Researcher profile · Semantic Scholar

Y. L. Phua

h-index: 10
Works: 33
Citations: 351

Most-cited papers

Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival
Y. L. Phua, Jessica Y. S. Chu, April K. Marrone, Andrew J. Bodnar +2 more
2015Physiological Reports41 citations Open access
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Phenylketonuria oxidative stress and energy dysregulation: Emerging pathophysiological elements provide interventional opportunity
S. Dobrowolski, Y. L. Phua, J. Vockley, E. Goetzman +1 more
2022Molecular Genetics and Metabolism39 citations Open access
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Distinct sites of renal fibrosis in Crim1 mutant mice arise from multiple cellular origins
Y. L. Phua, N. Martel, David Pennisi, M. Little +1 more
2013Journal of Pathology37 citations
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Persistent DNA damage underlies tubular cell polyploidization and progression to chronic kidney disease in kidneys deficient in the DNA repair protein FAN1
Merlin Airik, Y. L. Phua, Amy B. Huynh, B. McCourt +7 more
2022Kidney International31 citations Open access
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Endothelial-Derived miR-17∼92 Promotes Angiogenesis to Protect against Renal Ischemia-Reperfusion Injury.
Takuto Chiba, D. Cerqueira, Yao Li, Andrew J. Bodnar +10 more
2021Journal of the American Society of Nephrology26 citations Open access
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Comparative metabolomics in the Pahenu2 classical PKU mouse identifies cerebral energy pathway disruption and oxidative stress
S. Dobrowolski, Y. L. Phua, Cayla Sudano, K. Spridik +5 more
2022Molecular Genetics and Metabolism21 citations Open access
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A MicroRNA Cluster miR-23–24–27 Is Upregulated by Aldosterone in the Distal Kidney Nephron Where it Alters Sodium Transport
Xiao-Ning Liu, R. Edinger, C. Klemens, Y. L. Phua +4 more
2017Journal of Cellular Physiology20 citations Open access
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Renal Dysplasia in the Neonate
Y. L. Phua, Jacqueline Ho
2016Current opinion in pediatrics18 citations Open access
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MicroRNAs in the pathogenesis of cystic kidney disease
Y. L. Phua, Jacqueline Ho
2015Current opinion in pediatrics16 citations Open access
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Mesenchymal stem cell energy deficit and oxidative stress contribute to osteopenia in the Pahenu2 classical PKU mouse
S. Dobrowolski, Cayla Sudano, Y. L. Phua, I. Tourkova +4 more
2021Molecular Genetics and Metabolism12 citations Open access
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Treatment of VLCAD de�cient patient �broblasts with peroxisome-proliferator activated receptor δ agonist improves cellular bioenergetics
O. D'Annibale, Y. L. Phua
202210 citations
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Phenylalanine hydroxylase deficient phenylketonuria comparative metabolomics identifies energy pathway disruption and oxidative stress.
S. Dobrowolski, Y. L. Phua, Cayla Sudano, K. Spridik +5 more
2021Molecular Genetics and Metabolism10 citations
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Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors.
Y. L. Phua, K. H. Chen, Shelby L. Hemker, April K. Marrone +6 more
2019AJP - Renal Physiology10 citations Open access
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Association between congenital defects in papillary outgrowth and functional obstruction in Crim1 mutant mice
Lorine Wilkinson, N. Kurniawan, Y. L. Phua, M. Nguyen +5 more
2012Journal of Pathology10 citations
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Mitochondrial ROS Triggers KIN Pathogenesis in FAN1-Deficient Kidneys
Merlin Airik, Haley Arbore, Elizabeth Childs, Amy B. Huynh +13 more
2023Antioxidants9 citations Open access
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Chromatin accessibility and microRNA expression in nephron progenitor cells during kidney development
Andrew S. Clugston, Andrew J. Bodnar, D. Cerqueira, Y. L. Phua +5 more
2021bioRxiv8 citations Open access
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The Lhx1-Ldb1 complex interacts with Furry to regulate microRNA expression during pronephric kidney development
