits the Wnt signaling pathway by decreasing β-catenin mRNA expression.
Kensuke Ohishi, K. Toume, M. Arai, S. Sadhu +2 more
2015Bioorganic & Medicinal Chemistry Letters17 citations
Semantic Scholar
Phenolic compounds from the bark of Oroxylum indicum activate the Ngn2 promoter
Rolly G. Fuentes, M. Arai, S. Sadhu, F. Ahmed +1 more
2015Journal of Natural Medicines17 citations
Semantic Scholar
Evaluation of Naturally Occurring HIF‐1 Inhibitors for Pulmonary Arterial Hypertension
M. Arai, Kota Sakuraba, Yoshinori Makita, Yasumasa Hara +1 more
2021ChemBioChem16 citations
Semantic Scholar
Stereochemical Assignment and Biological Evaluation of BE-14106 Unveils the Importance of One Acetate Unit for the Antifungal Activity of Polyene Macrolactams.
Kohei Fujita, Ryosuke Sugiyama, Shin-ichi Nishimura, Naoki Ishikawa +3 more
2016Journal of Natural Products16 citations Open access
Semantic Scholar
GLI1 Inhibitors Identified by Target Protein Oriented Natural Products Isolation (TPO-NAPI) with Hedgehog Inhibition.
M. Arai, Fumie Ochi, Yoshinori Makita, T. Chiba +8 more
2018ACS Chemical Biology15 citations Open access
Semantic Scholar
Boesenberols I–K, new isopimarane diterpenes from Boesenbergia pandurata with TRAIL-resistance overcoming activity
U. Karmakar, M. Arai, T. Koyano, T. Kowithayakorn +1 more
201715 citations
Semantic Scholar
Dehydropropylpantothenamide isolated by a co-culture of Nocardia tenerifensis IFM 10554T in the presence of animal cells
Yasumasa Hara, M. Arai, Kanae Sakai, Naoki Ishikawa +3 more
2017Journal of Natural Medicines15 citations
Semantic Scholar
Prenylflavonoids isolated from Artocarpus champeden with TRAIL-resistance overcoming activity.
T. Minakawa, K. Toume, M. Arai, T. Koyano +2 more
2013Phytochemistry15 citations
Semantic Scholar
Eudesmane-type sesquiterpenoid and guaianolides from Kandelia candel in a screening program for compounds to overcome TRAIL resistance.
T. Minakawa, K. Toume, M. Arai, S. Sadhu +2 more
2012Journal of Natural Products15 citations
Semantic Scholar
Identification of BMI1 Promoter Inhibitors from Beaumontia murtonii and Eugenia operculata.
Yui Kaneta, M. Arai, Naoki Ishikawa, K. Toume +5 more
2017Journal of Natural Products13 citations Open access
Semantic Scholar
Valosin‐containing Protein is a Target of 5′‐l Fuligocandin B and Enhances TRAIL Resistance in Cancer Cells
M. Arai, S. Taguchi, Kazuhiro Komatsuzaki, Kento Uchiyama +5 more
2016ChemistryOpen13 citations Open access
Semantic Scholar
Hes1-Binding Compounds Isolated by Target Protein Oriented Natural Products Isolation (TPO-NAPI).
M. Arai, Mitsuha Tanaka, Kana Tanouchi, Naoki Ishikawa +3 more
2017Journal of Natural Products12 citations Open access
Semantic Scholar
β-Sitosterol and flavonoids isolated from Bauhinia malabarica found during screening for Wnt signaling inhibitory activity
Hyun-Young Park, K. Toume, M. Arai, T. Koyano +2 more
2013Journal of Natural Medicines12 citations
Semantic Scholar
Hedgehog inhibitors from Artocarpus communis and Hyptis suaveolens.
M. Arai, Kyoko Uchida, S. Sadhu, F. Ahmed +3 more
2015Bioorganic & Medicinal Chemistry11 citations
Semantic Scholar
Methodology for awakening the potential secondary metabolic capacity in actinomycetes
Shun Saito, M. Arai
