Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Shao-Yi Sun · SciRah

Researcher profile · Semantic Scholar

Shao-Yi Sun

Share profile

Shao-Yi Sun — researcher profile on SciRah

h-index: 14
Works: 27
Citations: 581

Most-cited papers

Methyl-containing pharmaceuticals: Methylation in drug design.
Shao-Yi Sun, Jian-Min Fu
2018Bioorganic & Medicinal Chemistry Letters105 citations Open access
Semantic Scholar
Applications of amide isosteres in medicinal chemistry.
Shao-Yi Sun, Q. Jia, Zai-Hui Zhang
2019Bioorganic & Medicinal Chemistry Letters74 citations Open access
Semantic Scholar
NBI-921352, a first-in-class, NaV1.6 selective, sodium channel inhibitor that prevents seizures in Scn8a gain-of-function mice, and wild-type mice and rats
J. P. Johnson, T. Focken, Kuldip Khakh, P. K. Tari +46 more
2021bioRxiv51 citations Open access
Semantic Scholar
Inhibitors of voltage-gated sodium channel Nav1.7: patent applications since 2010.
Shao-Yi Sun, C. Cohen, Christoph M. Dehnhardt
2014Pharmaceutical Patent Analyst41 citations
Semantic Scholar
Discovery of Acyl-sulfonamide Nav1.7 Inhibitors GDC-0276 and GDC-0310.
B. Safina, Steven J McKerrall, Shao-Yi Sun, Chien-An Chen +43 more
2021Journal of Medicinal Chemistry34 citations Open access
Semantic Scholar
The discovery of benzenesulfonamide-based potent and selective inhibitors of voltage-gated sodium channel Na(v)1.7.
Shao-Yi Sun, Q. Jia, A. Zenova, M. Chafeev +8 more
2014Bioorganic & Medicinal Chemistry Letters34 citations Open access
Semantic Scholar
Tetracyclic spirooxindole blockers of hNaV1.7: activity in vitro and in CFA-induced inflammatory pain model
Sultan Chowdhury, Shi-Feng Liu, Jay A. Cadieux, Tom H. H. Hsieh +19 more
2013Medicinal Chemistry Research34 citations
Semantic Scholar
Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain.
T. Focken, Sultan Chowdhury, A. Zenova, Michael E. Grimwood +36 more
2018Journal of Medicinal Chemistry32 citations Open access
Semantic Scholar
Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (NaV) 1.7 with Potent Analgesic Activity.
Shao-Yi Sun, Q. Jia, A. Zenova, Michael S Wilson +34 more
2018Journal of Medicinal Chemistry31 citations Open access
Semantic Scholar
Discovery of piperazin-1-ylpyridazine-based potent and selective stearoyl-CoA desaturase-1 inhibitors for the treatment of obesity and metabolic syndrome.
Zai-Hui Zhang, Shao-Yi Sun, Vishnumurthy Kodumuru, Duanjie Hou +12 more
2013Journal of Medicinal Chemistry29 citations Open access
Semantic Scholar
Quinic acid esters and sesquiterpenes from Sonchus arvensis
Yang-Jun Xu, Shao-Yi Sun, Li-Mei Sun, Dong-Feng Qiu +3 more
200825 citations Open access
Semantic Scholar
Systematic evaluation of amide bioisosteres leading to the discovery of novel and potent thiazolylimidazolidinone inhibitors of SCD1 for the treatment of metabolic diseases.
Shao-Yi Sun, Zai-Hui Zhang, Vishnumurthy Kodumuru, N. Pokrovskaia +12 more
2014Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
Biologically active metabolites in drug discovery.
Shao-Yi Sun, S. Wesolowski
2021Bioorganic & Medicinal Chemistry Letters16 citations
Semantic Scholar
Discovery of XEN445: a potent and selective endothelial lipase inhibitor raises plasma HDL-cholesterol concentration in mice.
Shao-Yi Sun, R. Dean, Q. Jia, A. Zenova +12 more
2013Bioorganic & Medicinal Chemistry15 citations Open access
Semantic Scholar
Discovery of triazolone derivatives as novel, potent stearoyl-CoA desaturase-1 (SCD1) inhibitors.
Shao-Yi Sun, Zai-Hui Zhang, N. Pokrovskaia, Sultan Chowdhury +10 more
2015Bioorganic & Medicinal Chemistry12 citations Open access
