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E. Newcombe · SciRah

Researcher profile · Semantic Scholar

E. Newcombe

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E. Newcombe — researcher profile on SciRah

h-index: 16
Works: 28
Citations: 1,614

Most-cited papers

Inflammation: the link between comorbidities, genetics, and Alzheimer’s disease
E. Newcombe, Judith Camats-Perna, M. L. Silva, Nicholas Valmas +2 more
2018Journal of Neuroinflammation462 citations Open access
Semantic Scholar
Metal Toxicity Links to Alzheimer’s Disease and Neuroinflammation
Tee Jong Huat, Judith Camats-Perna, E. Newcombe, Nicholas Valmas +2 more
2019Journal of Molecular Biology420 citations Open access
Semantic Scholar
Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles
S. Hennig, Geraldine Kong, Taro Mannen, Agata Sadowska +14 more
2015Journal of Cell Biology126 citations Open access
Semantic Scholar
Huntingtin Inclusions Trigger Cellular Quiescence, Deactivate Apoptosis, and Lead to Delayed Necrosis.
Yasmin M. Ramdzan, Mikhail M. Trubetskov, Angelique R. Ormsby, E. Newcombe +20 more
2017Cell Reports112 citations Open access
Semantic Scholar
How phosphorylation impacts intrinsically disordered proteins and their function
E. Newcombe, Elise Delaforge, R. Hartmann-Petersen, K. Skriver +1 more
2022Essays in Biochemistry79 citations Open access
Semantic Scholar
Tadpole-like conformations of huntingtin exon 1 are characterized by conformational heterogeneity that persists regardless of polyglutamine length
E. Newcombe, Kiersten M. Ruff, Ashish Sethi, Angelique R. Ormsby +6 more
2018Journal of Molecular Biology64 citations Open access
Semantic Scholar
The impact of astrocytic NF-κB on healthy and Alzheimer’s disease brains
Tee Jong Huat, Judith Camats-Perna, E. Newcombe, Tessa Onraet +8 more
2024Scientific Reports55 citations Open access
Semantic Scholar
Refinement of α-Synuclein Ensembles Against SAXS Data: Comparison of Force Fields and Methods
Mustapha Carab Ahmed, Line K. Skaanning, Alexander Jussupow, E. Newcombe +4 more
2021bioRxiv42 citations Open access
Semantic Scholar
Refinement of -Synuclein Ensembles Against SAXS Data Comparison of Force Fields and Methods
Mustapha Carab Ahmed, Line K. Skaanning, Alexander Jussupow, E. Newcombe +4 more
202139 citations
Semantic Scholar
Stereochemistry in the disorder–order continuum of protein interactions
E. Newcombe, Amanda D. Due, A. Sottini, Steffie Elkjær +11 more
2024Nature38 citations Open access
Semantic Scholar
Assessment of models for calculating the hydrodynamic radius of intrinsically disordered proteins
F. Pesce, E. Newcombe, Pernille Seiffert, Emil E. Tranchant +4 more
2022bioRxiv36 citations Open access
Semantic Scholar
Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins
E. Newcombe, Catarina B. Fernandes, Jeppe E. Lundsgaard, Inna Brakti +4 more
2021Biomolecules28 citations Open access
Semantic Scholar
EphA4 Regulates Hippocampal Neural Precursor Proliferation in the Adult Mouse Brain by d-Serine Modulation of N-Methyl-d-Aspartate Receptor Signaling.
Jing Zhao, Chanel J. Taylor, E. Newcombe, M. Spanevello +5 more
2019Cerebral Cortex24 citations
Semantic Scholar
Conformational dynamics and self-association of intrinsically disordered Huntingtin exon 1 in cells.
S. Büning, Abhishek Sharma, Shivang Vachharajani, E. Newcombe +6 more
2017Physical Chemistry, Chemical Physics - PCCP20 citations
Semantic Scholar
Deciphering the Alphabet of Disorder—Glu and Asp Act Differently on Local but Not Global Properties
Mette Ahrensback Roesgaard, Jeppe E. Lundsgaard, E. Newcombe, Nina L. Jacobsen +7 more
2022bioRxiv19 citations Open access
Semantic Scholar
Inflammation: the link between comorbidities, genetics, and Alzheimer’s disease
E. Newcombe, Judith Camats-Perna, M. L. Silva, Nicholas Valmas +2 more
2018Journal of Neuroinflammation18 citations Open access
Semantic Scholar
Monomeric α‐synuclein activates the plasma membrane calcium pump
Antoni Kowalski, C. Betzer, S. Larsen, E. Gregersen +14 more
2022bioRxiv15 citations Open access
Semantic Scholar
Targeted imaging of uPAR expression in vivo with cyclic AE105 variants
J. Leth, E. Newcombe, A. L. Grønnemose, J. Jørgensen +7 more
2023Scientific Reports8 citations Open access
Semantic Scholar
Deletion of MyD88 in astrocytes prevents β-amyloid-induced neuropathology in mice
Tee Jong Huat, Tessa Onraet, Judith Camats-Perna, E. Newcombe +5 more
2022Glia8 citations Open access
Semantic Scholar
Tadpole-like conformations of huntingtin exon 1 with expanded polyglutamine engenders novel interactions in cells
E. Newcombe, Kiersten M. Ruff, Ashish Sethi, Angelique R. Ormsby +6 more
2017bioRxiv3 citations Open access
Semantic Scholar
Understanding the biology of Huntington's disease via the pathogenic huntingtin monomer
E. Newcombe, Yasmin M. Ramdzan, Ashish Sethi, M. D. Lee +6 more
20151 citations
Semantic Scholar
The importance of stereochemistry in the disorder-order continuum of protein-protein interactions
E. Newcombe, Amanda D. Due, A. Sottini, Catarina B. Fernandes +9 more
2024bioRxiv0 citations Open access
Semantic Scholar
Enhancing the understanding of Huntington’s disease via structural and functional characterisation of the huntingtin monomer
E. Newcombe
20170 citations
Semantic Scholar
Tadpole-like conformations of huntingtin exon 1 with expanded polyglutamine 1 engenders novel interactions in cells 2
E. Newcombe, Kiersten M. Ruff, Ashish Sethi, Angelique R. Ormsby +7 more
20170 citations
Semantic Scholar
Comparative gene expression in developing cognitive circuits in common marmoset brain
M. Soskis, H. Ho, B. Ataman, C. Zhang +14 more
20120 citations
Semantic Scholar
Norepinephrine stimulates a distinct precursor population in the adult hippocampus
Dhanisha J. Jhaveri, E. Newcombe, V. Nink, G. Osborne +2 more
20120 citations
Semantic Scholar
A comparison of two new in vitro phototoxicity methods to a published yeast phototoxicity method
S. Rachui, T. Boufaissal, E. Newcombe, R. Allen
19960 citations
Semantic Scholar
Monomeric -synuclein activates the plasma membrane calcium pump
Antoni Kowalski, C. Betzer, S. Larsen, Thirup +23 more
0 citations
Semantic Scholar

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