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Chih-Kai Chao · SciRah

Researcher profile · Semantic Scholar

Chih-Kai Chao

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Chih-Kai Chao — researcher profile on SciRah

h-index: 10
Works: 27
Citations: 475

Most-cited papers

Cerebrospinal Fluid Biomarkers in Highly Exposed PM2.5 Urbanites: The Risk of Alzheimer’s and Parkinson’s Diseases in Young Mexico City Residents
L. Calderón-Garcidueñas, J. Ávila-Ramírez, A. Calderón-Garcidueñas, T. González-Heredia +11 more
2016Journal of Alzheimer's Disease100 citations
Semantic Scholar
Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer disease.
L. Calderón-Garcidueñas, Maricela Franco-Lira, A. D'Angiulli, Joel Rodríguez-Díaz +7 more
2015Environmental Research100 citations
Semantic Scholar
Brain immune interactions and air pollution: macrophage inhibitory factor (MIF), prion cellular protein (PrPC), Interleukin-6 (IL-6), interleukin 1 receptor antagonist (IL-1Ra), and interleukin-2 (IL-2) in cerebrospinal fluid and MIF in serum differentiate urban children exposed to severe vs. low ai
L. Calderón-Garcidueñas, J. V. Cross, Maricela Franco-Lira, Mariana Aragón-Flores +7 more
2013Frontiers in Neuroscience77 citations Open access
Semantic Scholar
Flavonol-rich dark cocoa significantly decreases plasma endothelin-1 and improves cognition in urban children
L. Calderón-Garcidueñas, A. Mora-Tiscareño, Maricela Franco-Lira, J. V. Cross +13 more
2013Frontiers in Pharmacology35 citations Open access
Semantic Scholar
Non-Phosphorylated Tau in Cerebrospinal Fluid is a Marker of Alzheimer’s Disease Continuum in Young Urbanites Exposed to Air Pollution
L. Calderón-Garcidueñas, P. Mukherjee, Katharina Waniek, M. Holzer +8 more
2018Journal of Alzheimer's Disease29 citations
Semantic Scholar
Determination of clindamycin in human plasma by liquid chromatography-electrospray tandem mass spectrometry: application to the bioequivalence study of clindamycin.
Li-Li Yu, Chih-Kai Chao, Wen-Jui Liao, Tyh-Yeuan Twu +3 more
1999Journal of Chromatography B: Biomedical Sciences and Applications27 citations
Semantic Scholar
Synthesis and Anti-Acetylcholinesterase Properties of Novel β- and γ-Substituted Alkoxy Organophosphonates
S. K. Ahmed, Yamina Belabassi, Lakshmi Sankaranarayanan, Chih-Kai Chao +2 more
2013Bioorganic & Medicinal Chemistry Letters16 citations Open access
Semantic Scholar
The inhibition, reactivation and mechanism of VX-, sarin-, fluoro-VX and fluoro-sarin surrogates following their interaction with HuAChE and HuBuChE.
Chih-Kai Chao, Narayanaganesh Balasubramanian, J. M. Gerdes, C. Thompson
2018Chemico-Biological Interactions14 citations Open access
Semantic Scholar
Novel Organophosphate Ligand O-(2-Fluoroethyl)-O-(p-Nitrophenyl)Methylphosphonate: Synthesis, Hydrolytic Stability and Analysis of the Inhibition and Reactivation of Cholinesterases
Chih-Kai Chao, S. K. Ahmed, J. M. Gerdes, C. Thompson
2016Chemical Research in Toxicology11 citations Open access
Semantic Scholar
Efficient digestion and mass spectral analysis of vesicular glutamate transporter 1: a recombinant membrane protein expressed in yeast.
Holly D. Cox, Chih-Kai Chao, S. Patel, C. Thompson
2008Journal of Proteome Research10 citations Open access
Semantic Scholar
CSF Biomarkers: Low Amyloid-β 1-42 and BDNF and High IFN γ Differentiate Children Exposed to Mexico City High Air Pollution V Controls. Alzheimer ’ s Disease Uncertainties
L. Calderón-Garcidueñas, Chih-Kai Chao, Charles M. Thompson, Joel Rodríguez-Díaz +3 more
20159 citations
Semantic Scholar
Oxidative stress resulting from exposure of a human salivary gland cells to paraoxon: an in vitro model for organophosphate oral exposure
J. Prins, Chih-Kai Chao, Saskia M Jacobson, C. Thompson +1 more
2014Toxicology in Vitro9 citations Open access
Semantic Scholar
VGLUT substrates and inhibitors: A computational viewpoint
