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J. Noebels · SciRah

Researcher profile · Semantic Scholar

J. Noebels

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J. Noebels — researcher profile on SciRah

h-index: 79
Works: 296
Citations: 24K

Most-cited papers

Identification of diverse astrocyte populations and their malignant analogs
Chia-Ching John Lin, Kwan-Ha Yu, Asante Hatcher, Teng-Wei Huang +13 more
2017Nature Neuroscience477 citations Open access
Semantic Scholar
Silent Hippocampal Seizures and Spikes Identified by Foramen Ovale Electrodes in Alzheimer’s Disease
Alice D. Lam, G. Deck, A. Goldman, E. Eskandar +2 more
2017Nature Medicine344 citations Open access
Semantic Scholar
Spreading depolarization in the brainstem mediates sudden cardiorespiratory arrest in mouse SUDEP models
Isamu Aiba, J. Noebels
2015Science Translational Medicine320 citations Open access
Semantic Scholar
PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis
Kwan-Ha Yu, Chia-Ching John Lin, Asante Hatcher, B. Lozzi +13 more
2020Nature210 citations Open access
Semantic Scholar
Pathway-driven discovery of epilepsy genes
J. Noebels
2015Nature Neuroscience179 citations Open access
Semantic Scholar
Ion channels in genetic and acquired forms of epilepsy
H. Lerche, Mala M. Shah, H. Beck, J. Noebels +2 more
2013Journal of Physiology169 citations Open access
Semantic Scholar
Remote neuronal activity drives glioma progression via Sema4f
Emmet Huang-Hobbs, Yi-Ting Cheng, Yeunjung Ko, Estefanía Luna-Figueroa +20 more
2023Nature168 citations Open access
Semantic Scholar
Genetic Suppression of Transgenic APP Rescues Hypersynchronous Network Activity in a Mouse Model of Alzeimer's Disease
Heather A. Born, Ji-yoen Kim, Ricky R Savjani, Pritam Das +9 more
2014Journal of Neuroscience162 citations Open access
Semantic Scholar
Amyloid-beta / Fyn – Induced Synaptic , Network , and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer ’ s Disease
E. Roberson, Brian Halabisky, Jong W. Yoo, Jinghua Yao +9 more
2015161 citations
Semantic Scholar
Reduced cognition in Syngap1 mutants is caused by isolated damage within developing forebrain excitatory neurons
Emin D. Ozkan, T. Creson, E. Kramár, Camilo S. Rojas +9 more
2014Neuron137 citations Open access
Semantic Scholar
NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure
T. Eom, Chao-Lin Zhang, Huidong Wang, Kenneth Lay +3 more
2013eLife114 citations Open access
Semantic Scholar
Therapeutic inhibition of mTORC2 rescues the behavioral and neurophysiological abnormalities associated with Pten-deficiency.
Chien-Ju Chen, M. Sgritta, Jacqunae Mays, Hongyi Zhou +11 more
2019Nature Medicine109 citations Open access
Semantic Scholar
Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein
Mao-Xue Tang, G. Gao, C. Rueda, Hang Yu +16 more
2017Nature Communications104 citations Open access
Semantic Scholar
Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice
I. Ogiwara, H. Miyamoto, T. Tatsukawa, Tetsushi Yamagata +15 more
2018Communications Biology100 citations Open access
Semantic Scholar
Sudden unexpected death in epilepsy: Identifying risk and preventing mortality
S. Lhatoo, J. Noebels, V. Whittemore
2015Epilepsia100 citations Open access
Semantic Scholar
Epileptic Seizures in Alzheimer Disease: A Review
A. Horváth, A. Szücs, G. Barcs, J. Noebels +1 more
2016Alzheimer Disease and Associated Disorders91 citations
Semantic Scholar
Hyper-SUMOylation of the Kv7 Potassium Channel Diminishes the M-Current Leading to Seizures and Sudden Death
Yitao Qi, Jingxiong Wang, V. Bomben, De-Pei Li +8 more
2014Neuron89 citations Open access
Semantic Scholar
Pathogenesis of peritumoral hyperexcitability in an immunocompetent CRISPR-based glioblastoma model.
Asante Hatcher, Kwan-Ha Yu, J. Meyer, Isamu Aiba +2 more
2020Journal of Clinical Investigation87 citations Open access
Semantic Scholar
Ankyrin-G isoform imbalance and interneuronopathy link epilepsy and bipolar disorder
Angel Y. Lopez, Xinjun Wang, Ming-Xuan Xu, A. Maheshwari +6 more
