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J. Mcghee · SciRah

Researcher profile · Semantic Scholar

J. Mcghee

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J. Mcghee — researcher profile on SciRah

h-index: 71
Works: 334
Citations: 17K

Most-cited papers

Inside the Mucosal Immune System
J. Mcghee, K. Fujihashi
2012PLoS Biology228 citations Open access
Semantic Scholar
A dilemma for mucosal vaccination: efficacy versus toxicity using enterotoxin-based adjuvants.
K. Fujihashi, Toshiya Koga, F. V. van Ginkel, Y. Hagiwara +1 more
2002Vaccine201 citations
Semantic Scholar
Peyer's patches are required for oral tolerance to proteins
K. Fujihashi, T. Dohi, P. Rennert, M. Yamamoto +3 more
2001Proceedings of the National Academy of Sciences of the United States of America194 citations Open access
Semantic Scholar
Novel vaccine development strategies for inducing mucosal immunity
Yoshiko Fujkuyama, D. Tokuhara, K. Kataoka, R. Gilbert +4 more
2012Expert Review of Vaccines143 citations Open access
Semantic Scholar
Effective Mucosal Immunity to Anthrax: Neutralizing Antibodies and Th Cell Responses Following Nasal Immunization with Protective Antigen1
P. Boyaka, A. Tafaro, R. Fischer, S. Leppla +2 more
2003Journal of Immunology142 citations Open access
Semantic Scholar
RANTES Potentiates Antigen-Specific Mucosal Immune Responses1
James W. Lillard, P. Boyaka, D. Taub, J. Mcghee
2001Journal of Immunology123 citations Open access
Semantic Scholar
Pneumococcal carriage results in ganglioside-mediated olfactory tissue infection
F. V. van Ginkel, J. Mcghee, J. Watt, A. Campos-Torres +2 more
2003Proceedings of the National Academy of Sciences of the United States of America112 citations Open access
Semantic Scholar
MIP-1α and MIP-1β differentially mediate mucosal and systemic adaptive immunity
James W. Lillard, U. Singh, P. Boyaka, Shailesh Singh +2 more
200398 citations Open access
Semantic Scholar
HIV infection: first battle decides the war.
Z. Hel, J. Mcghee, J. Mestecky
2006Trends in immunology97 citations
Semantic Scholar
Elimination of Colonic Patches with Lymphotoxin β Receptor-Ig Prevents Th2 Cell-Type Colitis1
T. Dohi, P. Rennert, K. Fujihashi, H. Kiyono +4 more
2001Journal of Immunology97 citations Open access
Semantic Scholar
Protective Mucosal Immunity in Aging Is Associated with Functional CD4+ T Cells in Nasopharyngeal-Associated Lymphoreticular Tissue 1
Y. Hagiwara, J. Mcghee, K. Fujihashi, R. Kobayashi +9 more
2003Journal of Immunology92 citations Open access
Semantic Scholar
Enterotoxin-Based Mucosal Adjuvants Alter Antigen Trafficking and Induce Inflammatory Responses in the Nasal Tract
F. V. van Ginkel, R. Jackson, N. Yoshino, Y. Hagiwara +6 more
2005Infection and Immunity86 citations Open access
Semantic Scholar
The Pulmonary Environment Promotes Th2 Cell Responses After Nasal-Pulmonary Immunization with Antigen Alone, but Th1 Responses Are Induced During Instances of Intense Immune Stimulation1
Harlan P. Jones, Lisa Hodge, K. Fujihashi, H. Kiyono +2 more
2001Journal of Immunology81 citations Open access
Semantic Scholar
Role of Gut-Associated Lymphoreticular Tissues in Antigen-Specific Intestinal IgA Immunity1
M. Yamamoto, M. Kweon, P. Rennert, T. Hiroi +3 more
2004Journal of Immunology78 citations Open access
Semantic Scholar
Bacillus anthracis Edema Toxin Acts as an Adjuvant for Mucosal Immune Responses to Nasally Administered Vaccine Antigens1
A. Duverger, R. Jackson, F. V. van Ginkel, R. Fischer +6 more
2006Journal of Immunology74 citations Open access
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A nontoxic chimeric enterotoxin adjuvant induces protective immunity in both mucosal and systemic compartments with reduced IgE antibodies.
