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Q. Tang · SciRah

Researcher profile · Semantic Scholar

Q. Tang

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Q. Tang — researcher profile on SciRah

h-index: 15
Works: 32
Citations: 756

Most-cited papers

Blood-based DNA methylation as biomarker for breast cancer: a systematic review
Q. Tang, Jie Cheng, Xue Cao, H. Surowy +1 more
2016Clinical Epigenetics156 citations Open access
Semantic Scholar
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment
Douglas D. Fang, Q. Tang, Y. Kong, Qixin Wang +7 more
2019Journal of Immunotherapy for Cancer135 citations Open access
Semantic Scholar
Grape-seed proanthocyanidins inhibit the lipopolysaccharide-induced inflammatory mediator expression in RAW264.7 macrophages by suppressing MAPK and NF-κb signal pathways.
Hongqian Chu, Q. Tang, Hongpeng Huang, Wei-Dong Hao +1 more
2016Environmental Toxicology and Pharmacology96 citations
Semantic Scholar
A plasma metabolite panel as biomarkers for early primary breast cancer detection
Bao-Wen Yuan, S. Schafferer, Q. Tang, M. Scheffler +10 more
2019International Journal of Cancer56 citations
Semantic Scholar
MDM2 inhibitor APG-115 exerts potent antitumor activity and synergizes with standard-of-care agents in preclinical acute myeloid leukemia models
Douglas D. Fang, Q. Tang, Y. Kong, Tao Rong +9 more
2021Cell Death Discovery49 citations Open access
Semantic Scholar
Cell-Free Circulating DNA Integrity Based on Peripheral Blood as a Biomarker for Diagnosis of Cancer: A Systematic Review
Jie Cheng, Q. Tang, Xue Cao, B. Burwinkel
2017Cancer Epidemiology, Biomarkers and Prevention41 citations Open access
Semantic Scholar
DNA methylation array analysis identifies breast cancer associated RPTOR, MGRN1 and RAPSN hypomethylation in peripheral blood DNA
Q. Tang, T. Holland-Letz, A. Slynko, K. Ćuk +17 more
2016OncoTarget36 citations Open access
Semantic Scholar
Let-7 g is involved in doxorubicin induced myocardial injury.
Jun Fu, Cike Peng, Wanyi Wang, Hai-Feng Jin +2 more
2012Environmental Toxicology and Pharmacology35 citations
Semantic Scholar
Evaluation of Promoter Methylation of RASSF1A and ATM in Peripheral Blood of Breast Cancer Patients and Healthy Control Individuals
Xue Cao, Q. Tang, T. Holland-Letz, M. Gündert +7 more
2018International Journal of Molecular Sciences25 citations Open access
Semantic Scholar
FLT3 inhibition by olverembatinib (HQP1351) downregulates MCL-1 and synergizes with BCL-2 inhibitor lisaftoclax (APG-2575) in preclinical models of FLT3-ITD mutant acute myeloid leukemia
Douglas D. Fang, Heng-Rui Zhu, Q. Tang, Guang-Feng Wang +5 more
2021Translational Oncology23 citations Open access
Semantic Scholar
MAP4K4 deletion inhibits proliferation and activation of CD4(+) T cell and promotes T regulatory cell generation in vitro.
Hongpeng Huang, Q. Tang, Hongqian Chu, Jianjun Jiang +3 more
2014Cellular Immunology21 citations
Semantic Scholar
Preclinical development of HQP1351, a multikinase inhibitor targeting a broad spectrum of mutant KIT kinases, for the treatment of imatinib-resistant gastrointestinal stromal tumors
Xue-Chao Liu, Guang-Feng Wang, Xiang-Lei Yan, Hai-Bo Qiu +12 more
2019Cell & Bioscience20 citations Open access
Semantic Scholar
Lisaftoclax in Combination with Alrizomadlin Overcomes Venetoclax Resistance in Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia: Preclinical Studies.
Y. Zhai, Q. Tang, Douglas D. Fang, Jing Deng +8 more
2022Clinical Cancer Research18 citations
Semantic Scholar
The effect of ethephon on immune system in male offspring of mice.
Siqi Wang, Hai-Feng Jin, Q. Tang, Jun Fu +5 more
2017Environmental Toxicology and Pharmacology16 citations
Semantic Scholar
Grape-seed proanthocyanidins ameliorate contact hypersensitivity induced by 2,4-dinitrofluorobenzene (DNFB) and inhibit T cell proliferation in vitro.
Q. Tang, Peng Zou, Hai-Feng Jin, Jun Fu +3 more
2012Toxicology Letters16 citations
Semantic Scholar
Comparative evaluation of the teratogenicity of genistein and genistin using rat whole embryo culture and limbud micromass culture methods.
Peng Zou, Li-Na Xing, Q. Tang, Ran Liu +1 more
2012Food and Chemical Toxicology5 citations
Semantic Scholar