2016Molecular Psychiatry80 citations Open access
Semantic Scholar
Glioma epileptiform activity and progression are driven by IGSF3-mediated potassium dysregulation
R. Curry, Isamu Aiba, J. Meyer, B. Lozzi +14 more
2023Neuron78 citations Open access
Semantic Scholar
αII Spectrin Forms a Periodic Cytoskeleton at the Axon Initial Segment and Is Required for Nervous System Function
C. Huang, Chuan-Sheng Zhang, T. Ho, J. Oses-Prieto +5 more
2017Journal of Neuroscience76 citations Open access
Semantic Scholar
Neonatal Estradiol Stimulation Prevents Epilepsy in Arx Model of X-Linked Infantile Spasms Syndrome
Pedro R. Olivetti, A. Maheshwari, J. Noebels
2014Science Translational Medicine67 citations Open access
Semantic Scholar
Monogenic models of absence epilepsy: windows into the complex balance between inhibition and excitation in thalamocortical microcircuits.
A. Maheshwari, J. Noebels
2014Progress in Brain Research65 citations
Semantic Scholar
Isolated P/Q Calcium Channel Deletion in Layer VI Corticothalamic Neurons Generates Absence Epilepsy
V. Bomben, Isamu Aiba, Jing Qian, M. Mark +2 more
2016Journal of Neuroscience62 citations Open access
Semantic Scholar
Bexarotene reduces network excitability in models of Alzheimer’s disease and epilepsy
V. Bomben, Jerrah K Holth, J. G. Reed, Paige E. Cramer +2 more
2014Neurobiology of Aging62 citations Open access
Semantic Scholar
Leaky RyR2 channels unleash a brainstem spreading depolarization mechanism of sudden cardiac death
Isamu Aiba, X. Wehrens, J. Noebels
2016Proceedings of the National Academy of Sciences of the United States of America60 citations Open access
Semantic Scholar
Mapt deletion fails to rescue premature lethality in two models of sodium channel epilepsy
Chun-Ling Chen, Jerrah K Holth, R. Bunton-Stasyshyn, Charles Anumonwo +3 more
2018Annals of Clinical and Translational Neurology58 citations Open access
Semantic Scholar
Postnatal Loss of P/Q-type Channels Confined to Rhombic Lip Derived Neurons Alters Synaptic Transmission at the Parallel Fiber to Purkinje Cell Synapse and Replicates Genomic Cacna1a Mutation Phenotype of Ataxia and Seizures in Mice
T. Maejima, Patric Wollenweber, Lena U.C. Teusner, J. Noebels +2 more
2013Journal of Neuroscience54 citations Open access
Semantic Scholar
Sub-genic intolerance, ClinVar, and the epilepsies: A whole-exome sequencing study of 29,165 individuals.
Joshua E. Motelow, G. Povysil, R. Dhindsa, Kate E. Stanley +251 more
2021American Journal of Human Genetics53 citations Open access
Semantic Scholar
Paradoxical proepileptic response to NMDA receptor blockade linked to cortical interneuron defect in stargazer mice
A. Maheshwari, Walter K. Nahm, J. Noebels
2013Frontiers in Cellular Neuroscience47 citations Open access
Semantic Scholar
Asynchronous suppression of visual cortex during absence seizures in stargazer mice
J. Meyer, A. Maheshwari, J. Noebels, S. Smirnakis
2018Nature Communications46 citations Open access
Semantic Scholar
Novel brain expression of ClC-1 chloride channels and enrichment of CLCN1 variants in epilepsy
Tim T. Chen, Tara L. Klassen, A. Goldman, C. Marini +2 more
2013Neurology46 citations Open access
Semantic Scholar
Glioblastoma disrupts cortical network activity at multiple spatial and temporal scales
J. Meyer, Kwan-Ha Yu, Estefanía Luna-Figueroa, B. Deneen +1 more
2023bioRxiv38 citations Open access
Semantic Scholar
Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation
E. Glasscock, N. Voigt, M. McCauley, Qiang Sun +10 more
2015Basic Research in Cardiology38 citations Open access
Semantic Scholar
Kcnq2/Kv7.2 controls the threshold and bi-hemispheric symmetry of cortical spreading depolarization
Isamu Aiba, J. Noebels
2020bioRxiv33 citations Open access
Semantic Scholar
Standards for data acquisition and software-based analysis of in vivo electroencephalography recordings from animals: A TASK1-WG5 report of the AES/ILAE Translational Task Force of the ILAE