M. Kweon, M. Yamamoto, F. Watanabe, S. Tamura +8 more
2002Journal of Infectious Diseases73 citations Open access
Semantic Scholar
Immunoglobulin A (IgA) Responses and IgE-Associated Inflammation along the Respiratory Tract after Mucosal but Not Systemic Immunization
Lisa Hodge, M. Marinaro, Harlan P. Jones, J. Mcghee +2 more
2001Infection and Immunity70 citations Open access
Semantic Scholar
Genetically Manipulated Bacterial Toxin as a New Generation Mucosal Adjuvant
M. Yamamoto, J. Mcghee, Y. Hagiwara, S. Otake +1 more
2001Scandinavian Journal of Immunology70 citations
Semantic Scholar
A Combination of Flt3 Ligand cDNA and CpG ODN as Nasal Adjuvant Elicits NALT Dendritic Cells for Prolonged Mucosal Immunity
T. Fukuiwa, S. Sekine, R. Kobayashi, Hideaki Suzuki +7 more
2008Vaccine69 citations Open access
Semantic Scholar
Nasal Flt3 Ligand cDNA Elicits CD11c+CD8+ Dendritic Cells for Enhanced Mucosal Immunity1
K. Kataoka, J. Mcghee, R. Kobayashi, K. Fujihashi +2 more
2004Journal of Immunology68 citations Open access
Semantic Scholar
Mucosal immunity and tolerance in the elderly.
K. Fujihashi, J. Mcghee
2004Mechanisms of Ageing and Development67 citations
Semantic Scholar
Mucosal Vaccines: An Overview
P. Boyaka, J. Mcghee, C. Czerkinsky, J. Mestecky
2007Mucosal Immunology65 citations Open access
Semantic Scholar
Ovalbumin-protein sigma 1 M-cell targeting facilitates oral tolerance with reduction of antigen-specific CD4+ T cells.
Hideaki Suzuki, S. Sekine, K. Kataoka, D. Pascual +6 more
2008Gastroenterology64 citations Open access
Semantic Scholar
Oral QS-21 Requires Early IL-4 Help for Induction of Mucosal and Systemic Immunity1
P. Boyaka, M. Marinaro, R. Jackson, F. V. van Ginkel +4 more
2001Journal of Immunology63 citations Open access
Semantic Scholar
IFN-γ-Inducible Chemokines Enhance Adaptive Immunity and Colitis
U. Singh, Shailesh Singh, Nuzhat Iqbal, C. Weaver +2 more
200362 citations
Semantic Scholar
Lack of oral tolerance in aging is due to sequential loss of Peyer's patch cell interactions.
H. Kato, K. Fujihashi, R. Kato, T. Dohi +5 more
2003International Immunology59 citations Open access
Semantic Scholar
Chimeras of Labile Toxin One and Cholera Toxin Retain Mucosal Adjuvanticity and Direct Th Cell Subsets Via Their B Subunit1
P. Boyaka, M. Ohmura, K. Fujihashi, Toshiya Koga +7 more
2003Journal of Immunology59 citations
Semantic Scholar
Cytokines as adjuvants for the induction of mucosal immunity.
P. Boyaka, J. Mcghee
2001Advanced Drug Delivery Reviews56 citations
Semantic Scholar
Resistance of T-Cell Receptor δ-Chain-Deficient Mice to Experimental Candidaalbicans Vaginitis
F. Wormley, C. Steele, K. Wozniak, K. Fujihashi +2 more
2001Infection and Immunity55 citations Open access
Semantic Scholar
MIP-1alpha and MIP-1beta differentially mediate mucosal and systemic adaptive immunity.
James W. Lillard, U. Singh, P. Boyaka, Shailesh Singh +2 more
2003Blood54 citations
Semantic Scholar
Oral Tolerance Revisited: Prior Oral Tolerization Abrogates Cholera Toxin-Induced Mucosal IgA Responses1
H. Kato, K. Fujihashi, R. Kato, Y. Yuki +1 more
2001Journal of Immunology54 citations Open access
Semantic Scholar
A Second Generation of Double Mutant Cholera Toxin Adjuvants: Enhanced Immunity without Intracellular Trafficking1
Y. Hagiwara, Yuki I. Kawamura, K. Kataoka, Bibi Rahima +8 more
2006Journal of Immunology53 citations Open access
Semantic Scholar
Gut lymphocyte migration: we are halfway 'home'.
J. Mcghee, J. Kunisawa, H. Kiyono
2007Trends in immunology51 citations
Semantic Scholar
T helper type-2 cells induce ileal villus atrophy, goblet cell metaplasia, and wasting disease in T cell-deficient mice.
