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L. Bonham · SciRah

Researcher profile · Semantic Scholar

L. Bonham

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L. Bonham — researcher profile on SciRah

h-index: 24
Works: 86
Citations: 2,498

Most-cited papers

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score
R. Desikan, Chun-Chieh Fan, Yun-Peng Wang, A. Schork +30 more
2017PLoS Medicine371 citations Open access
Semantic Scholar
A second X chromosome contributes to resilience in a mouse model of Alzheimer’s disease
Emily J. Davis, L. Broestl, S. Abdulai-Saiku, Kurtresha Worden +23 more
2020Science Translational Medicine166 citations Open access
Semantic Scholar
Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease
J. Yokoyama, Yun-Peng Wang, A. Schork, W. Thompson +24 more
2016JAMA Neurology163 citations Open access
Semantic Scholar
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
Iris J. Broce, C. Karch, Natalie Wen, C. Fan +25 more
2018PLoS Medicine155 citations Open access
Semantic Scholar
Dissecting the clinical heterogeneity of early-onset Alzheimer’s disease
Daniel W. Sirkis, L. Bonham, T. Johnson, R. La Joie +1 more
2022Molecular Psychiatry128 citations Open access
Semantic Scholar
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer’s and Parkinson’s diseases
R. Ferrari, Yun-Peng Wang, J. Vandrovcova, S. Guelfi +18 more
2016Journal of Neurology Neurosurgery & Psychiatry119 citations Open access
Semantic Scholar
Polygenic hazard score: an enrichment marker for Alzheimer’s associated amyloid and tau deposition
Chin-Hong Tan, C. Fan, E. Mormino, L. Sugrue +20 more
2017bioRxiv97 citations Open access
Semantic Scholar
Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia
J. Yokoyama, C. Karch, C. Fan, L. Bonham +26 more
2017Acta Neuropathologica96 citations Open access
Semantic Scholar
Variation in longevity gene KLOTHO is associated with greater cortical volumes
J. Yokoyama, V. Sturm, L. Bonham, Erick Klein +7 more
2015Annals of Clinical and Translational Neurology91 citations Open access
Semantic Scholar
Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case–control study
Natasha Z. R. Steele, Jessie S. Carr, L. Bonham, Ethan G. Geier +13 more
2017PLoS Medicine84 citations Open access
Semantic Scholar
CXCR4 involvement in neurodegenerative diseases
L. Bonham, C. Karch, C. Fan, Chin-Hong Tan +21 more
2017bioRxiv79 citations Open access
Semantic Scholar
Polygenic hazard score, amyloid deposition and Alzheimer’s neurodegeneration
Chin-Hong Tan, L. Bonham, C. Fan, E. Mormino +20 more
2019Brain : a journal of neurology77 citations Open access
Semantic Scholar
Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging
J. Yokoyama, G. Marx, Jesse A. Brown, L. Bonham +7 more
2016Brain Imaging and Behavior69 citations Open access
Semantic Scholar
Non-Coding and Loss-of-Function Coding Variants in TET2 are Associated with Multiple Neurodegenerative Diseases
J. N. Cochran, Ethan G. Geier, L. Bonham, J. S. Newberry +10 more
2019bioRxiv68 citations Open access
Semantic Scholar
The relationship between complement factor C3, APOE ε4, amyloid and tau in Alzheimer’s disease
L. Bonham, R. Desikan, J. Yokoyama
2016Acta Neuropathologica Communications64 citations Open access
Semantic Scholar
Age‐dependent effects of APOE ε4 in preclinical Alzheimer's disease
L. Bonham, Ethan G. Geier, C. Fan, Josiah K. Leong +12 more
2016Annals of Clinical and Translational Neurology60 citations Open access
Semantic Scholar
Rare TREM2 variants associated with Alzheimer’s disease display reduced cell surface expression
Daniel W. Sirkis, L. Bonham, Renan Aparicio, Ethan G. Geier +7 more
2016Acta Neuropathologica Communications58 citations Open access
Semantic Scholar
Recent advances in the genetics of frontotemporal dementia
Daniel W. Sirkis, Ethan G. Geier, L. Bonham, C. Karch +1 more
2019Current Genetic Medicine Reports57 citations Open access
Semantic Scholar