J. T. Moyer, V. Gnatkovsky, Tomonori Ono, J. Otáhal +8 more
2017Epilepsia33 citations Open access
Semantic Scholar
Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing
M. Kole, Jing Qian, M. Waase, Tara L. Klassen +3 more
2015Journal of Neuroscience31 citations Open access
Semantic Scholar
Precision physiology and rescue of brain ion channel disorders
J. Noebels
2017The Journal of General Physiology30 citations Open access
Semantic Scholar
Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population
C. C. Hernandez, Tara L. Klassen, Laurel G. Jackson, Katharine N. Gurba +3 more
2016PLoS ONE30 citations Open access
Semantic Scholar
Single-Gene Determinants of Epilepsy Comorbidity.
J. Noebels
2015Cold Spring Harbor Perspectives in Medicine30 citations Open access
Semantic Scholar
Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms.
Qing-Long Miao, S. Herlitze, M. Mark, J. Noebels
2019Brain : a journal of neurology29 citations Open access
Semantic Scholar
The Epilepsy Spectrum: Targeting Future Research Challenges.
G. Holmes, J. Noebels
2016Cold Spring Harbor Perspectives in Medicine26 citations Open access
Semantic Scholar
The Role of Hyperexcitability in Gliomagenesis
Eric A. Goethe, B. Deneen, J. Noebels, Ganesh Rao
2023International Journal of Molecular Sciences25 citations Open access
Semantic Scholar
X-linked serotonin 2C receptor is associated with a non-canonical pathway for sudden unexpected death in epilepsy
C. Massey, Samantha J. Thompson, Ryan W Ostrom, J. Drabek +6 more
2021Brain Communications23 citations Open access
Semantic Scholar
How can advances in epilepsy genetics lead to better treatments and cures?
R. Guerrini, J. Noebels
2014Advances in Experimental Medicine and Biology23 citations
Semantic Scholar
β spectrin-dependent and domain specific mechanisms for Na+ channel clustering
Cheng-Hsin Liu, Ryan Seo, T. Ho, Michael C. Stankewich +4 more
2020eLife21 citations Open access
Semantic Scholar
Persistent aberrant cortical phase–amplitude coupling following seizure treatment in absence epilepsy models
A. Maheshwari, Abraham Akbar, Mai Wang, Rebecca L. Marks +4 more
2017Journal of Physiology20 citations Open access
Semantic Scholar
A hyperthermic seizure unleashes a surge of spreading depolarizations in Scn1a-deficient mice
Isamu Aiba, Yao Ning, J. Noebels
2023bioRxiv17 citations Open access
Semantic Scholar
Arx expansion mutation perturbs cortical development by augmenting apoptosis without activating innate immunity in a mouse model of X-linked infantile spasms syndrome
Meagan S. Siehr, C. Massey, J. Noebels
2020Disease Models & Mechanisms17 citations Open access
Semantic Scholar
Night Watch on the Titanic: Detecting Early Signs of Epileptogenesis in Alzheimer Disease
Alice D. Lam, J. Noebels
2020Epilepsy Currents15 citations Open access
Semantic Scholar

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B. Deneen×7
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B. Deneen — researcher profile on SciRah
Isamu Aiba×7
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Isamu Aiba — researcher profile on SciRah
A. Maheshwari×6
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A. Maheshwari — researcher profile on SciRah
Kwan-Ha Yu×4
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Asante Hatcher — researcher profile on SciRah

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C. Mohila — researcher profile on SciRah

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A. Goldman — researcher profile on SciRah

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B. Lozzi — researcher profile on SciRah

Emmet Huang-Hobbs×3

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Emmet Huang-Hobbs — researcher profile on SciRah

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Ganesh Rao — researcher profile on SciRah

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V. Bomben — researcher profile on SciRah

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J. Meyer — researcher profile on SciRah