T. Dohi, K. Fujihashi, Toshiya Koga, Y. Shirai +5 more
2003Gastroenterology51 citations Open access
Semantic Scholar
Low-Dose Tolerance Is Mediated by the Microfold Cell Ligand, Reovirus Protein σ11
A. Rynda, M. Maddaloni, D. Mierzejewska, J. Ochoa-Repáraz +7 more
2008Journal of Immunology44 citations Open access
Semantic Scholar
A revisit of mucosal IgA immunity and oral tolerance
K. Fujihashi, H. Kato, F. V. van Ginkel, Toshiya Koga +9 more
2001Acta Odontologica Scandinavica44 citations Open access
Semantic Scholar
Protective immunity to Streptococcus mutans induced by nasal vaccination with surface protein antigen and mutant cholera toxin adjuvant.
Masayuki Saito, S. Otake, M. Ohmura, M. Hirasawa +7 more
2001Journal of Infectious Diseases40 citations
Semantic Scholar
Nasal immunization with E. coli verotoxin 1 (VT1)-B subunit and a nontoxic mutant of cholera toxin elicits serum neutralizing antibodies.
Youngjin Byun, M. Ohmura, K. Fujihashi, Shingo Yamamoto +6 more
2001Vaccine40 citations
Semantic Scholar
Therapeutic manipulation of the immune system: enhancement of innate and adaptive mucosal immunity.
P. Boyaka, A. Tafaro, R. Fischer, K. Fujihashi +2 more
2003Current pharmaceutical design39 citations
Semantic Scholar
A Novel Adenovirus Expressing Flt3 Ligand Enhances Mucosal Immunity by Inducing Mature Nasopharyngeal-Associated Lymphoreticular Tissue Dendritic Cell Migration1
S. Sekine, K. Kataoka, Y. Fukuyama, Y. Adachi +9 more
2008Journal of Immunology37 citations Open access
Semantic Scholar
Mucosal Vaccine Targeting Improves Onset of Mucosal and Systemic Immunity to Botulinum Neurotoxin A1
M. Maddaloni, Herman F. Staats, D. Mierzejewska, Teri R. Hoyt +7 more
2006Journal of Immunology37 citations Open access
Semantic Scholar
Pathological role of large intestinal IL-12p40 for the induction of Th2-type allergic diarrhea.
A. Hino, M. Kweon, K. Fujihashi, J. Mcghee +1 more
2004American Journal of Pathology37 citations Open access
Semantic Scholar
A Novel Neurotoxoid Vaccine Prevents Mucosal Botulism1
R. Kobayashi, T. Kohda, K. Kataoka, H. Ihara +6 more
2005Journal of Immunology36 citations
Semantic Scholar
A Novel Adjuvant for Mucosal Immunity to HIV-1 gp120 in Nonhuman Primates1
N. Yoshino, Fa-Bien X. Lu, K. Fujihashi, Y. Hagiwara +9 more
2004Journal of Immunology35 citations Open access
Semantic Scholar
Characterization of protective immune responses induced by nasal influenza vaccine containing mutant cholera toxin as a safe adjuvant (CT112K).
I. Watanabe, Y. Hagiwara, S. Kadowaki, T. Yoshikawa +9 more
2002Vaccine34 citations
Semantic Scholar
Host defenses at mucosal surfaces
K. Fujihashi, P. Boyaka, J. Mcghee
200833 citations
Semantic Scholar
IFN-gamma-inducible chemokines enhance adaptive immunity and colitis.
U. Singh, Shailesh Singh, Nuzhat Iqbal, C. Weaver +2 more
2003Journal of Interferon and Cytokine Research32 citations
Semantic Scholar
Adipose-Derived Mesenchymal Stem Cells Restore Impaired Mucosal Immune Responses in Aged Mice
K. Aso, Akitoshi Tsuruhara, K. Takagaki, K. Oki +10 more
2016PLoS ONE27 citations Open access
Semantic Scholar
Role of mucosal antibodies in viral infections.
H. Kato, R. Kato, K. Fujihashi, J. Mcghee
2001Current Topics in Microbiology and Immunology26 citations
Semantic Scholar
Low-dose tolerance is mediated by the microfold cell ligand, reovirus protein sigma1.
A. Rynda, M. Maddaloni, D. Mierzejewska, J. Ochoa-Repáraz +7 more
2008Journal of Immunology25 citations
Semantic Scholar

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K. Fujihashi×35
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P. Boyaka×14
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