Eugenel B. Espiritu, Amanda E. Crunk, A. Bais, D. Hochbaum +7 more
2018Scientific Reports8 citations Open access
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Neonatal vascularization and oxygen tension regulate appropriate perinatal renal medulla/papilla maturation
Y. L. Phua, T. Gilbert, Alexander N. Combes, Lorine Wilkinson +1 more
2016Journal of Pathology8 citations Open access
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A multiomics approach reveals evidence for phenylbutyrate as a potential treatment for combined D,L-2- hydroxyglutaric aciduria.
Y. L. Phua, O. D'Annibale, Anuradha Karunanidhi, A. Mohsen +3 more
2024Molecular Genetics and Metabolism5 citations Open access
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Small non-coding RNA expression in mouse nephrogenic mesenchymal progenitors
Y. L. Phua, Andrew S. Clugston, K. H. Chen, Dennis Kostka +1 more
2018Scientific Data5 citations Open access
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Glutamine energy substrate anaplerosis increases bone density in the Pahenu2 classical PKU mouse in the absence of phenylalanine restriction
S. Dobrowolski, Y. L. Phua, I. Tourkova, Cayla Sudano +3 more
2022JIMD Reports4 citations Open access
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An Infant with a Constellation of Biochemical Abnormalities.
Y. L. Phua, S. Dobrowolski
2021Clinical Chemistry2 citations
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P023: The clinical utility of plasma Lyso-Gb3 in the diagnosis of Fabry disease in infants and adults
Wen-jun Li, Brandon Stauffer, Hongjie Chen, Jing Xiao +6 more
2023Genetics in Medicine Open1 citations Open access
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Insights into the Regulation of Collecting Duct Homeostasis by Small Noncoding RNAs.
Y. L. Phua, Jacqueline Ho
2017Journal of the American Society of Nephrology1 citations Open access
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P727: Frequency of females with two phenylalanine hydroxylase gene variants and a potential mild phenotype in a reproductive carrier screening population
L. Abramson, Katherine Howard, N. Trikannad, Y. L. Phua +5 more
2026Genetics in Medicine Open0 citations Open access
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P065: Canonical splice variant c.298+2T>C in OTC associated with attenuated ornithine transcarbamylase deficiency
Janhawi Kelkar, Y. L. Phua, Chun-Li Yu, Colleen Donnelly +1 more
2025Genetics in Medicine Open0 citations Open access
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P031: Fabry disease: Genotype/phenotype correlations for 17 novel GLA mutations by GLA activity and plasma Lyso-Gb3 levels
Neal A. L. Cody, Y. L. Phua, Wen-jun Li, I. Nazarenko +7 more
2023Genetics in Medicine Open0 citations Open access
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A multiomics approach to understanding pathology of Combined D,L-2- Hydroxyglutaric Aciduria and phenylbutyrate as potential treatment
Y. L. Phua, O. D'Annibale, Anuradha Karunanidhi, A. Mohsen +3 more
2023bioRxiv0 citations Open access
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Loss of the mitochondrial citrate carrier, SLC25A1/CIC disrupts embryogenesis via 2-Hydroxyglutarate
A. Kasprzyk-Pawelec, Ming-Jun Tan, Y. L. Phua, R. Rahhal +17 more
20230 citations
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Persistent DNA Damage as a Driver of CKD and Tubular Cell Senescence
Rannar Airik, Merlin Airik, Y. L. Phua
2021Journal of the American Society of Nephrology0 citations
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The Lhx1-Ldb1 complex interacts with Furry to regulate microRNA expression during pronephric kidney development
Eugenel B. Espiritu, Amanda E. Crunk, A. Bais, D. Hochbaum +7 more
2018Scientific Reports0 citations Open access
Semantic Scholar
Small non-coding RNA expression in developing mouse nephron progenitor cells
Y. L. Phua, Andrew S. Clugston, K. H. Chen, Dennis Kostka +1 more
2018bioRxiv0 citations Open access
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The role of Crim1 in obstructive nephropathy and progressive renal fibrosis in the Crim1KST264/KST264 mice
Y. L. Phua
20130 citations
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