Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

S. Scharpe · SciRah

Researcher profile · Semantic Scholar

S. Scharpe

Share profile

S. Scharpe — researcher profile on SciRah

h-index: 67
Works: 241
Citations: 16K

Most-cited papers

Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV
A. Lambeir, C. Durinx, S. Scharpe, I. De Meester
2003Critical reviews in clinical laboratory sciences938 citations
Semantic Scholar
Kynurenine pathway in major depression: evidence of impaired neuroprotection.
A. Myint, Y. Kim, R. Verkerk, S. Scharpe +2 more
2007Journal of Affective Disorders542 citations
Semantic Scholar
IDO and interferon-α-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity
M. Wichers, G. Koek, G. Robaeys, R. Verkerk +2 more
2005Molecular Psychiatry463 citations Open access
Semantic Scholar
Increased Serum Interleukin-8 in Patients with Early and Metastatic Breast Cancer Correlates with Early Dissemination and Survival
I. Benoy, R. Salgado, P. van Dam, K. Geboers +4 more
2004Clinical Cancer Research353 citations Open access
Semantic Scholar
Kinetic Investigation of Chemokine Truncation by CD26/Dipeptidyl Peptidase IV Reveals a Striking Selectivity within the Chemokine Family*
A. Lambeir, P. Proost, C. Durinx, G. Bal +5 more
2001Journal of Biological Chemistry287 citations Open access
Semantic Scholar
Molecular characterization of dipeptidyl peptidase activity in serum: soluble CD26/dipeptidyl peptidase IV is responsible for the release of X-Pro dipeptides.
C. Durinx, A. Lambeir, E. Bosmans, J. Falmagne +4 more
2000European Journal of Biochemistry278 citations
Semantic Scholar
Depressive and anxiety symptoms in the early puerperium are related to increased degradation of tryptophan into kynurenine, a phenomenon which is related to immune activation.
M. Maes, R. Verkerk, S. Bonaccorso, W. Ombelet +2 more
2002Life Science218 citations
Semantic Scholar
Dipeptidyl-peptidase IV converts intact B-type natriuretic peptide into its des-SerPro form.
Inger Brandt, A. Lambeir, J. Ketelslegers, M. Vanderheyden +2 more
2006Clinical Chemistry187 citations Open access
Semantic Scholar
Therapeutic drug monitoring of old and newer anti-epileptic drugs
H. Neels, A. Sierens, Kristine Naelaerts, S. Scharpe +2 more
2004Clinical Chemistry and Laboratory Medicine168 citations
Semantic Scholar
Cytokine Changes and Tryptophan Metabolites in Medication-Naïve and Medication-Free Schizophrenic Patients
Yong-Ku Kim, A. Myint, R. Verkerk, S. Scharpe +2 more
2009Neuropsychobiology145 citations
Semantic Scholar
Increased serum albumin, γ globulin, immunoglobulin IgG, and IgG2 and IgG4 in autism
J. Croonenberghs, A. Wauters, K. Devreese, R. Verkerk +5 more
2002Psychological Medicine144 citations
Semantic Scholar
Fluoro-olefins as peptidomimetic inhibitors of dipeptidyl peptidases.
P. Van der Veken, Kristel Senten, I. Kertész, I. De Meester +5 more
2005Journal of Medicinal Chemistry127 citations Open access
Semantic Scholar
Stimulatory effect of antidepressants on the production of IL-6.
M. Kubera, G. Kenis, E. Bosmans, M. Kajta +4 more
2004International Immunopharmacology126 citations
Semantic Scholar
Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile).
Inger Brandt, J. Joossens, Xin Chen, M. Maes +3 more
2005Biochemical Pharmacology120 citations
Semantic Scholar
The Role of Tryptophan Catabolism along the Kynurenine Pathway in Acute Ischemic Stroke
R. Brouns, R. Verkerk, T. Aerts, D. de Surgeloose +3 more
2010Neurochemical Research117 citations
Semantic Scholar
Reversal of imbalance between kynurenic acid and 3-hydroxykynurenine by antipsychotics in medication-naïve and medication-free schizophrenic patients.
A. Myint, M. Schwarz, R. Verkerk, H. H. Mueller +5 more
2011Brain, behavior, and immunity116 citations
Semantic Scholar
Tryptophan breakdown pathway in bipolar mania.
A. Myint, Yong-Ku Kim, R. Verkerk, Sun Hwa Park +3 more
2007Journal of Affective Disorders111 citations
Semantic Scholar
Kinetic study of the processing by dipeptidyl‐peptidase IV/CD26 of neuropeptides involved in pancreatic insulin secretion