2024Beilstein Journal of Organic Chemistry9 citations Open access
Semantic Scholar
Dihydromaniwamycin E, a Heat-Shock Metabolite from Thermotolerant Streptomyces sp. JA74, Exhibiting Antiviral Activity against Influenza and SARS-CoV-2 Viruses
Shun Saito, Kayo Funayama, Wataru Kato, Mayu Okuda +12 more
2022Journal of Natural Products9 citations
Semantic Scholar
Isolation of nocobactin NAs as Notch signal inhibitors from Nocardia farcinica, a possibility of invasive evolution
M. Arai, Itsuki Ebihara, Yoshinori Makita, Yasumasa Hara +2 more
2020Journal of antibiotics (Tokyo. 1968)9 citations
Semantic Scholar
Cadinane sesquiterpenoids isolated from Santalum album using a screening program for Wnt signal inhibitory activity
Tomoyuki Sato, M. Arai, Yixizhuoma, Yasumasa Hara +3 more
2019Journal of Natural Medicines9 citations
Semantic Scholar
Identification of BMI1 promoter inhibitors from Streptomyces sp. IFM-11958.
Yusuke Yokoyama, M. Arai, Yasumasa Hara, M. Ishibashi
2019Bioorganic & Medicinal Chemistry9 citations
Semantic Scholar
Total synthesis of agalloside, isolated from Aquilaria agallocha, by the 5-O-glycosylation of flavan.
M. Arai, Yumi Yamaguchi, M. Ishibashi
2017Organic and biomolecular chemistry9 citations
Semantic Scholar
Synthesis of rocaglamide derivatives and evaluation of their Wnt signal inhibitory activities.
M. Arai, Yuuki Kofuji, Yuuki Tanaka, Natsuki Yanase +4 more
2016Organic and biomolecular chemistry9 citations
Semantic Scholar
Nonactin and related compounds found in a screening program for wnt signal inhibitory activity
Y. Tamai, K. Toume, M. Arai, A. Hayashida +4 more
20129 citations Open access
Semantic Scholar
Isolation and evaluation of cardenolides from Lansium domesticum as Notch inhibitors
Anna Tsuchiya, Yoshinori Makita, T. Koyano, T. Kowithayakorn +2 more
2020Journal of Natural Medicines8 citations
Semantic Scholar
Boehmenan, a lignan from Hibiscus ficulneus, showed Wnt signal inhibitory activity.
T. Shono, Naoki Ishikawa, K. Toume, M. Arai +3 more
2015Bioorganic & Medicinal Chemistry Letters8 citations
Semantic Scholar
Total syntheses of schizandriside, saracoside and (±)-isolariciresinol with antioxidant activities
Mana Sampei, M. Arai, M. Ishibashi
2018Journal of Natural Medicines7 citations
Semantic Scholar
Naturally occurring FANCF–Hes1 complex inhibitors from Wrightia religiosa
M. Arai, K. Uemura, Nozomi Hamahiga, Naoki Ishikawa +5 more
20157 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

M. Ishibashi×48
Invite
M. Ishibashi — researcher profile on SciRah
F. Ahmed×18
Invite
F. Ahmed — researcher profile on SciRah
K. Toume×17
Invite
K. Toume — researcher profile on SciRah
S. Sadhu×17
Invite
S. Sadhu — researcher profile on SciRah

×16

Invite

T. Koyano — researcher profile on SciRah

T. Kowithayakorn×16

Invite

T. Kowithayakorn — researcher profile on SciRah

Naoki Ishikawa×10

Invite

Naoki Ishikawa — researcher profile on SciRah

Yasumasa Hara×6

Invite

Yasumasa Hara — researcher profile on SciRah

Rolly G. Fuentes×4

Invite

Rolly G. Fuentes — researcher profile on SciRah

Invite

U. Karmakar — researcher profile on SciRah

Ryuta Akamine×4

Invite

Ryuta Akamine — researcher profile on SciRah

Yoshinori Makita×4

Invite

Yoshinori Makita — researcher profile on SciRah