Semantic Scholar
Discovery of thiazolylpyridinone SCD1 inhibitors with preferential liver distribution and reduced mechanism-based adverse effects.
Shao-Yi Sun, Zai-Hui Zhang, Vandna Raina, N. Pokrovskaia +11 more
2014Bioorganic & Medicinal Chemistry Letters11 citations Open access
Semantic Scholar
Identification of key enzymes involved in the accumulation of carotenoids during fruit ripening of Lycium barbarum L. by a proteomic approach
Xiaolu Zhao, Xi-Kang Zhang, J. Liu, Dong-Dong Li +5 more
2021International Journal of Food Science & Technology7 citations
Semantic Scholar
The contribution of NaV1.6 to the efficacy of voltage‐gated sodium channel inhibitors in wild type and NaV1.6 gain‐of‐function (GOF) mouse seizure control
James P. Johnson, T. Focken, Parisa Karimi Tari, Celine Dube +37 more
2024British Journal of Pharmacology5 citations Open access
Semantic Scholar
Identification of aryl sulfonamides as novel and potent inhibitors of NaV1.5.
Shao-Yi Sun, Q. Jia, A. Zenova, Sophia Lin +16 more
2021Bioorganic & Medicinal Chemistry Letters3 citations Open access
Semantic Scholar
Tetracyclic spirooxindole blockers of hNaV1.7: activity in vitro and in CFA-induced inflammatory pain model
Sultan Chowdhury, Shi-Feng Liu, Jay A. Cadieux, Tom H. H. Hsieh +19 more
2012Medicinal Chemistry Research2 citations
Semantic Scholar
NaV1.6 inhibition drives the efficacy of voltage-gated sodium channel inhibitors to prevent electrically induced seizures in both wild type and Scn8aN1768D/+ gain-of-function mice
JP Johnson, T. Focken, P. K. Tari, C. Dubé +37 more
2023bioRxiv1 citations Open access
Semantic Scholar
HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LPD LEVELS
N. Dales, Shao-Yi Sun, T. Devlin
20171 citations
Semantic Scholar
Discovery of Novel Bicyclic Pyrazole Amides as Potent Neuronal KV7 Potassium Channel Openers with Strong Preclinical Antiseizure Activity.
Shao-Yi Sun, Q. Jia, G. Bankar, Kristen N. Burford +21 more
2026ACS Medicinal Chemistry Letters0 citations Open access
Semantic Scholar
Discovery of novel cyclopentane carboxylic acids as potent and selective inhibitors of NaV1.7.
Shao-Yi Sun, Sultan Chowdhury, I. Hemeon, Abid Hasan +29 more
2024Bioorganic & Medicinal Chemistry Letters0 citations Open access
Semantic Scholar
Author response for "Identification of key enzymes involved in the accumulation of carotenoids during fruit ripening of Lycium barbarum L. by a proteomic approach"
Xiaolu Zhao, Xi-Kang Zhang, Jun Liu, Dong-Dong Li +5 more
20210 citations
Semantic Scholar
USE OF SPIRO-OXINDOLE COMPOUNDSAS THERAPEUTICAGENTS FIELD OF THE INVENTION
Shi-Feng Liu, CA Coquitlam, M. Bagherzadeh, S. Sviridov +3 more
20170 citations
Semantic Scholar
SPIRO-OXINDOLE-DERVATIVES AS SODIUM CHANNEL BLOCKERS FIELD OF THE INVENTION
Shao-Yi Sun
20170 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

Kuldip Khakh×14
Invite
Kuldip Khakh — researcher profile on SciRah
Q. Jia×13
Invite
Q. Jia — researcher profile on SciRah
Sultan Chowdhury×13
Invite
Sultan Chowdhury — researcher profile on SciRah
Christoph M. Dehnhardt×10
Invite
Christoph M. Dehnhardt — researcher profile on SciRah

×10

Invite

A. Zenova — researcher profile on SciRah

Zai-Hui Zhang×9

Invite

Zai-Hui Zhang — researcher profile on SciRah

Elaine Chang×9

Invite

Elaine Chang — researcher profile on SciRah

Invite

Sophia Lin — researcher profile on SciRah

Rainbow Kwan×9

Invite

Rainbow Kwan — researcher profile on SciRah

Invite

Jian-Min Fu — researcher profile on SciRah

Invite

G. Bankar — researcher profile on SciRah

Andrea Lindgren×8

Invite

Andrea Lindgren — researcher profile on SciRah