A. Lambeir, C. Durinx, P. Proost, J. van Damme +2 more
2001FEBS Letters110 citations Open access
Semantic Scholar
Effects of Serotonin and Serotonergic Agonists and Antagonists on the Production of Interferon-γ and Interleukin-10
M. Kubera, G. Kenis, E. Bosmans, S. Scharpe +1 more
2000Neuropsychopharmacology104 citations
Semantic Scholar
Dipeptidyl peptidase IV inhibition improves cardiorenal function in overpacing‐induced heart failure
Nelson Gomez, Karim Touihri, V. Matheeussen, Agnès Mendes Da Costa +10 more
2012European Journal of Heart Failure102 citations
Semantic Scholar
Whole blood serotonin and platelet activation in depressed post-myocardial infarction patients.
A. Schins, K. Hamulýak, S. Scharpe, R. Lousberg +3 more
2004Life Science93 citations
Semantic Scholar
Natural substrates of dipeptidyl peptidase IV.
I. De Meester, C. Durinx, G. Bal, P. Proost +4 more
2000Advances in Experimental Medicine and Biology91 citations
Semantic Scholar
Prolyl oligopeptidase stimulates the aggregation of alpha-synuclein.
Inger Brandt, M. Gérard, K. Sergeant, B. Devreese +5 more
2008Peptides90 citations
Semantic Scholar
Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis
V. Matheeussen, Y. Waumans, W. Martinet, Sebastiaan Van Goethem +5 more
2013Basic Research in Cardiology87 citations
Semantic Scholar
Suggested functions for prolyl oligopeptidase: a puzzling paradox.
Inger Brandt, S. Scharpe, A. Lambeir
2007Clinica chimica acta; international journal of clinical chemistry86 citations
Semantic Scholar
Dipeptidyl peptidase IV substrates. An update on in vitro peptide hydrolysis by human DPPIV.
I. De Meester, A. Lambeir, P. Proost, S. Scharpe
2003Advances in Experimental Medicine and Biology84 citations
Semantic Scholar
Method comparison of dipeptidyl peptidase IV activity assays and their application in biological samples containing reversible inhibitors.
V. Matheeussen, A. Lambeir, W. Jungraithmayr, Nelson Gomez +4 more
2012Clinica chimica acta; international journal of clinical chemistry83 citations
Semantic Scholar
Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries
V. Matheeussen, Lesley Baerts, G. D. De Meyer, G. De Keulenaer +5 more
2011Biological chemistry76 citations
Semantic Scholar
Dipeptidyl peptidase 8/9‐like activity in human leukocytes
M. Maes, V. Dubois, Inger Brandt, A. Lambeir +6 more
2007Journal of Leukocyte Biology73 citations
Semantic Scholar
Dipeptidyl peptidase II (DPPII), a review.
M. Maes, S. Scharpe, I. De Meester
2007Clinica chimica acta; international journal of clinical chemistry73 citations
Semantic Scholar
Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7).
M. Maes, A. Lambeir, K. Gilany, Kristel Senten +5 more
2005Biochemical Journal66 citations Open access
Semantic Scholar
Effects of pregnancy and delivery on the availability of plasma tryptophan to the brain: relationships to delivery-induced immune activation and early post-partum anxiety and depression
M. Maes, W. Ombelet, R. Verkerk, E. Bosmans +1 more
2001Psychological Medicine66 citations
Semantic Scholar
Reference Values for Plasma Dipeptidyl Peptidase IV Activity and Their Association with Other Laboratory Parameters
C. Durinx, H. Neels, J. Van der Auwera, Kristine Naelaerts +2 more
2001Clinical Chemistry and Laboratory Medicine66 citations
Semantic Scholar
DPP4 inhibitors for diabetes--what next?
A. Lambeir, S. Scharpe, I. De Meester
2008Biochemical Pharmacology65 citations
Semantic Scholar
Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: isoindoline containing inhibitors.
Sebastiaan van Goethem, P. Van der Veken, V. Dubois, A. Soroka +6 more
2008Bioorganic & Medicinal Chemistry Letters63 citations Open access
Semantic Scholar
Serotonin-immune interactions in major depression: lower serum tryptophan as a marker of an immune-inflammatory response
M. Maes, R. Verkerk, Eric Vandoolaeghe, F. van Hunsel +4 more
2009European Archives of Psychiatry and Clinical Neuroscience59 citations
Semantic Scholar
Dipeptidyl-peptidase IV and B-type natriuretic peptide. From bench to bedside
M. Vanderheyden, J. Bartunek, M. Goethals, S. Verstreken +3 more