C. Thompson, Chih-Kai Chao
2020Biochimica et Biophysica Acta - Biomembranes8 citations Open access
Semantic Scholar
CSF Biomarkers: Low Amyloid-ÃÂ²1-42 and BDNF and High IFN ÃÂ³Differentiate Children Exposed to Mexico City High Air Pollution VControls. AlzheimerÃ¢ÂÂs Disease Uncertainties
L. Calderón-Garcidueñas, Chih-Kai Chao, Charles M. Thompson, Joel Rodríguez-Díaz +3 more
20155 citations Open access
Semantic Scholar
Comparison of the reactivation rates of acetylcholinesterase modified by structurally different organophosphates using novel pyridinium oximes
Sandip B. Bharate, Chih-Kai Chao, C. Thompson
2019Environmental Toxicology and Pharmacology4 citations Open access
Semantic Scholar
Radiosynthesis, ex Vivo Biodistribution, and in Vivo Positron Emission Tomography Imaging Evaluations of [11C]2-Pyridinealdoxime Methiodide ([11C]2-PAM): A First-In-Class Antidote Tracer for Organophosphate Intoxication
Kiel D. Neumann, J. Blecha, Thomas R. Hayes, Tony L. Huynh +6 more
2018ACS Chemical Neuroscience4 citations Open access
Semantic Scholar
Bioequivalence Study of Tramadol by Intramuscular Administration in Healthy Volunteers
Chih-Kai Chao, Li-Li Yu, Li Su, Chu-Min Liu +2 more
2000Arzneimittelforschung4 citations
Semantic Scholar
Preparation and characterization of diethoxy- and monoethoxy phosphylated (‘aged’) serine haptens and use in the production of monoclonal antibodies
Yamina Belabassi, Chih-Kai Chao, R. Holly, K. George +2 more
2014Chemico-Biological Interactions3 citations Open access
Semantic Scholar
[11C]Paraoxon: Radiosynthesis, Biodistribution and In Vivo Positron Emission Tomography Imaging in Rat
T. Hayes, Chih-Kai Chao, J. Blecha, Tony L. Huynh +4 more
2023Journal of Pharmacology and Experimental Therapeutics2 citations Open access
Semantic Scholar
INHIBITION OF THE VESICULAR GLUTAMATE TRANSPORTER (VGLUT) WITH CONGO RED ANALOGS: NEW BINDING INSIGHTS.
D. M. Hitt, J. Zwicker, Chih-Kai Chao, S. Patel +3 more
2021Neurochemical Research2 citations Open access
Semantic Scholar
Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[18F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [18F]-VXS
Thomas R. Hayes, J. Blecha, Chih-Kai Chao, Tony L. Huynh +5 more
2020Annals of the New York Academy of Sciences2 citations Open access
Semantic Scholar
Biological Distribution and Metabolic Profiles of Carbon-11 and Fluorine-18 Tracers of VX- and Sarin-Analogs in Sprague–Dawley Rats
Thomas R. Hayes, Chih-Kai Chao, J. Blecha, Tony L. Huynh +4 more
2020Chemical Research in Toxicology2 citations Open access
Semantic Scholar
Inhibition of acetylcholinesterases by stereoisomeric organophosphorus compounds containing both thioester and p-nitrophenyl leaving groups.
T. Talley, Chih-Kai Chao, C. Berkman, R. Richardson +1 more
2020Chemical Research in Toxicology1 citations
Semantic Scholar
Dose Formulation, Biodistribution and PET Imaging Studies of a First-in-Class Fluorine-18 Organophosphorus Cholinesterase Inhibitor Tracer in Rat
Kiel D. Neumann, J. Blecha, Chih-Kai Chao, Tony L. Huynh +4 more
20201 citations
Semantic Scholar
Preparation of carbon-11-labeled surrogates of VX and sarin: Divergent radiosynthesis of 11C-tracers by modification of reaction conditions
Thomas R. Hayes, J. Blecha, Kiel D. Neumann, C. Thompson +4 more
20180 citations
Semantic Scholar
The vesicular glutamate transporter (VGLUT): Heterologous expression, proteoliposome, computational and mass spectral studies
Chih-Kai Chao
20080 citations
Semantic Scholar
Flavonol-Rich Dark Cocoa Significantly Decreases Plasma Flavonol-Rich Dark Cocoa Significantly Decreases Plasma Endothelin-1 and Improves Cognition in Urban Children Endothelin-1 and Improves Cognition in Urban Children
L. Calderón-Garcidueñas, A. Mora-Tiscareño, Maricela Franco-Lira, Jane Cross +14 more
0 citations
Semantic Scholar

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