Aging activates escape of the silent X chromosome in the female mouse hippocampus
Margaret Gadek, Cayce K. Shaw, S. Abdulai-Saiku, R. Saloner +9 more
2025Science Advances44 citations Open access
Semantic Scholar
Insulin-Like Growth Factor Binding Protein 2 Is Associated With Biomarkers of Alzheimer’s Disease Pathology and Shows Differential Expression in Transgenic Mice
L. Bonham, Ethan G. Geier, Natasha Z. R. Steele, D. Holland +4 more
2018Frontiers in Neuroscience44 citations Open access
Semantic Scholar
Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia
Ethan G. Geier, M. Bourdenx, Nadia J. Storm, J. Cochran +21 more
2018Acta Neuropathologica37 citations Open access
Semantic Scholar
Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes
L. Bonham, D. Evans, Yong-Mei Liu, S. Cummings +2 more
2018American Journal of Alzheimers Disease & Other Dementias28 citations Open access
Semantic Scholar
Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia
A. Friedberg, L. Pasquini, R. Diggs, E. A. Glaubitz +23 more
2023JAMA Neurology27 citations Open access
Semantic Scholar
Decision tree analysis of genetic risk for clinically heterogeneous Alzheimer’s disease
J. Yokoyama, L. Bonham, R. Sears, Erick Klein +4 more
2015BMC Neurology27 citations Open access
Semantic Scholar
Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy
Daniel W. Sirkis, Caroline Warly Solsberg, T. Johnson, L. Bonham +9 more
2022bioRxiv17 citations Open access
Semantic Scholar
Expansion of highly interferon-responsive T cells in early-onset Alzheimer’s disease
Daniel W. Sirkis, Caroline Warly Solsberg, T. Johnson, L. Bonham +5 more
2023bioRxiv16 citations Open access
Semantic Scholar
Apolipoprotein ε4 Is Associated with Lower Brain Volume in Cognitively Normal Chinese but Not White Older Adults
J. Yokoyama, Allen K. S. Lee, L. Takada, Edgar Busovaca +13 more
2015PLoS ONE16 citations Open access
Semantic Scholar
DNA methylation age from peripheral blood predicts progression to Alzheimer’s disease, white matter disease burden, and cortical atrophy
L. Bonham, Daniel W. Sirkis, A. Pang, L. Sugrue +5 more
2025npj Dementia15 citations Open access
Semantic Scholar
The role of interferon signaling in neurodegeneration and neuropsychiatric disorders
Daniel W. Sirkis, Alexis P. Oddi, C. Jonson, L. Bonham +2 more
2024Frontiers in Psychiatry15 citations Open access
Semantic Scholar
The Role of Microglia in Inherited White-Matter Disorders and Connections to Frontotemporal Dementia
Daniel W. Sirkis, L. Bonham, J. Yokoyama
2021The Application of Clinical Genetics15 citations Open access
Semantic Scholar
APOE Genotype Affects Cognitive Training Response in Healthy Shanghai Community-Dwelling Elderly Individuals
W. Feng, J. Yokoyama, Shun-Ying Yu, You Chen +6 more
2015Journal of Alzheimer's Disease15 citations Open access
Semantic Scholar
Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex
Yi Li, M. Barkovich, C. Karch, R. Nillo +21 more
2018Scientific Reports14 citations Open access
Semantic Scholar
Protein network analysis reveals selectively vulnerable regions and biological processes in FTD
L. Bonham, Natasha Z. R. Steele, C. Karch, C. Manzoni +14 more
2018Neurology: Genetics14 citations Open access
Semantic Scholar
The 5-HTTLPR variant in the serotonin transporter gene modifies degeneration of brain regions important for emotion in behavioral variant frontotemporal dementia
J. Yokoyama, L. Bonham, V. Sturm, Babu Adhimoolam +4 more
2015NeuroImage: Clinical14 citations Open access
Semantic Scholar
Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia
L. Bonham, Natasha Z. R. Steele, C. Karch, Iris J. Broce +166 more
2019Scientific Reports13 citations Open access
Semantic Scholar
Early‐onset Alzheimer's disease explained by polygenic risk of late‐onset disease?
William G. Mantyh, J. Cochran, Jared W. Taylor, Iris J. Broce +18 more
2023Alzheimer's & Dementia12 citations Open access
Semantic Scholar