MDM2 inhibitor APG-115 exerts potent antitumor activity and synergizes with standard-of-care agents in preclinical acute myeloid leukemia models
Douglas D. Fang, Q. Tang, Y. Kong, Tao Rong +9 more
2021Cell Death Discovery4 citations Open access
Semantic Scholar
Abstract 2058: BCL-2 selective inhibitor APG-2575 synergizes with BTK inhibitor in preclinical xenograft models of follicular lymphoma and diffuse large B-cell lymphoma
Douglas D. Fang, Guo-Qin Zhai, Shou-Lai Gu, R. Tao +11 more
2019Experimental and Molecular Therapeutics2 citations
Semantic Scholar
Investigation of Global Methylation in Peripheral Blood from Breast Cancer Patients
Xue Cao, T. Holland-Letz, Q. Tang, Xiaomeng Li +8 more
20172 citations Open access
Semantic Scholar
Abstract 2998: Inhibition of MDM2-p53 interaction by alrizomadlin (APG-115) induces pyroptotic cell death in gasdermin E (GSDME)-expressing cancer cells
Q. Tang, Douglas D. Fang, Hui-Dan Yu, Bingxin Wu +3 more
2022Cancer Research1 citations
Semantic Scholar
Abstract 3068: Synergistic effect of BCL-2 inhibitor APG-2575 and CDK9 inhibitor in acute myeloid leukemia and DLBCL preclinical tumor models
Douglas D. Fang, R. Tao, Q. Tang, Shou-Lai Gu +7 more
2019Experimental and Molecular Therapeutics1 citations
Semantic Scholar
Blood-based DNA methylation as biomarker for breast cancer: a systematic review
Q. Tang, Jie Cheng, Xue Cao, H. Surowy +1 more
2016Clinical Epigenetics1 citations Open access
Semantic Scholar
Abstract 3964: Co-targeting MDM2-p53 and BCL-2 apoptosis pathways overcomes resistance conferred by acquired BCL-2 gene mutations in preclinical models
Jing Deng, Kaixiang Zhang, Q. Tang, Xiao-Jing Huang +5 more
2022Cancer Research0 citations
Semantic Scholar
Abstract P208: Synergistic antitumor activity of lisaftoclax (APG-2575) and alrizomadlin (APG-115) through dual targeting of BCL-2/MDM2-P53 apoptotic pathways in preclinical models of acute myeloid leukemia
Douglas D. Fang, Q. Tang, Qixin Wang, Na Li +5 more
2021Poster Presentations - Proffered Abstracts0 citations
Semantic Scholar
Abstract 976: Inhibition of BCL-2 (by APG-2575) and CDK4/6 synergistically induces cell cycle arrest and apoptosis in ER+breast cancer
Jing Deng, R. Tao, Douglas D. Fang, Q. Tang +7 more
2021Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract P209: Collaborative crosstalk between two apoptosis pathways drives synergy of dual inhibition of BCL-2/MDM2 in preclinical models of neuroblastoma
Douglas D. Fang, Q. Tang, Qixin Wang, Y. Kong +5 more
2021Poster Presentations - Proffered Abstracts0 citations
Semantic Scholar
Abstract 981: BCL-2 inhibitor APG-2575 and homoharringtonine (HHT) synergistically induces apoptosis and inhibits tumor growth in preclinical models of acute myeloid leukemia and myelodysplastic syndromes (AML/MDS)
Douglas D. Fang, Q. Tang, Y. Kong, Tao Rong +4 more
2021Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 1096: FMS-like tyrosine kinase 3 (FLT3) inhibition by olverembatinib (HQP1351) downregulates MCL-1 and synergizes with BCL-2 inhibitor APG-2575 in preclinical models of FLT3-mutant acute myeloid leukemia (AML)
Douglas D. Fang, Heng-Rui Zhu, Q. Tang, Qixin Wang +6 more
2021Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 6233: APG-2575, a clinical stage BCL-2 selective inhibitor, sensitizes estrogen receptor-positive breast cancers to standard therapies in the preclinical models
Douglas D. Fang, Q. Tang, R. Tao, Guo-Qin Zhai +3 more
2020Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 4217: Synergy of tyrosine kinase inhibitor HQP1351 and MDM2-P53 antagonist, APG-115, in preclinical models ofFLT3mutant andTP53wild-type acute myeloid leukemia
Douglas D. Fang, Q. Tang, Qixin Wang, Na Li +7 more
2020Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 3192: Activation of p53 in the tumor microenvironment by MDM2 inhibitor APG-115 synergizes with PD-1 blockade independently of p53 status of tumor cells
Douglas D. Fang, Q. Tang, Y. Kong, Qixin Wang +7 more
2019Immunology0 citations
Semantic Scholar
Identification of a blood based metabolomic classifer for the detection of ovarian cancer – MeDOC
J. Nees, S. Schott, S. Schafferer, U. Müller +9 more
2018Geburtshilfe und Frauenheilkunde0 citations
Semantic Scholar

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