2009Clinical Chemistry and Laboratory Medicine57 citations
Semantic Scholar
Surprising findings following a Belgian food contamination with polychlorobiphenyls and dioxins.
P. Schepens, A. Covaci, P. Jorens, L. Hens +2 more
2001Environmental Health Perspectives54 citations Open access
Semantic Scholar
Carboxypeptidase M: Multiple alliances and unknown partners.
Kathleen Deiteren, D. Hendriks, S. Scharpe, A. Lambeir
2009Clinica chimica acta; international journal of clinical chemistry52 citations
Semantic Scholar
Irreversible inhibition of dipeptidyl peptidase 8 by dipeptide-derived diaryl phosphonates.
P. Van der Veken, A. Soroka, Inger Brandt, Yuan-Shou Chen +7 more
2007Journal of Medicinal Chemistry52 citations Open access
Semantic Scholar
Lower serum activity of prolyl endopeptidase in anorexia and bulimia nervosa.
M. Maes, P. Monteleone, R. Bencivenga, F. Goossens +4 more
2001Psychoneuroendocrinology51 citations
Semantic Scholar
Serotonergic disturbances in autistic disorder: L-5-hydroxytryptophan administration to autistic youngsters increases the blood concentrations of serotonin in patients but not in controls.
J. Croonenberghs, R. Verkerk, S. Scharpe, D. Deboutte +1 more
2005Life Science50 citations
Semantic Scholar
Lower Baseline Plasma Cortisol and Prolactin together with Increased Body Temperature and Higher mCPP-Induced Cortisol Responses in Men with Pedophilia
M. Maes, D. van West, Nathalie De Vos, H. Westenberg +4 more
2001Neuropsychopharmacology50 citations Open access
Semantic Scholar
Inhibition of CD26/DPP IV attenuates ischemia/reperfusion injury in orthotopic mouse lung transplants: the pivotal role of vasoactive intestinal peptide.
W. Jungraithmayr, I. De Meester, V. Matheeussen, I. Inci +4 more
2010Peptides47 citations Open access
Semantic Scholar
Psychobiological Aspects of Somatoform Disorders: Contributions of Monoaminergic Transmitter Systems
W. Rief, Florian Pilger, Daniel Ihle, R. Verkerk +2 more
2004Neuropsychobiology44 citations
Semantic Scholar
Enzyme Activity and Immunohistochemical Localization of Dipeptidyl Peptidase 8 and 9 in Male Reproductive Tissues
V. Dubois, C. Van Ginneken, H. De Cock, A. Lambeir +5 more
2009Journal of Histochemistry and Cytochemistry41 citations Open access
Semantic Scholar
Search for substrates for prolyl oligopeptidase in porcine brain.
Inger Brandt, K. De Vriendt, B. Devreese, J. Van Beeumen +5 more
2005Peptides40 citations
Semantic Scholar
Relative microvessel area of the primary tumour, and not lymph node status, predicts the presence of bone marrow micrometastases detected by reverse transcriptase polymerase chain reaction in patients with clinically non-metastatic breast cancer
I. Benoy, R. Salgado, H. Elst, P. van Dam +5 more
2005Breast Cancer Research38 citations Open access
Semantic Scholar
Intragraft DPP IV inhibition attenuates post-transplant pulmonary ischemia/reperfusion injury after extended ischemia.
W. Zhai, M. Cardell, I. De Meester, K. Augustyns +7 more
2007The Journal of Heart and Lung Transplantation37 citations
Semantic Scholar
Gamma-amino-substituted analogues of 1-[(S)-2,4-diaminobutanoyl]piperidine as highly potent and selective dipeptidyl peptidase II inhibitors.
Kristel Senten, P. Van der Veken, I. De Meester, A. Lambeir +3 more
2004Journal of Medicinal Chemistry37 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

I. De Meester×25
Invite
I. De Meester — researcher profile on SciRah
A. Lambeir×21
Invite
A. Lambeir — researcher profile on SciRah
K. Augustyns×15
Invite
K. Augustyns — researcher profile on SciRah
R. Verkerk×12
Invite
R. Verkerk — researcher profile on SciRah

P. Van der Veken

×9

Invite

P. Van der Veken — researcher profile on SciRah

Invite

M. Maes — researcher profile on SciRah

Inger Brandt×7

Invite

Inger Brandt — researcher profile on SciRah

Invite

C. Durinx — researcher profile on SciRah

Invite

M. Maes — researcher profile on SciRah

Invite

E. Bosmans — researcher profile on SciRah

Invite

A. Haemers — researcher profile on SciRah

Invite

Xin Chen — researcher profile on SciRah