Radiogenomics of C9orf72 Expansion Carriers Reveals Global Transposable Element Derepression and Enables Prediction of Thalamic Atrophy and Clinical Impairment
L. Bonham, Ethan G. Geier, Daniel W. Sirkis, Josiah K. Leong +21 more
2022Journal of Neuroscience12 citations Open access
Semantic Scholar
Identification of a rare coding variant in TREM2 in a Chinese individual with Alzheimer’s disease
L. Bonham, Daniel W. Sirkis, Jia Fan, Renan Aparicio +7 more
2017Neurocase12 citations Open access
Semantic Scholar
Immunological signatures in frontotemporal lobar degeneration
Daniel W. Sirkis, L. Bonham, C. Karch, J. Yokoyama
2019Current Opinion in Neurology10 citations Open access
Semantic Scholar
Personalized genetic assessment of age associated Alzheimer’s disease risk
R. Desikan, Chun-Chieh Fan, Yun-Peng Wang, A. Schork +30 more
2016bioRxiv10 citations Open access
Semantic Scholar
Frequency of frontotemporal dementia gene variants in C9ORF72, MAPT, and GRN in academic versus commercial laboratory cohorts
Natasha Z. R. Steele, Alison R. Bright, Suzee E. Lee, J. Fong +16 more
2018Advances in Genomics and Genetics9 citations Open access
Semantic Scholar
Alzheimer’s disease-associated cortical atrophy does not differ between Chinese and whites
Jia Fan, Marian Tse, Jessie S. Carr, B. Miller +4 more
2019Alzheimer Disease and Associated Disorders8 citations Open access
Semantic Scholar
Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
Iris J. Broce, C. Karch, Natalie Wen, C. Fan +25 more
2018PLoS Medicine8 citations Open access
Semantic Scholar
DNA methylation age from peripheral blood predicts progression to Alzheimer’s disease, white matter disease burden, and cortical atrophy
L. Bonham, Daniel W. Sirkis, A. Pang, Leo Sugrue +5 more
2024Research Square6 citations Open access
Semantic Scholar
C9orf72 gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell types
Iris J. Broce, Daniel W. Sirkis, R. Nillo, L. Bonham +7 more
2023bioRxiv6 citations Open access
Semantic Scholar
Frontotemporal lobar degeneration targets brain regions linked to expression of recently evolved genes
Lorenzo Pasquini, F. Pereira, Sahba Seddighi, Yi Zeng +20 more
2024Brain : a journal of neurology5 citations Open access
Semantic Scholar
Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case–control study
Natasha Z. R. Steele, Jessie S. Carr, L. Bonham, Ethan G. Geier +15 more
20175 citations
Semantic Scholar
Case Report: Novel CSF1R Variant in a Patient With Behavioral Variant Frontotemporal Dementia Syndrome With Prodromal Repetitive Scratching Behavior
A. Friedberg, E. Ramos, Zhongan Yang, L. Bonham +5 more
2022Frontiers in Neurology4 citations Open access
Semantic Scholar
Genetic overlap between cortical brain morphometry and frontotemporal dementia risk
S. Díaz-Torres, N. Ogonowski, Luis M. García-Marín, L. Bonham +3 more
2023Cerebral Cortex3 citations Open access
Semantic Scholar
High-Resolution MRI for Evaluation of Ventriculostomy Tubes: Assessment of Positioning and Proximal Patency
A. Blitz, P. Huynh, L. Bonham, S. Gujar +4 more
2020American Journal of Neuroradiology3 citations Open access
Semantic Scholar

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J. Yokoyama×42
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J. Yokoyama — researcher profile on SciRah
B. Miller×26
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B. Miller — researcher profile on SciRah
R. Desikan×20
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R. Desikan — researcher profile on SciRah
Daniel W. Sirkis×16
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Daniel W. Sirkis — researcher profile on SciRah

×14

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C. Karch — researcher profile on SciRah

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C. Hess — researcher profile on SciRah

Ethan G. Geier×13

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H. Rosen — researcher profile on SciRah